Accumulation of basic amino acids at mitochondria dictates the cytotoxicity of aberrant ubiquitin

Cell Reports

Volumn 10, Issue 9, 2015, Pages 1557-1571

  Braun, RalfJ ^a   Sommer, Cornelia ^b,c   Leibiger, Christine ^a   Gentier, RominaJ G ^d   Dumit, VerónicaI ^e   Paduch, Katrin ^a   Eisenberg, Tobias ^b   Habernig, Lukas ^b   Trausinger, Gert ^f   Magnes, Christoph ^f   Pieber, Thomas ^f,g   Sinner, Frank ^f,g   Dengjel, Jörn ^e   vanLeeuwen, FredW ^d   Kroemer, Guido ^h,i,j,k   Madeo, Frank ^b,c  

^a UNIVERSITY OF BAYREUTH   (Germany)

^b UNIVERSITY OF GRAZ   (Austria)

^c BIOTECHMED GRAZ   (Austria)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF FREIBURG   (Germany)

^f JOANNEUM RESEARCH   (Austria)

^g MEDICAL UNIVERSITY OF GRAZ   (Austria)

^h INSERM   (France)

ⁱ INSTITUT GUSTAVE ROUSSY   (France)

^j HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^k UNIVERSITÉ PARIS DESCARTES   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CDC48 PROTEIN; LYSINE; MITOCHONDRIAL PROTEIN; ORNITHINE; PROTEASOME; RPN4 PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN; UBIQUITIN B; UNCLASSIFIED DRUG; VMS1 PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SYNTHESIS; APOPTOSIS; ARTICLE; BRAIN REGION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME INHIBITION; MITOCHONDRIAL STRESS; MITOCHONDRION; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; YEAST CELL;

EID: 84924589411     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.02.009     Document Type: Article

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