Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

PLoS Pathogens

Volumn 6, Issue 4, 2010, Pages 1-20

  Nazli, Aisha ^a   Chan, Olivia ^a   Dobson Belaire, Wendy N ^b   Ouellet, Michel ^c   Tremblay, Michel J ^c   Gray Owen, Scott D ^b   Arsenault, A Larry ^a   Kaushic, Charu ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 1; CLAUDIN 2; CLAUDIN 4; OCCLUDIN; PROTEIN ZO1; TUMOR NECROSIS FACTOR ALPHA; GLYCOPROTEIN GP 120;

ADULT; ARTICLE; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; DENSITOMETRY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; FEMALE; GENE DISRUPTION; GENE SEQUENCE; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; MUCOSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PURIFICATION; UPREGULATION; VIRUS CELL INTERACTION; VIRUS NEUTRALIZATION; VIRUS TRANSMISSION; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MIDDLE AGED; PATHOGENICITY; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIGHT JUNCTION; VIROLOGY;

BACTERIA (MICROORGANISMS); HUMAN IMMUNODEFICIENCY VIRUS 1;

ADULT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MIDDLE AGED; MUCOUS MEMBRANE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIGHT JUNCTIONS;

EID: 77954059792     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000852     Document Type: Article

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