메뉴 건너뛰기




Volumn 37, Issue 9, 2015, Pages 1005-1015

Noncoding RNAs and chronic inflammation: Micro-managing the fire within

Author keywords

Aging; Autoimmunity; Chronic inflammation; MiRNAs; Noncoding RNA

Indexed keywords

ANTIGEN; MICRORNA; UNTRANSLATED RNA; BIOLOGICAL MARKER;

EID: 84939650575     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201500054     Document Type: Review
Times cited : (26)

References (121)
  • 1
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. 2008. Origin and physiological roles of inflammation. Nature 454: 428-35.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 2
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity- related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, et al. 2003. Chronic inflammation in fat plays a crucial role in the development of obesity- related insulin resistance. J Clin Invest 112: 1821-30.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4
  • 3
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflammation in rheumatoid arthritis
    • Choy EH, Panayi GS. 2001. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 344: 907-16.
    • (2001) N Engl J Med , vol.344 , pp. 907-916
    • Choy, E.H.1    Panayi, G.S.2
  • 4
    • 0142009533 scopus 로고    scopus 로고
    • Development of autoantibodies before the clinical onset of systemic lupus erythematosus
    • Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, et al. 2003. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 349: 1526-33.
    • (2003) N Engl J Med , vol.349 , pp. 1526-1533
    • Arbuckle, M.R.1    McClain, M.T.2    Rubertone, M.V.3    Scofield, R.H.4
  • 5
    • 3142514201 scopus 로고    scopus 로고
    • Protein aggregation and neurodegenerative disease
    • Ross CA, Poirier MA. 2004. Protein aggregation and neurodegenerative disease. Nat Med 10: 10-7.
    • (2004) Nat Med , vol.10 , pp. 10-17
    • Ross, C.A.1    Poirier, M.A.2
  • 6
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, Maseri A. 2002. Inflammation and atherosclerosis. Circulation 105: 1135-43.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 7
    • 15244348518 scopus 로고    scopus 로고
    • The origins of age-related proinflammatory state
    • Ferrucci L, Corsi A, Lauretani F, Bandinelli S, et al. 2005. The origins of age-related proinflammatory state. Blood 105: 2294-9.
    • (2005) Blood , vol.105 , pp. 2294-2299
    • Ferrucci, L.1    Corsi, A.2    Lauretani, F.3    Bandinelli, S.4
  • 8
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4: 330-6.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 9
    • 0025889028 scopus 로고
    • IL-10 inhibits cytokine production by activated macrophages
    • Fiorentino DF, Zlotnik A, Mosmann TR, Howard M, et al. 1991. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147: 3815-22.
    • (1991) J. Immunol. , vol.147 , pp. 3815-3822
    • Fiorentino, D.F.1    Zlotnik, A.2    Mosmann, T.R.3    Howard, M.4
  • 10
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. 2004. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22: 531-62.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 11
    • 0034730713 scopus 로고    scopus 로고
    • Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
    • Lee EG, Boone DL, Chai S, Libby SL, et al. 2000. Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science 289: 2350-4.
    • (2000) Science , vol.289 , pp. 2350-2354
    • Lee, E.G.1    Boone, D.L.2    Chai, S.3    Libby, S.L.4
  • 12
    • 34250357688 scopus 로고    scopus 로고
    • Resolvin E1 and protectin D1 activate inflammation-resolution programmes
    • Schwab JM, Chiang N, Arita M, Serhan CN. 2007. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447: 869-74.
    • (2007) Nature , vol.447 , pp. 869-874
    • Schwab, J.M.1    Chiang, N.2    Arita, M.3    Serhan, C.N.4
  • 13
    • 53749094183 scopus 로고    scopus 로고
    • CTLA-4 control over Foxp3+ regulatory T cell function
    • Wing K, Onishi Y, Prieto- Martin P, Yamaguchi T, et al. 2008. CTLA-4 control over Foxp3+ regulatory T cell function. Science 322: 271-5.
    • (2008) Science , vol.322 , pp. 271-275
    • Wing, K.1    Onishi, Y.2    Prieto-Martin, P.3    Yamaguchi, T.4
  • 14
    • 0025225333 scopus 로고
    • Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
    • Ohlsson K, Björk P, Bergenfeldt M, Hageman R, et al. 1990. Interleukin-1 receptor antagonist reduces mortality from endotoxin shock. Nature 348: 550-2.
    • (1990) Nature , vol.348 , pp. 550-552
    • Ohlsson, K.1    Björk, P.2    Bergenfeldt, M.3    Hageman, R.4
  • 15
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, Robert C, Daud A, Hodi FS, et al. 2013. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 369: 134-44.
    • (2013) N Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3    Hodi, F.S.4
  • 16
    • 0034879613 scopus 로고    scopus 로고
    • Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease
    • Schaller M, Burton DR, Ditzel HJ. 2001. Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease. Nat Immunol 2: 746-53.
    • (2001) Nat Immunol , vol.2 , pp. 746-753
    • Schaller, M.1    Burton, D.R.2    Ditzel, H.J.3
  • 17
    • 78149360607 scopus 로고    scopus 로고
    • Autoimmunity and chronic inflammation-two clearance-related steps in the etiopathogenesis of SLE
    • Muñoz LE, Janko C, Schulze C, Schorn C, et al. 2010. Autoimmunity and chronic inflammation-two clearance-related steps in the etiopathogenesis of SLE. Autoimmun Rev 10: 38-42.
    • (2010) Autoimmun Rev , vol.10 , pp. 38-42
    • Muñoz, L.E.1    Janko, C.2    Schulze, C.3    Schorn, C.4
  • 18
    • 0032950794 scopus 로고    scopus 로고
    • Identification of autoantibodies associated with myelin damage in multiple sclerosis
    • Genain CP, Cannella B, Hauser SL, Raine CS. 1999. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med 5: 170-5.
    • (1999) Nat Med , vol.5 , pp. 170-175
    • Genain, C.P.1    Cannella, B.2    Hauser, S.L.3    Raine, C.S.4
  • 19
    • 0032495536 scopus 로고    scopus 로고
    • Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes
    • Wilson SB, Kent SC, Patton KT, Orban T, et al. 1998. Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature 391: 177-81.
    • (1998) Nature , vol.391 , pp. 177-181
    • Wilson, S.B.1    Kent, S.C.2    Patton, K.T.3    Orban, T.4
  • 20
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • Bianchi ME. 2007. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81: 1-5.
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 21
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, Murano I, et al. 2005. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 46: 2347-55.
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3    Murano, I.4
  • 22
    • 0024501678 scopus 로고
    • High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies
    • Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, et al. 1989. High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation 79: 8-16.
    • (1989) Circulation , vol.79 , pp. 8-16
    • Gordon, D.J.1    Probstfield, J.L.2    Garrison, R.J.3    Neaton, J.D.4
  • 24
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, et al. 2006. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444: 1027-31.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4
  • 26
    • 33749137515 scopus 로고    scopus 로고
    • A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
    • De Bakker PIW, McVean G, Sabeti PC, Miretti MM, et al. 2006. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet 38: 1166-72.
    • (2006) Nat Genet , vol.38 , pp. 1166-1172
    • De Bakker, P.I.W.1    McVean, G.2    Sabeti, P.C.3    Miretti, M.M.4
  • 27
    • 0035555022 scopus 로고    scopus 로고
    • The genetics of complex autoimmune diseases: non-MHC susceptibility genes
    • Wandstrat A, Wakeland E. 2001. The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nat Immunol 2: 802-9.
    • (2001) Nat Immunol , vol.2 , pp. 802-809
    • Wandstrat, A.1    Wakeland, E.2
  • 28
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • Mevorach D, Zhou JL, Song X, Elkon KB. 1998. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med 188: 387-92.
    • (1998) J Exp Med , vol.188 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 29
    • 0034773019 scopus 로고    scopus 로고
    • Mechanisms for the induction of autoimmunity by infectious agents
    • Wucherpfennig KW. 2001. Mechanisms for the induction of autoimmunity by infectious agents. J Clin Invest 108: 1097-104.
    • (2001) J Clin Invest , vol.108 , pp. 1097-1104
    • Wucherpfennig, K.W.1
  • 30
    • 0024785684 scopus 로고
    • Molecular mimicry and lyme borreliosis: a shared antigenic determinant between Borrelia burgdorferi and human tissue
    • Aberer E, Brunner C, Suchanek G, Klade H, et al. 1989. Molecular mimicry and lyme borreliosis: a shared antigenic determinant between Borrelia burgdorferi and human tissue. Ann Neurol 26: 732-7.
    • (1989) Ann Neurol , vol.26 , pp. 732-737
    • Aberer, E.1    Brunner, C.2    Suchanek, G.3    Klade, H.4
  • 31
    • 0031923273 scopus 로고    scopus 로고
    • Clearance of Borrelia burgdorferi may not be required for resistance to experimental lyme arthritis
    • Brown CR, Reiner SL. 1998. Clearance of Borrelia burgdorferi may not be required for resistance to experimental lyme arthritis. Infect Immun 66: 2065-71.
    • (1998) Infect Immun , vol.66 , pp. 2065-2071
    • Brown, C.R.1    Reiner, S.L.2
  • 32
    • 77952172555 scopus 로고    scopus 로고
    • A role for human endogenous retrovirus-K (HML-2) in rheumatoid arthritis: investigating mechanisms of pathogenesis
    • Freimanis G, Hooley P, Ejtehadi HD, Ali HA, et al. 2010. A role for human endogenous retrovirus-K (HML-2) in rheumatoid arthritis: investigating mechanisms of pathogenesis. Clin Exp Immunol 160: 340-7.
    • (2010) Clin Exp Immunol , vol.160 , pp. 340-347
    • Freimanis, G.1    Hooley, P.2    Ejtehadi, H.D.3    Ali, H.A.4
  • 33
    • 84866741091 scopus 로고    scopus 로고
    • Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease
    • Perron H, Germi R, Bernard C, Garcia-Montojo M, et al. 2012. Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease. Mult Scler J 12: 1721-36.
    • (2012) Mult Scler J , vol.12 , pp. 1721-1736
    • Perron, H.1    Germi, R.2    Bernard, C.3    Garcia-Montojo, M.4
  • 34
    • 0030066393 scopus 로고    scopus 로고
    • Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease
    • Urnovitz HB, Murphy WH. 1996. Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease. Clin Microbiol Rev 9: 72-99.
    • (1996) Clin Microbiol Rev , vol.9 , pp. 72-99
    • Urnovitz, H.B.1    Murphy, W.H.2
  • 35
    • 37349021003 scopus 로고    scopus 로고
    • Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications
    • Tabas I, Williams KJ, Borén J. 2007. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation 116: 1832-44.
    • (2007) Circulation , vol.116 , pp. 1832-1844
    • Tabas, I.1    Williams, K.J.2    Borén, J.3
  • 36
    • 77949848854 scopus 로고    scopus 로고
    • Prion-like transmission of protein aggregates in neurodegenerative diseases
    • Yvette G. 2010. Prion-like transmission of protein aggregates in neurodegenerative diseases. Nat Rev Mol Cell Biol 11: 301-7.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 301-307
    • Yvette, G.1
  • 37
    • 77952303410 scopus 로고    scopus 로고
    • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
    • Allen IC, TeKippe EM, Woodford R-MT, Uronis JM, et al. 2010. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med 207: 1045-56.
    • (2010) J Exp Med , vol.207 , pp. 1045-1056
    • Allen, I.C.1    TeKippe, E.M.2    Woodford, R.-M.3    Uronis, J.M.4
  • 39
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders 1
    • Hotamisligil GS. 2006. Inflammation and metabolic disorders 1. Nature 444: 860-7.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 40
    • 84857100496 scopus 로고    scopus 로고
    • Gut microbiota, immunity, and disease: a complex relationship
    • Kosiewicz MM, Zirnheld AL, Alard P. 2011. Gut microbiota, immunity, and disease: a complex relationship. Front Microbiol 2: 1-11.
    • (2011) Front Microbiol , vol.2 , pp. 1-11
    • Kosiewicz, M.M.1    Zirnheld, A.L.2    Alard, P.3
  • 41
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round JL, Mazmanian SK. 2009. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9: 313-23.
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 42
    • 78449296237 scopus 로고    scopus 로고
    • Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors
    • Benson AK, Kelly SA, Legge R, Ma F, et al. 2010. Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors. Proc Natl Acad Sci USA 107: 18933-8.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 18933-18938
    • Benson, A.K.1    Kelly, S.A.2    Legge, R.3    Ma, F.4
  • 44
    • 0033962638 scopus 로고    scopus 로고
    • Changes in the B-cell repertoire with age
    • Weksler ME. 2000. Changes in the B-cell repertoire with age. Vaccine 18: 1624-8.
    • (2000) Vaccine , vol.18 , pp. 1624-1628
    • Weksler, M.E.1
  • 45
    • 33744996006 scopus 로고    scopus 로고
    • Why aging T cells fail: implications for vaccination
    • Haynes L, Swain SL. 2006. Why aging T cells fail: implications for vaccination. Immunity 24: 663-6.
    • (2006) Immunity , vol.24 , pp. 663-666
    • Haynes, L.1    Swain, S.L.2
  • 46
    • 84876909069 scopus 로고    scopus 로고
    • The ageing haematopoietic stem cell compartment
    • Geiger H, de Haan G, Florian MC. 2013. The ageing haematopoietic stem cell compartment. Nat Rev Immunol 13: 376-89.
    • (2013) Nat Rev Immunol , vol.13 , pp. 376-389
    • Geiger, H.1    de Haan, G.2    Florian, M.C.3
  • 47
    • 77953854915 scopus 로고    scopus 로고
    • Leukocyte function in the aging immune system
    • Desai A, Grolleau-Julius A, Yung R. 2010. Leukocyte function in the aging immune system. J Leukoc Biol 87: 1001-9.
    • (2010) J Leukoc Biol , vol.87 , pp. 1001-1009
    • Desai, A.1    Grolleau-Julius, A.2    Yung, R.3
  • 48
    • 0027438710 scopus 로고
    • Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
    • Elliott MJ, Maini RN, Feldmann M, Long-Fox A, et al. 1993. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 36: 1681-90.
    • (1993) Arthritis Rheum , vol.36 , pp. 1681-1690
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Long-Fox, A.4
  • 49
    • 34047174085 scopus 로고    scopus 로고
    • A pilot study of IL-1 inhibition by anakinra in acute gout
    • So A, De Smedt T, Revaz S, Tschopp J. 2007. A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther 9: R28.
    • (2007) Arthritis Res Ther , vol.9 , pp. R28
    • So, A.1    De Smedt, T.2    Revaz, S.3    Tschopp, J.4
  • 50
    • 0025757275 scopus 로고
    • Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody
    • McIntyre KW, Stepan GJ, Kolinsky KD, Benjamin WR, et al. 1991. Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody. J Exp Med 173: 931-9.
    • (1991) J Exp Med , vol.173 , pp. 931-939
    • McIntyre, K.W.1    Stepan, G.J.2    Kolinsky, K.D.3    Benjamin, W.R.4
  • 51
    • 33744477341 scopus 로고    scopus 로고
    • How corticosteroids control inflammation: Quintiles Prize Lecture 2005
    • Barnes PJ. 2006. How corticosteroids control inflammation: Quintiles Prize Lecture 2005. Br J Pharmacol 148: 245-54.
    • (2006) Br J Pharmacol , vol.148 , pp. 245-254
    • Barnes, P.J.1
  • 52
    • 58149085504 scopus 로고    scopus 로고
    • MicroRNA control in the immune system: basic principles
    • Xiao C, Rajewsky K. 2009. MicroRNA control in the immune system: basic principles. Cell 136: 26-36.
    • (2009) Cell , vol.136 , pp. 26-36
    • Xiao, C.1    Rajewsky, K.2
  • 53
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D. 2010. Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 10: 111-22.
    • (2010) Nat Rev Immunol , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 54
    • 84922532533 scopus 로고    scopus 로고
    • Long non-coding RNAs in the regulation of the immune response
    • Heward JA, Lindsay MA. 2014. Long non-coding RNAs in the regulation of the immune response. Trends Immunol 35: 408-19.
    • (2014) Trends Immunol , vol.35 , pp. 408-419
    • Heward, J.A.1    Lindsay, M.A.2
  • 55
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-54.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 56
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, et al. 2004. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101: 2999-3004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4
  • 57
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J, Konishi H, Yanagisawa K, Tomida S, et al. 2004. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64: 3753-6.
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3    Tomida, S.4
  • 58
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: small RNAs with a big role in gene regulation
    • He L, Hannon GJ. 2004. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-31.
    • (2004) Nat Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 59
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. 2004. The functions of animal microRNAs. Nature 431: 350-5.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 60
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • Ebert MS, Sharp PA. 2012. Roles for microRNAs in conferring robustness to biological processes. Cell 149: 505-24.
    • (2012) Cell , vol.149 , pp. 505-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 61
    • 33747608638 scopus 로고    scopus 로고
    • NF-kB-dependent induction of miR-146a, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang K, Baltimore D. 2006. NF-kB-dependent induction of miR-146a, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 33: 6-11.
    • (2006) Proc Natl Acad Sci USA , vol.33 , pp. 6-11
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.3    Baltimore, D.4
  • 63
    • 84920983137 scopus 로고    scopus 로고
    • miR-155 augments CD8+T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γ c cytokines
    • Ji Y, Wrzesinski C, Yu Z, Hu J, et al. 2015. miR-155 augments CD8+T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γ c cytokines. Proc Natl Acad Sci USA 112: 476-81.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 476-481
    • Ji, Y.1    Wrzesinski, C.2    Yu, Z.3    Hu, J.4
  • 64
    • 33947721625 scopus 로고    scopus 로고
    • miR-181a is an intrinsic modulator of T cell sensitivity and selection
    • Li QJ, Chau J, Ebert PJR, Sylvester G, et al. 2007. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129: 147-61.
    • (2007) Cell , vol.129 , pp. 147-161
    • Li, Q.J.1    Chau, J.2    Ebert, P.J.R.3    Sylvester, G.4
  • 65
    • 84880767787 scopus 로고    scopus 로고
    • MicroRNAs of the miR-17~92 family are critical regulators of T(FH) differentiation
    • Kang SG, Liu W-H., Lu P, Jin HY, et al. 2013. MicroRNAs of the miR-17~92 family are critical regulators of T(FH) differentiation. Nat Immunol 14: 849-57.
    • (2013) Nat Immunol , vol.14 , pp. 849-857
    • Kang, S.G.1    Liu, W.-H.2    Lu, P.3    Jin, H.Y.4
  • 66
    • 84879123259 scopus 로고    scopus 로고
    • MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expression
    • Hu R, Huffaker TB, Kagele DA, Runtsch MC, et al. 2013. MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expression. J Immunol 190: 5972-80.
    • (2013) J Immunol , vol.190 , pp. 5972-5980
    • Hu, R.1    Huffaker, T.B.2    Kagele, D.A.3    Runtsch, M.C.4
  • 67
    • 84902682101 scopus 로고    scopus 로고
    • MiR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve Polycomb-mediated repression
    • Escobar TM, Kanellopoulou C, Kugler DG, Kilaru G, et al. 2014. MiR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve Polycomb-mediated repression. Immunity 40: 865-79.
    • (2014) Immunity , vol.40 , pp. 865-879
    • Escobar, T.M.1    Kanellopoulou, C.2    Kugler, D.G.3    Kilaru, G.4
  • 68
    • 84908146717 scopus 로고    scopus 로고
    • miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation
    • Hu R, Kagele DA, Huffaker TB, Runtsch MC, et al. 2014. miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. Immunity 41: 605-19.
    • (2014) Immunity , vol.41 , pp. 605-619
    • Hu, R.1    Kagele, D.A.2    Huffaker, T.B.3    Runtsch, M.C.4
  • 69
    • 84939654767 scopus 로고    scopus 로고
    • Regulation of the germinal center response by microRNA-155
    • Material SO, Web S, Web ISI, Press H, et al. 2008. Regulation of the germinal center response by microRNA-155. Science 604: 604-8.
    • (2008) Science , vol.604 , pp. 604-608
    • Material, S.O.1    Web, S.2    Web, I.S.I.3    Press, H.4
  • 70
    • 77958495102 scopus 로고    scopus 로고
    • MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
    • O'Connell RM, Kahn D, Gibson WSJ, Round JL, et al. 2010. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 33: 607-19.
    • (2010) Immunity , vol.33 , pp. 607-619
    • O'Connell, R.M.1    Kahn, D.2    Gibson, W.S.J.3    Round, J.L.4
  • 71
  • 72
    • 84890283575 scopus 로고    scopus 로고
    • MiR-125a-5p regulates differential activation of macrophages and inflammation
    • Banerjee S, Cui H, Xie N, Tan Z, et al. 2013. MiR-125a-5p regulates differential activation of macrophages and inflammation. J Biol Chem 288: 35428-36.
    • (2013) J Biol Chem , vol.288 , pp. 35428-35436
    • Banerjee, S.1    Cui, H.2    Xie, N.3    Tan, Z.4
  • 73
    • 84862150859 scopus 로고    scopus 로고
    • A novel regulator of macrophage activation: MiR-223 in obesity-associated adipose tissue inflammation
    • Zhuang G, Meng C, Guo X, Cheruku PS, et al. 2012. A novel regulator of macrophage activation: MiR-223 in obesity-associated adipose tissue inflammation. Circulation 125: 2892-903.
    • (2012) Circulation , vol.125 , pp. 2892-2903
    • Zhuang, G.1    Meng, C.2    Guo, X.3    Cheruku, P.S.4
  • 74
    • 39849096995 scopus 로고    scopus 로고
    • Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    • Johnnidis JB, Harris MH, Wheeler RT, Stehling-Sun S, et al. 2008. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 451: 1125-9.
    • (2008) Nature , vol.451 , pp. 1125-1129
    • Johnnidis, J.B.1    Harris, M.H.2    Wheeler, R.T.3    Stehling-Sun, S.4
  • 75
    • 84857420754 scopus 로고    scopus 로고
    • MicroRNAs and hematopoietic cell development
    • O'Connell RM, Baltimore D. 2012. MicroRNAs and hematopoietic cell development. Curr Top Dev Biol 99: 145-74.
    • (2012) Curr Top Dev Biol , vol.99 , pp. 145-174
    • O'Connell, R.M.1    Baltimore, D.2
  • 78
    • 84876746489 scopus 로고    scopus 로고
    • MicroRNA-155 is required for effector cd8+ t cell responses to virus infection and cancer
    • Dudda JC, Salaun B, Ji Y, Palmer DC, et al. 2013. MicroRNA-155 is required for effector cd8+ t cell responses to virus infection and cancer. Immunity 38: 742-53.
    • (2013) Immunity , vol.38 , pp. 742-753
    • Dudda, J.C.1    Salaun, B.2    Ji, Y.3    Palmer, D.C.4
  • 79
    • 84890284251 scopus 로고    scopus 로고
    • Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse
    • Thai T-H, Patterson HC, Pham D-H, Kis-Toth K, et al. 2013. Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse. Proc Natl Acad Sci USA 110: 20194-9.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 20194-20199
    • Thai, T.-H.1    Patterson, H.C.2    Pham, D.-H.3    Kis-Toth, K.4
  • 80
    • 84880778954 scopus 로고    scopus 로고
    • The microRNA cluster miR-17~92 promotes TFH cell differentiation and represses subset-inappropriate gene expression
    • Baumjohann D, Kageyama R, Clingan JM, Morar MM, et al. 2013. The microRNA cluster miR-17~92 promotes TFH cell differentiation and represses subset-inappropriate gene expression. Nat Immunol 14: 840-8.
    • (2013) Nat Immunol , vol.14 , pp. 840-848
    • Baumjohann, D.1    Kageyama, R.2    Clingan, J.M.3    Morar, M.M.4
  • 81
    • 81555196345 scopus 로고    scopus 로고
    • Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation
    • Jiang S, Li C, Olive V, Lykken E, et al. 2011. Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation. Blood 118: 5487-97.
    • (2011) Blood , vol.118 , pp. 5487-5497
    • Jiang, S.1    Li, C.2    Olive, V.3    Lykken, E.4
  • 82
    • 84911214633 scopus 로고    scopus 로고
    • A microRNA upregulated in asthma airway T cells promotes T H 2 cytokine production
    • Simpson LJ, Patel S, Bhakta NR, Choy DF, et al. 2014. A microRNA upregulated in asthma airway T cells promotes T H 2 cytokine production. Nat Immunol 15: 1162-70.
    • (2014) Nat Immunol , vol.15 , pp. 1162-1170
    • Simpson, L.J.1    Patel, S.2    Bhakta, N.R.3    Choy, D.F.4
  • 83
    • 84903484100 scopus 로고    scopus 로고
    • MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi
    • Lochhead RB, Ma Y, Zachary JF, Baltimore D, et al. 2014. MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. PLoS Pathog 10: e1004212.
    • (2014) PLoS Pathog , vol.10 , pp. e1004212
    • Lochhead, R.B.1    Ma, Y.2    Zachary, J.F.3    Baltimore, D.4
  • 84
    • 29344467120 scopus 로고    scopus 로고
    • A developmental timing microRNA and its target regulate life span in C. elegans
    • Boehm M, Slack F. 2005. A developmental timing microRNA and its target regulate life span in C. elegans. Science 310: 1954-7.
    • (2005) Science , vol.310 , pp. 1954-1957
    • Boehm, M.1    Slack, F.2
  • 85
    • 84873298811 scopus 로고    scopus 로고
    • MicroRNAs in age-related diseases
    • Dimmeler S, Nicotera P. 2013. MicroRNAs in age-related diseases. EMBO Mol Med 5: 180-90.
    • (2013) EMBO Mol Med , vol.5 , pp. 180-190
    • Dimmeler, S.1    Nicotera, P.2
  • 86
    • 79959362128 scopus 로고    scopus 로고
    • NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
    • Zhao JL, Rao DS, Boldin MP, Taganov KD, et al. 2011. NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc Natl Acad Sci USA 108: 9184-9.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 9184-9189
    • Zhao, J.L.1    Rao, D.S.2    Boldin, M.P.3    Taganov, K.D.4
  • 87
    • 84917679127 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of intestinal homeostasis
    • Runtsch MC, Round JL, O'Connell RM. 2014. MicroRNAs and the regulation of intestinal homeostasis. Front Genet 5: 1-10.
    • (2014) Front Genet , vol.5 , pp. 1-10
    • Runtsch, M.C.1    Round, J.L.2    O'Connell, R.M.3
  • 88
    • 84874714511 scopus 로고    scopus 로고
    • Enhanced susceptibility to citrobacter rodentium infection in microRNA-155-Deficient mice
    • Clare S, John V, Walker AW, Hill JL, et al. 2013. Enhanced susceptibility to citrobacter rodentium infection in microRNA-155-Deficient mice. Infect Immun 81: 723-32.
    • (2013) Infect Immun , vol.81 , pp. 723-732
    • Clare, S.1    John, V.2    Walker, A.W.3    Hill, J.L.4
  • 89
    • 79953726990 scopus 로고    scopus 로고
    • Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes
    • Balasubramanyam M, Aravind S, Gokulakrishnan K, Prabu P, et al. 2011. Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes. Mol Cell Biochem 351: 197-205.
    • (2011) Mol Cell Biochem , vol.351 , pp. 197-205
    • Balasubramanyam, M.1    Aravind, S.2    Gokulakrishnan, K.3    Prabu, P.4
  • 90
    • 74949113627 scopus 로고    scopus 로고
    • Diagnostic microRNA markers for screening sporadic human colon cancer and active ulcerative colitis in stool and tissue
    • Ahmed FE, Jeffries CD, Vos PW, Flake G, et al. 2009. Diagnostic microRNA markers for screening sporadic human colon cancer and active ulcerative colitis in stool and tissue. Cancer Genomics Proteomics 296: 281-95.
    • (2009) Cancer Genomics Proteomics , vol.296 , pp. 281-295
    • Ahmed, F.E.1    Jeffries, C.D.2    Vos, P.W.3    Flake, G.4
  • 91
    • 82255186392 scopus 로고    scopus 로고
    • Micro-RNAs as regulators and possible diagnostic bio-markers in inflammatory bowel disease
    • Archanioti P, Gazouli M, Theodoropoulos G, Vaiopoulou A, et al. 2011. Micro-RNAs as regulators and possible diagnostic bio-markers in inflammatory bowel disease. J Crohn's Colitis 5: 520-4.
    • (2011) J Crohn's Colitis , vol.5 , pp. 520-524
    • Archanioti, P.1    Gazouli, M.2    Theodoropoulos, G.3    Vaiopoulou, A.4
  • 92
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E, Seike M, et al. 2006. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9: 189-98.
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3    Seike, M.4
  • 94
    • 84880008053 scopus 로고    scopus 로고
    • Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease
    • Iborra M, Bernuzzi F, Correale C, Vetrano S, et al. 2013. Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease. Clin Exp Immunol 173: 250-8.
    • (2013) Clin Exp Immunol , vol.173 , pp. 250-258
    • Iborra, M.1    Bernuzzi, F.2    Correale, C.3    Vetrano, S.4
  • 95
    • 84860218631 scopus 로고    scopus 로고
    • Intercellular communication: diverse structures for exchange of genetic information
    • Mittelbrunn M, Sánchez-Madrid F. 2012. Intercellular communication: diverse structures for exchange of genetic information. Nat Rev Mol Cell Biol 5: 328-35.
    • (2012) Nat Rev Mol Cell Biol , vol.5 , pp. 328-335
    • Mittelbrunn, M.1    Sánchez-Madrid, F.2
  • 96
    • 84896818399 scopus 로고    scopus 로고
    • Regulation of immune responses by extracellular vesicles
    • Robbins PD, Morelli AE. 2014. Regulation of immune responses by extracellular vesicles. Nat Rev Immunol 14: 195-208.
    • (2014) Nat Rev Immunol , vol.14 , pp. 195-208
    • Robbins, P.D.1    Morelli, A.E.2
  • 97
    • 84904396495 scopus 로고    scopus 로고
    • MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells
    • Okoye IS, Coomes SM, Pelly VS, Czieso S, et al. 2014. MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells. Immunity 41: 89-103.
    • (2014) Immunity , vol.41 , pp. 89-103
    • Okoye, I.S.1    Coomes, S.M.2    Pelly, V.S.3    Czieso, S.4
  • 98
    • 84862908547 scopus 로고    scopus 로고
    • Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
    • Montecalvo A, Larregina AT, Shufesky WJ, Stolz DB, et al. 2012. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 119: 756-66.
    • (2012) Blood , vol.119 , pp. 756-766
    • Montecalvo, A.1    Larregina, A.T.2    Shufesky, W.J.3    Stolz, D.B.4
  • 99
    • 84934903985 scopus 로고    scopus 로고
    • Exosome-delivered microRNAs modulate the inflammatory response to endotoxin
    • Alexander M, Hu R, Runtsch MC, Kagele DA, et al. 2015. Exosome-delivered microRNAs modulate the inflammatory response to endotoxin. Nature Comm 6: 7321.
    • (2015) Nature Comm , vol.6 , pp. 7321
    • Alexander, M.1    Hu, R.2    Runtsch, M.C.3    Kagele, D.A.4
  • 100
    • 84905503012 scopus 로고    scopus 로고
    • Therapeutic targeting of microRNAs: current status and future challenges
    • Li Z, Rana TM. 2014. Therapeutic targeting of microRNAs: current status and future challenges. Nat Rev Drug Discov 13: 622-38.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 622-638
    • Li, Z.1    Rana, T.M.2
  • 102
    • 84871923602 scopus 로고    scopus 로고
    • Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells
    • Ohno S, Takanashi M, Sudo K, Ueda S, et al. 2013. Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells. Mol Ther 21: 185-91.
    • (2013) Mol Ther , vol.21 , pp. 185-191
    • Ohno, S.1    Takanashi, M.2    Sudo, K.3    Ueda, S.4
  • 103
    • 84911889779 scopus 로고    scopus 로고
    • Regulation of inflammatory phenotype in macrophages by a diabetes-induced long non-coding RNA
    • Reddy M, Chen Z, Park JT, Wang M, et al. 2014. Regulation of inflammatory phenotype in macrophages by a diabetes-induced long non-coding RNA. Diabetes 63: 4249-61.
    • (2014) Diabetes , vol.63 , pp. 4249-4261
    • Reddy, M.1    Chen, Z.2    Park, J.T.3    Wang, M.4
  • 104
    • 84881478367 scopus 로고    scopus 로고
    • A long noncoding RNA mediates both activation and repression of immune response genes
    • Carpenter S, Aiello D, Atianand MK, Ricci EP, et al. 2014. A long noncoding RNA mediates both activation and repression of immune response genes. Science 341: 789-92.
    • (2014) Science , vol.341 , pp. 789-792
    • Carpenter, S.1    Aiello, D.2    Atianand, M.K.3    Ricci, E.P.4
  • 105
    • 67649160600 scopus 로고    scopus 로고
    • Genome-wide identification of long noncoding RNAs in CD8+ T cells
    • Pang KC, Dinger ME, Mercer TR, Malquori L, et al. 2009. Genome-wide identification of long noncoding RNAs in CD8+ T cells. J Immunol 182: 7738-48.
    • (2009) J Immunol , vol.182 , pp. 7738-7748
    • Pang, K.C.1    Dinger, M.E.2    Mercer, T.R.3    Malquori, L.4
  • 107
    • 41149130219 scopus 로고    scopus 로고
    • Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
    • O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, et al. 2008. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 205: 585-94.
    • (2008) J Exp Med , vol.205 , pp. 585-594
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Boldin, M.P.4
  • 108
    • 84871694595 scopus 로고    scopus 로고
    • Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity
    • Huffaker TB, Hu R, Runtsch MC, Bake E, et al. 2012. Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity. Cell Rep 2: 1697-709.
    • (2012) Cell Rep , vol.2 , pp. 1697-1709
    • Huffaker, T.B.1    Hu, R.2    Runtsch, M.C.3    Bake, E.4
  • 109
    • 79958257077 scopus 로고    scopus 로고
    • miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
    • Boldin MP, Taganov KD, Rao DS, Yang L, et al. 2011. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med 208: 1189-201.
    • (2011) J Exp Med , vol.208 , pp. 1189-1201
    • Boldin, M.P.1    Taganov, K.D.2    Rao, D.S.3    Yang, L.4
  • 110
    • 39749163245 scopus 로고    scopus 로고
    • Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
    • Xiao C, Srinivasan L, Calado DP, Patterson HC, et al. 2008. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 9: 405-14.
    • (2008) Nat Immunol , vol.9 , pp. 405-414
    • Xiao, C.1    Srinivasan, L.2    Calado, D.P.3    Patterson, H.C.4
  • 111
    • 84887605316 scopus 로고    scopus 로고
    • The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
    • Mogilyansky E, Rigoutsos I. 2013. The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease. Cell Death Differ 20: 1603-14.
    • (2013) Cell Death Differ , vol.20 , pp. 1603-1614
    • Mogilyansky, E.1    Rigoutsos, I.2
  • 112
    • 84870293512 scopus 로고    scopus 로고
    • Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
    • Li G, Yu M, Lee W-W, Tsang M, et al. 2012. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 18: 1518-24.
    • (2012) Nat Med , vol.18 , pp. 1518-1524
    • Li, G.1    Yu, M.2    Lee, W.-W.3    Tsang, M.4
  • 113
    • 77958149675 scopus 로고    scopus 로고
    • The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
    • Stittrich A- B, Haftmann C, Sgouroudis E, Kühl AA, et al. 2010. The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. Nat Immunol 11: 1057-62.
    • (2010) Nat Immunol , vol.11 , pp. 1057-1062
    • Stittrich, A.-B.1    Haftmann, C.2    Sgouroudis, E.3    Kühl, A.A.4
  • 114
    • 84864812650 scopus 로고    scopus 로고
    • miR-29ab1-deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis
    • Bottoni A, Cox GM, Satoskar AR, Croce CM, et al. 2012. miR-29ab1-deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis. J Immunol 189: 1567-76.
    • (2012) J Immunol , vol.189 , pp. 1567-1576
    • Bottoni, A.1    Cox, G.M.2    Satoskar, A.R.3    Croce, C.M.4
  • 115
    • 55249119513 scopus 로고    scopus 로고
    • MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2α
    • Wu F, Zikusoka M, Trindade A, Dassopoulos T, et al. 2008. MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2α. Gastroenterology 135: 1624-35.
    • (2008) Gastroenterology , vol.135 , pp. 1624-1635
    • Wu, F.1    Zikusoka, M.2    Trindade, A.3    Dassopoulos, T.4
  • 116
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway
    • Ponomarev ED, Veremeyko T, Barteneva N, Krichevsky AM, et al. 2011. MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway. Nat Med 17: 64-70.
    • (2011) Nat Med , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4
  • 117
    • 84881478367 scopus 로고    scopus 로고
    • A long noncoding RNA mediates both activation and repression of immune response genes
    • Carpenter S, Aiello D, Atianand MK, Ricci EP, et al. 2013. A long noncoding RNA mediates both activation and repression of immune response genes. Science 341: 789-92.
    • (2013) Science , vol.341 , pp. 789-792
    • Carpenter, S.1    Aiello, D.2    Atianand, M.K.3    Ricci, E.P.4
  • 118
    • 84874025014 scopus 로고    scopus 로고
    • The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus
    • Gomez JA, Wapinski OL, Yang YW, Bureau JF, et al. 2013. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell 152: 743-54.
    • (2013) Cell , vol.152 , pp. 743-754
    • Gomez, J.A.1    Wapinski, O.L.2    Yang, Y.W.3    Bureau, J.F.4
  • 119
    • 84899486799 scopus 로고    scopus 로고
    • The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation
    • Wang P, Xue Y, Han Y, Lin L, et al. 2014. The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science 344: 310-3.
    • (2014) Science , vol.344 , pp. 310-313
    • Wang, P.1    Xue, Y.2    Han, Y.3    Lin, L.4
  • 120
    • 84886724189 scopus 로고    scopus 로고
    • Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation
    • Hu G, Tang Q, Sharma S, Yu F, et al. 2013. Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation. Nat Immunol 14: 1190-8.
    • (2013) Nat Immunol , vol.14 , pp. 1190-1198
    • Hu, G.1    Tang, Q.2    Sharma, S.3    Yu, F.4
  • 121
    • 84892923750 scopus 로고    scopus 로고
    • The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL
    • Li Z, Chao T-C, Chang K-Y, Lin N, et al. 2014. The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proc Natl Acad Sci USA 111: 1002-7.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 1002-1007
    • Li, Z.1    Chao, T.-C.2    Chang, K.-Y.3    Lin, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.