Neurotrophic and neuroprotective properties of exendin-4 in adult rat dorsal root ganglion neurons: involvement of insulin and RhoA

Histochemistry and Cell Biology

Volumn 144, Issue 3, 2015, Pages 249-259

  Tsukamoto, Masami ^a,b   Niimi, Naoko ^a   Sango, Kazunori ^a   Takaku, Shizuka ^a   Kanazawa, Yasushi ^a,b   Utsunomiya, Kazunori ^b  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adult DRG neurons; Exendin 4; GLP 1 receptor; Insulin; Neurite outgrowth; PI3 kinase inhibitor; RhoA; Survival

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; EXENDIN 4; INSULIN; NEUROPROTECTIVE AGENT; NEUROTROPHIC FACTOR; PROTEOCHONDROITIN SULFATE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR; MORPHOLINE DERIVATIVE; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; VENOM;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; CELL REGENERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME REPRESSION; FEMALE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEFICIENCY; NERVE FIBER GROWTH; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; SPINAL GANGLION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; NERVE CELL; NEURITE; PC12 CELL LINE; PHYSIOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; FEMALE; GANGLIA, SPINAL; GLUCAGON-LIKE PEPTIDE 1; INSULIN; MORPHOLINES; NEURITES; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; PEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, WISTAR; RECEPTORS, GLUCAGON; RHOA GTP-BINDING PROTEIN; VENOMS;

EID: 84939270100     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-015-1333-3     Document Type: Article

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