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Volumn 19, Issue 11, 2014, Pages 18493-18510

Pterocarpan-enriched soy leaf extract ameliorates insulin sensitivity and pancreatic β-cell proliferation in type 2 diabetic mice

Author keywords

Glycine max; Insulin sensitivity; Pancreas; Pterocarpans; Type 2 diabetes

Indexed keywords

ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; PTEROCARPAN DERIVATIVE;

EID: 84912128254     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules191118493     Document Type: Article
Times cited : (30)

References (49)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw, J. E.; Sicree, R. A.; Zimmet, P. Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 2010, 87, 4-14.
    • (2010) Diabetes Res. Clin. Pract. , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 2
    • 75149130955 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 2010, 33, S62-S69.
    • (2010) Diabetes Care , vol.33 , pp. S62-S69
    • American Diabetes Association1
  • 3
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn, S. E.; Hull, R. L.; Utzschneider K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006, 444, 840-846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 5
    • 84861444859 scopus 로고    scopus 로고
    • Regulation of glucose transport by insulin: Traffic control of GLUT4
    • Leto, D.; Saltiel, A. R. Regulation of glucose transport by insulin: Traffic control of GLUT4. Nat. Rev. Mol. Cell Biol. 2012, 13, 383-396.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 383-396
    • Leto, D.1    Saltiel, A.R.2
  • 6
    • 24044468429 scopus 로고    scopus 로고
    • Turning signals on and off: GLUT4 traffic in the insulin-signaling highway
    • Thong, F. S.; Dugani, C. B.; Klip, A. Turning signals on and off: GLUT4 traffic in the insulin-signaling highway. Physiology 2005, 20, 271-284.
    • (2005) Physiology , vol.20 , pp. 271-284
    • Thong, F.S.1    Dugani, C.B.2    Klip, A.3
  • 7
    • 84866122780 scopus 로고    scopus 로고
    • Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
    • Copps, K. D.; White, M. F. Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia 2012, 55, 2565-2582.
    • (2012) Diabetologia , vol.55 , pp. 2565-2582
    • Copps, K.D.1    White, M.F.2
  • 8
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • Samuel, V. T.; Shulman, G. I. Mechanisms for insulin resistance: Common threads and missing links. Cell 2012, 148, 852-871.
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 9
    • 0025770650 scopus 로고
    • The role of soy products in reducing risk of cancer
    • Messina, M.; Barnes, S. The role of soy products in reducing risk of cancer. J. Natl. Cancer Inst. 1991, 83, 541-546.
    • (1991) J. Natl. Cancer Inst. , vol.83 , pp. 541-546
    • Messina, M.1    Barnes, S.2
  • 10
    • 38049074972 scopus 로고    scopus 로고
    • Epidemiology of soy exposures and breast cancer risk
    • Wu, A. H.; Yu, M. C.; Tseng, C. C.; Pike, M. C. Epidemiology of soy exposures and breast cancer risk. Br. J. Cancer 2008, 98, 9-14.
    • (2008) Br. J. Cancer , vol.98 , pp. 9-14
    • Wu, A.H.1    Yu, M.C.2    Tseng, C.C.3    Pike, M.C.4
  • 11
    • 0031917223 scopus 로고    scopus 로고
    • Decreased serum total cholesterol concentration is associated with high intake of soy products in Japanese men and women
    • Nagata, C.; Takatsuka, N.; Kurisu, Y.; Shimizu, H. Decreased serum total cholesterol concentration is associated with high intake of soy products in Japanese men and women. J. Nutr. 1998, 128, 209-213.
    • (1998) J. Nutr. , vol.128 , pp. 209-213
    • Nagata, C.1    Takatsuka, N.2    Kurisu, Y.3    Shimizu, H.4
  • 14
    • 33645050957 scopus 로고    scopus 로고
    • Soy protein, isoflavones, and cardiovascular health: An American Heart Association Science Advisory for professionals from the Nutrition Committee
    • Sacks, F. M.; Lichtenstein, A.; van Horn, L.; Harris, W.; Kris-Etherton, P.; Winston, M. Soy protein, isoflavones, and cardiovascular health: An American Heart Association Science Advisory for professionals from the Nutrition Committee. Circulation 2006, 113, 1034-1044.
    • (2006) Circulation , vol.113 , pp. 1034-1044
    • Sacks, F.M.1    Lichtenstein, A.2    Van Horn, L.3    Harris, W.4    Kris-Etherton, P.5    Winston, M.6
  • 15
    • 50349093170 scopus 로고    scopus 로고
    • Enzymatic preparation of immunomodulating hydrolysates from soy proteins
    • Kong, X.; Guo, M.; Hua, Y.; Cao, D.; Zhang, C. Enzymatic preparation of immunomodulating hydrolysates from soy proteins. Bioresour. Technol. 2008, 99, 8873-8879.
    • (2008) Bioresour. Technol. , vol.99 , pp. 8873-8879
    • Kong, X.1    Guo, M.2    Hua, Y.3    Cao, D.4    Zhang, C.5
  • 16
    • 80051571602 scopus 로고    scopus 로고
    • Immunomodulatory bioactivity of soy and milk ferments on monocyte and macrophage models
    • Masotti, A. I.; Buckley, N.; Champagne, C. P.; Green-Johnson, J. Immunomodulatory bioactivity of soy and milk ferments on monocyte and macrophage models. Food Res. Int. 2011, 44, 2475-2481.
    • (2011) Food Res. Int. , vol.44 , pp. 2475-2481
    • Masotti, A.I.1    Buckley, N.2    Champagne, C.P.3    Green-Johnson, J.4
  • 17
    • 0031741906 scopus 로고    scopus 로고
    • Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones
    • Setchell, K. D. Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones. Am. J. Clin. Nutr. 1998, 68, 1333S-1346S.
    • (1998) Am. J. Clin. Nutr. , vol.68 , pp. 1333S-1346S
    • Setchell, K.D.1
  • 18
  • 19
    • 78751580538 scopus 로고    scopus 로고
    • The most abundant polyphenol of soy leaves, coumestrol, displays potent α-glucosidase inhibitory activity
    • Yuk, H. J.; Lee, J. H.; Curtis-Long, M. J.; Lee, J. W.; Kim, Y. S.; Ryu, H. W.; Park, C. G.; Jeong, T. S.; Park, K. H. The most abundant polyphenol of soy leaves, coumestrol, displays potent α-glucosidase inhibitory activity. Food Chem. 2011, 126, 1057-1063.
    • (2011) Food Chem. , vol.126 , pp. 1057-1063
    • Yuk, H.J.1    Lee, J.H.2    Curtis-Long, M.J.3    Lee, J.W.4    Kim, Y.S.5    Ryu, H.W.6    Park, C.G.7    Jeong, T.S.8    Park, K.H.9
  • 21
    • 83055196876 scopus 로고    scopus 로고
    • Pterocarpan profiles for soybean leaves at different growth stages and investigation of their glycosidase inhibitions
    • Yuk, H. J., Curtis-Long, M. J., Ryu, H. W.; Jang, K. C.; Seo, W. D.; Kim, J. Y.; Kang, K. Y.; Park, K. H. Pterocarpan profiles for soybean leaves at different growth stages and investigation of their glycosidase inhibitions. J. Agric. Food Chem. 2011, 59, 12683-12690.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 12683-12690
    • Yuk, H.J.1    Curtis-Long, M.J.2    Ryu, H.W.3    Jang, K.C.4    Seo, W.D.5    Kim, J.Y.6    Kang, K.Y.7    Park, K.H.8
  • 22
    • 84898056846 scopus 로고    scopus 로고
    • Activity of three cytotoxic isoflavonoids from Erythrina excelsa and Erythrina senegalensis (neobavaisoflavone, sigmoidin H and isoneorautenol) toward multi-factorial drug resistant cancer cells
    • Kuete, V.; Sandjo, L. P.; Kwamou, G. M.; Wiench, B.; Nkengfack, A. E.; Efferth, T. Activity of three cytotoxic isoflavonoids from Erythrina excelsa and Erythrina senegalensis (neobavaisoflavone, sigmoidin H and isoneorautenol) toward multi-factorial drug resistant cancer cells. Phytomedicine 2014, 21, 682-688.
    • (2014) Phytomedicine , vol.21 , pp. 682-688
    • Kuete, V.1    Sandjo, L.P.2    Kwamou, G.M.3    Wiench, B.4    Nkengfack, A.E.5    Efferth, T.6
  • 23
    • 84883254841 scopus 로고    scopus 로고
    • Coumestrol from the national cancer Institute's natural product library is a novel inhibitor of protein kinase CK2
    • Liu, S.; Hsieh, D.; Yang, Y. L.; Xu, Z.; Peto, C.; Jablons, D. M.; You, L. Coumestrol from the national cancer Institute's natural product library is a novel inhibitor of protein kinase CK2. BMC Pharmacol. Toxicol. 2013, 11, 14-36.
    • (2013) BMC Pharmacol. Toxicol. , vol.11 , pp. 14-36
    • Liu, S.1    Hsieh, D.2    Yang, Y.L.3    Xu, Z.4    Peto, C.5    Jablons, D.M.6    You, L.7
  • 24
    • 84885359067 scopus 로고    scopus 로고
    • Phytoestrogens mediated anti-inflammatory effect through suppression of IRF-1 and pSTAT1 expressions in lipopolysaccharide-activated microglia
    • Jantaratnotai, N.; Utaisincharoen, P.; Sanvarinda, P.; Thampithak, A.; Sanvarinda, Y. Phytoestrogens mediated anti-inflammatory effect through suppression of IRF-1 and pSTAT1 expressions in lipopolysaccharide-activated microglia. Int. Immunopharmacol. 2013, 17, 483-488.
    • (2013) Int. Immunopharmacol. , vol.17 , pp. 483-488
    • Jantaratnotai, N.1    Utaisincharoen, P.2    Sanvarinda, P.3    Thampithak, A.4    Sanvarinda, Y.5
  • 25
    • 78149237932 scopus 로고    scopus 로고
    • D-chiro-inositol glycans in insulin signaling and insulin resistance
    • Larner, J.; Brautigan, D. L.; Thorner, M. O. D-chiro-inositol glycans in insulin signaling and insulin resistance. Mol. Med. 2010, 16, 543-552.
    • (2010) Mol. Med. , vol.16 , pp. 543-552
    • Larner, J.1    Brautigan, D.L.2    Thorner, M.O.3
  • 26
    • 84899905701 scopus 로고    scopus 로고
    • Islet number rather than silet is a major determinant of β-cell and α-cell mass in humans
    • Kou, K.; Saisho, Y.; Sato, S.; Yamada, T.; Itoh, H. Islet number rather than silet is a major determinant of β-cell and α-cell mass in humans. J. Clin. Endocrinol. Metab. 2014, 99, 1733-1740.
    • (2014) J. Clin. Endocrinol. Metab. , vol.99 , pp. 1733-1740
    • Kou, K.1    Saisho, Y.2    Sato, S.3    Yamada, T.4    Itoh, H.5
  • 27
    • 77956373690 scopus 로고    scopus 로고
    • Beta-cell failure in diet-induced obese mice stratified according to body weight gain: Secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass
    • Peyot, M. L.; Pepin, E.; Lamontagne, J.; Latour, M. G.; Zarrouki, B.; Lussier, R.; Pineda, M.; Jetton, T. L.; Madiraju, S. R.; Joly, E.; et al. Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes 2010, 59, 2178-2187.
    • (2010) Diabetes , vol.59 , pp. 2178-2187
    • Peyot, M.L.1    Pepin, E.2    Lamontagne, J.3    Latour, M.G.4    Zarrouki, B.5    Lussier, R.6    Pineda, M.7    Jetton, T.L.8    Madiraju, S.R.9    Joly, E.10
  • 28
    • 84903287206 scopus 로고    scopus 로고
    • The beneficial effect of soybean (Glycine max (L.) Merr.) leaf extracts in adults with prediabetes: A randomized placebo controlled trial
    • Choi, M. S.; Ryu, R.; Seo, Y. R.; Jeong, T. S.; Shin, D. H.; Park, Y. B.; Kim, S. R.; Jung, U. J. The beneficial effect of soybean (Glycine max (L.) Merr.) leaf extracts in adults with prediabetes: A randomized placebo controlled trial. Food Funct. 2014, 25, 1621-1630.
    • (2014) Food Funct. , vol.25 , pp. 1621-1630
    • Choi, M.S.1    Ryu, R.2    Seo, Y.R.3    Jeong, T.S.4    Shin, D.H.5    Park, Y.B.6    Kim, S.R.7    Jung, U.J.8
  • 29
    • 80053175452 scopus 로고    scopus 로고
    • Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: A randomized control trial
    • Kim, J. E.; Jeon, S. M.; Park, K. H.; Lee, W. S.; Jeong, T. S.; McGregor, R. A.; Choi, M. S. Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial. Nutr. J. 2011, 10, 94.
    • (2011) Nutr. J. , vol.10 , pp. 94
    • Kim, J.E.1    Jeon, S.M.2    Park, K.H.3    Lee, W.S.4    Jeong, T.S.5    McGregor, R.A.6    Choi, M.S.7
  • 30
    • 84908606765 scopus 로고    scopus 로고
    • In vitro quantitative and relative gene expression analysis of pancreatic transcription factors Pdx-1, Ngn-3, Isl-1, Pax-4, Pax-6 and Nkx-6.1 in trans-differentiated human hepatic progenitors
    • Vishwakarma, S. K.; Rahamathulla, S.; Bardia, A.; Tiwari, S. K.; Srinivas, G.; Raj, A.; Tripura, C.; Sandhya, A.; Habeeb, M. A.; Khan, A. A.; et al. In vitro quantitative and relative gene expression analysis of pancreatic transcription factors Pdx-1, Ngn-3, Isl-1, Pax-4, Pax-6 and Nkx-6.1 in trans-differentiated human hepatic progenitors. J. Diabetes Investig. 2014, 5, 492-500.
    • (2014) J. Diabetes Investig. , vol.5 , pp. 492-500
    • Vishwakarma, S.K.1    Rahamathulla, S.2    Bardia, A.3    Tiwari, S.K.4    Srinivas, G.5    Raj, A.6    Tripura, C.7    Sandhya, A.8    Habeeb, M.A.9    Khan, A.A.10
  • 37
    • 50949083865 scopus 로고    scopus 로고
    • Antihyperlipidemic effect of D-pinitol on streptozotocin-induced diabetic Wistar rats
    • Geethan, P. K.; Prince, P. S. Antihyperlipidemic effect of D-pinitol on streptozotocin-induced diabetic Wistar rats. J. Biochem. Mol. Toxicol. 2008, 22, 220-224.
    • (2008) J. Biochem. Mol. Toxicol. , vol.22 , pp. 220-224
    • Geethan, P.K.1    Prince, P.S.2
  • 38
    • 15544372512 scopus 로고    scopus 로고
    • Effects of pinitol isolated from soybeans on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: A randomized controlled study
    • Kim, J. I.; Kim, J. C.; Kang, M. J.; Lee, M. S.; Kim, J. J.; Cha, I. J. Effects of pinitol isolated from soybeans on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: a randomized controlled study. Eur. J. Clin. Nutr. 2005, 59, 456-458.
    • (2005) Eur. J. Clin. Nutr. , vol.59 , pp. 456-458
    • Kim, J.I.1    Kim, J.C.2    Kang, M.J.3    Lee, M.S.4    Kim, J.J.5    Cha, I.J.6
  • 39
    • 77956174464 scopus 로고    scopus 로고
    • Impact of D-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats
    • Sivakumar, S.; Palsamy, P.; Subramanian, S. P. Impact of D-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats. Chem. Biol. Interact. 2010, 188, 237-245.
    • (2010) Chem. Biol. Interact. , vol.188 , pp. 237-245
    • Sivakumar, S.1    Palsamy, P.2    Subramanian, S.P.3
  • 40
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signaling and the regulation of glucose and lipid metabolism
    • Saltiel, A. R.; Kahn, C. R. Insulin signaling and the regulation of glucose and lipid metabolism. Nature 2001, 414, 799-806.
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 41
    • 79951962147 scopus 로고    scopus 로고
    • CREB and the CRTC co-activators: Sensors for hormonal and metabolic signals
    • Altarejos, J. Y.; Montminy, M. CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat. Rev. Mol. Cell Biol. 2011, 12, 141-151.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 141-151
    • Altarejos, J.Y.1    Montminy, M.2
  • 42
    • 30044452201 scopus 로고    scopus 로고
    • The tangled path to glucose production
    • Matsumoto, M.; Accili, D. The tangled path to glucose production. Nat. Med. 2006, 12, 33-34.
    • (2006) Nat. Med. , vol.12 , pp. 33-34
    • Matsumoto, M.1    Accili, D.2
  • 43
    • 83555166240 scopus 로고    scopus 로고
    • Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis
    • Jitrapakdee, S. Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis. Int. J. Biochem. Cell Biol. 2012, 44, 33-45.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 33-45
    • Jitrapakdee, S.1
  • 44
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky, J. M.; Glass, C. K. Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 2010, 72, 219-246.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 46
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • Donath, M. Y.; Shoelson, S. E. Type 2 diabetes as an inflammatory disease. Nat. Rev. Immunol. 2011, 11, 98-107.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 47
    • 33644755633 scopus 로고    scopus 로고
    • Interleukin-6 and diabetes: The good, the bad, or the indifferent?
    • Kristiansen, O. P.; Mandrup-Poulsen, T. Interleukin-6 and diabetes: The good, the bad, or the indifferent? Diabetes 2005, 54, S114-S124.
    • (2005) Diabetes , vol.54 , pp. S114-S124
    • Kristiansen, O.P.1    Mandrup-Poulsen, T.2
  • 48
    • 31444452629 scopus 로고    scopus 로고
    • Macrophage-secreted factors induce adipocyte inflammation and insulin resistance
    • Permana, P. A.; Menge, C.; Reaven, P. D. Macrophage-secreted factors induce adipocyte inflammation and insulin resistance. Biochem. Biophys. Res. Commun. 2006, 341, 507-514.
    • (2006) Biochem. Biophys. Res. Commun. , vol.341 , pp. 507-514
    • Permana, P.A.1    Menge, C.2    Reaven, P.D.3
  • 49
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews, D. R.; Hosker, J. P.; Rudenski, A. S.; Naylor, B. A.; Treacher D. F.; Turner, R. C. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28, 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6


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