-
1
-
-
84878864199
-
The hallmarks of aging
-
López-Otín, C.; Blasco, M.A.; Partridge, L.; Serrano, M.; Kroemer, G. The hallmarks of aging. Cell 2013, 153, 1194-1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
2
-
-
84903304059
-
Oxidative stress and mitochondrial dysfunction in Alzheimer’s disease
-
Wang, X.; Wang, W.; Li, L.; Perry, G.; Lee, H.-G.; Zhu, X. Oxidative stress and mitochondrial dysfunction in Alzheimer’s disease. Biochim. Biophys. Acta 2014, 1842, 1240-1247.
-
(2014)
Biochim. Biophys. Acta
, vol.1842
, pp. 1240-1247
-
-
Wang, X.1
Wang, W.2
Li, L.3
Perry, G.4
Lee, H.-G.5
Zhu, X.6
-
3
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto, R.I. Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev. 2008, 22, 1427-1438.
-
(2008)
Genes Dev
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
4
-
-
0033972037
-
Possible involvement of proteasome inhibition in aging: Implications for oxidative stress
-
Keller, J.N.; Hanni, K.B.; Markesbery, W.R. Possible involvement of proteasome inhibition in aging: Implications for oxidative stress. Mech. Ageing Dev. 2000, 113, 61-70.
-
(2000)
Mech. Ageing Dev
, vol.113
, pp. 61-70
-
-
Keller, J.N.1
Hanni, K.B.2
Markesbery, W.R.3
-
5
-
-
84901243996
-
Mitochondrial dysfunctions in Parkinson’s disease
-
Gautier, C.A.; Corti, O.; Brice, A. Mitochondrial dysfunctions in Parkinson’s disease. Rev. Neurol.2014, 170, 339-343
-
(2014)
Rev. Neurol
, vol.170
, pp. 339-343
-
-
Gautier, C.A.1
Corti, O.2
Brice, A.3
-
6
-
-
67649756320
-
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson’s disease
-
Büeler, H. Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson’s disease. Exp. Neurol. 2009, 218, 235-246.
-
(2009)
Exp. Neurol
, vol.218
, pp. 235-246
-
-
Büeler, H.1
-
7
-
-
67649425771
-
The proteasomal system
-
Jung, T.; Catalgol, B.; Grune, T. The proteasomal system. Mol. Asp. Med. 2009, 30, 191-296.
-
(2009)
Mol. Asp. Med
, vol.30
, pp. 191-296
-
-
Jung, T.1
Catalgol, B.2
Grune, T.3
-
9
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman, M.H.; Ciechanover, A. The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction. Physiol. Rev. 2002, 82, 373-428.
-
(2002)
Physiol. Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
10
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
Hochstrasser, M. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 1996, 30, 405-439.
-
(1996)
Annu. Rev. Genet
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
11
-
-
84923133994
-
A panoramic overview of mitochondria and mitochondrial redox biology
-
Kim, A. A panoramic overview of mitochondria and mitochondrial redox biology. Toxicol. Res. 2014, 30, 221-234.
-
(2014)
Toxicol. Res
, vol.30
, pp. 221-234
-
-
Kim, A.1
-
12
-
-
84910141948
-
Mitochondrial dynamics and inheritance during cell division, development and disease
-
Mishra, P.; Chan, D.C. Mitochondrial dynamics and inheritance during cell division, development and disease. Nat. Rev. Mol. Cell Biol. 2014, 15, 634-646.
-
(2014)
Nat. Rev. Mol. Cell Biol
, vol.15
, pp. 634-646
-
-
Mishra, P.1
Chan, D.C.2
-
13
-
-
84907212907
-
Cell biology. Metabolic control of cell death
-
Green, D.R.; Galluzzi, L.; Kroemer, G. Cell biology. Metabolic control of cell death. Science 2014, 345, 1250256.
-
(2014)
Science
, vol.345
-
-
Green, D.R.1
Galluzzi, L.2
Kroemer, G.3
-
14
-
-
77049229661
-
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue
-
De Duve, C.; Pressman, B.C.; Gianetto, R.; Wattiaux, R.; Appelmans, F. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem. J. 1955, 60, 604-617.
-
(1955)
Biochem. J
, vol.60
, pp. 604-617
-
-
De Duve, C.1
Pressman, B.C.2
Gianetto, R.3
Wattiaux, R.4
Appelmans, F.5
-
15
-
-
84862737923
-
Changes of the proteasomal system during the aging process
-
Baraibar, M.A.; Friguet, B. Changes of the proteasomal system during the aging process. Prog. Mol. Biol. Transl. Sci. 2012, 109, 249-275.
-
(2012)
Prog. Mol. Biol. Transl. Sci
, vol.109
, pp. 249-275
-
-
Baraibar, M.A.1
Friguet, B.2
-
16
-
-
84864318195
-
Chaperone-mediated autophagy: A unique way to enter the lysosome world
-
Kaushik, S.; Cuervo, A.M. Chaperone-mediated autophagy: A unique way to enter the lysosome world. Trends Cell Biol. 2012, 22, 407-417.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 407-417
-
-
Kaushik, S.1
Cuervo, A.M.2
-
17
-
-
36249025723
-
Autophagy: Process and function
-
Mizushima, N. Autophagy: Process and function. Genes Dev. 2007, 21, 2861-2873.
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
18
-
-
11244309014
-
Proteolysis: From the lysosome to ubiquitin and the proteasome
-
Ciechanover, A. Proteolysis: From the lysosome to ubiquitin and the proteasome. Nat. Rev. Mol. Cell Biol. 2005, 6, 79-87.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 79-87
-
-
Ciechanover, A.1
-
19
-
-
9744227183
-
Ubiquitin: Structures, functions, mechanisms
-
Pickart, C.M.; Eddins, M.J. Ubiquitin: Structures, functions, mechanisms. Biochim. Biophys. Acta 2004, 1695, 55-72.
-
(2004)
Biochim. Biophys. Acta
, vol.1695
, pp. 55-72
-
-
Pickart, C.M.1
Eddins, M.J.2
-
21
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley, D. Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 2009, 78, 477-513.
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
22
-
-
34548188010
-
UBE1L2, a novel E1 enzyme specific for ubiquitin
-
Pelzer, C.; Kassner, I.; Matentzoglu, K.; Singh, R.K.; Wollscheid, H.P.; Scheffner, M.; Schmidtke, G.; Groettrup, M. UBE1L2, a novel E1 enzyme specific for ubiquitin. J. Biol. Chem. 2007, 282, 23010-23014.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 23010-23014
-
-
Pelzer, C.1
Kassner, I.2
Matentzoglu, K.3
Singh, R.K.4
Wollscheid, H.P.5
Scheffner, M.6
Schmidtke, G.7
Groettrup, M.8
-
23
-
-
84858142724
-
HECT and RING finger families of E3 ubiquitin ligases at a glance
-
Metzger, M.B.; Hristova, V.A.; Weissman, A.M. HECT and RING finger families of E3 ubiquitin ligases at a glance. J. Cell Sci. 2012, 125, 531-537.
-
(2012)
J. Cell Sci
, vol.125
, pp. 531-537
-
-
Metzger, M.B.1
Hristova, V.A.2
Weissman, A.M.3
-
24
-
-
9644268864
-
Mechanism and function of deubiquitinating enzymes
-
Amerik, A.Y.; Hochstrasser, M. Mechanism and function of deubiquitinating enzymes. Biochim. Biophys. Acta 2004, 1695, 189-207.
-
(2004)
Biochim. Biophys. Acta
, vol.1695
, pp. 189-207
-
-
Amerik, A.Y.1
Hochstrasser, M.2
-
25
-
-
67650620318
-
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
-
Reyes-Turcu, F.E.; Ventii, K.H.; Wilkinson, K.D. Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu. Rev. Biochem. 2009, 78, 363-397.
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
27
-
-
84856976866
-
Complete subunit architecture of the proteasome regulatory particle
-
Lander, G.C.; Estrin, E.; Matyskiela, M.E.; Bashore, C.; Nogales, E.; Martin, A. Complete subunit architecture of the proteasome regulatory particle. Nature 2012, 482, 186-191.
-
(2012)
Nature
, vol.482
, pp. 186-191
-
-
Lander, G.C.1
Estrin, E.2
Matyskiela, M.E.3
Bashore, C.4
Nogales, E.5
Martin, A.6
-
28
-
-
0029806477
-
The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover
-
Van Nocker, S.; Sadis, S.; Rubin, D.M.; Glickman, M.; Fu, H.; Coux, O.; Wefes, I.; Finley, D.; Vierstra, R.D. The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover. Mol. Cell. Biol. 1996, 16, 6020-6028.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 6020-6028
-
-
Van Nocker, S.1
Sadis, S.2
Rubin, D.M.3
Glickman, M.4
Fu, H.5
Coux, O.6
Wefes, I.7
Finley, D.8
Vierstra, R.D.9
-
29
-
-
0028235965
-
A 26 S protease subunit that binds ubiquitin conjugates
-
Deveraux, Q.; Ustrell, V.; Pickart, C.; Rechsteiner, M. A 26 S protease subunit that binds ubiquitin conjugates. J. Biol. Chem. 1994, 269, 7059-7061.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 7059-7061
-
-
Deveraux, Q.1
Ustrell, V.2
Pickart, C.3
Rechsteiner, M.4
-
30
-
-
44349116590
-
Proteasome subunit Rpn13 is a novel ubiquitin receptor
-
Husnjak, K.; Elsasser, S.; Zhang, N.; Chen, X.; Randles, L.; Shi, Y.; Hofmann, K.; Walters, K.J.; Finley, D.; Dikic, I. Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 2008, 453, 481-488.
-
(2008)
Nature
, vol.453
, pp. 481-488
-
-
Husnjak, K.1
Elsasser, S.2
Zhang, N.3
Chen, X.4
Randles, L.5
Shi, Y.6
Hofmann, K.7
Walters, K.J.8
Finley, D.9
Dikic, I.10
-
31
-
-
0033176770
-
The base of the proteasome regulatory particle exhibits chaperone-like activity
-
Braun, B.C.; Glickman, M.; Kraft, R.; Dahlmann, B.; Kloetzel, P.M.; Finley, D.; Schmidt, M. The base of the proteasome regulatory particle exhibits chaperone-like activity. Nat. Cell Biol. 1999, 1, 221-226.
-
(1999)
Nat. Cell Biol
, vol.1
, pp. 221-226
-
-
Braun, B.C.1
Glickman, M.2
Kraft, R.3
Dahlmann, B.4
Kloetzel, P.M.5
Finley, D.6
Schmidt, M.7
-
32
-
-
33749069075
-
ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome
-
Liu, C.W.; Li, X.; Thompson, D.; Wooding, K.; Chang, T.; Tang, Z.; Yu, H.; Thomas, P.J.; DeMartino, G.N. ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Mol. Cell 2006, 24, 39-50.
-
(2006)
Mol. Cell
, vol.24
, pp. 39-50
-
-
Liu, C.W.1
Li, X.2
Thompson, D.3
Wooding, K.4
Chang, T.5
Tang, Z.6
Yu, H.7
Thomas, P.J.8
Demartino, G.N.9
-
33
-
-
0037131243
-
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome
-
Verma, R.; Aravind, L.; Oania, R.; McDonald, W.H.; Yates, J.R.; Koonin, E.V.; Deshaies, R.J. Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science 2002, 298, 611-615.
-
(2002)
Science
, vol.298
, pp. 611-615
-
-
Verma, R.1
Aravind, L.2
Oania, R.3
McDonald, W.H.4
Yates, J.R.5
Koonin, E.V.6
Deshaies, R.J.7
-
34
-
-
84862556334
-
Biochemistry and evolution of anaerobic energy metabolism in eukaryotes
-
Müller, M.; Mentel, M.; van Hellemond, J.J.; Henze, K.; Woehle, C.; Gould, S.B.; Yu, R.Y.; van der Giezen, M.; Tielens, A.G.; Martin, W.F. Biochemistry and evolution of anaerobic energy metabolism in eukaryotes. Microbiol. Mol. Biol. Rev. 2012, 76, 444-495.
-
(2012)
Microbiol. Mol. Biol. Rev
, vol.76
, pp. 444-495
-
-
Müller, M.1
Mentel, M.2
Van Hellemond, J.J.3
Henze, K.4
Woehle, C.5
Gould, S.B.6
Yu, R.Y.7
Van Der Giezen, M.8
Tielens, A.G.9
Martin, W.F.10
-
35
-
-
84879471478
-
Mitochondrial network morphology: Buildingan integrative, geometrical view
-
Rafelski, S.M. Mitochondrial network morphology: Building an integrative, geometrical view. BMC Biol. 2013, doi:10.1186/1741-7007-11-71.
-
(2013)
BMC Biol
-
-
Rafelski, S.M.1
-
36
-
-
84897877057
-
Regulation of mitochondrial dynamics and cell fate
-
Dhingra, R.; Kirshenbaum, L.A. Regulation of mitochondrial dynamics and cell fate. Circ. J. 2014, 78, 803-810.
-
(2014)
Circ. J
, vol.78
, pp. 803-810
-
-
Dhingra, R.1
Kirshenbaum, L.A.2
-
38
-
-
68949163004
-
The cell-type specificity of mitochondrial dynamics
-
Kuznetsov, A.V.; Hermann, M.; Saks, V.; Hengster, P.; Margreiter, R. The cell-type specificity of mitochondrial dynamics. Int. J. Biochem. Cell Biol. 2009, 41, 1928-1939.
-
(2009)
Int. J. Biochem. Cell Biol
, vol.41
, pp. 1928-1939
-
-
Kuznetsov, A.V.1
Hermann, M.2
Saks, V.3
Hengster, P.4
Margreiter, R.5
-
39
-
-
67149094710
-
Heterogeneity of mitochondria and mitochondrial function within cells as another level of mitochondrial complexity
-
Kuznetsov, A.V.; Margreiter, R. Heterogeneity of mitochondria and mitochondrial function within cells as another level of mitochondrial complexity. Int. J. Mol. Sci. 2009, 10, 1911-1929.
-
(2009)
Int. J. Mol. Sci
, vol.10
, pp. 1911-1929
-
-
Kuznetsov, A.V.1
Margreiter, R.2
-
40
-
-
46349103594
-
A mitochondrial protein compendium elucidates complex I disease biology
-
Pagliarini, D.J.; Calvo, S.E.; Chang, B.; Sheth, S.A.; Vafai, S.B.; Ong, S.E.; Walford, G.A.; Sugiana, C.; Boneh, A.; Chen, W.K. A mitochondrial protein compendium elucidates complex I disease biology. Cell 2008, 134, 112-123.
-
(2008)
Cell
, vol.134
, pp. 112-123
-
-
Pagliarini, D.J.1
Calvo, S.E.2
Chang, B.3
Sheth, S.A.4
Vafai, S.B.5
Ong, S.E.6
Walford, G.A.7
Sugiana, C.8
Boneh, A.9
Chen, W.K.10
-
41
-
-
68749112707
-
Importing mitochondrial proteins: Machineries and mechanisms
-
Chacinska, A.; Koehler, C.M.; Milenkovic, D.; Lithgow, T.; Pfanner, N. Importing mitochondrial proteins: Machineries and mechanisms. Cell 2009, 138, 628-644.
-
(2009)
Cell
, vol.138
, pp. 628-644
-
-
Chacinska, A.1
Koehler, C.M.2
Milenkovic, D.3
Lithgow, T.4
Pfanner, N.5
-
42
-
-
34848823742
-
Mitochondrial protein-import machinery: Correlating structure with function
-
Baker, M.J.; Frazier, A.E.; Gulbis, J.M.; Ryan, M.T. Mitochondrial protein-import machinery: Correlating structure with function. Trends Cell Biol. 2007, 17, 456-464.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 456-464
-
-
Baker, M.J.1
Frazier, A.E.2
Gulbis, J.M.3
Ryan, M.T.4
-
43
-
-
84897390686
-
Mitochondrial protein quality control in health and disease
-
Baker, M.J.; Palmer, C.S.; Stojanovski, D. Mitochondrial protein quality control in health and disease. Br. J. Pharmacol. 2014, 171, 1870-1889.
-
(2014)
Br. J. Pharmacol
, vol.171
, pp. 1870-1889
-
-
Baker, M.J.1
Palmer, C.S.2
Stojanovski, D.3
-
45
-
-
84897472990
-
The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control
-
Voos, W.; Ward, L.A.; Truscott, K.N. The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control. Subcell Biochem. 2013, 66, 223-263.
-
(2013)
Subcell Biochem
, vol.66
, pp. 223-263
-
-
Voos, W.1
Ward, L.A.2
Truscott, K.N.3
-
46
-
-
80053352130
-
Mitochondrial quality control by the ubiquitin-proteasome system
-
Taylor, E.B.; Rutter, J. Mitochondrial quality control by the ubiquitin-proteasome system. Biochem. Soc. Trans. 2011, 39, 1509-1513.
-
(2011)
Biochem. Soc. Trans
, vol.39
, pp. 1509-1513
-
-
Taylor, E.B.1
Rutter, J.2
-
47
-
-
0038037754
-
Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast
-
Fritz, S.; Weinbach, N.; Westermann, B. Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast. Mol. Biol. Cell 2003, 14, 2303-2313.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 2303-2313
-
-
Fritz, S.1
Weinbach, N.2
Westermann, B.3
-
48
-
-
0345687191
-
The proteome of Saccharomyces cerevisiae mitochondria
-
Sickmann, A.; Reinders, J.; Wagner, Y.; Joppich, C.; Zahedi, R.; Meyer, H.E.; Schönfisch, B.; Perschil, I.; Chacinska, A.; Guiard, B. The proteome of Saccharomyces cerevisiae mitochondria. Proc. Natl. Acad. Sci. USA 2003, 100, 13207-13212.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13207-13212
-
-
Sickmann, A.1
Reinders, J.2
Wagner, Y.3
Joppich, C.4
Zahedi, R.5
Meyer, H.E.6
Schönfisch, B.7
Perschil, I.8
Chacinska, A.9
Guiard, B.10
-
49
-
-
34247528121
-
A proteomics approach to identify the ubiquitinated proteins in mouse heart
-
Jeon, H.B.; Choi, E.S.; Yoon, J.H.; Hwang, J.H.; Chang, J.W.; Lee, E.K.; Choi, H.W.; Park, Z.Y.; Yoo, Y.J. A proteomics approach to identify the ubiquitinated proteins in mouse heart. Biochem. Biophys. Res. Commun. 2007, 357, 731-736.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.357
, pp. 731-736
-
-
Jeon, H.B.1
Choi, E.S.2
Yoon, J.H.3
Hwang, J.H.4
Chang, J.W.5
Lee, E.K.6
Choi, H.W.7
Park, Z.Y.8
Yoo, Y.J.9
-
50
-
-
0034643336
-
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
-
Schubert, U.; Antón, L.C.; Gibbs, J.; Norbury, C.C.; Yewdell, J.W.; Bennink, J.R. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 2000, 404, 770-774.
-
(2000)
Nature
, vol.404
, pp. 770-774
-
-
Schubert, U.1
Antón, L.C.2
Gibbs, J.3
Norbury, C.C.4
Yewdell, J.W.5
Bennink, J.R.6
-
51
-
-
78649527772
-
Stressed-out mitochondria get MAD
-
Chatenay-Lapointe, M.; Shadel, G.S. Stressed-out mitochondria get MAD. Cell Metab. 2010, 12, 559-560.
-
(2010)
Cell Metab
, vol.12
, pp. 559-560
-
-
Chatenay-Lapointe, M.1
Shadel, G.S.2
-
52
-
-
78149429951
-
A stress-responsive system for mitochondrial protein degradation
-
Heo, J.-M.; Livnat-Levanon, N.; Taylor, E.B.; Jones, K.T.; Dephoure, N.; Ring, J.; Xie, J.; Brodsky, J.L.; Madeo, F.; Gygi, S.P. A stress-responsive system for mitochondrial protein degradation. Mol. Cell 2010, 40, 465-480.
-
(2010)
Mol. Cell
, vol.40
, pp. 465-480
-
-
Heo, J.-M.1
Livnat-Levanon, N.2
Taylor, E.B.3
Jones, K.T.4
Dephoure, N.5
Ring, J.6
Xie, J.7
Brodsky, J.L.8
Madeo, F.9
Gygi, S.P.10
-
53
-
-
38449107710
-
Outer mitochondrial membrane protein degradation by the proteasome
-
Neutzner, A.; Youle, R.J.; Karbowski, M. Outer mitochondrial membrane protein degradation by the proteasome. Novartis Found. Symp. 2007, 287, 4-14.
-
(2007)
Novartis Found. Symp
, vol.287
, pp. 4-14
-
-
Neutzner, A.1
Youle, R.J.2
Karbowski, M.3
-
54
-
-
42449147510
-
Hsp90 inhibition decreases mitochondrial protein turnover
-
Margineantu, D.H.; Emerson, C.B.; Diaz, D.; Hockenbery, D.M. Hsp90 inhibition decreases mitochondrial protein turnover. PLoS ONE 2007, 2, e1066.
-
(2007)
Plos ONE
, vol.2
-
-
Margineantu, D.H.1
Emerson, C.B.2
Diaz, D.3
Hockenbery, D.M.4
-
55
-
-
76649093912
-
Degradation of an intramitochondrial protein by the cytosolic proteasome
-
Azzu, V.; Brand, M.D. Degradation of an intramitochondrial protein by the cytosolic proteasome. J. Cell Sci. 2010, 123, 578-585.
-
(2010)
J. Cell Sci
, vol.123
, pp. 578-585
-
-
Azzu, V.1
Brand, M.D.2
-
56
-
-
84864703396
-
A role for ubiquitinylation and the cytosolic proteasome in turnover of mitochondrial uncoupling protein 1 (UCP1)
-
Clarke, K.J.; Adams, A.E.; Manzke, L.H.; Pearson, T.W.; Borchers, C.H.; Porter, R.K. A role for ubiquitinylation and the cytosolic proteasome in turnover of mitochondrial uncoupling protein 1 (UCP1). Biochim. Biophys. Acta 2012, 1817, 1759-1767.
-
(2012)
Biochim. Biophys. Acta
, vol.1817
, pp. 1759-1767
-
-
Clarke, K.J.1
Adams, A.E.2
Manzke, L.H.3
Pearson, T.W.4
Borchers, C.H.5
Porter, R.K.6
-
57
-
-
45149128904
-
Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi
-
Radke, S.; Chander, H.; Schäfer, P.; Meiss, G.; Krüger, R.; Schulz, J.B.; Germain, D. Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi. J. Biol. Chem. 2008, 283, 12681-12685.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 12681-12685
-
-
Radke, S.1
Chander, H.2
Schäfer, P.3
Meiss, G.4
Krüger, R.5
Schulz, J.B.6
Germain, D.7
-
58
-
-
79551663809
-
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
-
Xu, S.; Peng, G.; Wang, Y.; Fang, S.; Karbowski, M. The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover. Mol. Biol. Cell. 2011, 22, 291-300.
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 291-300
-
-
Xu, S.1
Peng, G.2
Wang, Y.3
Fang, S.4
Karbowski, M.5
-
59
-
-
84924589411
-
Accumulation of basic amino acids at mitochondria dictates the cytotoxicity of aberrant ubiquitin
-
Braun, R.J.; Sommer, C.; Leibiger, C.; Gentier, R.J.G.; Dumit, V.I.; Paduch, K.; Eisenberg, T.; Habernig, L.; Trausinger, G.; Magnes, C. Accumulation of basic amino acids at mitochondria dictates the cytotoxicity of aberrant ubiquitin. Cell Rep. 2015, doi:10.1016/j.celrep.2015.02.009.
-
(2015)
Cell Rep
-
-
Braun, R.J.1
Sommer, C.2
Leibiger, C.3
Gentier, R.4
Dumit, V.I.5
Paduch, K.6
Eisenberg, T.7
Habernig, L.8
Trausinger, G.9
Magnes, C.10
-
60
-
-
84876079328
-
Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels
-
Bartolome, F.; Wu, H.C.; Burchell, V.S.; Preza, E.; Wray, S.; Mahoney, C.J; Fox, N.C.; Calvo, A.; Canosa, A.; Moglia, C.; et al.Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels. Neuron 2013, 78, 57-64.
-
(2013)
Neuron
, vol.78
, pp. 57-64
-
-
Bartolome, F.1
Wu, H.C.2
Burchell, V.S.3
Preza, E.4
Wray, S.5
Mahoney, C.J.6
Fox, N.C.7
Calvo, A.8
Canosa, A.9
Moglia, C.10
-
61
-
-
33748743100
-
Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast
-
Braun, R.J.; Zischka, H.; Madeo, F.; Eisenberg, T.; Wissing, S.; Büttner, S.; Engelhardt, S.M.; Büringer, D.; Ueffing, M. Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast. J. Biol. Chem. 2006, 281, 25757-25767.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 25757-25767
-
-
Braun, R.J.1
Zischka, H.2
Madeo, F.3
Eisenberg, T.4
Wissing, S.5
Büttner, S.6
Engelhardt, S.M.7
Büringer, D.8
Ueffing, M.9
-
62
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T.; Asakawa, S.; Hattori, N.; Matsumine, H.; Yamamura, Y.; Minoshima, S.; Yokochi, M.; Mizuno, Y.; Shimizu, N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392, 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
63
-
-
84940723006
-
Molecular mechanisms underlying PINK1 and Parkin catalyzed ubiquitylation of substrates on damaged mitochondria
-
Koyano, F.; Matsuda, N. Molecular mechanisms underlying PINK1 and Parkin catalyzed ubiquitylation of substrates on damaged mitochondria. Biochim. Biophys. Acta 2015, doi:10.1016/j.bbamcr.2015.02.009.
-
(2015)
Biochim. Biophys. Acta
-
-
Koyano, F.1
Matsuda, N.2
-
64
-
-
79957949190
-
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
-
Wenzel, D.M.; Lissounov, A.; Brzovic, P.S.; Klevit, R.E. UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature 2011, 474, 105-108.
-
(2011)
Nature
, vol.474
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
65
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda, N.; Sato, S.; Shiba, K.; Okatsu, K.; Saisho, K.; Gautier, C.A.; Sou, Y.S.; Saiki, S.; Kawajiri, S.; Sato, F.; Kimura, M.; et al.PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol. 2010, 189, 211-221.
-
(2010)
J. Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
Sou, Y.S.7
Saiki, S.8
Kawajiri, S.9
Sato, F.10
Kimura, M.11
-
66
-
-
84899539731
-
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
-
Kane, L.A.; Lazarou, M.; Fogel, A.I.; Li, Y.; Yamano, K.; Sarraf, S.A.; Banerjee, S.; Youle, R.J. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J. Cell Biol. 2014, 205, 143-153.
-
(2014)
J. Cell Biol
, vol.205
, pp. 143-153
-
-
Kane, L.A.1
Lazarou, M.2
Fogel, A.I.3
Li, Y.4
Yamano, K.5
Sarraf, S.A.6
Banerjee, S.7
Youle, R.J.8
-
67
-
-
84901751574
-
Ubiquitin is phosphorylated by PINK1 to activate parkin
-
Koyano, F.; Okatsu, K.; Kosako, H.; Tamura, Y.; Go, E.; Kimura, M.; Kimura, Y.; Tsuchiya, H.; Yoshihara, H.; Hirokawa, T.; et al.Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 2014, 510, 162-166.
-
(2014)
Nature
, vol.510
, pp. 162-166
-
-
Koyano, F.1
Okatsu, K.2
Kosako, H.3
Tamura, Y.4
Go, E.5
Kimura, M.6
Kimura, Y.7
Tsuchiya, H.8
Yoshihara, H.9
Hirokawa, T.10
-
68
-
-
84899421556
-
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
-
Kazlauskaite, A.; Kondapalli, C.; Gourlay, R.; Campbell, D.G.; Ritorto, M.S.; Hofmann, K.; Alessi, D.R.; Knebel, A.; Trost, M.; Muqit, M.M.K. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65. Biochem. J. 2014, 460, 127-139.
-
(2014)
Biochem. J
, vol.460
, pp. 127-139
-
-
Kazlauskaite, A.1
Kondapalli, C.2
Gourlay, R.3
Campbell, D.G.4
Ritorto, M.S.5
Hofmann, K.6
Alessi, D.R.7
Knebel, A.8
Trost, M.9
Muqit, M.10
-
69
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler, S.; Holmström, K.M.; Skujat, D.; Fiesel, F.C.; Rothfuss, O.C.; Kahle, P.J.; Springer, W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol.2010, 12, 119-131.
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
70
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser, L.; Sonnay, S.; Stafa, K.; Moore, D.J. Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J. Neurochem.2011, 118, 636-645.
-
(2011)
J. Neurochem
, vol.118
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
Stafa, K.3
Moore, D.J.4
-
71
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra, D.; Tanaka, A.; Suen, D.-F.; Youle, R.J. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 2008, 183, 795-803.
-
(2008)
J. Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.-F.3
Youle, R.J.4
-
72
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
Sarraf, S.A.; Raman, M.; Guarani-Pereira, V.; Sowa, M.E.; Huttlin, E.L.; Gygi, S.P.; Harper, J.W. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 2013, 496, 372-376.
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
Harper, J.W.7
-
73
-
-
84878118233
-
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
-
Rana, A.; Rera, M.; Walker, D.W. Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan. Proc. Natl. Acad. Sci. USA 2013, 110, 8638-8643.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 8638-8643
-
-
Rana, A.1
Rera, M.2
Walker, D.W.3
-
74
-
-
33747591029
-
Parkinson’s disease: A rethink of rodent models
-
Melrose, H.L.; Lincoln, S.J.; Tyndall, G.M.; Farrer, M.J. Parkinson’s disease: A rethink of rodent models. Exp. Brain Res. 2006, 173, 196-204.
-
(2006)
Exp. Brain Res
, vol.173
, pp. 196-204
-
-
Melrose, H.L.1
Lincoln, S.J.2
Tyndall, G.M.3
Farrer, M.J.4
-
75
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky, F.H.; Lee, S.; Wibom, R.; Olson, L.; Larsson, N.G. Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc. Natl. Acad. Sci. USA 2011, 108, 12937-12942.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
76
-
-
84899806692
-
Roles of mitochondrial ubiquitin ligase MITOL/MARCH5 in mitochondrial dynamics and diseases
-
Nagashima, S.; Tokuyama, T.; Yonashiro, R.; Inatome, R.; Yanagi, S. Roles of mitochondrial ubiquitin ligase MITOL/MARCH5 in mitochondrial dynamics and diseases. J. Biochem. 2014, 155, 273-279.
-
(2014)
J. Biochem
, vol.155
, pp. 273-279
-
-
Nagashima, S.1
Tokuyama, T.2
Yonashiro, R.3
Inatome, R.4
Yanagi, S.5
-
77
-
-
34347398050
-
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
-
Karbowski, M.; Neutzner, A.; Youle, R.J. The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J. Cell Biol. 2007, 178, 71-84.
-
(2007)
J. Cell Biol
, vol.178
, pp. 71-84
-
-
Karbowski, M.1
Neutzner, A.2
Youle, R.J.3
-
78
-
-
33747613595
-
A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics
-
Yonashiro, R.; Ishido, S.; Kyo, S.; Fukuda, T.; Goto, E.; Matsuki, Y.; Ohmura-Hoshino, M.; Sada, K.; Hotta, H.; Yamamura, H.; et al.A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics. EMBO J. 2006, 25, 3618-3626.
-
(2006)
EMBO J
, vol.25
, pp. 3618-3626
-
-
Yonashiro, R.1
Ishido, S.2
Kyo, S.3
Fukuda, T.4
Goto, E.5
Matsuki, Y.6
Ohmura-Hoshino, M.7
Sada, K.8
Hotta, H.9
Yamamura, H.10
-
79
-
-
73949112709
-
Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation
-
Yonashiro, R.; Sugiura, A.; Miyachi, M.; Fukuda, T.; Matsushita, N.; Inatome, R.; Ogata, Y.; Suzuki, T.; Dohmae, N.; Yanagi, S. Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation. Mol. Biol. Cell 2009, 20, 4524-4530.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4524-4530
-
-
Yonashiro, R.1
Sugiura, A.2
Miyachi, M.3
Fukuda, T.4
Matsushita, N.5
Inatome, R.6
Ogata, Y.7
Suzuki, T.8
Dohmae, N.9
Yanagi, S.10
-
80
-
-
79955964218
-
The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
-
Durcan, T.M.; Kontogiannea, M.; Thorarinsdottir, T.; Fallon, L.; Williams, A.J.; Djarmati, A.; Fantaneanu, T.; Paulson, H.L.; Fon, E.A. The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Hum. Mol. Genet.2011, 20, 141-154.
-
(2011)
Hum. Mol. Genet
, vol.20
, pp. 141-154
-
-
Durcan, T.M.1
Kontogiannea, M.2
Thorarinsdottir, T.3
Fallon, L.4
Williams, A.J.5
Djarmati, A.6
Fantaneanu, T.7
Paulson, H.L.8
Fon, E.A.9
-
81
-
-
84876903554
-
Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 upon mitochondrial dysfunction in neurons
-
Huang, Q.; Wang, H.; Perry, S.W.; Figueiredo-Pereira, M.E. Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 upon mitochondrial dysfunction in neurons. J. Biol. Chem. 2013, 288, 12161-12174.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 12161-12174
-
-
Huang, Q.1
Wang, H.2
Perry, S.W.3
Figueiredo-Pereira, M.E.4
-
82
-
-
84902330507
-
Reversible 26S proteasome disassembly upon mitochondrial stress
-
Livnat-Levanon, N.; Kevei, É.; Kleifeld, O.; Krutauz, D.; Segref, A.; Rinaldi, T.; Erpapazoglou, Z.; Cohen, M.; Reis, N.; Hoppe, T.; et al.Reversible 26S proteasome disassembly upon mitochondrial stress. Cell Rep. 2014, 7, 1371-1380.
-
(2014)
Cell Rep
, vol.7
, pp. 1371-1380
-
-
Livnat-Levanon, N.1
Kevei, É.2
Kleifeld, O.3
Krutauz, D.4
Segref, A.5
Rinaldi, T.6
Erpapazoglou, Z.7
Cohen, M.8
Reis, N.9
Hoppe, T.10
-
83
-
-
84897528338
-
Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system
-
Segref, A.; Kevei, É.; Pokrzywa, W.; Schmeisser, K.; Mansfeld, J.; Livnat-Levanon, N.; Ensenauer, R.; Glickman, M.H.; Ristow, M.; Hoppe, T.Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system. Cell Metab. 2014, 19, 642-652.
-
(2014)
Cell Metab
, vol.19
, pp. 642-652
-
-
Segref, A.1
Kevei, É.2
Pokrzywa, W.3
Schmeisser, K.4
Mansfeld, J.5
Livnat-Levanon, N.6
Ensenauer, R.7
Glickman, M.H.8
Ristow, M.9
Hoppe, T.10
-
84
-
-
0029984892
-
Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome
-
Grune, T.; Reinheckel, T.; Davies, K.J. Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. J. Biol. Chem. 1996, 271, 15504-15509.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 15504-15509
-
-
Grune, T.1
Reinheckel, T.2
Davies, K.J.3
-
85
-
-
0038239701
-
Selective degradation of oxidatively modified protein substrates by the proteasome
-
Grune, T.; Merker, K.; Sandig, G.; Davies, K.J.A. Selective degradation of oxidatively modified protein substrates by the proteasome. Biochem. Biophys. Res. Commun. 2003, 305, 709-718.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.305
, pp. 709-718
-
-
Grune, T.1
Merker, K.2
Sandig, G.3
Davies, K.4
-
86
-
-
0037414834
-
Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome
-
Shringarpure, R.; Grune, T.; Mehlhase, J.; Davies, K.J.A. Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J. Biol. Chem. 2003, 278, 311-318.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 311-318
-
-
Shringarpure, R.1
Grune, T.2
Mehlhase, J.3
Davies, K.4
-
87
-
-
0021099710
-
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown
-
Hershko, A.; Heller, H.; Elias, S.; Ciechanover, A. Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown. J. Biol. Chem. 1983, 258, 8206-8214.
-
(1983)
J. Biol. Chem
, vol.258
, pp. 8206-8214
-
-
Hershko, A.1
Heller, H.2
Elias, S.3
Ciechanover, A.4
-
88
-
-
0024413057
-
ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin
-
Eytan, E.; Ganoth, D.; Armon, T.; Hershko, A. ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin. Proc. Natl. Acad. Sci. USA 1989, 86, 7751-7755.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7751-7755
-
-
Eytan, E.1
Ganoth, D.2
Armon, T.3
Hershko, A.4
-
89
-
-
0029039632
-
Studies on the activation by ATP of the 26 S proteasome complex from rat skeletal muscle
-
Dahlmann, B.; Kuehn, L.; Reinauer, H. Studies on the activation by ATP of the 26 S proteasome complex from rat skeletal muscle. Biochem. J. 1995, 309, 195-202.
-
(1995)
Biochem. J
, vol.309
, pp. 195-202
-
-
Dahlmann, B.1
Kuehn, L.2
Reinauer, H.3
-
90
-
-
36849059755
-
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites
-
Kleijnen, M.F.; Roelofs, J.; Park, S.; Hathaway, N.A.; Glickman, M.; King, R.W.; Finley, D. Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites. Nat. Struct. Mol. Biol. 2007, 14, 1180-1188.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 1180-1188
-
-
Kleijnen, M.F.1
Roelofs, J.2
Park, S.3
Hathaway, N.A.4
Glickman, M.5
King, R.W.6
Finley, D.7
-
91
-
-
78649894468
-
Physiological levels of ATP negatively regulate proteasome function
-
Huang, H.; Zhang, X.; Li, S.; Liu, N.; Lian, W.; McDowell, E.; Zhou, P.; Zhao, C.; Guo, H.; Zhang, C.; et al. Physiological levels of ATP negatively regulate proteasome function. Cell Res. 2010, 20, 1372-1385.
-
(2010)
Cell Res
, vol.20
, pp. 1372-1385
-
-
Huang, H.1
Zhang, X.2
Li, S.3
Liu, N.4
Lian, W.5
McDowell, E.6
Zhou, P.7
Zhao, C.8
Guo, H.9
Zhang, C.10
-
92
-
-
0041430614
-
Dysfunction of mitochondrial complex I and the proteasome: Interactions between two biochemical deficits in a cellular model of Parkinson’s disease
-
Höglinger, G.U.; Carrard, G.; Michel, P.P.; Medja, F.; Lombès, A.; Ruberg, M.; Friguet, B.; Hirsch, E.C. Dysfunction of mitochondrial complex I and the proteasome: Interactions between two biochemical deficits in a cellular model of Parkinson’s disease. J. Neurochem. 2003, 86, 1297-1307.
-
(2003)
J. Neurochem
, vol.86
, pp. 1297-1307
-
-
Höglinger, G.U.1
Carrard, G.2
Michel, P.P.3
Medja, F.4
Lombès, A.5
Ruberg, M.6
Friguet, B.7
Hirsch, E.C.8
-
93
-
-
4043143475
-
Proteasome synthesis and assembly are required for survival during stationary phase
-
Chen, Q.; Thorpe, J.; Ding, Q.; El-Amouri, I.S.; Keller, J.N. Proteasome synthesis and assembly are required for survival during stationary phase. Free Radic. Biol. Med. 2004, 37, 859-868.
-
(2004)
Free Radic. Biol. Med
, vol.37
, pp. 859-868
-
-
Chen, Q.1
Thorpe, J.2
Ding, Q.3
El-Amouri, I.S.4
Keller, J.N.5
-
94
-
-
34548479261
-
Aging perturbs 26S proteasome assembly in Drosophila melanogaster
-
Vernace, V.A.; Arnaud, L.; Schmidt-Glenewinkel, T.; Figueiredo-Pereira, M.E. Aging perturbs 26S proteasome assembly in Drosophila melanogaster. FASEB J. 2007, 21, 2672-2682.
-
(2007)
FASEB J
, vol.21
, pp. 2672-2682
-
-
Vernace, V.A.1
Arnaud, L.2
Schmidt-Glenewinkel, T.3
Figueiredo-Pereira, M.E.4
-
95
-
-
0034087369
-
Decreased levels of proteasome activity and proteasome expression in aging spinal cord
-
Keller, J.N.; Huang, F.F.; Markesbery, W.R. Decreased levels of proteasome activity and proteasome expression in aging spinal cord. Neuroscience 2000, 98, 149-156.
-
(2000)
Neuroscience
, vol.98
, pp. 149-156
-
-
Keller, J.N.1
Huang, F.F.2
Markesbery, W.R.3
-
96
-
-
71849084532
-
Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver
-
Dasuri, K.; Zhang, L.; Ebenezer, P.; Liu, Y.; Fernandez-Kim, S.O.; Keller, J.N. Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver. Mech. Ageing Dev. 2009, 130, 777-783.
-
(2009)
Mech. Ageing Dev
, vol.130
, pp. 777-783
-
-
Dasuri, K.1
Zhang, L.2
Ebenezer, P.3
Liu, Y.4
Fernandez-Kim, S.O.5
Keller, J.N.6
-
97
-
-
16344363800
-
Altered proteasome structure, function, and oxidation in aged muscle
-
Ferrington, D.A.; Husom, A.D.; Thompson, L.V. Altered proteasome structure, function, and oxidation in aged muscle. FASEB J. 2005, 19, 644-646.
-
(2005)
FASEB J
, vol.19
, pp. 644-646
-
-
Ferrington, D.A.1
Husom, A.D.2
Thompson, L.V.3
-
98
-
-
34447514375
-
Age-associated decrease in proteasome content and activities in human dermal fibroblasts: Restoration of normal level of proteasome subunits reduces aging markers in fibroblasts from elderly persons
-
Hwang, J.S.; Hwang, J.S.; Chang, I.; Kim, S. Age-associated decrease in proteasome content and activities in human dermal fibroblasts: Restoration of normal level of proteasome subunits reduces aging markers in fibroblasts from elderly persons. J. Gerontol. A Biol. Sci. Med. Sci. 2007, 62, 490-499.
-
(2007)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.62
, pp. 490-499
-
-
Hwang, J.S.1
Hwang, J.S.2
Chang, I.3
Kim, S.4
-
99
-
-
84931570247
-
Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases
-
Chondrogianni, N.; Voutetakis, K.; Kapetanou, M.; Delitsikou, V.; Papaevgeniou, N.; Sakellari, M.; Lefaki, M.; Filippopoulou, K.; Gonos, E.S.Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases. Ageing Res. Rev.2015, 23, 37-55.
-
(2015)
Ageing Res. Rev
, vol.23
, pp. 37-55
-
-
Chondrogianni, N.1
Voutetakis, K.2
Kapetanou, M.3
Delitsikou, V.4
Papaevgeniou, N.5
Sakellari, M.6
Lefaki, M.7
Filippopoulou, K.8
Gonos, E.S.9
-
100
-
-
34548624245
-
Aging and regulated protein degradation: Who has the UPPer hand?
-
Vernace, V.A.; Schmidt-Glenewinkel, T.; Figueiredo-Pereira, M.E. Aging and regulated protein degradation: Who has the UPPer hand? Aging Cell. 2007, 6, 599-606.
-
(2007)
Aging Cell
, vol.6
, pp. 599-606
-
-
Vernace, V.A.1
Schmidt-Glenewinkel, T.2
Figueiredo-Pereira, M.E.3
-
101
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman, D. Aging: A theory based on free radical and radiation chemistry. J. Gerontol.1956, 11, 298-300.
-
(1956)
J. Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
102
-
-
0029113657
-
High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys
-
Schwarze, S.R.; Lee, C.M.; Chung, S.S.; Roecker, E.B.; Weindruch, R.; Aiken, J.M. High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys. Mech. Ageing Dev. 1995, 83, 91-101.
-
(1995)
Mech. Ageing Dev
, vol.83
, pp. 91-101
-
-
Schwarze, S.R.1
Lee, C.M.2
Chung, S.S.3
Roecker, E.B.4
Weindruch, R.5
Aiken, J.M.6
-
103
-
-
0037448025
-
Accumulation of point mutations in mitochondrial DNA of aging mice
-
Khaidakov, M.; Heflich, R.H.; Manjanatha, M.G.; Myers, M.B.; Aidoo, A. Accumulation of point mutations in mitochondrial DNA of aging mice. Mutat. Res. 2003, 526, 1-7.
-
(2003)
Mutat. Res
, vol.526
, pp. 1-7
-
-
Khaidakov, M.1
Heflich, R.H.2
Manjanatha, M.G.3
Myers, M.B.4
Aidoo, A.5
-
104
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski, M.; Horton, T.; Lott, M.T.; Shoffner, J.M.; Beal, M.F.; Wallace, D.C. Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age. Nat. Genet. 1992, 2, 324-329.
-
(1992)
Nat. Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
105
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
Soong, N.W.; Hinton, D.R.; Cortopassi, G.; Arnheim, N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nat. Genet. 1992, 2, 318-323.
-
(1992)
Nat. Genet
, vol.2
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
Cortopassi, G.3
Arnheim, N.4
-
106
-
-
84884416043
-
Germline mitochondrial DNA mutations aggravate ageing and can impair brain development
-
Ross, J.M.; Stewart, J.B.; Hagström, E.; Brené, S.; Mourier, A.; Coppotelli, G.; Freyer, C.; Lagouge, M.; Hoffer, B.J.; Olson, L.; et al.Germline mitochondrial DNA mutations aggravate ageing and can impair brain development. Nature 2013, 501, 412-415.
-
(2013)
Nature
, vol.501
, pp. 412-415
-
-
Ross, J.M.1
Stewart, J.B.2
Hagström, E.3
Brené, S.4
Mourier, A.5
Coppotelli, G.6
Freyer, C.7
Lagouge, M.8
Hoffer, B.J.9
Olson, L.10
-
107
-
-
78650533229
-
High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio
-
Ross, J.M.; Öberg, J.; Brené, S.; Coppotelli, G.; Terzioglu, M.; Pernold, K.; Goiny, M.; Sitnikov, R.; Kehr, J.; Trifunovic, A.; et al.High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio. Proc. Natl. Acad. Sci. USA 2010, 107, 20087-20092.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 20087-20092
-
-
Ross, J.M.1
Öberg, J.2
Brené, S.3
Coppotelli, G.4
Terzioglu, M.5
Pernold, K.6
Goiny, M.7
Sitnikov, R.8
Kehr, J.9
Trifunovic, A.10
-
108
-
-
84931346628
-
Maternally transmitted mitochondrial DNA mutations can reduce lifespan
-
Ross, J.M.; Coppotelli, G.; Hoffer, B.J.; Olson, L. Maternally transmitted mitochondrial DNA mutations can reduce lifespan. Sci. Rep. 2014, doi:10.1038/srep06569.
-
(2014)
Sci. Rep
-
-
Ross, J.M.1
Coppotelli, G.2
Hoffer, B.J.3
Olson, L.4
-
109
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic, A.; Wredenberg, A.; Falkenberg, M.; Spelbrink, J.N.; Rovio, A.T.; Bruder, C.E.; Bohlooly, Y.M.; Gidlöf, S.; Oldfors, A.; Wibom, R.; et al.Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 2004, 429, 417-423.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlöf, S.8
Oldfors, A.9
Wibom, R.10
-
110
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth, G.C.; Hiona, A.; Pugh, T.D.; Someya, S.; Panzer, K.; Wohlgemuth, S.E.; Hofer, T.; Seo, A.Y.; Sullivan, R.; Jobling, W.A.; et al.Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 2005, 309, 481-484.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
-
113
-
-
68649118090
-
A critical evaluation of the ubiquitin-proteasome system in Parkinson’s disease
-
Cook, C.; Petrucelli, L. A critical evaluation of the ubiquitin-proteasome system in Parkinson’s disease. Biochim. Biophys. Acta 2009, 1792, 664-675.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 664-675
-
-
Cook, C.1
Petrucelli, L.2
-
114
-
-
33846636481
-
Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
-
Ekstrand, M.I.; Terzioglu, M.; Galter, D.; Zhu, S.; Hofstetter, C.; Lindqvist, E.; Thams, S.; Bergstrand, A.; Hansson, F.S.; Trifunovic, A.; et al.Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proc. Natl. Acad. Sci. USA 2007, 104, 1325-1330.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1325-1330
-
-
Ekstrand, M.I.1
Terzioglu, M.2
Galter, D.3
Zhu, S.4
Hofstetter, C.5
Lindqvist, E.6
Thams, S.7
Bergstrand, A.8
Hansson, F.S.9
Trifunovic, A.10
-
115
-
-
0035214256
-
Neurochemical findings in the MPTP model of Parkinson’s disease
-
Schmidt, N.; Ferger, B. Neurochemical findings in the MPTP model of Parkinson’s disease. J. Neural. Transm. 2001, 108, 1263-1282.
-
(2001)
J. Neural. Transm
, vol.108
, pp. 1263-1282
-
-
Schmidt, N.1
Ferger, B.2
-
116
-
-
84856293829
-
The molecular pathology of Alzheimer’s disease
-
Harrington, C.R. The molecular pathology of Alzheimer’s disease. Neuroimaging Clin. N. Am. 2012, 22, 11-22.
-
(2012)
Neuroimaging Clin. N. Am
, vol.22
, pp. 11-22
-
-
Harrington, C.R.1
-
117
-
-
79953208314
-
The role of the ubiquitin proteasome system in Alzheimer’s disease
-
Riederer, B.M.; Leuba, G.; Vernay, A.; Riederer, I.M. The role of the ubiquitin proteasome system in Alzheimer’s disease. Exp. Biol. Med.2011, 236, 268-276.
-
(2011)
Exp. Biol. Med
, vol.236
, pp. 268-276
-
-
Riederer, B.M.1
Leuba, G.2
Vernay, A.3
Riederer, I.M.4
-
118
-
-
84906666540
-
Mitochondrial dysfunction: Cause and consequence of Alzheimer’s disease
-
Friedland-Leuner, K.; Stockburger, C.; Denzer, I.; Eckert, G.P.; Müller, W.E. Mitochondrial dysfunction: Cause and consequence of Alzheimer’s disease. Prog. Mol. Biol. Transl. Sci. 2014, 127, 183-210.
-
(2014)
Prog. Mol. Biol. Transl. Sci
, vol.127
, pp. 183-210
-
-
Friedland-Leuner, K.1
Stockburger, C.2
Denzer, I.3
Eckert, G.P.4
Müller, W.E.5
-
119
-
-
84885625000
-
Natural compounds with anti-ageing activity
-
Argyropoulou, A.; Aligiannis, N.; Trougakos, I.P.; Skaltsounis, A.L. Natural compounds with anti-ageing activity. Nat. Prod. Rep. 2013, 30, 1412-1437.
-
(2013)
Nat. Prod. Rep
, vol.30
, pp. 1412-1437
-
-
Argyropoulou, A.1
Aligiannis, N.2
Trougakos, I.P.3
Skaltsounis, A.L.4
-
120
-
-
84903158901
-
The search for antiaging interventions: From elixirs to fasting regimens
-
De Cabo, R.; Carmona-Gutierrez, D.; Bernier, M.; Hall, M.N.; Madeo, F. The search for antiaging interventions: From elixirs to fasting regimens. Cell 2014, 157, 1515-1526.
-
(2014)
Cell
, vol.157
, pp. 1515-1526
-
-
De Cabo, R.1
Carmona-Gutierrez, D.2
Bernier, M.3
Hall, M.N.4
Madeo, F.5
-
121
-
-
0030830076
-
Fish intake and cardiovascular risk among middle-aged Japanese in Japan and Brazil
-
Mizushima, S.; Moriguchi, E.H.; Ishikawa, P.; Hekman, P.; Nara, Y.; Mimura, G.; Moriguchi, Y.; Yamori, Y. Fish intake and cardiovascular risk among middle-aged Japanese in Japan and Brazil. J. Cardiovasc. Risk 1997, 4, 191-199.
-
(1997)
J. Cardiovasc. Risk
, vol.4
, pp. 191-199
-
-
Mizushima, S.1
Moriguchi, E.H.2
Ishikawa, P.3
Hekman, P.4
Nara, Y.5
Mimura, G.6
Moriguchi, Y.7
Yamori, Y.8
-
122
-
-
79951715433
-
Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity
-
Huffman, K.M.; Slentz, C.A.; Bateman, L.A.; Thompson, D.; Muehlbauer, M.J.; Bain, J.R.; Stevens, R.D.; Wenner, B.R.; Kraus, V.B.; Newgard, C.B.; et al.Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity. Diabetes Care 2011, 34, 174-176.
-
(2011)
Diabetes Care
, vol.34
, pp. 174-176
-
-
Huffman, K.M.1
Slentz, C.A.2
Bateman, L.A.3
Thompson, D.4
Muehlbauer, M.J.5
Bain, J.R.6
Stevens, R.D.7
Wenner, B.R.8
Kraus, V.B.9
Newgard, C.B.10
|