Bacterial vaginosis and disturbances of vaginal flora: Association with increased acquisition of HIV

AIDS

Volumn 12, Issue 13, 1998, Pages 1699-1706

  Taha, Taha E ^a   Hoover, Donald R ^a   Dallabetta, Gina A ^a,d   Kumwenda, Newton I ^a   Mtimavalye, Laban A R ^b   Yang, Li Ping ^a   Liomba, George N ^b   Broadhead, Robin L ^b   Chiphangwi, John D ^b   Miotti, Paolo G ^a,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF MALAWI   (Malawi)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d FAMILY HEALTH INTERNATIONAL   (United States)

Author keywords

Bacterial vaginosis; HIV incidence; Malawi; Seroconversion; Sexually transmitted diseases; Women

Indexed keywords

ADULT; ARTICLE; CLINICAL EXAMINATION; DELIVERY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFORMED CONSENT; LABORATORY TEST; MAJOR CLINICAL STUDY; MALAWI; PATIENT COUNSELING; PREGNANCY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUERPERIUM; REGRESSION ANALYSIS; SEROCONVERSION; SEXUALLY TRANSMITTED DISEASE; VAGINA FLORA; VAGINITIS; VIRUS LOAD;

COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; HIV INFECTIONS; HIV SEROPREVALENCE; HIV-1; HUMANS; LONGITUDINAL STUDIES; MALAWI; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RISK FACTORS; VAGINA; VAGINOSIS, BACTERIAL;

EID: 7344236840     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199813000-00019     Document Type: Article

References (36)

1. Sewankambo N, Gray RH, Wawer MJ, et al.: HIV-1 infection associated with abnormal vaginal flora morphology and bacterial vaginosis. Lancet 1997, 350:546-550.
2. Govender L, Hoosen AA, Moodely J, Moodley P, Sturm AW: Bacterial vaginosis and associated infections in pregnancy. Int J Gynecol Obstet 1996, 55:23-28.
3. Hillier SL: Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol 1993, 169:455-459.
4. Esthenbach DA, Davick PR, Williams BL, et al.: Prevalence of hydrogen peroxide-producing Lactobacillus species in normal women and women with bacterial vaginosis. J Clin Microbiol 1989, 27:251-256.
5. Paavonen J: Physiology and ecology of the vagina. Scand J Infect Dis 1983, 40(Suppl):31-35.
6. Hillier SL, Krohn MA, Nugent RP, Gibbs RS, the Vaginal Infections and Prematurity Study Group: Characteristics of three vaginal flora patterns assessed by Gram slain among pregnant women. Am J Obstet Gynecol 1992, 166:938-944.
7. Holmes KK, Chen KCS, Lipinski CM, Eschenbach DA: Vaginal redox potential in bacterial vaginosis (nonspecific vaginitis). J Infect Dis 1985, 152:379-382.
8. Hill JA, Anderson DJ: Human vaginal leukocytes and the effects of vaginal fluid on lymphocyte and macrophage defense functions. Am J Obstet Gynecol 1992, 166:720-726.
9. Voller B, Anderson DJ: Heterosexual transmission of HIV [Letter]. JAMA 1992, 267:1917-1918.
10. Amsel K, Totten PA, Spiegel CA, Chen KCS, Eschenbach D, Holmes KK: Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 1983, 74:14-22.
11. Nugent RP, Krohn MA, Hilliec SL: Reliability of diagnosing bacterial vaginosis is improved by a standardized method of Gram stain interpretation. J Clin Microbiol 1991, 29:297-301.
12. Kelsey JL, Thompson WD, Evans AS (Eds): Methods in Observational Epidemiology. New York: Oxford University Press 1986.
13. Hoover DR: Extension of the life table to repeating and changing events. Am J Epidemiol 1996, 143:1266-1276.
14. Eschenbach DA, Hillier S, Critchlow C, Stevens C, DeRouen T, Holmes KK: Diagnosis and clinical manifestations of bacterial vaginosis. Am J Obstet Gynecol 1988, 158:819-828.
15. Thomason JI, Andersom RJ, Gelbart SM, et al.: Simplified Gram stain interpretive method for diagnosis of bacterial vaginosis. Am J Obstet Gynecol 1992, 167:16-19.
16. Cohen CR, Duerr A, Pruithithada N, et al.: Bacterial vaginosis and HIV seroprevalence among female commercial sex workers in Chiang Mai, Thailand. AIDS 1995, 9:1093-1097.
17. Jaha TE, Miotti P, Dallabetta G, Liomba G, Kumwenda N, Chiphnagwi J: Bacterial vaginosis during pregnancy: Associations with HIV, preterm delivery, and mother-to-child transmission of HIV. Conference on Global Stategies for the Prevntion of HIV Ttansmission from Mothers to Infants, September 1997. Washington, DC. [abstract].
18. Taha TL, Dallabetta GA, Hoover DR, et al.: Trends of HIV-1 and sexually transmitted diseases among pregnant and postpartum women in urban Malawi. AIDS 1998, 12:197-203.
19. Miotti P, Ganner J, Chiphangwi J, Liomba G, Saah A, Dallabetta G: Rate of new HIV infection in a cohort of women of child-bearing age in Malawi. AIDS Res Human Retrovir 1994, 10(Suppl 2):S239-S2421.
20. Vejtorp M, Bollerup AC, Vejtorp L, et al.: Bacterial vaginosis: a double-blind randomized trial of the effect of treatment of sexual partner. Br J Obstet Gynaecol 1988, 95:920-926.
21. Moi H, Erkkola R, jerve F, et al.: Should male consorts of women with bacterial vaginosis be treated. Genitourin Med 1989, 65:263-268.
22. Laha TET, Canner JK, Chiphangwi JD, et al.: Reported condom use is not associated with incidence of sexually transmitted diseases in Malawi. AIDS 1996, 10:207-212.
23. Cohen MS, Hoffman IF, Royce RA, et al.: Reduction of concentration of HIV-1 in semen after treatment of urethrilis: implications for prevention of sexual transmission of HIV-1. Lancet 1997, 349:1868-1873.
24. Dallabetta G, Diomi MC: Treating STDs to control HIV transmission. Curr Opin Inf Dis 1997, 10:22-25.
25. Wasserheit JN: Epidemiological synergy: Interrelationship between human immunodeficiency virus infection and other sexually transmitted diseases. Sex Transm Dis 1992, 19:61-77.
26. Laga M, Diallo MO, Buve A: Inter-relationship of sexually transmitted diseases and HIV: where are we now? AIDS 1994, 8(Suppl 1):S119-S124.
27. Quinn IC: Association of sexually transmitted diseases and infection with the human immunodeficiency virus: biological co-factors and markers of behavioral interventions. Int J SID and AIDS 1996, 7(Suppl 2): 17-24.
28. Grosskurth H, Mosha F, Todd J, et al.: Impact of improved treatment of sexually transmitted diseases on HIV infection in rural Tanzania: randomized controlled trial. Lancet 1995, 346:530-536.
29. Hillier SL, Krohn MA, Klebanoff SJ, Eschenbach DA: The relationship of hydrogen peroxide-producing lactobacilli to bacterial vaginosis and genital microflora in pregnant women. Obstet Gynecol 1992, 79:369-373.
30. Klebanoff SJ, Coobs RW: Viricidal effect of lactobacillus acidophilus on human immunodeficiency virus type 1: possible role in heterosexual transmission. J Exp Med 1991, 174:289-292.
31. Mardh P-A: The vaginal ecosystem. Am J Obstet Gynecol 1991, 165:1163-1168.
32. Spiegel CA, Amsel K, Holmes KK: Diagnosis of bacterial vaginosis by direct Gram stain of vaginal fluid. J Clin Microbiol 1983, 18:170-177.
33. Mostad SB, Kreiss JK: Shedding of HIV-1 in the genital tract. AIDS 1996, 10:1305-1315.
34. Hillier SL, Nugent RP, Eschenbach DA, et al.: Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. N Engl J Med 1995, 333:1737-1742.
35. Hauth JC, Goldenberg RL, Andrews WW, DuBard MB, Copper RL: Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis. N Engl J Med 1995, 333:1732-1736.
36. McGregor JA, French JI, Poarker R, et al.: Prevention of premature birth by screening and treatment for common genital tract infections: results of a prospective controlled evaluation. Am J Obstet Gynecol 1995, 173:157-167.