Soy Leaf Extract Containing Kaempferol Glycosides and Pheophorbides Improves Glucose Homeostasis by Enhancing Pancreatic β-Cell Function and Suppressing Hepatic Lipid Accumulation in db/db Mice

Journal of Agricultural and Food Chemistry

Volumn 63, Issue 32, 2015, Pages 7198-7210

  Li, Hua ^a   Ji, Hyeon Seon ^a,b   Kang, Ji Hyun ^a   Shin, Dong Ha ^c   Park, Ho Yong ^a,c   Choi, Myung Sook ^d   Lee, Chul Ho ^a   Lee, In Kyung ^e   Yun, Bong Sik ^e   Jeong, Tae Sook ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c College of Pharmacy Chungnam National University ^*  (South Korea)

^d Kyungpook National University   (South Korea)

^e Chonbuk National University   (South Korea)

Author keywords

glucose homeostasis; IRS; kaempferol; pheophorbide a; soy (Glycine max) leaf; SREBP 1

Indexed keywords

AMINO ACIDS; CELL PROLIFERATION; CELLS; CYTOLOGY; FLAVONOIDS; GLUCOSE; INSULIN; MAMMALS; MEDICAL PROBLEMS; PHYSIOLOGY; SUGARS;

GLUCOSE HOMEOSTASIS; GLYCINE MAX; IRS; KAEMPFEROL; PHEOPHORBIDE A; SREBP-1;

CELL SIGNALING;

GLYCINE MAX; MUS;

ANTIDIABETIC AGENT; CHLOROPHYLL; GLUCOSE; GLYCOSIDE; INSULIN; KAEMPFEROL; KAEMPFEROL DERIVATIVE; PLANT EXTRACT;

ANIMAL; C57BL MOUSE; CHEMISTRY; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; HUMAN; LIPID METABOLISM; LIVER; MALE; METABOLISM; MOUSE; PANCREAS ISLET BETA CELL; PLANT LEAF; SOYBEAN;

ANIMALS; CHLOROPHYLL; DIABETES MELLITUS, TYPE 2; GLUCOSE; GLYCOSIDES; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; KAEMPFEROLS; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; PLANT LEAVES; SOYBEANS;

EID: 84939801121     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b01639     Document Type: Article

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