Autoimmunity and chronic inflammation - Two clearance-related steps in the etiopathogenesis of SLE

Autoimmunity Reviews

Volumn 10, Issue 1, 2010, Pages 38-42

  Muñoz, Luis E ^a   Janko, Christina ^a   Schulze, Connie ^a   Schorn, Christine ^a   Sarter, Kerstin ^a   Schett, Georg ^a   Herrmann, Martin ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Apoptosis; Autoimmunity; Clearance; Inflammation; Systemic lupus erythematosus

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIGEN; CYTOKINE; DOUBLE STRANDED DNA;

ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; AUTOIMMUNITY; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; LYMPHOID TISSUE; MACROPHAGE; PHAGOCYTE; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS;

APOPTOSIS; AUTOIMMUNITY; HUMANS; INFLAMMATION; LUPUS ERYTHEMATOSUS, SYSTEMIC; METABOLIC CLEARANCE RATE;

EID: 78149360607     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2010.08.015     Document Type: Review

References (35)

1. Hahn B.H. Overview of pathogenesis of systemic lupus erythematosus. Dubois' lupus erythematosus 2007, 1414. Lippincott Williams & Wilkins, Philadelphia. Seventh ed. D.J. Wallace, B.H. Hahn (Eds.).
2. Tan E.M., Cohen A.S., Fries J.F., Masi A.T., McShane D.J., Rothfield N.F., et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982 Nov, 25(11):1271-1277.
3. Tutuncu Z.N., Kalunian K.C. The definition and classification of systemic lupus erythematosus. Dubois' lupus erythematosus 2007, 1414. Lippincott Williams & Wilkins, Philadelphia. Seventh ed. D.J. Wallace, B.H. Hahn (Eds.).
4. Rhodes B., Vyse T.J. The genetics of SLE: an update in the light of genome-wide association studies. Rheumatology (Oxford) 2008 Nov, 47(11):1603-1611.
5. Hargraves M., Richmond H., Morton R. Presentation of two bone marrow elements; the 'tart' cell and 'LE' cell. Proc Staff Meet Mayo Clin 1948, 23:25-28.
6. Hargraves M. Production in vitro of the LE cell phenomenon: use of normal bone marrow elements and blood plasma from patients with acute disseminated lupus erythematosus. Proc Staff Meet Mayo Clin 1949, 24:234-237.
7. Haserick J., Bortz D. Normal bone marrow inclusion phenomena induced by lupus erythematosus plasma. J Invest Dermantol 1949, 13:47-49.
8. Benedek T.G. Historical background of discoid and systemic lupus erythematosus. Dubois' lupus erythematosus 2007, 1414. Lippincott Williams & Wilkins, Philadelphia. Seventh ed. D.J. Wallace, B.H. Hahn (Eds.).
9. Klemperer P. The pathogenesis of lupus erythematosus and allied conditions. Ann Intern Med 1948 Jan, 28(1):1-11.
10. Casciola-Rosen L.A., Anhalt G., Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994, 179(4):1317-1330.
11. Herrmann M., Voll R.E., Zoller O.M., Hagenhofer M., Ponner B.B., Kalden J.R. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998 Jul, 41(7):1241-1250.
12. Baumann I., Kolowos W., Voll R.E., Manger B., Gaipl U., Neuhuber W.L., et al. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. Arthritis Rheum 2002 Jan, 46(1):191-201.
13. Lorenz H.M., Grunke M., Hieronymus T., Herrmann M., Kuhnel A., Manger B., et al. In vitro apoptosis and expression of apoptosis-related molecules in lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases. Arthritis Rheum 1997 Feb, 40(2):306-317.
14. Gaipl U.S., Munoz L.E., Grossmayer G., Lauber K., Franz S., Sarter K., et al. Clearance deficiency and systemic lupus erythematosus (SLE). J Autoimmun 2007, 28(2-3):114-121. Mar-May.
15. Cairns A.P., Crockard A.D., McConnell J.R., Courtney P.A., Bell A.L. Reduced expression of CD44 on monocytes and neutrophils in systemic lupus erythematosus: relations with apoptotic neutrophils and disease activity. Ann Rheum Dis 2001 Oct, 60(10):950-955.
16. Shoshan Y., Shapira I., Toubi E., Frolkis I., Yaron M., Mevorach D. Accelerated Fas-mediated apoptosis of monocytes and maturing macrophages from patients with systemic lupus erythematosus: relevance to in vitro impairment of interaction with iC3b-opsonized apoptotic cells. J Immunol 2001 Nov 15, 167(10):5963-5969.
17. Grossmayer G.E., Munoz L.E., Gaipl U.S., Franz S., Sheriff A., Voll R.E., et al. Removal of dying cells and systemic lupus erythematosus. Mod Rheumatol 2005, 15(6):383-390.
18. Munoz L.E., Janko C., Grossmayer G.E., Frey B., Voll Kern R.E, Kern P., et al. Remnants of Secondarily Necrotic Cells Fuel Inflammation in Systemic Lupus Erythematosus. Arthritis and Rheumatism 2009, 60(6):1733-1742.
19. Kuhn A., Herrmann M., Kleber S., Beckmann-Welle M., Fehsel K., Martin-Villalba A., et al. Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation. Arthritis Rheum 2006 Mar, 54(3):939-950.
20. Ren Y., Tang J., Mok M.Y., Chan A.W., Wu A., Lau C.S. Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum 2003 Oct, 48(10):2888-2897.
21. Gaipl U.S., Beyer T.D., Heyder P., Kuenkele S., Bottcher A., Voll R.E., et al. Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin. Arthritis Rheum 2004 Feb, 50(2):640-649.
22. Sherer Y., Gorstein A., Fritzler M.J., Shoenfeld Y. Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients. Semin Arthritis Rheum 2004 Oct, 34(2):501-537.
23. Winkler T.H., Fehr H., Kalden J.R. Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas. Eur J Immunol 1992 Jul, 22(7):1719-1728.
24. Wellmann U., Letz M., Herrmann M., Angermuller S., Kalden J.R., Winkler T.H. The evolution of human anti-double-stranded DNA autoantibodies. Proc Natl Acad Sci USA 2005 Jun 28, 102(26):9258-9263.
25. Wardemann H., Yurasov S., Schaefer A., Young J.W., Meffre E., Nussenzweig M.C. Predominant autoantibody production by early human B cell precursors. Science 2003 Sep 5, 301(5638):1374-1377.
26. Deng H., Apple R., Clare-Salzler M., Trembleau S., Mathis D., Adorini L., et al. Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease. J Exp Med 1993 Nov 1, 178(5):1675-1680.
27. Kuenkele S., Beyer T.D., Voll R.E., Kalden J.R., Herrmann M. Impaired clearance of apoptotic cells in systemic lupus erythematosus: challenge of T and B cell tolerance. Curr Rheumatol Rep 2003 Jun, 5(3):175-177.
28. Sarmiento L.F., Munoz L.E., Chirinos P., Bianco N.E., Zabaleta-Lanz M.E. Opsonization by anti-dsDNA antibodies of apoptotic cells in systemic lupus erythematosus. Autoimmunity 2007 Jun, 40(4):337-339.
29. Grossmayer G.E., Munoz L.E., Weber C.K., Franz S., Voll R.E., Kern P.M., et al. IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera. Ann Rheum Dis 2008 Nov, 67(11):1626-1632.
30. Frisoni L., McPhie L., Kang S.A., Monestier M., Madaio M., Satoh M., et al. Lack of chromatin and nuclear fragmentation in vivo impairs the production of lupus anti-nuclear antibodies. J Immunol 2007 Dec 1, 179(11):7959-7966.
31. Crow M.K., Kirou K.A. Interferon-alpha in systemic lupus erythematosus. Curr Opin Rheumatol 2004 Sep, 16(5):541-547.
32. Vallin H., Perers A., Alm G.V., Ronnblom L. Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus. J Immunol 1999 Dec 1, 163(11):6306-6313.
33. Lovgren T., Eloranta M.L., Bave U., Alm G.V., Ronnblom L. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 2004 Jun, 50(6):1861-1872.
34. Blanco P., Palucka A.K., Gill M., Pascual V., Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 2001 Nov 16, 294(5546):1540-1543.
35. Rahman A.H., Eisenberg R.A. The role of toll-like receptors in systemic lupus erythematosus. Springer Semin Immunopathol 2006 Oct, 28(2):131-143.