메뉴 건너뛰기




Volumn 22, Issue 8, 2013, Pages 993-1005

IL-17 targeted therapies for psoriasis

Author keywords

Anti IL 17 agents; Brodalumab; IL 17; Ixekizumab; Psoriasis; Secukinumab

Indexed keywords

ADALIMUMAB; BRODALUMAB; INTERLEUKIN 17; INTERLEUKIN 17B; INTERLEUKIN 17C; INTERLEUKIN 17F; INTERLEUKIN 25; INTERLEUKIN 27; IXEKIZUMAB; PROTEIN; SECUKINUMAB; UNCLASSIFIED DRUG; USTEKINUMAB;

EID: 84880248483     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2013.806483     Document Type: Review
Times cited : (142)

References (99)
  • 1
    • 33745727343 scopus 로고    scopus 로고
    • Epidemiology of psoriasis review and the german perspective
    • Schäfer T. Epidemiology of psoriasis. Review and the German perspective. Dermatology 2006;212(4):327-37
    • (2006) Dermatology , vol.212 , Issue.4 , pp. 327-337
    • Schäfer, T.1
  • 2
    • 70350506810 scopus 로고    scopus 로고
    • Psoriasis - a systemic inflammatory disorder: Clinic, pathogenesis and therapeutic perspectives
    • Boehncke WH, Sterry W. Psoriasis - a systemic inflammatory disorder: Clinic, pathogenesis and therapeutic perspectives. J Dtsch Dermatol Ges 2009;7(11):946-52
    • (2009) J Dtsch Dermatol Ges , vol.7 , Issue.11 , pp. 946-952
    • Boehncke, W.H.1    Sterry, W.2
  • 3
    • 77953611927 scopus 로고    scopus 로고
    • Psoriasis and systemic inflammatory diseases: Potential mechanistic links between skin disease and co-morbid conditions
    • Davidovici BB, Sattar N, Prinz J, et al. Psoriasis and systemic inflammatory diseases: Potential mechanistic links between skin disease and co-morbid conditions. J Invest Dermatol 2010;130(7):1785-96
    • (2010) J Invest Dermatol , vol.130 , Issue.7 , pp. 1785-1796
    • Davidovici, B.B.1    Sattar, N.2    Prinz, J.3
  • 4
    • 6344244643 scopus 로고    scopus 로고
    • Psoriatic arthritis
    • Gladman DD. Psoriatic arthritis. Dermatol Ther 2004;17(5):350-63
    • (2004) Dermatol Ther , vol.17 , Issue.5 , pp. 350-363
    • Gladman, D.D.1
  • 5
    • 29144457541 scopus 로고    scopus 로고
    • Impact of obesity and smoking on psoriasis presentation and management
    • Herron MD, Hinckley M, Hoffman MS, et al. Impact of obesity and smoking on psoriasis presentation and management. Arch Dermatol 2005;141(12):1527-34
    • (2005) Arch Dermatol , vol.141 , Issue.12 , pp. 1527-1534
    • Herron, M.D.1    Hinckley, M.2    Hoffman, M.S.3
  • 6
    • 33751181855 scopus 로고    scopus 로고
    • Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
    • Sommer DM, Jenisch S, Suchan M, et al. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res 2006;298(7):321-8
    • (2006) Arch Dermatol Res , vol.298 , Issue.7 , pp. 321-328
    • Sommer, D.M.1    Jenisch, S.2    Suchan, M.3
  • 7
    • 36148992304 scopus 로고    scopus 로고
    • Psoriasis patients show signs of insulin resistance
    • Boehncke S, Thaci D, Beschmann H, et al. Psoriasis patients show signs of insulin resistance. Br J Dermatol 2007;157(6):1249-51
    • (2007) Br J Dermatol , vol.157 , Issue.6 , pp. 1249-1251
    • Boehncke, S.1    Thaci, D.2    Beschmann, H.3
  • 9
    • 0021903859 scopus 로고
    • High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients
    • Ena P, Madeddu P, Glorioso N, et al. High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients. Acta Cardiol 1985;40(2):199-205
    • (1985) Acta Cardiol , vol.40 , Issue.2 , pp. 199-205
    • Ena, P.1    Madeddu, P.2    Glorioso, N.3
  • 10
    • 0018189501 scopus 로고
    • Psoriasis and occlusive vascular disease
    • Mcdonald CJ, Calabresi P. Psoriasis and occlusive vascular disease. Br J Dermatol 1978;99(5):469-75
    • (1978) Br J Dermatol , vol.99 , Issue.5 , pp. 469-475
    • Mcdonald, C.J.1    Calabresi, P.2
  • 11
    • 33749613119 scopus 로고    scopus 로고
    • Risk of myocardial infarction in patients with psoriasis
    • Gelfand JM, Neimann AL, Shin DB, et al. Risk of myocardial infarction in patients with psoriasis. JAMA 2006;296(14):1735-41
    • (2006) JAMA , vol.296 , Issue.14 , pp. 1735-1741
    • Gelfand, J.M.1    Neimann, A.L.2    Shin, D.B.3
  • 12
    • 84859134167 scopus 로고    scopus 로고
    • Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: A cohort study
    • Li WQ, Han JL, Manson JE, et al. Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: A cohort study. Br J Dermatol 2012;166(4):811-18
    • (2012) Br J Dermatol , vol.166 , Issue.4 , pp. 811-818
    • Li, W.Q.1    Han, J.L.2    Manson, J.E.3
  • 13
    • 76349121073 scopus 로고    scopus 로고
    • Psoriasis and hypertension: A case-control study
    • Cohen AD, Weitzman D, Dreiher J. Psoriasis and hypertension: A case-control study. Acta Derm Venereol 2010;90(1):23-6
    • (2010) Acta Derm Venereol , vol.90 , Issue.1 , pp. 23-26
    • Cohen, A.D.1    Weitzman, D.2    Dreiher, J.3
  • 14
    • 32944481369 scopus 로고    scopus 로고
    • An Italian study on psoriasis and depression
    • Esposito M, Saraceno R, Giunta A, et al. An Italian study on psoriasis and depression. Dermatology 2006;212(2):123-7
    • (2006) Dermatology , vol.212 , Issue.2 , pp. 123-127
    • Esposito, M.1    Saraceno, R.2    Giunta, A.3
  • 15
    • 0032872277 scopus 로고    scopus 로고
    • Psoriasis causes as much disability as other major medical diseases
    • Rapp SR, Feldman SR, Exum ML, et al. Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 1999;41(3 Pt 1):401-570
    • (1999) J Am Acad Dermatol , vol.41 , Issue.3 PART 1 , pp. 401-570
    • Rapp, S.R.1    Feldman, S.R.2    Exum, M.L.3
  • 16
    • 77957099018 scopus 로고    scopus 로고
    • Health economics and the modern management of psoriasis
    • Burden AD. Health economics and the modern management of psoriasis. Br J Dermatol 2010;163(4):670-1
    • (2010) Br J Dermatol , vol.163 , Issue.4 , pp. 670-671
    • Burden, A.D.1
  • 17
    • 0036404934 scopus 로고    scopus 로고
    • Experiences of stigmatization play a role in mediating the impact of disease severity on quality of life in psoriasis patients
    • Vardy D, Besser A, Amir M, et al. Experiences of stigmatization play a role in mediating the impact of disease severity on quality of life in psoriasis patients. Br J Dermatol 2002;147(4):736-42
    • (2002) Br J Dermatol , vol.147 , Issue.4 , pp. 736-742
    • Vardy, D.1    Besser, A.2    Amir, M.3
  • 18
    • 70249137988 scopus 로고    scopus 로고
    • European S3-guidelines on the systemic treatment of psoriasis vulgaris
    • Pathirana D, Ormerod AD, Saiag P, et al. European S3-guidelines on the systemic treatment of psoriasis vulgaris. J Eur Acad Dermatol Venereol 2009;23(Suppl 2):1-70
    • (2009) J Eur Acad Dermatol Venereol , vol.23 , Issue.SUPPL. 2 , pp. 1-70
    • Pathirana, D.1    Ormerod, A.D.2    Saiag, P.3
  • 19
    • 77949865934 scopus 로고    scopus 로고
    • The status of biologic therapies in the treatment of moderate to severe psoriasis
    • Menter A. The status of biologic therapies in the treatment of moderate to severe psoriasis. Cutis 2009;84:14-24
    • (2009) Cutis , vol.84 , pp. 14-24
    • Menter, A.1
  • 20
    • 33846889522 scopus 로고    scopus 로고
    • A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
    • Krueger GG, Langley RG, Leonardi C, et al. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N Engl J Med 2007;356:580-92
    • (2007) N Engl J Med , vol.356 , pp. 580-592
    • Krueger, G.G.1    Langley, R.G.2    Leonardi, C.3
  • 21
    • 42149087160 scopus 로고    scopus 로고
    • Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells
    • Lowes MA, Kikuchi T, Fuentes-Duculan J, et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J Invest Dermatol 2008;128:1207-11
    • (2008) J Invest Dermatol , vol.128 , pp. 1207-1211
    • Lowes, M.A.1    Kikuchi, T.2    Fuentes-Duculan, J.3
  • 22
    • 69349093225 scopus 로고    scopus 로고
    • Interleukin-17 and type 17 helper T cells
    • Miossec P, Korn T, Kuchroo VK. Interleukin-17 and type 17 helper T cells. N Engl J Med 2009;361:888-98
    • (2009) N Engl J Med , vol.361 , pp. 888-898
    • Miossec, P.1    Korn, T.2    Kuchroo, V.K.3
  • 24
    • 0027215897 scopus 로고
    • CTLA 8, cloned from an activated T cell, bearing AU rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
    • Rouvier E, Luciani MF, Mattei MG, et al. CTLA 8, cloned from an activated T cell, bearing AU rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J Immunol 1993;150:5445-56
    • (1993) J Immunol , vol.150 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.F.2    Mattei, M.G.3
  • 25
    • 0028858556 scopus 로고
    • Human IL-17: A novel cytokine derived from T cells
    • Yao Z, Painter SL, Fanslow WC, et al. Human IL-17: A novel cytokine derived from T cells. J Immunol 1995;155(12):5483-6
    • (1995) J Immunol , vol.155 , Issue.12 , pp. 5483-5486
    • Yao, Z.1    Painter, S.L.2    Fanslow, W.C.3
  • 26
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005;6:1123-32
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 27
    • 69449095507 scopus 로고    scopus 로고
    • IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
    • Ortega C, Fernandez AS, Carrillo JM, et al. IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. J Leukoc Biol 2009;86:435-43
    • (2009) J Leukoc Biol , vol.86 , pp. 435-443
    • Ortega, C.1    Fernandez, A.S.2    Carrillo, J.M.3
  • 28
    • 80052661515 scopus 로고    scopus 로고
    • Identification of a novel pro-inflammatory human skin-homing Vc9Vd2 T cell subset with a potential role in psoriasis
    • Laggner U, Di Meglio P, Perera G, et al. Identification of a novel pro-inflammatory human skin-homing Vc9Vd2 T cell subset with a potential role in psoriasis. J Immunol 2011;187:2783-93
    • (2011) J Immunol , vol.187 , pp. 2783-2793
    • Laggner, U.1    Di Meglio, P.2    Perera, G.3
  • 29
    • 79959584686 scopus 로고    scopus 로고
    • Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis
    • Lin AM, Rubin CJ, Khandpur R, et al. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol 2011;187:490-500
    • (2011) J Immunol , vol.187 , pp. 490-500
    • Lin, A.M.1    Rubin, C.J.2    Khandpur, R.3
  • 30
    • 80053600391 scopus 로고    scopus 로고
    • Recent advances in the il-17 cytokine family
    • Gaffen SL. Recent advances in the IL-17 cytokine family. Curr Opin Immunol 2011;23(5):613-19
    • (2011) Curr Opin Immunol , vol.23 , Issue.5 , pp. 613-619
    • Gaffen, S.L.1
  • 31
    • 68849084891 scopus 로고    scopus 로고
    • Structure and signalling in the IL-17 receptor family
    • Gaffen SL. Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 2009;9:556-67
    • (2009) Nat Rev Immunol , vol.9 , pp. 556-567
    • Gaffen, S.L.1
  • 32
    • 17944368518 scopus 로고    scopus 로고
    • IL-17s adopt a cysteine knot fold: Structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
    • Hymowitz SG, Filvaroff EH, Yin JP, et al. IL-17s adopt a cysteine knot fold: Structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J 2001;20:5332-41
    • (2001) EMBO J , vol.20 , pp. 5332-5341
    • Hymowitz, S.G.1    Filvaroff, E.H.2    Yin, J.P.3
  • 34
    • 0036644547 scopus 로고    scopus 로고
    • New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25
    • Hurst SD, Muchamuel T, Gorman DM, et al. New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25. J Immunol 2002;169:443-53
    • (2002) J Immunol , vol.169 , pp. 443-453
    • Hurst, S.D.1    Muchamuel, T.2    Gorman, D.M.3
  • 35
    • 0036785392 scopus 로고    scopus 로고
    • Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production
    • Kim MR, Manoukian R, Yeh R, et al. Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood 2002;100:2330-40
    • (2002) Blood , vol.100 , pp. 2330-2340
    • Kim, M.R.1    Manoukian, R.2    Yeh, R.3
  • 36
    • 11144286392 scopus 로고    scopus 로고
    • Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection
    • Kelly MN, Kolls JK, Happel K, et al. Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun 2005;73:617-21
    • (2005) Infect Immun , vol.73 , pp. 617-621
    • Kelly, M.N.1    Kolls, J.K.2    Happel, K.3
  • 37
    • 17944364849 scopus 로고    scopus 로고
    • Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
    • Ye P, Rodriguez FH, Kanaly S, et al. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J Exp Med 2001;194(4):519-27
    • (2001) J Exp Med , vol.194 , Issue.4 , pp. 519-527
    • Ye, P.1    Rodriguez, F.H.2    Kanaly, S.3
  • 38
    • 3242814586 scopus 로고    scopus 로고
    • Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
    • Huang W, Na L, Fidel PL, Schwarzenberger P. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis 2004;190(3):624-31
    • (2004) J Infect Dis , vol.190 , Issue.3 , pp. 624-631
    • Huang, W.1    Na, L.2    Fidel, P.L.3    Schwarzenberger, P.4
  • 39
    • 0242584872 scopus 로고    scopus 로고
    • Cutting edge: Roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection
    • Happel KI, Zheng M, Young E, et al. Cutting edge: Roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J Immunol 2003;170(9):4432-6
    • (2003) J Immunol , vol.170 , Issue.9 , pp. 4432-4436
    • Happel, K.I.1    Zheng, M.2    Young, E.3
  • 40
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D, Cheung J, Scheerens H, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006;116:1310-16
    • (2006) J Clin Invest , vol.116 , pp. 1310-1316
    • Yen, D.1    Cheung, J.2    Scheerens, H.3
  • 41
    • 79953073305 scopus 로고    scopus 로고
    • Anti-il-17a therapy protects against bone erosion in experimental models of rheumatoid arthritis
    • Chao CC, Chen SJ, Adamopoulos IE, et al. Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis. Autoimmunity 2011;44(3):243-52
    • (2011) Autoimmunity , vol.44 , Issue.3 , pp. 243-252
    • Chao, C.C.1    Chen, S.J.2    Adamopoulos, I.E.3
  • 42
    • 33745321276 scopus 로고    scopus 로고
    • IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
    • Komiyama Y, Nakae S, Matsuki T, et al. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 2006;177(1):566-73
    • (2006) J Immunol , vol.177 , Issue.1 , pp. 566-573
    • Komiyama, Y.1    Nakae, S.2    Matsuki, T.3
  • 43
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua DJ, Sherlock J, Chen Y, et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003;421(6924):744-8
    • (2003) Nature , vol.421 , Issue.6924 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3
  • 44
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005;201(2):233-40
    • (2005) J Exp Med , vol.201 , Issue.2 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 45
    • 33847279025 scopus 로고    scopus 로고
    • Pathogenesis and therapy of psoriasis
    • Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature 2007;445(7130):866-73
    • (2007) Nature , vol.445 , Issue.7130 , pp. 866-873
    • Lowes, M.A.1    Bowcock, A.M.2    Krueger, J.G.3
  • 46
    • 84862860846 scopus 로고    scopus 로고
    • IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis
    • Krueger JG, Fretzin S, Suárez-Fariñas M, et al. IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis. J Allergy Clin Immunol 2012;130(1):145-54
    • (2012) J Allergy Clin Immunol , vol.130 , Issue.1 , pp. 145-154
    • Krueger, J.G.1    Fretzin, S.2    Suárez-Fariñas, M.3
  • 47
    • 36448931232 scopus 로고    scopus 로고
    • IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats
    • Yago T, Nanke Y, Kawamoto M, et al. IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats. Arthritis Res Ther 2007;9:R96
    • (2007) Arthritis Res Ther , vol.9
    • Yago, T.1    Nanke, Y.2    Kawamoto, M.3
  • 48
    • 43249083380 scopus 로고    scopus 로고
    • A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci
    • Liu Y, Helms C, Liao W, et al. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet 2008;4:e1000041
    • (2008) PLoS Genet , vol.4
    • Liu, Y.1    Helms, C.2    Liao, W.3
  • 49
    • 84875216274 scopus 로고    scopus 로고
    • CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-g, IL-13, IL-17, and IL-22
    • Hijnen D, Knol EF, Gent YY, et al. CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-g, IL-13, IL-17, and IL-22. J Invest Dermatol 2013;133(4):973-9
    • (2013) J Invest Dermatol , vol.133 , Issue.4 , pp. 973-979
    • Hijnen, D.1    Knol, E.F.2    Gent, Y.Y.3
  • 50
    • 0036145337 scopus 로고    scopus 로고
    • The immunologic basis for the treatment of psoriasis with new biologic agents
    • Krueger JG. The immunologic basis for the treatment of psoriasis with new biologic agents. J Am Acad Dermatol 2002;46:1-23
    • (2002) J Am Acad Dermatol , vol.46 , pp. 1-23
    • Krueger, J.G.1
  • 51
    • 36048944693 scopus 로고    scopus 로고
    • Resident skin cells in psoriasis: A special look at the pathogenetic functions of keratinocytes
    • Albanesi C, De Pita O, Girolomoni G. Resident skin cells in psoriasis: A special look at the pathogenetic functions of keratinocytes. Clin Dermatol 2007;25:581-8
    • (2007) Clin Dermatol , vol.25 , pp. 581-588
    • Albanesi, C.1    De Pita, O.2    Girolomoni, G.3
  • 53
    • 30044435436 scopus 로고    scopus 로고
    • Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
    • Lowes MA, Chamian F, Abello MV, et al. Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). Proc Natl Acad Sci USA 2005;102:19057-62
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 19057-19062
    • Lowes, M.A.1    Chamian, F.2    Abello, M.V.3
  • 54
    • 58549114666 scopus 로고    scopus 로고
    • Resident and "inflammatory" dendritic cells in human skin
    • Zaba LC, Krueger JG, Lowes MA. Resident and "inflammatory" dendritic cells in human skin. J Invest Dermatol 2009;129:302-8
    • (2009) J Invest Dermatol , vol.129 , pp. 302-308
    • Zaba, L.C.1    Krueger, J.G.2    Lowes, M.A.3
  • 55
    • 0028245467 scopus 로고
    • Characterization of dermal dendritic cells in psoriasis: Autostimulation of T lymphocytes and induction of Th1 type cytokines
    • Nestle FO, Turka LA, Nickoloff BJ. Characterization of dermal dendritic cells in psoriasis: Autostimulation of T lymphocytes and induction of Th1 type cytokines. J Clin Invest 1994;94:202-9
    • (1994) J Clin Invest , vol.94 , pp. 202-209
    • Nestle, F.O.1    Turka, L.A.2    Nickoloff, B.J.3
  • 57
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal S, Ghilardi N, Xie MH, et al. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003;278:1910-14
    • (2003) J Biol Chem , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3
  • 58
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000;13(5):715-25
    • (2000) Immunity , vol.13 , Issue.5 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 59
    • 79951512605 scopus 로고    scopus 로고
    • Integrative responses to IL-17 and TNF-a in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis
    • Chiricozzi A, Guttman-Yassky E, Suárez-Fariñas M, et al. Integrative responses to IL-17 and TNF-a in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis. J Invest Dermatol 2011;131(3):677-87
    • (2011) J Invest Dermatol , vol.131 , Issue.3 , pp. 677-687
    • Chiricozzi, A.1    Guttman-Yassky, E.2    Suárez-Fariñas, M.3
  • 60
    • 54249130813 scopus 로고    scopus 로고
    • Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
    • Nograles KE, Zaba LC, Guttman-Yassky E, et al. Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br J Dermatol 2008;159:1086-91
    • (2008) Br J Dermatol , vol.159 , pp. 1086-1091
    • Nograles, K.E.1    Zaba, L.C.2    Guttman-Yassky, E.3
  • 61
    • 0027980960 scopus 로고
    • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
    • Detmar M, Brown LF, Claffey KP, et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 1994;180:1141-6
    • (1994) J Exp Med , vol.180 , pp. 1141-1146
    • Detmar, M.1    Brown, L.F.2    Claffey, K.P.3
  • 62
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
    • Manetti R, Parronchi P, Giudizi MG, et al. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med 1993;177(4):1199-204
    • (1993) J Exp Med , vol.177 , Issue.4 , pp. 1199-1204
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3
  • 63
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008;9(6):641-9
    • (2008) Nat Immunol , vol.9 , Issue.6 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 64
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of T(H)17 cells
    • Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of T(H)17 cells. Nature 2008;453(7198):1051-7
    • (2008) Nature , vol.453 , Issue.7198 , pp. 1051-1057
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 65
    • 47549112840 scopus 로고    scopus 로고
    • IL-21 and TGF-beta are required for differentiation of human T(H) 17 cells
    • Yang L, Anderson DE, Baecher-Allan C, et al. IL-21 and TGF-beta are required for differentiation of human T(H) 17 cells. Nature 2008;454(7202):350-2
    • (2008) Nature , vol.454 , Issue.7202 , pp. 350-352
    • Yang, L.1    Anderson, D.E.2    Baecher-Allan, C.3
  • 66
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen T, Geiger R, Jarrossay D, et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009;10:857-63
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3
  • 67
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T H)1 and T(H)2 cells
    • Trifari S, Kaplan CD, Tran EH, et al. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol 2009;10:864-71
    • (2009) Nat Immunol , vol.10 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3
  • 68
    • 66949180111 scopus 로고    scopus 로고
    • IL-23 drives pathogenic IL-17-producing CD8+ T cells
    • Ciric B, El-behi M, Cabrera R, et al. IL-23 drives pathogenic IL-17-producing CD8+ T cells. J Immunol 2009;182:5296-305
    • (2009) J Immunol , vol.182 , pp. 5296-5305
    • Ciric, B.1    El-behi, M.2    Cabrera, R.3
  • 69
    • 69249092613 scopus 로고    scopus 로고
    • A Th17-like developmental process leads to CD8+ Tc17 cells with reduced cytotoxic activity
    • Huber M, Heink S, Grothe H, et al. A Th17-like developmental process leads to CD8+ Tc17 cells with reduced cytotoxic activity. Eur J Immunol 2009;39:1716-25
    • (2009) Eur J Immunol , vol.39 , pp. 1716-1725
    • Huber, M.1    Heink, S.2    Grothe, H.3
  • 70
    • 80755180843 scopus 로고    scopus 로고
    • Pivotal role of dermal il-17-producing gd t cells in skin inflammation
    • Cai Y, Shen X, Ding C, et al. Pivotal role of dermal IL-17-producing gd T cells in skin inflammation. Immunity 2011;35(4):596-610
    • (2011) Immunity , vol.35 , Issue.4 , pp. 596-610
    • Cai, Y.1    Shen, X.2    Ding, C.3
  • 71
    • 58149331211 scopus 로고    scopus 로고
    • Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells
    • Zaba LC, Fuentes-Duculan J, Eungdamrong NJ, et al. Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. J Invest Dermatol 2009;129:79-88
    • (2009) J Invest Dermatol , vol.129 , pp. 79-88
    • Zaba, L.C.1    Fuentes-Duculan, J.2    Eungdamrong, N.J.3
  • 72
    • 78649666553 scopus 로고    scopus 로고
    • Overrepresentation of il-17a and il-22 producing cd8 t cells in lesional skin suggests their involvement in the pathogenesis of psoriasis
    • Res PC, Piskin G, de Boer OJ, et al. Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS One 2010;5(11):e14108
    • (2010) PLoS One , vol.5 , Issue.11
    • Res, P.C.1    Piskin, G.2    De Boer, O.J.3
  • 73
    • 59149106117 scopus 로고    scopus 로고
    • Genome-wide scan reveals association of psoriasis with il-23 and nf-kappab pathways
    • Nair RP, Duffin KC, Helms C, et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet 2009;41:199-204
    • (2009) Nat Genet , vol.41 , pp. 199-204
    • Nair, R.P.1    Duffin, K.C.2    Helms, C.3
  • 74
    • 42149140747 scopus 로고    scopus 로고
    • Polymorphisms of the IL12B and IL23R genes are associated with psoriasis
    • Nair RP, Ruether A, Stuart PE, et al. Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J Invest Dermatol 2008;128:1653-61
    • (2008) J Invest Dermatol , vol.128 , pp. 1653-1661
    • Nair, R.P.1    Ruether, A.2    Stuart, P.E.3
  • 75
    • 13844292408 scopus 로고    scopus 로고
    • Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
    • Sigurdsson S, Nordmark G, Goring HH, et al. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 2005;76:528-37
    • (2005) Am J Hum Genet , vol.76 , pp. 528-537
    • Sigurdsson, S.1    Nordmark, G.2    Goring, H.H.3
  • 76
    • 78049347495 scopus 로고    scopus 로고
    • A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
    • Strange A, Capon F, Spencer CC, et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010;42:985-90
    • (2010) Nat Genet , vol.42 , pp. 985-990
    • Strange, A.1    Capon, F.2    Spencer, C.C.3
  • 77
    • 78049350350 scopus 로고    scopus 로고
    • Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
    • Huffmeier U, Uebe S, Ekici AB, et al. Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet 2010;42:996-9
    • (2010) Nat Genet , vol.42 , pp. 996-999
    • Huffmeier, U.1    Uebe, S.2    Ekici, A.B.3
  • 78
    • 37549033125 scopus 로고    scopus 로고
    • Psoriasis is associated with increased beta-defensin genomic copy number
    • Hollox EJ, Huffmeier U, Zeeuwen PL, et al. Psoriasis is associated with increased beta-defensin genomic copy number. Nat Genet 2008;40:23-5
    • (2008) Nat Genet , vol.40 , pp. 23-25
    • Hollox, E.J.1    Huffmeier, U.2    Zeeuwen, P.L.3
  • 79
    • 84872275425 scopus 로고    scopus 로고
    • The emerging role of IL-17 in the pathogenesis of psoriasis: Preclinical and clinical findings
    • Martin DA, Towne JE, Kricorian G, et al. The emerging role of IL-17 in the pathogenesis of psoriasis: Preclinical and clinical findings. J Invest Dermatol 2013;133(1):17-26
    • (2013) J Invest Dermatol , vol.133 , Issue.1 , pp. 17-26
    • Martin, D.A.1    Towne, J.E.2    Kricorian, G.3
  • 80
    • 33751546237 scopus 로고    scopus 로고
    • IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
    • Chan JR, Blumenschein W, Murphy E, et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med 2006;203(12):2577-87
    • (2006) J Exp Med , vol.203 , Issue.12 , pp. 2577-2587
    • Chan, J.R.1    Blumenschein, W.2    Murphy, E.3
  • 81
    • 79251569587 scopus 로고    scopus 로고
    • IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A
    • Rizzo HL, Kagami S, Phillips KG, et al. IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A. J Immunol 2011;186(3):1495-502
    • (2011) J Immunol , vol.186 , Issue.3 , pp. 1495-1502
    • Rizzo, H.L.1    Kagami, S.2    Phillips, K.G.3
  • 82
    • 31144441631 scopus 로고    scopus 로고
    • In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: Enhanced expression in psoriatic skin
    • Piskin G, Sylva-Steenland RM, Bos JD, Teunissen MB. In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: Enhanced expression in psoriatic skin. J Immunol 2006;176(3):1908-15
    • (2006) J Immunol , vol.176 , Issue.3 , pp. 1908-1915
    • Piskin, G.1    Sylva-Steenland, R.M.2    Bos, J.D.3    Teunissen, M.B.4
  • 83
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • Lee E, Trepicchio WL, Oestreicher JL, et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 2004;199(1):125-30
    • (2004) J Exp Med , vol.199 , Issue.1 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3
  • 84
    • 71749085498 scopus 로고    scopus 로고
    • Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes
    • Zaba LC, Suárez-Fariñas M, Fuentes-Duculan J, et al. Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes. J Allergy Clin Immunol 2009;124(5):1022-10
    • (2009) J Allergy Clin Immunol , vol.124 , Issue.5 , pp. 1022-10
    • Zaba, L.C.1    Suárez-Fariñas, M.2    Fuentes-Duculan, J.3
  • 85
    • 77957952423 scopus 로고    scopus 로고
    • Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques
    • Johnson-Huang LM, Suárez-Fariñas M, Sullivan-Whalen M, et al. Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques. J Invest Dermatol 2010;130(11):2654-63
    • (2010) J Invest Dermatol , vol.130 , Issue.11 , pp. 2654-2663
    • Johnson-Huang, L.M.1    Suárez-Fariñas, M.2    Sullivan-Whalen, M.3
  • 86
    • 37549011317 scopus 로고    scopus 로고
    • Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
    • Zaba LC, Cardinale I, Gilleaudeau P, et al. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med 2007;204:3183-94
    • (2007) J Exp Med , vol.204 , pp. 3183-3194
    • Zaba, L.C.1    Cardinale, I.2    Gilleaudeau, P.3
  • 87
    • 40749156754 scopus 로고    scopus 로고
    • Identification of cellular pathways of type 1, th17 t cells, and tnf- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine a in psoriasis
    • Haider AS, Lowes MA, Suarez-Farinas M, et al. Identification of cellular pathways of "Type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis. J Immunol 2008;180:1913-20
    • (2008) J Immunol , vol.180 , pp. 1913-1920
    • Haider, A.S.1    Lowes, M.A.2    Suarez-Farinas, M.3
  • 88
    • 0034660183 scopus 로고    scopus 로고
    • Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis
    • Homey B, Dieu-Nosjean MC, Wiesenborn A, et al. Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis. J Immunol 2000;164:6621-32
    • (2000) J Immunol , vol.164 , pp. 6621-6632
    • Homey, B.1    Dieu-Nosjean, M.C.2    Wiesenborn, A.3
  • 89
    • 84859073115 scopus 로고    scopus 로고
    • Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
    • Available from
    • Leonardi C, Matheson R, Zachariae C, et al. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med 2012;366(13):1190-9 Available from: Http://www.clinicaltrials. gov/ct2/results?term=ixekizumab+AND +psoriasis&Search=Search
    • (2012) N Engl J Med , vol.366 , Issue.13 , pp. 1190-1199
    • Leonardi, C.1    Matheson, R.2    Zachariae, C.3
  • 90
    • 79951508449 scopus 로고    scopus 로고
    • Blockade of the IL-17R with AMG827 leads to rapid reversal of gene expression and histopathologic abnormalities in human psoriatic skin [abstract]
    • Russell CB, Kerkof K, Bigler J, et al. Blockade of the IL-17R with AMG827 leads to rapid reversal of gene expression and histopathologic abnormalities in human psoriatic skin [abstract]. J Invest Dermatol 2010;130:S46
    • (2010) J Invest Dermatol , vol.130
    • Russell, C.B.1    Kerkof, K.2    Bigler, J.3
  • 91
    • 84859017988 scopus 로고    scopus 로고
    • Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
    • Available from
    • Papp KA, Leonardi C, Menter A, et al. Brodalumab, an anti-interleukin-17- receptor antibody for psoriasis. N Engl J Med 2012;366(13):1181-9 Available from: Http://www.clinicaltrials. gov/ct2/results?term=brodalumab+AND +psoriasis&Search=Search
    • (2012) N Engl J Med , vol.366 , Issue.13 , pp. 1181-1189
    • Papp, K.A.1    Leonardi, C.2    Menter, A.3
  • 92
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • Hueber W, Patel DD, Dryja T, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2010;2(52):52ra72
    • (2010) Sci Transl Med , vol.2
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3
  • 93
    • 84873124241 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled phase II dose-ranging study
    • Papp KA, Langley RG, Sigurgeirsson B, et al. Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled phase II dose-ranging study. Br J Dermatol 2013;168(2):412-21
    • (2013) Br J Dermatol , vol.168 , Issue.2 , pp. 412-421
    • Papp, K.A.1    Langley, R.G.2    Sigurgeirsson, B.3
  • 94
    • 84873126666 scopus 로고    scopus 로고
    • Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: A randomised, double-blind, placebo-controlled, phase II regimen-finding study
    • Epub ahead of print]
    • Rich P, Sigurgeirsson B, Thaci DP, et al. Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: A randomised, double-blind, placebo-controlled, phase II regimen-finding study. Br J Dermatol 2012; [Epub ahead of print]
    • (2012) Br J Dermatol
    • Rich, P.1    Sigurgeirsson, B.2    Thaci, D.P.3
  • 95
    • 84891740105 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab a fully human anti-interleukin-17a monoclonal antibody in patients with moderate-to-severe psoriatic arthritis: A 24-week randomised double-blind placebo-controlled phase ii proof-of-concept trial
    • Epub ahead of print] Available from
    • McInnes IB, Sieper J, Braun J, et al. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: A 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann Rheum Dis 2013; [Epub ahead of print] Available from: Http://www.clinicaltrials. gov/ct2/results?term= secukinumab+ AND+psoriasis
    • (2013) Ann Rheum Dis
    • McInnes, I.B.1    Sieper, J.2    Braun, J.3
  • 96
    • 84875433817 scopus 로고    scopus 로고
    • Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: Final results from 5 years of follow-up
    • Papp KA, Griffiths CE, Gordon K. Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: Final results from 5 years of follow-up. Br J Dermatol 2013;168(4):844-54
    • (2013) Br J Dermatol , vol.168 , Issue.4 , pp. 844-854
    • Papp, K.A.1    Griffiths, C.E.2    Gordon, K.3
  • 97
    • 84870956525 scopus 로고    scopus 로고
    • Hiding under the skin: A welcome surprise in psoriasis
    • Krueger JG. Hiding under the skin: A welcome surprise in psoriasis. Nat Med 2012;18(12):1750-1
    • (2012) Nat Med , vol.18 , Issue.12 , pp. 1750-1751
    • Krueger, J.G.1
  • 98
    • 77954062300 scopus 로고    scopus 로고
    • Emerging role of IL-17 in atherosclerosis
    • Chen S, Crother TR, Arditi M. Emerging role of IL-17 in atherosclerosis. J Innate Immun 2010;2(4):325-33
    • (2010) J Innate Immun , vol.2 , Issue.4 , pp. 325-33
    • Chen, S.1    Crother, T.R.2    Arditi, M.3
  • 99
    • 37249004404 scopus 로고    scopus 로고
    • The risk of mortality in patients with psoriasis: Results from a population-based study
    • Gelfand JM, Troxel AB, Lewis JD, et al. The risk of mortality in patients with psoriasis: Results from a population-based study. Arch Dermatol 2007;143(12):1493-9
    • (2007) Arch Dermatol , vol.143 , Issue.12 , pp. 1493-1499
    • Gelfand, J.M.1    Troxel, A.B.2    Lewis, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.