Relative contributions of insulin resistance and β-cell dysfunction to the development of Type 2 diabetes in Koreans

Diabetic Medicine

Volumn 30, Issue 9, 2013, Pages 1075-1079

  Kim, C H ^a   Kim, H K ^b   Kim, E H ^b   Bae, S J ^b   Park, J Y ^c  

^a Soonchunhyang University College of Medicine   (South Korea)

^b Asan Medical Center   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CELL FUNCTION; DIET RESTRICTION; FAMILY HISTORY; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNORADIOMETRIC ASSAY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MEDICAL EXAMINATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; PATHOGENESIS; PHYSICAL ACTIVITY; PREVALENCE; QUESTIONNAIRE; SMOKING; WAIST CIRCUMFERENCE;

ADULT; AGED; BODY MASS INDEX; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; OVERWEIGHT; PREDIABETIC STATE; PREVALENCE; REPUBLIC OF KOREA; RISK FACTORS; YOUNG ADULT;

EID: 84882694110     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.12201     Document Type: Article

References (20)

1. Haffner SM, Kennedy E, Gonzalez C, Stern MP, Miettinen H. A prospective analysis of the HOMA model: The Mexico City Diabetes Study. Diabetes Care 1996; 19: 1138-1141.
2. Li CL, Tsai ST, Chou P. Relative role of insulin resistance and beta-cell dysfunction in the progression to type 2 diabetes-The Kinmen Study. Diabetes Res Clin Pract 2003; 59: 225-232.
3. Osei K, Rhinesmith S, Gaillard T, Schuster D. Impaired insulin sensitivity, insulin secretion, and glucose effectiveness predict future development of impaired glucose tolerance and type 2 diabetes in pre-diabetic African Americans: implications for primary diabetes prevention. Diabetes Care 2004; 27: 1439-1446.
4. Song Y, Manson JE, Tinker L, Howard BV, Kuller LH, Nathan L et al. Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study. Diabetes Care 2007; 30: 1747-1752.
5. Stancakova A, Javorsky M, Kuulasmaa T, Haffner SM, Kuusisto J, Laakso M. Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6414 Finnish men. Diabetes 2009; 58: 1212-1221.
6. Sung KC, Reaven GM, Kim SH. Utility of homeostasis model assessment of beta-cell function in predicting diabetes in 12 924 healthy Koreans. Diabetes Care 2010; 33: 200-202.
7. Kim DJ, Lee MS, Kim KW, Lee MK. Insulin secretory dysfunction and insulin resistance in the pathogenesis of Korean type 2 diabetes mellitus. Metabolism 2001; 50: 590-593.
8. Rhee SY, Chon S, Oh S, Kim SW, Kim JW, Kim YS et al. Insulin secretion and insulin resistance in newly diagnosed, drug naive prediabetes and type 2 diabetes patients with/without metabolic syndrome. Diabetes Res Clin Pract 2007; 76: 397-403.
9. Choi ES, Rhee EJ, Kim JH, Won JC, Park CY, Lee WY et al. Insulin sensitivity and insulin secretion determined by homeostasis model assessment and future risk of diabetes mellitus in Korean men. Korean Diabetes J 2008; 32: 498-505.
10. Rhee SY, Kim JY, Chon S, Hwang YC, Jeong IK, Oh S et al. The changes in early phase insulin secretion in newly diagnosed, drug naive Korean prediabetes subjects. Korean Diabetes J 2010; 34: 157-165.
11. Matsumoto K, Miyake S, Yano M, Ueki Y, Yamaguchi Y, Akazawa S et al. Glucose tolerance, insulin secretion, and insulin sensitivity in nonobese and obese Japanese subjects. Diabetes Care 1997; 20: 1562-1568.
12. Qian L, Xu L, Wang X, Fu X, Gu Y, Lin F et al. Early insulin secretion failure leads to diabetes in Chinese subjects with impaired glucose regulation. Diabetes Metab Res Rev 2009; 25: 144-149.
13. Kim DJ, Song KE, Park JW, Cho HK, Lee KW, Huh KB. Clinical characteristics of Korean type 2 diabetic patients in 2005. Diabetes Res Clin Pract 2007; 77: S252-257.
14. Rhee EJ, Choi JH, Yoo SH, Bae JC, Kim WJ, Choi ES et al. The association of unintentional changes in weight, body composition, and homeostasis model assessment index with glycemic progression in non-diabetic healthy subjects. Diabetes Metab J 2011; 35: 138-148.
15. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
16. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-1645.
17. Kim DJ. The epidemiology of diabetes in Korea. Diabetes Metab J 2011; 35: 303-308.
18. Haffner SM, Miettinen H, Stern MP. The homeostasis model in the San Antonio Heart Study. Diabetes Care 1997; 20: 1087-1092.
19. Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004; 27: 1487-1495.
20. Choi CS, Kim MY, Han K, Lee MS. Assessment of beta-cell function in human patients. Islets 2012; 4: 79-83.