메뉴 건너뛰기




Volumn 2, Issue 9, 2001, Pages 802-809

The genetics of complex autoimmune diseases: Non-MHC susceptibility genes

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALLELE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DISEASE COURSE; ENVIRONMENTAL FACTOR; GENE CLUSTER; GENE IDENTIFICATION; GENE INTERACTION; GENE LOCATION; GENE SEQUENCE; GENETIC EPISTASIS; GENETIC HETEROGENEITY; GENETIC IDENTIFICATION; GENETIC ORGANIZATION; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MULTIGENE FAMILY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT;

EID: 0035555022     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni0901-802     Document Type: Review
Times cited : (339)

References (109)
  • 3
    • 0027375302 scopus 로고
    • Twin concordance rates for rheumatoid arthritis: Results from a nationwide study
    • (1993) Br. J. Rheumatol , vol.32 , pp. 903-907
    • Silman, A.J.1
  • 5
    • 0027933734 scopus 로고
    • A genome-wide search for human type I diabetes susceptibility genes
    • (1994) Nature , vol.371 , pp. 130-136
    • Davies, J.L.1
  • 6
    • 4243900937 scopus 로고    scopus 로고
    • Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome I q in african-american pedigrees
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 14869-14874
    • Moser, K.L.1
  • 7
    • 17144452354 scopus 로고    scopus 로고
    • A search for type I diabetes susceptibility genes in families from the United Kingdom
    • (1998) Nature Genet , vol.19 , pp. 297-300
    • Mein, C.A.1
  • 8
    • 0029314872 scopus 로고
    • Linkage and association between insulin-dependent diabetes mellitus (IDDM) susceptibility and markers near the glucokinase gene on chromosome 7
    • (1995) Nature Genet , vol.10 , pp. 240-242
    • Rowe, R.E.1
  • 9
    • 0035069106 scopus 로고    scopus 로고
    • A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases
    • (2001) Am. J. Hum. Genet , vol.68 , pp. 927-936
    • Jawaheer, D.1
  • 11
    • 0033029712 scopus 로고    scopus 로고
    • Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families
    • (1999) Hum. Mol. Genet , vol.8 , pp. 639-644
    • Shai, R.1
  • 12
    • 9244244764 scopus 로고    scopus 로고
    • Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8
    • (1996) Hum. Mol. Genet , vol.5 , pp. 693-698
    • Luo, D.F.1
  • 13
    • 17344372511 scopus 로고    scopus 로고
    • A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus
    • (1998) Nature Genet , vol.19 , pp. 292-296
    • Concannon, P.1
  • 14
    • 15844368830 scopus 로고    scopus 로고
    • A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
    • (1996) Nature Genet , vol.13 , pp. 464-468
    • Sawcer, S.1
  • 16
    • 0029866721 scopus 로고    scopus 로고
    • Fc γ RIIA alleles are heritable risk factors for lupus nephritis in African Americans
    • (1996) J. Clin. Invest , vol.97 , pp. 1348-1354
    • Salmon, J.E.1
  • 17
    • 0029553248 scopus 로고
    • Genetic and immunological markers of insulin dependent diabetes in Black Americans
    • (1995) Autoimmunity , vol.22 , pp. 27-32
    • Leech, N.J.1
  • 18
    • 0033848380 scopus 로고    scopus 로고
    • A susceptibility locus for human systemic lupus erythematosus (hSLEI) on chromosome 2q
    • (2000) J. Autoimmunity , vol.14 , pp. 169-178
    • Lindqvist, A.K.1
  • 22
    • 0031689094 scopus 로고    scopus 로고
    • Genetic linkage analysis of collagen-induced arthritis in the mouse
    • (1998) Eur. J. Immunol , vol.28 , pp. 3321-3328
    • Jirholt, J.1
  • 24
    • 0033853488 scopus 로고    scopus 로고
    • Derivation of diabetes-resistant congenic lines from the nonobese diabetic mouse
    • (2000) Clin. Immunol , vol.96 , pp. 119-130
    • McDuffie, M.1
  • 26
    • 0032530694 scopus 로고    scopus 로고
    • Multiple lupus susceptibility loci map to chromosome I in BXSB mice
    • (1998) J. Immunol , vol.161 , pp. 2753-2761
    • Hogarth, M.B.1
  • 27
    • 0033647280 scopus 로고    scopus 로고
    • Genome scan of human systemic lupus erythematosus by regression modeling: Evidence of linkage and epistasis at 4p16-15.2
    • (2000) Am. J. Hum. Genet , vol.67 , pp. 1460-1469
    • Gray, M.1
  • 28
    • 0027245603 scopus 로고
    • Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice
    • (1993) Science , vol.260 , pp. 695-698
    • Prins, J.-B.1
  • 29
    • 0029011132 scopus 로고
    • Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis
    • (1995) Nature Genet , vol.10 , pp. 313-317
    • Sundvall, M.1
  • 30
    • 0034612320 scopus 로고    scopus 로고
    • Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 6670-6675
    • Morel, L.1
  • 34
    • 0027172544 scopus 로고
    • Polygenic control of autoimmune diabetes in nonobese diabetic mice
    • (1993) Nature Genet , vol.4 , pp. 404-409
    • Ghosh, S.1
  • 36
    • 0033059667 scopus 로고    scopus 로고
    • Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
    • (1999) Nature Med , vol.5 , pp. 694-697
    • Bickerstaff, M.C.1
  • 37
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fc(γ)RIIB-deficient mice results from strain-specific epistasis
    • (2000) Immunity , vol.13 , pp. 277-285
    • Bolland, S.1    Ravetch, J.V.2
  • 38
    • 0031778836 scopus 로고    scopus 로고
    • Homozygous CIq deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    • (1998) Nature Genet , vol.19 , pp. 56-59
    • Botto, M.1
  • 39
    • 0027336832 scopus 로고
    • An MRL/MpJ-lpr/lpr substrain with a limited expansion of lpr double-negative T cells and a reduced autoimmune syndrome
    • (1993) Int. Immunol , vol.5 , pp. 525-532
    • Fossati, L.1
  • 41
    • 0018935099 scopus 로고
    • Epidemiologic contributions to multiple sclerosis: An overview
    • (1980) Neurology , vol.30 , pp. 61-79
    • Kurtzke, J.F.1
  • 46
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • (1996) Cell , vol.85 , pp. 303-306
    • Kotzin, B.1
  • 50
    • 0033511928 scopus 로고    scopus 로고
    • Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers
    • (1999) Arthritis Rheum , vol.42 , pp. 1782-1783
    • Harley, J.B.1    James, J.A.2
  • 51
    • 0031465706 scopus 로고    scopus 로고
    • An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus
    • (1997) J. Clin. Invest , vol.100 , pp. 3019-3026
    • James, J.A.1
  • 52
    • 0025787852 scopus 로고
    • A protective role of the environment in the development of type I diabetes?
    • (1991) Diabetes Med , vol.8 , pp. 906-910
    • Todd, J.A.1
  • 55
    • 0000386296 scopus 로고
    • An analysis of variability in number of digits in an inbred strain of guinea pigs
    • (1933) Genetics , vol.19 , pp. 506-536
    • Wright, S.1
  • 56
    • 0027428494 scopus 로고
    • Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: Application to nonobese diabetic (NOD) mouse and human insulin-dependent diabetes mellitus (IDDM)
    • (1993) Am. J. Hum. Genet , vol.53 , pp. 702-714
    • Risch, N.1    Ghosh, S.2    Todd, J.A.3
  • 57
    • 0029021388 scopus 로고
    • Crosses of NOD mice with the related NON strain: A polygenic model for type I diabetes
    • (1995) Diabetes , vol.44 , pp. 1186-1195
    • McAleer, M.A.1
  • 58
    • 0028942144 scopus 로고
    • Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner
    • (1995) J. Immunol , vol.154 , pp. 2441-2447
    • Drake, C.G.1
  • 60
    • 0346599403 scopus 로고    scopus 로고
    • An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. The Finnish-German APECED Consortium. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
    • (1997) Nature Genet , vol.17 , pp. 399-403
  • 62
    • 0033918564 scopus 로고    scopus 로고
    • The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes
    • (2000) Nature Genet , vol.25 , pp. 320-323
    • Eaves, I.A.1
  • 64
    • 0032990407 scopus 로고    scopus 로고
    • Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
    • (1999) Nature Genet , vol.22 , pp. 239-247
    • Halushka, M.K.1
  • 65
    • 0032991552 scopus 로고    scopus 로고
    • Characterization of single-nucleotide polymorphisms in coding regions of human genes
    • (1999) Nature Genet , vol.22 , pp. 231-238
    • Cargill, M.1
  • 67
    • 0034049641 scopus 로고    scopus 로고
    • Genetic and physical mapping of a type I diabetes susceptibility gene (IDDMI2) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33
    • (2000) Diabetes , vol.49 , pp. 492-499
    • Marron, M.P.1
  • 68
    • 8544274482 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups
    • (1997) Hum. Mol. Genet , vol.6 , pp. 1275-1282
    • Marron, M.P.1
  • 69
    • 0034121119 scopus 로고    scopus 로고
    • PARP alleles and SLE: Failure to confirm association with disease susceptibility
    • (2000) J. Clin. Invest , vol.105 , pp. 1501-1502
    • Criswell, L.A.1
  • 72
    • 16944366697 scopus 로고    scopus 로고
    • Insulin VNTR allele-specific effect in type I diabetes depends on identity of untransmitted paternal allele
    • The IMDIAB Group
    • (1997) Nature Genet , vol.17 , pp. 350-352
    • Bennett, S.T.1
  • 73
    • 18244421874 scopus 로고    scopus 로고
    • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type I diabetes
    • (1997) Nature Genet , vol.15 , pp. 293-297
    • Pugliese, A.1
  • 78
    • 0034618113 scopus 로고    scopus 로고
    • A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo
    • (2000) J. Exp. Med , vol.192 , pp. 359-366
    • Taylor, P.R.1
  • 79
    • 0031884284 scopus 로고    scopus 로고
    • Immune complex glomerulonephritis in C4- and C3-deficient mice
    • (1998) Kidney Int , vol.53 , pp. 320-330
    • Quigg, R.1
  • 80
    • 0032211714 scopus 로고    scopus 로고
    • A critical role for complement in maintenance of self-tolerance
    • (1998) Immunity , vol.9 , pp. 721-731
    • Prodeus, A.P.1
  • 81
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1
  • 82
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1
  • 84
    • 0034075807 scopus 로고    scopus 로고
    • Congenic mapping of the type I diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: Identification of a candidate segment of ancestral DNA by haplotype mapping
    • (2000) Genome Res , vol.10 , pp. 446-453
    • Lyons, P.A.1
  • 90
    • 0031914643 scopus 로고    scopus 로고
    • Subcongenic analysis of the Idd 13 locus in NOD/Lt mice: Evidence for several susceptibility genes including a possible diabetogenic role for β2-microglobulin
    • (1998) J. Immunol , vol.160 , pp. 1472-1478
    • Serreze, D.V.1
  • 91
    • 0029360374 scopus 로고
    • Mapping the diabetes polygene Idd3 on mouse chromosome 3 by use of novel congenic strains
    • (1995) Mamm. Genome , vol.6 , pp. 563-570
    • Lord, C.J.1
  • 92
    • 0033933070 scopus 로고    scopus 로고
    • Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type I diabetes gene?
    • (2000) Cytokine , vol.12 , pp. 477-482
    • Podolin, P.L.1
  • 93
    • 0033850819 scopus 로고    scopus 로고
    • Analysis of the mouse CD30 gene: A candidate for the NOD mouse type I diabetes locus Idd9.2
    • (2000) Diabetes , vol.49 , pp. 1612-1616
    • Siegmund, T.1
  • 94
    • 0033711184 scopus 로고    scopus 로고
    • The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137
    • (2000) Immunity , vol.13 , pp. 107-115
    • Lyons, P.A.1
  • 96
    • 0033032379 scopus 로고    scopus 로고
    • Comparative genetics of type I diabetes and autoimmune disease: Common loci, common pathways?
    • (1999) Diabetes , vol.48 , pp. 1353-1358
    • Becker, K.G.1
  • 98
    • 0031571223 scopus 로고    scopus 로고
    • Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd 10, localizes two genes mediating the Idd 10 effect and eliminates the candidate Fcrgl
    • (1997) J. Immunol , vol.159 , pp. 1835-1843
    • Podolin, P.L.1
  • 100
    • 0033820560 scopus 로고    scopus 로고
    • NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMPI loci in humans
    • (2000) Diabetes , vol.49 , pp. 1744-1747
    • Hill, N.J.1
  • 101
    • 0033566664 scopus 로고    scopus 로고
    • Cutting edge: Homologous recombination of the MHC class I K region defines new MHC-linked diabetogenic susceptibility gene(s) in nonobese diabetic mice
    • (1999) J. Immunol , vol.163 , pp. 1721-1724
    • Hattori, M.1
  • 102
    • 7144263739 scopus 로고    scopus 로고
    • Localization of two insulin-dependent diabetes (Idd) genes to Idd 10 region on mouse chromosome 3
    • (1998) Mamm. Genome , vol.9 , pp. 283-286
    • Podolin, P.L.1
  • 103
    • 0035895502 scopus 로고    scopus 로고
    • The human transcriptome map: Clustering of highly expressed genes in chromosomal domains
    • (2001) Science , vol.291 , pp. 1289-1292
    • Caron, H.1
  • 104
    • 18844476167 scopus 로고    scopus 로고
    • Functional identification of the mouse circadian clock gene by transgenic BAC rescue
    • (1997) Cell , vol.89 , pp. 655-667
    • Antoch, M.P.1
  • 105
    • 17644442703 scopus 로고    scopus 로고
    • Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene
    • (1998) Science , vol.280 , pp. 1447-1451
    • Probst, F.J.1
  • 106
    • 0033550904 scopus 로고    scopus 로고
    • Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type I diabetes: Prospective twin study
    • (1999) Br. Med. J , vol.318 , pp. 698-702
    • Redondo, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.