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Volumn 5, Issue OCT, 2014, Pages

MicroRNAs and the regulation of intestinal homeostasis

Author keywords

Homeostasis; Host commensal; Immune system; Intestine; Microbiota; MicroRNAs

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MICRORNA; MICRORNA 10A; MICRORNA 122; MICRORNA 124; MICRORNA 143; MICRORNA 145; MICRORNA 146A; MICRORNA 155; MICRORNA 21; MICRORNA 29; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

EID: 84917679127     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00347     Document Type: Review
Times cited : (79)

References (77)
  • 1
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham, C., and Cho, J. H. (2009). Inflammatory bowel disease. N. Engl. J. Med. 361, 2066-2078.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 2
    • 75649093343 scopus 로고    scopus 로고
    • Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
    • Abreu, M. T. (2010). Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat. Rev. Immunol. 10, 131-144. doi: 10.1038/nri2707
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 131-144
    • Abreu, M.T.1
  • 3
    • 84891618594 scopus 로고    scopus 로고
    • The intestinal microbiota interferes with the microRNA response upon oral Listeria infection
    • Archambaud, C., Sismeiro, O., Toedling, J., Intestinal, T., Interferes, M., Response, R. N. A.,et al. (2013). The intestinal microbiota interferes with the microRNA response upon oral Listeria infection. MBio 4, e00707-e00713. doi: 10.1128/mBio.00707-13
    • (2013) MBio , vol.4 , pp. e00707-e00713
    • Archambaud, C.1    Sismeiro, O.2    Toedling, J.3    Intestinal, T.4    Interferes, M.5    Response, R.N.A.6
  • 4
    • 47849125676 scopus 로고    scopus 로고
    • MicroRNAs: new regulators of immune cell development and function
    • Baltimore, D., Boldin, M. P., O'Connell, R. M., Rao, D. S., and Taganov, K. D. (2008). MicroRNAs: new regulators of immune cell development and function. Nat. Immunol. 9, 839-845. doi: 10.1038/ni.f.209
    • (2008) Nat. Immunol. , vol.9 , pp. 839-845
    • Baltimore, D.1    Boldin, M.P.2    O'Connell, R.M.3    Rao, D.S.4    Taganov, K.D.5
  • 5
    • 79951598704 scopus 로고    scopus 로고
    • Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk
    • Biton, M., Levin, A., Slyper, M., Alkalay, I., Horwitz, E., Mor, H.,et al. (2011). Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nat. Immunol. 12, 239-246. doi: 10.1038/ni.1994
    • (2011) Nat. Immunol. , vol.12 , pp. 239-246
    • Biton, M.1    Levin, A.2    Slyper, M.3    Alkalay, I.4    Horwitz, E.5    Mor, H.6
  • 6
    • 79958257077 scopus 로고    scopus 로고
    • miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
    • Boldin, M. P., Taganov, K. D., Rao, D. S., Yang, L., Zhao, J. L., Kalwani, M.,et al. (2011). miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J. Exp. Med. 208, 1189-1201. doi: 10.1084/jem.20101823
    • (2011) J. Exp. Med. , vol.208 , pp. 1189-1201
    • Boldin, M.P.1    Taganov, K.D.2    Rao, D.S.3    Yang, L.4    Zhao, J.L.5    Kalwani, M.6
  • 7
    • 84884315797 scopus 로고    scopus 로고
    • The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release
    • Brain, O., Owens, B. M. J., Pichulik, T., Allan, P., Khatamzas, E., Leslie, A.,et al. (2013). The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. Immunity 39, 521-536. doi: 10.1016/j.immuni.2013.08.035
    • (2013) Immunity , vol.39 , pp. 521-536
    • Brain, O.1    Owens, B.M.J.2    Pichulik, T.3    Allan, P.4    Khatamzas, E.5    Leslie, A.6
  • 8
    • 84879369738 scopus 로고    scopus 로고
    • Commensal bacteria at the interface of host metabolism and the immune system
    • Brestoff, J. R., and Artis, D. (2013). Commensal bacteria at the interface of host metabolism and the immune system. Nat. Immunol. 14, 676-684. doi: 10.1038/ni.2640
    • (2013) Nat. Immunol. , vol.14 , pp. 676-684
    • Brestoff, J.R.1    Artis, D.2
  • 9
    • 84883278635 scopus 로고    scopus 로고
    • A miR-146a polymorphism (rs2910164) predicts risk of and survival from colorectal cancer
    • Chae, Y., Kim, J. G., Lee, S. L., Kang, B. W., Lee, Y. J., Park, J. Y.,et al. (2013). A miR-146a polymorphism (rs2910164) predicts risk of and survival from colorectal cancer. Anticancer Res. 33, 3233-3239.
    • (2013) Anticancer Res , vol.33 , pp. 3233-3239
    • Chae, Y.1    Kim, J.G.2    Lee, S.L.3    Kang, B.W.4    Lee, Y.J.5    Park, J.Y.6
  • 10
    • 84872411376 scopus 로고    scopus 로고
    • MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury
    • Chassin, C., Hempel, C., Stockinger, S., Dupont, A., Kübler, J. F., Wedemeyer, J.,et al. (2012). MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury. EMBO Mol. Med. 4, 1308-1319. doi: 10.1002/emmm.201201298
    • (2012) EMBO Mol. Med. , vol.4 , pp. 1308-1319
    • Chassin, C.1    Hempel, C.2    Stockinger, S.3    Dupont, A.4    Kübler, J.F.5    Wedemeyer, J.6
  • 11
    • 84875769575 scopus 로고    scopus 로고
    • Regulation of immune responses and tolerance: the microRNA perspective
    • Chen, C.-Z., Schaffert, S., Fragoso, R., and Loh, C. (2013). Regulation of immune responses and tolerance: the microRNA perspective. Immunol. Rev. 253, 112-128. doi: 10.1111/imr.12060
    • (2013) Immunol. Rev. , vol.253 , pp. 112-128
    • Chen, C.-Z.1    Schaffert, S.2    Fragoso, R.3    Loh, C.4
  • 12
    • 84901318452 scopus 로고    scopus 로고
    • An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration
    • Chivukula, R. R., Shi, G., Acharya, A., Mills, E. W., Zeitels, L. R., Anandam, J. L.,et al. (2014). An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell 157, 1104-1116. doi: 10.1016/j.cell.2014.03.055
    • (2014) Cell , vol.157 , pp. 1104-1116
    • Chivukula, R.R.1    Shi, G.2    Acharya, A.3    Mills, E.W.4    Zeitels, L.R.5    Anandam, J.L.6
  • 13
    • 84874714511 scopus 로고    scopus 로고
    • Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice Infect
    • Clare, S., John, V., Walker, A. W., Hill, J. L., Abreu-Goodger, C., Hale, C.,et al. (2013). Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice. Infect. Immun. 81, 723-732. doi: 10.1128/IAI.00969-12
    • (2013) Immun , vol.81 , pp. 723-732
    • Clare, S.1    John, V.2    Walker, A.W.3    Hill, J.L.4    Abreu-Goodger, C.5    Hale, C.6
  • 14
    • 84867845255 scopus 로고    scopus 로고
    • The interplay between the intestinal microbiota and the brain
    • Collins, S. M., Surette, M., and Bercik, P. (2012). The interplay between the intestinal microbiota and the brain. Nat. Rev. Microbiol. 10, 735-742. doi: 10.1038/nrmicro2876
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 735-742
    • Collins, S.M.1    Surette, M.2    Bercik, P.3
  • 15
    • 78650484049 scopus 로고    scopus 로고
    • The role of microRNA in inflammatory bowel disease
    • Dalal, S., and Kwon, J. (2010). The role of microRNA in inflammatory bowel disease. Gastroenterol. Hepatol. 6, 714-722.
    • (2010) Gastroenterol. Hepatol. , vol.6 , pp. 714-722
    • Dalal, S.1    Kwon, J.2
  • 17
    • 84874087148 scopus 로고    scopus 로고
    • TGF-β conditions intestinal T cells to express increased levels of miR-155, associated with down-regulation of IL-2 and itk mRNA
    • Das, L. M., Torres-Castillo, M. D. L. A., Gill, T., and Levine, A. D. (2013). TGF-β conditions intestinal T cells to express increased levels of miR-155, associated with down-regulation of IL-2 and itk mRNA. Mucosal Immunol. 6, 167-176. doi: 10.1038/mi.2012.60
    • (2013) Mucosal Immunol , vol.6 , pp. 167-176
    • Das, L.M.1    Torres-Castillo, M.D.L.A.2    Gill, T.3    Levine, A.D.4
  • 18
    • 70049099845 scopus 로고    scopus 로고
    • Immune responses to the microbiota at the intestinal mucosal surface
    • Duerkop, B. A., Vaishnava, S., and Hooper, L. V. (2009). Immune responses to the microbiota at the intestinal mucosal surface. Immunity 31, 368-376. doi: 10.1016/j.immuni.2009.08.009
    • (2009) Immunity , vol.31 , pp. 368-376
    • Duerkop, B.A.1    Vaishnava, S.2    Hooper, L.V.3
  • 19
    • 84875367117 scopus 로고    scopus 로고
    • Gut bacteria-host metabolic interplay during conventionalisation of the mouse germfree colon
    • El Aidy, S., Derrien, M., Merrifield, C. A., Levenez, F., Doré, J., Boekschoten, M. V.,et al. (2013). Gut bacteria-host metabolic interplay during conventionalisation of the mouse germfree colon. ISME J. 7, 743-755. doi: 10.1038/ismej.2012.142
    • (2013) ISME J , vol.7 , pp. 743-755
    • El Aidy, S.1    Derrien, M.2    Merrifield, C.A.3    Levenez, F.4    Doré, J.5    Boekschoten, M.V.6
  • 20
    • 84864886608 scopus 로고    scopus 로고
    • Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides
    • Frantz, A. L., Rogier, E. W., Weber, C. R., Shen, L., Cohen, D. A., Fenton, L. A.,et al. (2012). Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides. Mucosal Immunol. 5, 501-512. doi: 10.1038/mi.2012.23
    • (2012) Mucosal Immunol , vol.5 , pp. 501-512
    • Frantz, A.L.1    Rogier, E.W.2    Weber, C.R.3    Shen, L.4    Cohen, D.A.5    Fenton, L.A.6
  • 21
    • 84881480713 scopus 로고    scopus 로고
    • Association study of genetic variants in miRNAs in patients with inflammatory bowel disease: preliminary results
    • Gazouli, M., Papaconstantinou, I., Stamatis, K., Vaiopoulou, A., Zeglinas, C., Vassiliou, I.,et al. (2013). Association study of genetic variants in miRNAs in patients with inflammatory bowel disease: preliminary results. Dig. Dis. Sci. 58, 2324-2328. doi: 10.1007/s10620-013-2640-y
    • (2013) Dig. Dis. Sci. , vol.58 , pp. 2324-2328
    • Gazouli, M.1    Papaconstantinou, I.2    Stamatis, K.3    Vaiopoulou, A.4    Zeglinas, C.5    Vassiliou, I.6
  • 22
    • 84875222668 scopus 로고    scopus 로고
    • Intestinal epithelial cells as mediators of the commensal-host immune crosstalk
    • Goto, Y., and Ivanov, I. (2013). Intestinal epithelial cells as mediators of the commensal-host immune crosstalk. Immunol. Cell Biol. 91, 204-214. doi: 10.1038/icb.2012.80
    • (2013) Immunol. Cell Biol. , vol.91 , pp. 204-214
    • Goto, Y.1    Ivanov, I.2
  • 23
    • 84869104262 scopus 로고    scopus 로고
    • The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: evidence from published studies
    • He, B., Pan, Y., Cho, W. C., Xu, Y., Gu, L., Nie, Z.,et al. (2012). The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: evidence from published studies. PLoS ONE 7:e49032. doi: 10.1371/journal.pone.0049032
    • (2012) PLoS ONE , vol.7
    • He, B.1    Pan, Y.2    Cho, W.C.3    Xu, Y.4    Gu, L.5    Nie, Z.6
  • 24
    • 84861980130 scopus 로고    scopus 로고
    • Interactions between the microbiota and the immune system
    • Hooper, L. V., Littman, D. R., and Macpherson, A. J. (2012). Interactions between the microbiota and the immune system. Science 336, 1268-1273. doi: 10.1126/science.1223490
    • (2012) Science , vol.336 , pp. 1268-1273
    • Hooper, L.V.1    Littman, D.R.2    Macpherson, A.J.3
  • 25
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • Hooper, L. V., and Macpherson, A. J. (2010). Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat. Rev. Immunol. 10, 159-169. doi: 10.1038/nri2710
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 159-169
    • Hooper, L.V.1    Macpherson, A.J.2
  • 26
    • 84894118144 scopus 로고    scopus 로고
    • Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders
    • Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T.,et al. (2013). Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 155, 1451-1463. doi: 10.1016/j.cell.2013.11.024
    • (2013) Cell , vol.155 , pp. 1451-1463
    • Hsiao, E.Y.1    McBride, S.W.2    Hsien, S.3    Sharon, G.4    Hyde, E.R.5    McCue, T.6
  • 27
    • 79251644886 scopus 로고    scopus 로고
    • The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer
    • Hu, S., Dong, T. S., Dalal, S. R., Wu, F., Bissonnette, M., Kwon, J. H.,et al. (2011). The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer. PLoS ONE 6:e16221. doi: 10.1371/journal.pone.0016221
    • (2011) PLoS ONE , vol.6
    • Hu, S.1    Dong, T.S.2    Dalal, S.R.3    Wu, F.4    Bissonnette, M.5    Kwon, J.H.6
  • 28
    • 84880008053 scopus 로고    scopus 로고
    • Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease
    • Iborra, M., Bernuzzi, F., Correale, C., Vetrano, S., Fiorino, G., Beltrán, B.,et al. (2013). Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease. Clin. Exp. Immunol. 173, 250-258. doi: 10.1111/cei.12104
    • (2013) Clin. Exp. Immunol. , vol.173 , pp. 250-258
    • Iborra, M.1    Bernuzzi, F.2    Correale, C.3    Vetrano, S.4    Fiorino, G.5    Beltrán, B.6
  • 29
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U.,et al. (2009). Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139, 485-498. doi: 10.1016/j.cell.2009.09.033
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3    Brodie, E.L.4    Shima, T.5    Karaoz, U.6
  • 30
    • 84867658789 scopus 로고    scopus 로고
    • Intestinal commensal microbes as immune modulators
    • Ivanov, I. I., and Honda, K. (2012). Intestinal commensal microbes as immune modulators. Cell Host Microbe 12, 496-508. doi: 10.1016/j.chom.2012.09.009
    • (2012) Cell Host Microbe , vol.12 , pp. 496-508
    • Ivanov, I.I.1    Honda, K.2
  • 32
    • 85016354088 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms associated with microRNA regulation
    • Jin, Y., and Lee, C. (2013). Single nucleotide polymorphisms associated with microRNA regulation. Biomolecules 3, 287-302. doi: 10.3390/biom3020287
    • (2013) Biomolecules , vol.3 , pp. 287-302
    • Jin, Y.1    Lee, C.2
  • 33
    • 79952748335 scopus 로고    scopus 로고
    • The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
    • Johansson, M. E. V., Larsson, J. M. H., and Hansson, G. C. (2011). The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc. Natl. Acad. Sci. U.S.A. 108(Suppl. 1), 4659-4665. doi: 10.1073/pnas.1006451107
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 4659-4665
    • Johansson, M.E.V.1    Larsson, J.M.H.2    Hansson, G.C.3
  • 34
    • 84876913132 scopus 로고    scopus 로고
    • Role of the gut microbiota in immunity and inflammatory disease
    • Kamada, N., Seo, S.-U., Chen, G. Y., and Núñez, G. (2013). Role of the gut microbiota in immunity and inflammatory disease. Nat. Rev. Immunol. 13, 321-335. doi: 10.1038/nri3430
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 321-335
    • Kamada, N.1    Seo, S.-U.2    Chen, G.Y.3    Núñez, G.4
  • 35
    • 84884373262 scopus 로고    scopus 로고
    • MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis
    • Koukos, G., Polytarchou, C., Kaplan, J. L., Morley-Fletcher, A., Gras-Miralles, B., Kokkotou, E.,et al. (2013). MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis. Gastroenterology 145, 842-852.e2. doi: 10.1053/j.gastro.2013.07.001
    • (2013) Gastroenterology , vol.145 , pp. 842-852.e2
    • Koukos, G.1    Polytarchou, C.2    Kaplan, J.L.3    Morley-Fletcher, A.4    Gras-Miralles, B.5    Kokkotou, E.6
  • 36
    • 84897546925 scopus 로고    scopus 로고
    • Novel specific microRNA biomarkers in idiopathic inflammatory bowel disease unrelated to disease activity
    • Lin, J., Welker, N. C., Zhao, Z., Li, Y., Zhang, J., Reuss, S. A.,et al. (2014). Novel specific microRNA biomarkers in idiopathic inflammatory bowel disease unrelated to disease activity. Mod. Pathol. 27, 602-608. doi: 10.1038/modpathol.2013.152
    • (2014) Mod. Pathol. , vol.27 , pp. 602-608
    • Lin, J.1    Welker, N.C.2    Zhao, Z.3    Li, Y.4    Zhang, J.5    Reuss, S.A.6
  • 37
    • 45549103746 scopus 로고    scopus 로고
    • microRNAs and the immune response
    • Lindsay, M. A. (2008). microRNAs and the immune response. Trends Immunol. 29, 343-351. doi: 10.1016/j.it.2008.04.004
    • (2008) Trends Immunol , vol.29 , pp. 343-351
    • Lindsay, M.A.1
  • 38
    • 77954162817 scopus 로고    scopus 로고
    • The role of microRNAs in colorectal cancer
    • Liu, M., and Chen, H. (2010). The role of microRNAs in colorectal cancer. J. Genet. Genomics 37, 347-358. doi: 10.1016/S1673-8527(09)60053-9
    • (2010) J. Genet. Genomics , vol.37 , pp. 347-358
    • Liu, M.1    Chen, H.2
  • 39
    • 74249095917 scopus 로고    scopus 로고
    • miR-10 in development and cancer
    • Lund, A. H. (2010). miR-10 in development and cancer. Cell Death. Differ. 17, 209-214. doi: 10.1038/cdd.2009.58
    • (2010) Cell Death. Differ. , vol.17 , pp. 209-214
    • Lund, A.H.1
  • 40
    • 80052033649 scopus 로고    scopus 로고
    • The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ
    • Ma, F., Xu, S., Liu, X., Zhang, Q., Xu, X., Liu, M.,et al. (2011). The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ. Nat. Immunol. 12, 861-869. doi: 10.1038/ni.2073
    • (2011) Nat. Immunol. , vol.12 , pp. 861-869
    • Ma, F.1    Xu, S.2    Liu, X.3    Zhang, Q.4    Xu, X.5    Liu, M.6
  • 41
    • 84886912635 scopus 로고    scopus 로고
    • A genetic variant in miR-146a modifies colorectal cancer susceptibility in a Chinese population
    • Ma, L., Zhu, L., Gu, D., Chu, H., Tong, N., Chen, J.,et al. (2013). A genetic variant in miR-146a modifies colorectal cancer susceptibility in a Chinese population. Arch. Toxicol. 87, 823-833. doi: 10.1007/s00204-012-1004-2
    • (2013) Arch. Toxicol. , vol.87 , pp. 823-833
    • Ma, L.1    Zhu, L.2    Gu, D.3    Chu, H.4    Tong, N.5    Chen, J.6
  • 42
    • 84885896439 scopus 로고    scopus 로고
    • LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7
    • Madison, B. B., Liu, Q., Zhong, X., Hahn, C. M., Lin, N., Emmett, M. J.,et al. (2013). LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. Genes Dev. 27, 2233-2245. doi: 10.1101/gad.224659.113
    • (2013) Genes Dev , vol.27 , pp. 2233-2245
    • Madison, B.B.1    Liu, Q.2    Zhong, X.3    Hahn, C.M.4    Lin, N.5    Emmett, M.J.6
  • 43
    • 78049468823 scopus 로고    scopus 로고
    • MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function
    • McKenna, L. B., Schug, J., Vourekas, A., McKenna, J. B., Bramswig, N. C., Friedman, J. R.,et al. (2010). MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology 139, 1654-1664. doi: 10.1053/j.gastro.2010.07.040
    • (2010) Gastroenterology , vol.139 , pp. 1654-1664
    • McKenna, L.B.1    Schug, J.2    Vourekas, A.3    McKenna, J.B.4    Bramswig, N.C.5    Friedman, J.R.6
  • 44
    • 84899639879 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • Neurath, M. F. (2014). Cytokines in inflammatory bowel disease. Nat. Rev. Immunol. 14, 329-342. doi: 10.1038/nri3661
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 329-342
    • Neurath, M.F.1
  • 45
    • 84859382730 scopus 로고    scopus 로고
    • microRNA regulation of inflammatory responses
    • O'Connell, R. M., Rao, D. S., and Baltimore, D. (2012). microRNA regulation of inflammatory responses. Annu. Rev. Immunol. 30, 295-312. doi: 10.1146/annurev-immunol-020711-075013
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 295-312
    • O'Connell, R.M.1    Rao, D.S.2    Baltimore, D.3
  • 46
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell, R. M., Rao, D. S., Chaudhuri, A. A., and Baltimore, D. (2010). Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 10, 111-122. doi: 10.1038/nri2708
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 47
    • 79953869884 scopus 로고    scopus 로고
    • Association study of common genetic variants in pre-microRNAs in patients with ulcerative colitis
    • Okubo, M., Tahara, T., Shibata, T., Yamashita, H., Nakamura, M., Yoshioka, D.,et al. (2011). Association study of common genetic variants in pre-microRNAs in patients with ulcerative colitis. J. Clin. Immunol. 31, 69-73. doi: 10.1007/s10875-010-9461-y
    • (2011) J. Clin. Immunol. , vol.31 , pp. 69-73
    • Okubo, M.1    Tahara, T.2    Shibata, T.3    Yamashita, H.4    Nakamura, M.5    Yoshioka, D.6
  • 48
    • 83555161689 scopus 로고    scopus 로고
    • MicroRNAs in inflammatory bowel disease
    • Pekow, J. R., and Kwon, J. H. (2012). MicroRNAs in inflammatory bowel disease. Inflamm. Bowel Dis. 18, 187-193. doi: 10.1002/ibd.21691
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 187-193
    • Pekow, J.R.1    Kwon, J.H.2
  • 49
    • 84896851032 scopus 로고    scopus 로고
    • Intestinal epithelial cells: regulators of barrier function and immune homeostasis
    • Peterson, L. W., and Artis, D. (2014). Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat. Rev. Immunol. 14, 141-153. doi: 10.1038/nri3608
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 141-153
    • Peterson, L.W.1    Artis, D.2
  • 50
    • 66349127355 scopus 로고    scopus 로고
    • Gut reaction: environmental effects on the human microbiota
    • Phillips, M. L. (2009). Gut reaction: environmental effects on the human microbiota. Environ. Health Perspect. 117, A198-A205. doi: 10.1289/ehp.117-a198
    • (2009) Environ. Health Perspect. , vol.117 , pp. A198-A205
    • Phillips, M.L.1
  • 51
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., and Medzhitov, R. (2004). Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118, 229-241. doi: 10.1016/j.cell.2004.07.002
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 52
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round, J. L., Lee, S. M., Li, J., Tran, G., Jabri, B., Chatila, T. A.,et al. (2011). The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 332, 974-977. doi: 10.1126/science.1206095
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3    Tran, G.4    Jabri, B.5    Chatila, T.A.6
  • 53
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round, J. L., and Mazmanian, S. K. (2009). The gut microbiota shapes intestinal immune responses during health and disease. Nat. Rev. Immunol. 9, 313-323. doi: 10.1038/nri2515
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 54
    • 84879174920 scopus 로고    scopus 로고
    • Deep sequencing the microRNA transcriptome in colorectal cancer
    • Schee, K., Lorenz, S., Worren, M. M., Günther, C.-C., Holden, M., Hovig, E.,et al. (2013). Deep sequencing the microRNA transcriptome in colorectal cancer. PLoS ONE 8:e66165. doi: 10.1371/journal.pone.0066165
    • (2013) PLoS ONE , vol.8
    • Schee, K.1    Lorenz, S.2    Worren, M.M.3    Günther, C.-C.4    Holden, M.5    Hovig, E.6
  • 55
    • 84896078883 scopus 로고    scopus 로고
    • Microbes, microbiota, and colon cancer
    • Sears, C. L., and Garrett, W. S. (2014). Microbes, microbiota, and colon cancer. Cell Host Microbe 15, 317-328. doi: 10.1016/j.chom.2014.02.007
    • (2014) Cell Host Microbe , vol.15 , pp. 317-328
    • Sears, C.L.1    Garrett, W.S.2
  • 56
    • 84896263746 scopus 로고    scopus 로고
    • The functional polymorphisms of miR-146a are associated with susceptibility to severe sepsis in the Chinese population
    • Shao, Y., Li, J., Cai, Y., Xie, Y., Ma, G., Li, Y.,et al. (2014). The functional polymorphisms of miR-146a are associated with susceptibility to severe sepsis in the Chinese population. Mediat. Inflamm. 2014, 916202. doi: 10.1155/2014/916202
    • (2014) Mediat. Inflamm. , vol.2014
    • Shao, Y.1    Li, J.2    Cai, Y.3    Xie, Y.4    Ma, G.5    Li, Y.6
  • 57
    • 84879476666 scopus 로고    scopus 로고
    • MicroRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury
    • Shi, C., Liang, Y., Yang, J., Xia, Y., Chen, H., Han, H.,et al. (2013). MicroRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury. PLoS ONE 8:e66814. doi: 10.1371/journal.pone.0066814
    • (2013) PLoS ONE , vol.8
    • Shi, C.1    Liang, Y.2    Yang, J.3    Xia, Y.4    Chen, H.5    Han, H.6
  • 58
    • 84856193897 scopus 로고    scopus 로고
    • The murine caecal microRNA signature depends on the presence of the endogenous microbiota
    • Singh, N., Shirdel, E. A., Waldron, L., Zhang, R.-H., Jurisica, I., and Comelli, E. M. (2012). The murine caecal microRNA signature depends on the presence of the endogenous microbiota. Int. J. Biol. Sci. 8, 171-186. doi: 10.7150/ijbs.8.171
    • (2012) Int. J. Biol. Sci. , vol.8 , pp. 171-186
    • Singh, N.1    Shirdel, E.A.2    Waldron, L.3    Zhang, R.-H.4    Jurisica, I.5    Comelli, E.M.6
  • 59
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
    • Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M.,et al. (2013). The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 341, 569-573. doi: 10.1126/science.1241165
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1    Howitt, M.R.2    Panikov, N.3    Michaud, M.4    Gallini, C.A.5    Bohlooly-Y, M.6
  • 60
    • 84876213407 scopus 로고    scopus 로고
    • Genetic polymorphisms of miR-146a and miR-27a, H. pylori infection, and risk of gastric lesions in a Chinese population
    • Song, M., Su, H., Zhang, L., Ma, J., Li, J., Pan, K.,et al. (2013). Genetic polymorphisms of miR-146a and miR-27a, H. pylori infection, and risk of gastric lesions in a Chinese population. PLoS ONE 8:e61250. doi: 10.1371/journal.pone.0061250
    • (2013) PLoS ONE , vol.8
    • Song, M.1    Su, H.2    Zhang, L.3    Ma, J.4    Li, J.5    Pan, K.6
  • 61
    • 84856077973 scopus 로고    scopus 로고
    • Functional transfer of microRNA by exosomes
    • Stoorvogel, W. (2012). Functional transfer of microRNA by exosomes. Blood 119, 646-648. doi: 10.1182/blood-2011-11-389478
    • (2012) Blood , vol.119 , pp. 646-648
    • Stoorvogel, W.1
  • 62
    • 84861230795 scopus 로고    scopus 로고
    • TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells
    • Takahashi, H., Kanno, T., Nakayamada, S., Hirahara, K., Sciumè, G., Muljo, S. A.,et al. (2012). TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells. Nat. Immunol. 13, 587-595. doi: 10.1038/ni.2286
    • (2012) Nat. Immunol. , vol.13 , pp. 587-595
    • Takahashi, H.1    Kanno, T.2    Nakayamada, S.3    Hirahara, K.4    Sciumè, G.5    Muljo, S.A.6
  • 63
    • 34247594818 scopus 로고    scopus 로고
    • Regulation of the germinal center response by microRNA-155
    • Thai, T.-H., Calado, D. P., Casola, S., Ansel, K. M., Xiao, C., Xue, Y.,et al. (2007). Regulation of the germinal center response by microRNA-155. Science 316, 604-608. doi: 10.1126/science.1141229
    • (2007) Science , vol.316 , pp. 604-608
    • Thai, T.-H.1    Calado, D.P.2    Casola, S.3    Ansel, K.M.4    Xiao, C.5    Xue, Y.6
  • 64
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • Vaishnava, S., Behrendt, C. L., Ismail, A. S., Eckmann, L., and Hooper, L. V. (2008). Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc. Natl. Acad. Sci. U.S.A. 105, 20858-20863. doi: 10.1073/pnas.0808723105
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 20858-20863
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3    Eckmann, L.4    Hooper, L.V.5
  • 65
    • 80054122238 scopus 로고    scopus 로고
    • The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
    • Vaishnava, S., Yamamoto, M., Severson, K. M., Ruhn, K. A., Yu, X., Koren, O.,et al. (2011). The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science 334, 255-258. doi: 10.1126/science.1209791
    • (2011) Science , vol.334 , pp. 255-258
    • Vaishnava, S.1    Yamamoto, M.2    Severson, K.M.3    Ruhn, K.A.4    Yu, X.5    Koren, O.6
  • 66
    • 37049002638 scopus 로고    scopus 로고
    • microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells
    • Vigorito, E., Perks, K. L., Abreu-Goodger, C., Bunting, S., Xiang, Z., Kohlhaas, S.,et al. (2007). microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 27, 847-859. doi: 10.1016/j.immuni.2007.10.009
    • (2007) Immunity , vol.27 , pp. 847-859
    • Vigorito, E.1    Perks, K.L.2    Abreu-Goodger, C.3    Bunting, S.4    Xiang, Z.5    Kohlhaas, S.6
  • 67
    • 77049099101 scopus 로고    scopus 로고
    • Lin28: a microRNA regulator with a macro role
    • Viswanathan, S. R., and Daley, G. Q. (2010). Lin28: a microRNA regulator with a macro role. Cell 140, 445-449. doi: 10.1016/j.cell.2010.02.007
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 68
    • 79953733693 scopus 로고    scopus 로고
    • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    • Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., Dugar, B.,et al. (2011). Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 472, 57-63. doi: 10.1038/nature09922
    • (2011) Nature , vol.472 , pp. 57-63
    • Wang, Z.1    Klipfell, E.2    Bennett, B.J.3    Koeth, R.4    Levison, B.S.5    Dugar, B.6
  • 69
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: microRNA biogenesis pathways and their regulation
    • Winter, J., Jung, S., Keller, S., Gregory, R. I., and Diederichs, S. (2009). Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat. Cell Biol. 11, 228-234. doi: 10.1038/ncb0309-228
    • (2009) Nat. Cell Biol. , vol.11 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederichs, S.5
  • 70
    • 78650119948 scopus 로고    scopus 로고
    • Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease
    • Wu, F., Guo, N., and Tian, H. (2011). Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease. Inflamm. Bowel Dis. 17, 241-250. doi: 10.1002/ibd.21450.Peripheral
    • (2011) Inflamm. Bowel Dis. , vol.17 , pp. 241-250
    • Wu, F.1    Guo, N.2    Tian, H.3
  • 71
    • 78649231641 scopus 로고    scopus 로고
    • Identification of microRNAs associated with ileal and colonic Crohn's disease
    • Wu, F., Zhang, S., Dassopoulos, T., Harris, M. L., Bayless, T. M., Meltzer, S. J.,et al. (2010). Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflamm. Bowel Dis. 16, 1729-1738. doi: 10.1002/ibd.21267.Identification
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 1729-1738
    • Wu, F.1    Zhang, S.2    Dassopoulos, T.3    Harris, M.L.4    Bayless, T.M.5    Meltzer, S.J.6
  • 72
    • 84896051012 scopus 로고    scopus 로고
    • Downregulation of microRNA-107 in intestinal CD11c(+) myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression
    • Xue, X., Cao, A. T., Cao, X., Yao, S., Carlsen, E. D., Soong, L.,et al. (2014). Downregulation of microRNA-107 in intestinal CD11c(+) myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression. Eur. J. Immunol. 44, 673-682. doi: 10.1002/eji.201343717
    • (2014) Eur. J. Immunol. , vol.44 , pp. 673-682
    • Xue, X.1    Cao, A.T.2    Cao, X.3    Yao, S.4    Carlsen, E.D.5    Soong, L.6
  • 73
    • 82755162151 scopus 로고    scopus 로고
    • Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40
    • Xue, X., Feng, T., Yao, S., Wolf, K. J., Liu, C.-G., Liu, X.,et al. (2011). Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40. J. Immunol. 187, 5879-5886. doi: 10.4049/jimmunol.1100535
    • (2011) J. Immunol. , vol.187 , pp. 5879-5886
    • Xue, X.1    Feng, T.2    Yao, S.3    Wolf, K.J.4    Liu, C.-G.5    Liu, X.6
  • 74
    • 80053581738 scopus 로고    scopus 로고
    • MicroRNA regulation of intestinal epithelial tight junction permeability
    • Ye, D., Guo, S., Al-Sadi, R., and Ma, T. Y. (2011). MicroRNA regulation of intestinal epithelial tight junction permeability. Gastroenterology 141, 1323-1333. doi: 10.1053/j.gastro.2011.07.005
    • (2011) Gastroenterology , vol.141 , pp. 1323-1333
    • Ye, D.1    Guo, S.2    Al-Sadi, R.3    Ma, T.Y.4
  • 75
    • 79959362128 scopus 로고    scopus 로고
    • NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
    • Zhao, J. L., Rao, D. S., Boldin, M. P., Taganov, K. D., O'Connell, R. M., and Baltimore, D. (2011). NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc. Natl. Acad. Sci. U.S.A. 108, 9184-9189. doi: 10.1073/pnas.1105398108
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 9184-9189
    • Zhao, J.L.1    Rao, D.S.2    Boldin, M.P.3    Taganov, K.D.4    O'Connell, R.M.5    Baltimore, D.6
  • 76
    • 84879060116 scopus 로고    scopus 로고
    • MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice
    • Zhao, J. L., Rao, D. S., O'Connell, R. M., Garcia-Flores, Y., and Baltimore, D. (2013). MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice. Elife 2, e00537. doi: 10.7554/eLife.00537
    • (2013) Elife , vol.2
    • Zhao, J.L.1    Rao, D.S.2    O'Connell, R.M.3    Garcia-Flores, Y.4    Baltimore, D.5
  • 77
    • 84882703646 scopus 로고    scopus 로고
    • The gut microbiota and obesity: from correlation to causality
    • Zhao, L. (2013). The gut microbiota and obesity: from correlation to causality. Nat. Rev. Microbiol. 11, 639-647. doi: 10.1038/nrmicro3089
    • (2013) Nat. Rev. Microbiol. , vol.11 , pp. 639-647
    • Zhao, L.1


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