메뉴 건너뛰기




Volumn 65, Issue 3, 2011, Pages 253-260

HIV-1 Infection in the Female Reproductive Tract: Role of Interactions between HIV-1 and Genital Epithelial Cells

Author keywords

Cytokines; Epithelial cells; Female genital tract; HIV 1; HIV 1 transmission

Indexed keywords

CYTOKINE;

EID: 79551646881     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2010.00965.x     Document Type: Review
Times cited : (55)

References (63)
  • 1
    • 44349159423 scopus 로고    scopus 로고
    • Setting the stage: host invasion by HIV
    • Hladik F, McElrath MJ: Setting the stage: host invasion by HIV. Nat Rev Immunol 2008; 8:447-457.
    • (2008) Nat Rev Immunol , vol.8 , pp. 447-457
    • Hladik, F.1    McElrath, M.J.2
  • 2
    • 79551641074 scopus 로고    scopus 로고
    • UNAIDS: UNAIDS Report on AIDS Epidemic -July 2008.
    • UNAIDS: UNAIDS Report on AIDS Epidemic -July 2008. 2008.
    • (2008)
  • 3
    • 61449159825 scopus 로고    scopus 로고
    • HIV infection of the genital mucosa in women
    • Hladik F, Hope TJ: HIV infection of the genital mucosa in women. Curr HIV/AIDS Rep 2009; 6:20-28.
    • (2009) Curr HIV/AIDS Rep , vol.6 , pp. 20-28
    • Hladik, F.1    Hope, T.J.2
  • 4
    • 77949409948 scopus 로고    scopus 로고
    • Targeting early infection to prevent HIV-1 mucosal transmission
    • Haase AT: Targeting early infection to prevent HIV-1 mucosal transmission. Nature 2010; 464:217-223.
    • (2010) Nature , vol.464 , pp. 217-223
    • Haase, A.T.1
  • 8
    • 36048945481 scopus 로고    scopus 로고
    • The interaction of HIV with dendritic cells: outcomes and pathways
    • Piguet V, Steinman RM: The interaction of HIV with dendritic cells: outcomes and pathways. Trends Immunol 2007; 28:503-510.
    • (2007) Trends Immunol , vol.28 , pp. 503-510
    • Piguet, V.1    Steinman, R.M.2
  • 10
    • 0037423819 scopus 로고    scopus 로고
    • Recent observations on HIV type-1 infection in the genital tract of men and women
    • Coombs RW, Reichelderfer PS, Landay AL: Recent observations on HIV type-1 infection in the genital tract of men and women. AIDS 2003; 17:455-480.
    • (2003) AIDS , vol.17 , pp. 455-480
    • Coombs, R.W.1    Reichelderfer, P.S.2    Landay, A.L.3
  • 11
    • 0021355701 scopus 로고
    • Investigation of microtrauma after sexual intercourse
    • Norvell MK, Benrubi GI, Thompson RJ: Investigation of microtrauma after sexual intercourse. J Reprod Med 1984; 29:269-271.
    • (1984) J Reprod Med , vol.29 , pp. 269-271
    • Norvell, M.K.1    Benrubi, G.I.2    Thompson, R.J.3
  • 12
    • 1842327432 scopus 로고    scopus 로고
    • Postcoital vaginal bleeding as a risk factor for transmission of the human immunodeficiency virus in a heterosexual partner study in Brazil. Rio de Janeiro Heterosexual Study Group
    • Guimaraes MD, Vlahov D, Castilho EA: Postcoital vaginal bleeding as a risk factor for transmission of the human immunodeficiency virus in a heterosexual partner study in Brazil. Rio de Janeiro Heterosexual Study Group. Arch Intern Med 1997; 157:1362-1368.
    • (1997) Arch Intern Med , vol.157 , pp. 1362-1368
    • Guimaraes, M.D.1    Vlahov, D.2    Castilho, E.A.3
  • 13
    • 0001895017 scopus 로고    scopus 로고
    • Sexually Transmitted Diseases
    • In 3rd edn, KK Holmes, PF Sparling, PA Mardh, SM Lemon, WE Stamm, P Piot, JN Wasserheit (eds). New York, McGraw-Hill
    • Hillier SL: Normal vaginal flora. In Sexually Transmitted Diseases 3rd edn, KK Holmes, PF Sparling, PA Mardh, SM Lemon, WE Stamm, P Piot, JN Wasserheit (eds). New York, McGraw-Hill, 1999, pp 191-204.
    • (1999) Normal vaginal flora , pp. 191-204
    • Hillier, S.L.1
  • 14
    • 77953920807 scopus 로고    scopus 로고
    • Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens
    • Wira CR, Fahey JV, Ghosh M, Patel MV, Hickey DK, Ochiel DO: Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens. Am J Reprod Immunol 2010; 63:544-565.
    • (2010) Am J Reprod Immunol , vol.63 , pp. 544-565
    • Wira, C.R.1    Fahey, J.V.2    Ghosh, M.3    Patel, M.V.4    Hickey, D.K.5    Ochiel, D.O.6
  • 15
    • 28144449069 scopus 로고    scopus 로고
    • Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone
    • Pudney J, Quayle AJ, Anderson DJ: Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone. Biol Reprod 2005; 73:1253-1263.
    • (2005) Biol Reprod , vol.73 , pp. 1253-1263
    • Pudney, J.1    Quayle, A.J.2    Anderson, D.J.3
  • 18
    • 0029115952 scopus 로고
    • Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro
    • McNeely TB, Dealy M, Dripps DJ, Orenstein JM, Eisenberg SP, Wahl SM: Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro. J Clin Invest 1995; 96:456-464.
    • (1995) J Clin Invest , vol.96 , pp. 456-464
    • McNeely, T.B.1    Dealy, M.2    Dripps, D.J.3    Orenstein, J.M.4    Eisenberg, S.P.5    Wahl, S.M.6
  • 19
    • 0030741731 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription
    • McNeely TB, Shugars DC, Rosendahl M, Tucker C, Eisenberg SP, Wahl SM: Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription. Blood 1997; 90:1141-1149.
    • (1997) Blood , vol.90 , pp. 1141-1149
    • McNeely, T.B.1    Shugars, D.C.2    Rosendahl, M.3    Tucker, C.4    Eisenberg, S.P.5    Wahl, S.M.6
  • 20
    • 0029080953 scopus 로고
    • Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro
    • Harmsen MC, Swart PJ, de Bethune MP, Pauwels R, De Clercq E, The TH, Meijer DK: Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J Infect Dis 1995; 172:380-388.
    • (1995) J Infect Dis , vol.172 , pp. 380-388
    • Harmsen, M.C.1    Swart, P.J.2    de Bethune, M.P.3    Pauwels, R.4    De Clercq, E.5    The, T.H.6    Meijer, D.K.7
  • 21
    • 0035869444 scopus 로고    scopus 로고
    • A milk protein lactoferrin enhances human T cell leukemia virus type I and suppresses HIV-1 infection
    • Moriuchi M, Moriuchi H: A milk protein lactoferrin enhances human T cell leukemia virus type I and suppresses HIV-1 infection. J Immunol 2001; 166:4231-4236.
    • (2001) J Immunol , vol.166 , pp. 4231-4236
    • Moriuchi, M.1    Moriuchi, H.2
  • 23
    • 33745698864 scopus 로고    scopus 로고
    • Defensins in innate antiviral immunity
    • Klotman ME, Chang TL: Defensins in innate antiviral immunity. Nat Rev Immunol 2006; 6:447-456.
    • (2006) Nat Rev Immunol , vol.6 , pp. 447-456
    • Klotman, M.E.1    Chang, T.L.2
  • 24
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: antimicrobial peptides of innate immunity
    • Ganz T: Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol 2003; 3:710-720.
    • (2003) Nat Rev Immunol , vol.3 , pp. 710-720
    • Ganz, T.1
  • 29
    • 73949143527 scopus 로고    scopus 로고
    • Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract
    • Ghosh M, Shen Z, Fahey JV, Cu-Uvin S, Mayer K, Wira CR: Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract. Immunology 2010; 129:207-219.
    • (2010) Immunology , vol.129 , pp. 207-219
    • Ghosh, M.1    Shen, Z.2    Fahey, J.V.3    Cu-Uvin, S.4    Mayer, K.5    Wira, C.R.6
  • 30
    • 14644404417 scopus 로고    scopus 로고
    • Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection
    • Wira CR, Grant-Tschudy KS, Crane-Godreau MA: Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection. Am J Reprod Immunol 2005; 53:65-76.
    • (2005) Am J Reprod Immunol , vol.53 , pp. 65-76
    • Wira, C.R.1    Grant-Tschudy, K.S.2    Crane-Godreau, M.A.3
  • 31
    • 20744444590 scopus 로고    scopus 로고
    • Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract
    • Fahey JV, Schaefer TM, Channon JY, Wira CR: Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract. Hum Reprod 2005; 20:1439-1446.
    • (2005) Hum Reprod , vol.20 , pp. 1439-1446
    • Fahey, J.V.1    Schaefer, T.M.2    Channon, J.Y.3    Wira, C.R.4
  • 32
    • 3042789092 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells
    • Schaefer TM, Desouza K, Fahey JV, Beagley KW, Wira CR: Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells. Immunology 2004; 112:428-436.
    • (2004) Immunology , vol.112 , pp. 428-436
    • Schaefer, T.M.1    Desouza, K.2    Fahey, J.V.3    Beagley, K.W.4    Wira, C.R.5
  • 33
    • 0036499128 scopus 로고    scopus 로고
    • Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like Receptor 4- mediated signaling
    • Fichorova RN, Cronin AO, Lien E, Anderson DJ, Ingalls RR: Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like Receptor 4- mediated signaling. J Immunol 2002; 168:2424-2432.
    • (2002) J Immunol , vol.168 , pp. 2424-2432
    • Fichorova, R.N.1    Cronin, A.O.2    Lien, E.3    Anderson, D.J.4    Ingalls, R.R.5
  • 34
    • 33645999981 scopus 로고    scopus 로고
    • Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens
    • Andersen JM, Al-Khairy D, Ingalls RR: Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens. Biol Reprod 2006; 74:824-831.
    • (2006) Biol Reprod , vol.74 , pp. 824-831
    • Andersen, J.M.1    Al-Khairy, D.2    Ingalls, R.R.3
  • 35
    • 39149137535 scopus 로고    scopus 로고
    • Quantification and comparison of toll-like receptor expression and responsiveness in primary and immortalized human female lower genital tract epithelia
    • Herbst-Kralovetz MM, Quayle AJ, Ficarra M, Greene S, Rose WA II, Chesson R, Spagnuolo RA, Pyles RB: Quantification and comparison of toll-like receptor expression and responsiveness in primary and immortalized human female lower genital tract epithelia. Am J Reprod Immunol 2008; 59:212-224.
    • (2008) Am J Reprod Immunol , vol.59 , pp. 212-224
    • Herbst-Kralovetz, M.M.1    Quayle, A.J.2    Ficarra, M.3    Greene, S.4    Rose II, W.A.5    Chesson, R.6    Spagnuolo, R.A.7    Pyles, R.B.8
  • 36
    • 58249086367 scopus 로고    scopus 로고
    • Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women
    • Nazli A, Yao XD, Smieja M, Rosenthal KL, Ashkar AA, Kaushic C: Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women. Antiviral Res 2009; 81:103-112.
    • (2009) Antiviral Res , vol.81 , pp. 103-112
    • Nazli, A.1    Yao, X.D.2    Smieja, M.3    Rosenthal, K.L.4    Ashkar, A.A.5    Kaushic, C.6
  • 37
    • 38849196295 scopus 로고    scopus 로고
    • Differential inhibition of human cytomegalovirus (HCMV) by toll-like receptor ligands mediated by interferon-beta in human foreskin fibroblasts and cervical tissue
    • Harwani SC, Lurain NS, Zariffard MR, Spear GT: Differential inhibition of human cytomegalovirus (HCMV) by toll-like receptor ligands mediated by interferon-beta in human foreskin fibroblasts and cervical tissue. Virol J 2007; 4:133.
    • (2007) Virol J , vol.4 , pp. 133
    • Harwani, S.C.1    Lurain, N.S.2    Zariffard, M.R.3    Spear, G.T.4
  • 38
    • 33746190700 scopus 로고    scopus 로고
    • Alpha interferon potently enhances the anti-human immunodeficiency virus type 1 activity of APOBEC3G in resting primary CD4 T cells
    • Chen K, Huang J, Zhang C, Huang S, Nunnari G, Wang FX, Tong X, Gao L, Nikisher K, Zhang H: Alpha interferon potently enhances the anti-human immunodeficiency virus type 1 activity of APOBEC3G in resting primary CD4 T cells. J Virol 2006; 80:7645-7657.
    • (2006) J Virol , vol.80 , pp. 7645-7657
    • Chen, K.1    Huang, J.2    Zhang, C.3    Huang, S.4    Nunnari, G.5    Wang, F.X.6    Tong, X.7    Gao, L.8    Nikisher, K.9    Zhang, H.10
  • 39
    • 0034141939 scopus 로고    scopus 로고
    • Retrovirally mediated IFN-beta transduction of macrophages induces resistance to HIV, correlated with up-regulation of RANTES production and down-regulation of C-C chemokine receptor-5 expression
    • Cremer I, Vieillard V, De Maeyer E: Retrovirally mediated IFN-beta transduction of macrophages induces resistance to HIV, correlated with up-regulation of RANTES production and down-regulation of C-C chemokine receptor-5 expression. J Immunol 2000; 164:1582-1587.
    • (2000) J Immunol , vol.164 , pp. 1582-1587
    • Cremer, I.1    Vieillard, V.2    De Maeyer, E.3
  • 40
    • 0027510449 scopus 로고
    • Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action
    • Zhou A, Hassel BA, Silverman RH: Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action. Cell 1993; 72:753-765.
    • (1993) Cell , vol.72 , pp. 753-765
    • Zhou, A.1    Hassel, B.A.2    Silverman, R.H.3
  • 41
    • 0017948303 scopus 로고
    • Inhibition of cell-free protein synthesis by pppA2'p5'A2'p5'A: a novel oligonucleotide synthesized by interferon-treated L cell extracts
    • Clemens MJ, Williams BR: Inhibition of cell-free protein synthesis by pppA2'p5'A2'p5'A: a novel oligonucleotide synthesized by interferon-treated L cell extracts. Cell 1978; 13:565-572.
    • (1978) Cell , vol.13 , pp. 565-572
    • Clemens, M.J.1    Williams, B.R.2
  • 44
    • 0035905645 scopus 로고    scopus 로고
    • Endogenous and exogenous interferons in HIV-infection
    • Karpov AV: Endogenous and exogenous interferons in HIV-infection. Eur J Med Res 2001; 6:507-524.
    • (2001) Eur J Med Res , vol.6 , pp. 507-524
    • Karpov, A.V.1
  • 45
    • 11844289006 scopus 로고    scopus 로고
    • Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C)
    • Schaefer TM, Fahey JV, Wright JA, Wira CR: Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C). J Immunol 2005; 174:992-1002.
    • (2005) J Immunol , vol.174 , pp. 992-1002
    • Schaefer, T.M.1    Fahey, J.V.2    Wright, J.A.3    Wira, C.R.4
  • 46
    • 65749114134 scopus 로고    scopus 로고
    • Polyanionic microbicides modify Toll-like receptor-mediated cervicovaginal immune responses
    • Trifonova RT, Doncel GF, Fichorova RN: Polyanionic microbicides modify Toll-like receptor-mediated cervicovaginal immune responses. Antimicrob Agents Chemother 2009; 53:1490-1500.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1490-1500
    • Trifonova, R.T.1    Doncel, G.F.2    Fichorova, R.N.3
  • 47
    • 77957112425 scopus 로고    scopus 로고
    • Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands
    • Ochiel DO, Ghosh M, Fahey JV, Guyre PM, Wira CR: Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands. J Leukoc Biol 2010; 88:435-444.
    • (2010) J Leukoc Biol , vol.88 , pp. 435-444
    • Ochiel, D.O.1    Ghosh, M.2    Fahey, J.V.3    Guyre, P.M.4    Wira, C.R.5
  • 48
    • 0026586282 scopus 로고
    • Mechanism of HIV spread from lymphocytes to epithelia
    • Philips DM, Bourinbaiar AS: Mechanism of HIV spread from lymphocytes to epithelia. Virology 1992; 186:261-273.
    • (1992) Virology , vol.186 , pp. 261-273
    • Philips, D.M.1    Bourinbaiar, A.S.2
  • 49
    • 0035871775 scopus 로고    scopus 로고
    • Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1
    • Dezzutti CS, Guenthner PC, Cummins JE Jr, Cabrera T, Marshall JH, Dillberger A, Lal RB: Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1. J Infect Dis 2001; 183:1204-1213.
    • (2001) J Infect Dis , vol.183 , pp. 1204-1213
    • Dezzutti, C.S.1    Guenthner, P.C.2    Cummins Jr, J.E.3    Cabrera, T.4    Marshall, J.H.5    Dillberger, A.6    Lal, R.B.7
  • 50
    • 0346243730 scopus 로고    scopus 로고
    • Human genital epithelial cells capture cell-free human immunodeficiency virus type 1 and transmit the virus to CD4+ Cells: implications for mechanisms of sexual transmission
    • Wu Z, Chen Z, Phillips DM: Human genital epithelial cells capture cell-free human immunodeficiency virus type 1 and transmit the virus to CD4+ Cells: implications for mechanisms of sexual transmission. J Infect Dis 2003; 188:1473-1482.
    • (2003) J Infect Dis , vol.188 , pp. 1473-1482
    • Wu, Z.1    Chen, Z.2    Phillips, D.M.3
  • 51
    • 33845992460 scopus 로고    scopus 로고
    • R5- and X4-HIV-1 use differentially the endometrial epithelial cells HEC-1A to ensure their own spread: implication for mechanisms of sexual transmission
    • Saidi H, Magri G, Nasreddine N, Requena M, Belec L: R5- and X4-HIV-1 use differentially the endometrial epithelial cells HEC-1A to ensure their own spread: implication for mechanisms of sexual transmission. Virology 2007; 358:55-68.
    • (2007) Virology , vol.358 , pp. 55-68
    • Saidi, H.1    Magri, G.2    Nasreddine, N.3    Requena, M.4    Belec, L.5
  • 52
    • 0030896192 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 infection of cells and tissues from the upper and lower human female reproductive tract
    • Howell AL, Edkins RD, Rier SE, Yeaman GR, Stern JE, Fanger MW, Wira CR: Human immunodeficiency virus type 1 infection of cells and tissues from the upper and lower human female reproductive tract. J Virol 1997; 71:3498-3506.
    • (1997) J Virol , vol.71 , pp. 3498-3506
    • Howell, A.L.1    Edkins, R.D.2    Rier, S.E.3    Yeaman, G.R.4    Stern, J.E.5    Fanger, M.W.6    Wira, C.R.7
  • 54
    • 0038630425 scopus 로고    scopus 로고
    • Human immunodeficiency virus receptor and coreceptor expression on human uterine epithelial cells: regulation of expression during the menstrual cycle and implications for human immunodeficiency virus infection
    • Yeaman GR, Howell AL, Weldon S, Demian DJ, Collins JE, O'Connell DM, Asin SN, Wira CR, Fanger MW: Human immunodeficiency virus receptor and coreceptor expression on human uterine epithelial cells: regulation of expression during the menstrual cycle and implications for human immunodeficiency virus infection. Immunology 2003; 109:137-146.
    • (2003) Immunology , vol.109 , pp. 137-146
    • Yeaman, G.R.1    Howell, A.L.2    Weldon, S.3    Demian, D.J.4    Collins, J.E.5    O'Connell, D.M.6    Asin, S.N.7    Wira, C.R.8    Fanger, M.W.9
  • 55
    • 0037396322 scopus 로고    scopus 로고
    • Hormonal and embryonic regulation of chemokine receptors CXCR1, CXCR4, CCR5 and CCR2B in the human endometrium and the human blastocyst
    • Dominguez F, Galan A, Martin JJ, Remohi J, Pellicer A, Simon C: Hormonal and embryonic regulation of chemokine receptors CXCR1, CXCR4, CCR5 and CCR2B in the human endometrium and the human blastocyst. Mol Hum Reprod 2003; 9:189-198.
    • (2003) Mol Hum Reprod , vol.9 , pp. 189-198
    • Dominguez, F.1    Galan, A.2    Martin, J.J.3    Remohi, J.4    Pellicer, A.5    Simon, C.6
  • 56
    • 38449113053 scopus 로고    scopus 로고
    • gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission
    • Stoddard E, Cannon G, Ni H, Kariko K, Capodici J, Malamud D, Weissman D: gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission. J Immunol 2007; 179:3126-3132.
    • (2007) J Immunol , vol.179 , pp. 3126-3132
    • Stoddard, E.1    Cannon, G.2    Ni, H.3    Kariko, K.4    Capodici, J.5    Malamud, D.6    Weissman, D.7
  • 61
    • 23844556804 scopus 로고    scopus 로고
    • HIV binding, penetration, and primary infection in human cervicovaginal tissue
    • Maher D, Wu X, Schacker T, Horbul J, Southern P: HIV binding, penetration, and primary infection in human cervicovaginal tissue. Proc Natl Acad Sci USA 2005; 102:11504-11509.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11504-11509
    • Maher, D.1    Wu, X.2    Schacker, T.3    Horbul, J.4    Southern, P.5
  • 62
    • 0031023496 scopus 로고    scopus 로고
    • Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier
    • Bomsel M: Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier. Nat Med 1997; 3:42-47.
    • (1997) Nat Med , vol.3 , pp. 42-47
    • Bomsel, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.