Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

Frontiers in Physiology

Volumn 6, Issue JUN, 2015, Pages

  Aldunate, Muriel ^a,b   Srbinovski, Daniela ^a,b   Hearps, Anna C ^a,b   Latham, Catherine F ^a   Ramsland, Paul A ^a,b,c,d   Gugasyan, Raffi ^a,b   Cone, Richard A ^e   Tachedjian, Gilda ^a,b,c  

^a BURNET INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d CURTIN UNIVERSITY   (Australia)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bacterial vaginosis; Lactic acid; Lactobacilli; Metabolites; Microbiome; Short chain fatty acids; Vaginal microbiota

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CLINDAMYCIN; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LACTIC ACID; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; METRONIDAZOLE; MICROBICIDE; PROPIONIC ACID; RANTES; SHORT CHAIN FATTY ACID; SUCCINIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ACIDIFICATION; AMSEL CRITERIA; ANAEROBIC BACTERIUM; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC THERAPY; ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; BACTERIAL INFECTION; CLINICAL ASSESSMENT TOOL; COMMUNITY DYNAMICS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIAGNOSTIC TEST; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE PREDISPOSITION; ENDOSYMBIOSIS; FEMALE; FEMALE GENITAL SYSTEM; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; INTERMETHOD COMPARISON; METABOLITE; METABOLOME; NONHUMAN; NUGENT SCORE; OUTCOME ASSESSMENT; PELVIC INFLAMMATORY DISEASE; PREMATURITY; RECURRENT DISEASE; REPRODUCTIVE HEALTH; REVIEW; SEXUALLY TRANSMITTED DISEASE; SPONTANEOUS ABORTION; VAGINA DISCHARGE; VAGINA FLORA; VAGINA MUCOSA; VAGINA PH; VAGINITIS;

EID: 84940031828     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2015.00164     Document Type: Review

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