-
1
-
-
0033304603
-
The glucagon-like peptides.
-
Kieffer TJ, Habener JF. The glucagon-like peptides. Endocr Rev 1999; 20: 876-913.
-
(1999)
Endocr Rev
, vol.20
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
2
-
-
7444228521
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes.
-
Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2628-2635.
-
(2004)
Diabetes Care
, vol.27
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
3
-
-
53249142132
-
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study.
-
Drucker DJ, Buse JB, Taylor K et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 2008; 372: 1240-1250.
-
(2008)
Lancet
, vol.372
, pp. 1240-1250
-
-
Drucker, D.J.1
Buse, J.B.2
Taylor, K.3
-
4
-
-
1842598583
-
Glucagon-like peptide 1 improved glycemic control in type 1 diabetes.
-
Behme MT, Dupre J, McDonald TJ. Glucagon-like peptide 1 improved glycemic control in type 1 diabetes. BMC Endocr Disord 2003; 3: 3.
-
(2003)
BMC Endocr Disord
, vol.3
, pp. 3
-
-
Behme, M.T.1
Dupre, J.2
McDonald, T.J.3
-
5
-
-
70450170211
-
Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists.
-
Kielgast U, Holst JJ, Madsbad S. Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists. Curr Diabetes Rev 2009; 5: 266-275.
-
(2009)
Curr Diabetes Rev
, vol.5
, pp. 266-275
-
-
Kielgast, U.1
Holst, J.J.2
Madsbad, S.3
-
6
-
-
0029954211
-
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.
-
Creutzfeldt WO, Kleine N, Willms B, Orskov C, Holst JJ, Nauck MA. Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients. Diabetes Care 1996; 19: 580-586.
-
(1996)
Diabetes Care
, vol.19
, pp. 580-586
-
-
Creutzfeldt, W.O.1
Kleine, N.2
Willms, B.3
Orskov, C.4
Holst, J.J.5
Nauck, M.A.6
-
7
-
-
0026596851
-
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus.
-
Gutniak M, Orskov C, Holst JJ, Ahren B, Efendic S. Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med 1992; 326: 1316-1322.
-
(1992)
N Engl J Med
, vol.326
, pp. 1316-1322
-
-
Gutniak, M.1
Orskov, C.2
Holst, J.J.3
Ahren, B.4
Efendic, S.5
-
8
-
-
0027397282
-
Presence and characterization of glucagon-like peptide-1(7-36) amide receptors in solubilized membranes of rat adipose tissue.
-
Valverde I, Merida E, Delgado E, Trapote MA, Villanueva-Penacarrillo ML. Presence and characterization of glucagon-like peptide-1(7-36) amide receptors in solubilized membranes of rat adipose tissue. Endocrinology 1993; 132: 75-79.
-
(1993)
Endocrinology
, vol.132
, pp. 75-79
-
-
Valverde, I.1
Merida, E.2
Delgado, E.3
Trapote, M.A.4
Villanueva-Penacarrillo, M.L.5
-
9
-
-
0028139157
-
Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle.
-
Villanueva-Penacarrillo ML, Alcantara AI, Clemente F, Delgado E, Valverde I. Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle. Diabetologia 1994; 37: 1163-1166.
-
(1994)
Diabetologia
, vol.37
, pp. 1163-1166
-
-
Villanueva-Penacarrillo, M.L.1
Alcantara, A.I.2
Clemente, F.3
Delgado, E.4
Valverde, I.5
-
11
-
-
0031930092
-
Signalling pathways involved in the stimulation of glycogen synthesis by insulin in rat hepatocytes.
-
Peak M, Rochford JJ, Borthwick AC, Yeaman SJ, Agius L. Signalling pathways involved in the stimulation of glycogen synthesis by insulin in rat hepatocytes. Diabetologia 1998; 41: 16-25.
-
(1998)
Diabetologia
, vol.41
, pp. 16-25
-
-
Peak, M.1
Rochford, J.J.2
Borthwick, A.C.3
Yeaman, S.J.4
Agius, L.5
-
12
-
-
0038445987
-
Cell signalling of the GLP-1 action in rat liver.
-
Redondo A, Trigo MV, Acitores A, Valverde I, Villanueva-Penacarrillo ML. Cell signalling of the GLP-1 action in rat liver. Mol Cell Endocrinol 2003; 204: 43-50.
-
(2003)
Mol Cell Endocrinol
, vol.204
, pp. 43-50
-
-
Redondo, A.1
Trigo, M.V.2
Acitores, A.3
Valverde, I.4
Villanueva-Penacarrillo, M.L.5
-
13
-
-
77953160144
-
Minireview: update on incretin biology: focus on glucagon-like peptide-1.
-
Brubaker PL. Minireview: update on incretin biology: focus on glucagon-like peptide-1. Endocrinology 2010; 151: 1984-1989.
-
(2010)
Endocrinology
, vol.151
, pp. 1984-1989
-
-
Brubaker, P.L.1
-
14
-
-
77649102941
-
Effects of incretin hormones on beta-cell mass and function, body weight, and hepatic and myocardial function.
-
Mudaliar S, Henry RR. Effects of incretin hormones on beta-cell mass and function, body weight, and hepatic and myocardial function. Am J Med 2010; 123: S19-27.
-
(2010)
Am J Med
, vol.123
-
-
Mudaliar, S.1
Henry, R.R.2
-
15
-
-
0036721026
-
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.
-
Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH. Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4. J Pharmacol Exp Ther 2002; 302: 881-888.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 881-888
-
-
Perry, T.1
Haughey, N.J.2
Mattson, M.P.3
Egan, J.M.4
Greig, N.H.5
-
16
-
-
0036182251
-
A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells.
-
Perry T, Lahiri DK, Chen D et al. A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells. J Pharmacol Exp Ther 2002; 300: 958-966.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 958-966
-
-
Perry, T.1
Lahiri, D.K.2
Chen, D.3
-
17
-
-
0038248960
-
Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.
-
Perry T, Lahiri DK, Sambamurti K et al. Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron. J Neurosci Res 2003; 72: 603-612.
-
(2003)
J Neurosci Res
, vol.72
, pp. 603-612
-
-
Perry, T.1
Lahiri, D.K.2
Sambamurti, K.3
-
18
-
-
38849196303
-
Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease.
-
Bertilsson G, Patrone C, Zachrisson O et al. Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. J Neurosci Res 2008; 86: 326-338.
-
(2008)
J Neurosci Res
, vol.86
, pp. 326-338
-
-
Bertilsson, G.1
Patrone, C.2
Zachrisson, O.3
-
19
-
-
77953880083
-
Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease.
-
Holscher C. Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease. Recent Pat CNS Drug Discov 2010; 5: 109-117.
-
(2010)
Recent Pat CNS Drug Discov
, vol.5
, pp. 109-117
-
-
Holscher, C.1
-
20
-
-
63249091158
-
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.
-
Martin B, Golden E, Carlson OD et al. Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. Diabetes 2009; 58: 318-328.
-
(2009)
Diabetes
, vol.58
, pp. 318-328
-
-
Martin, B.1
Golden, E.2
Carlson, O.D.3
-
21
-
-
33846501672
-
Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy.
-
Perry T, Holloway HW, Weerasuriya A et al. Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy. Exp Neurol 2007; 203: 293-301.
-
(2007)
Exp Neurol
, vol.203
, pp. 293-301
-
-
Perry, T.1
Holloway, H.W.2
Weerasuriya, A.3
-
22
-
-
2942709609
-
Modeling diabetic sensory neuropathy in rats.
-
Calcutt NA. Modeling diabetic sensory neuropathy in rats. Methods Mol Med 2004; 99: 55-65.
-
(2004)
Methods Mol Med
, vol.99
, pp. 55-65
-
-
Calcutt, N.A.1
-
23
-
-
48749104018
-
Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice.
-
Beiswenger KK, Calcutt NA, Mizisin AP. Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice. Neurosci Lett 2008; 442: 267-272.
-
(2008)
Neurosci Lett
, vol.442
, pp. 267-272
-
-
Beiswenger, K.K.1
Calcutt, N.A.2
Mizisin, A.P.3
-
24
-
-
49749113817
-
Expression of the GLP-1 receptor in mouse, rat, and human pancreas.
-
Tornehave D, Kristensen P, Romer J, Knudsen LB, Heller RS. Expression of the GLP-1 receptor in mouse, rat, and human pancreas. J Histochem Cytochem 2008; 56: 841-851.
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 841-851
-
-
Tornehave, D.1
Kristensen, P.2
Romer, J.3
Knudsen, L.B.4
Heller, R.S.5
-
25
-
-
0028900758
-
Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences.
-
Wei Y, Mojsov S. Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences. FEBS Lett 1995; 358: 219-224.
-
(1995)
FEBS Lett
, vol.358
, pp. 219-224
-
-
Wei, Y.1
Mojsov, S.2
-
26
-
-
80054051051
-
-
Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats. Br J Pharmacol 2011 [Epub ahead of print].
-
Liu WJ, Jin HY, Lee KA, Xie SH, Baek HS, Park TS. Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats. Br J Pharmacol 2011 [Epub ahead of print].
-
-
-
Liu, W.J.1
Jin, H.Y.2
Lee, K.A.3
Xie, S.H.4
Baek, H.S.5
Park, T.S.6
-
27
-
-
78650002982
-
GLP-1: What is known, new and controversial in 2010?
-
Burcelin R, Dejager S. GLP-1: What is known, new and controversial in 2010? Diabetes Metab 2010; 36: 503-509.
-
(2010)
Diabetes Metab
, vol.36
, pp. 503-509
-
-
Burcelin, R.1
Dejager, S.2
-
28
-
-
34748898831
-
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats.
-
Vahl TP, Tauchi M, Durler TS et al. Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology 2007; 148: 4965-4973.
-
(2007)
Endocrinology
, vol.148
, pp. 4965-4973
-
-
Vahl, T.P.1
Tauchi, M.2
Durler, T.S.3
-
29
-
-
77950352189
-
GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.
-
Li Y, Duffy KB, Ottinger MA et al. GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. J Alzheimers Dis 2010; 19: 1205-1219.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 1205-1219
-
-
Li, Y.1
Duffy, K.B.2
Ottinger, M.A.3
-
30
-
-
59049087723
-
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
-
Li Y, Perry T, Kindy MS et al. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proc Natl Acad Sci USA 2009; 106: 1285-1290.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1285-1290
-
-
Li, Y.1
Perry, T.2
Kindy, M.S.3
-
31
-
-
48949088649
-
Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide-1.
-
Blandino-Rosano M, Perez-Arana G, Mellado-Gil JM, Segundo C, Aguilar-Diosdado M. Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide-1. J Mol Endocrinol 2008; 41: 35-44.
-
(2008)
J Mol Endocrinol
, vol.41
, pp. 35-44
-
-
Blandino-Rosano, M.1
Perez-Arana, G.2
Mellado-Gil, J.M.3
Segundo, C.4
Aguilar-Diosdado, M.5
-
32
-
-
33646182645
-
Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin.
-
List JF, He H, Habener JF. Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin. Regul Pept 2006; 134: 149-157.
-
(2006)
Regul Pept
, vol.134
, pp. 149-157
-
-
List, J.F.1
He, H.2
Habener, J.F.3
-
33
-
-
77953959949
-
Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.
-
Oeseburg H, de Boer RA, Buikema H, van der Harst P, van Gilst WH, Sillje HH. Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. Arterioscler Thromb Vasc Biol 2010; 30: 1407-1414.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1407-1414
-
-
Oeseburg, H.1
de Boer, R.A.2
Buikema, H.3
van der Harst, P.4
van Gilst, W.H.5
Sillje, H.H.6
-
34
-
-
77954384449
-
Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptor.
-
Erdogdu O, Nathanson D, Sjoholm A, Nystrom T, Zhang Q. Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptor. Mol Cell Endocrinol 2010; 325: 26-35.
-
(2010)
Mol Cell Endocrinol
, vol.325
, pp. 26-35
-
-
Erdogdu, O.1
Nathanson, D.2
Sjoholm, A.3
Nystrom, T.4
Zhang, Q.5
-
35
-
-
4344713643
-
Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia.
-
Degn KB, Brock B, Juhl CB et al. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia. Diabetes 2004; 53: 2397-2403.
-
(2004)
Diabetes
, vol.53
, pp. 2397-2403
-
-
Degn, K.B.1
Brock, B.2
Juhl, C.B.3
-
36
-
-
0032994663
-
Glucose-dependent stimulatory effect of glucagon-like peptide 1(7-36) amide on the electrical activity of pancreatic beta-cells recorded in vivo.
-
Fernandez J, Valdeolmillos M. Glucose-dependent stimulatory effect of glucagon-like peptide 1(7-36) amide on the electrical activity of pancreatic beta-cells recorded in vivo. Diabetes 1999; 48: 754-757.
-
(1999)
Diabetes
, vol.48
, pp. 754-757
-
-
Fernandez, J.1
Valdeolmillos, M.2
-
37
-
-
0033001088
-
Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy.
-
Fernyhough P, Gallagher A, Averill SA et al. Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy. Diabetes 1999; 48: 881-889.
-
(1999)
Diabetes
, vol.48
, pp. 881-889
-
-
Fernyhough, P.1
Gallagher, A.2
Averill, S.A.3
-
38
-
-
0035158585
-
A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy.
-
Purves T, Middlemas A, Agthong S et al. A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy. FASEB J 2001; 15: 2508-2514.
-
(2001)
FASEB J
, vol.15
, pp. 2508-2514
-
-
Purves, T.1
Middlemas, A.2
Agthong, S.3
-
39
-
-
24944490193
-
The ERK cascade: a prototype of MAPK signaling.
-
Rubinfeld H, Seger R. The ERK cascade: a prototype of MAPK signaling. Mol Biotechnol 2005; 31: 151-174.
-
(2005)
Mol Biotechnol
, vol.31
, pp. 151-174
-
-
Rubinfeld, H.1
Seger, R.2
-
40
-
-
65449151412
-
Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials.
-
Calcutt NA, Cooper ME, Kern TS, Schmidt AM. Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials. Nat Rev Drug Discov 2009; 8: 417-429.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 417-429
-
-
Calcutt, N.A.1
Cooper, M.E.2
Kern, T.S.3
Schmidt, A.M.4
-
41
-
-
0037329984
-
Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy.
-
Calcutt NA, Allendoerfer KL, Mizisin AP et al. Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy. J Clin Invest 2003; 111: 507-514.
-
(2003)
J Clin Invest
, vol.111
, pp. 507-514
-
-
Calcutt, N.A.1
Allendoerfer, K.L.2
Mizisin, A.P.3
-
42
-
-
71649102751
-
Effect of dipeptidyl peptidase-IV (DPP-IV) inhibitor (Vildagliptin) on peripheral nerves in streptozotocin-induced diabetic rats.
-
Jin HY, Liu WJ, Park JH, Baek HS, Park TS. Effect of dipeptidyl peptidase-IV (DPP-IV) inhibitor (Vildagliptin) on peripheral nerves in streptozotocin-induced diabetic rats. Arch Med Res 2009; 40: 536-544.
-
(2009)
Arch Med Res
, vol.40
, pp. 536-544
-
-
Jin, H.Y.1
Liu, W.J.2
Park, J.H.3
Baek, H.S.4
Park, T.S.5
-
43
-
-
54449091457
-
Early loss of peptidergic intraepidermal nerve fibers in an STZ-induced mouse model of insensate diabetic neuropathy.
-
Johnson MS, Ryals JM, Wright DE. Early loss of peptidergic intraepidermal nerve fibers in an STZ-induced mouse model of insensate diabetic neuropathy. Pain 2008; 140: 35-47.
-
(2008)
Pain
, vol.140
, pp. 35-47
-
-
Johnson, M.S.1
Ryals, J.M.2
Wright, D.E.3
-
44
-
-
4444292549
-
Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch.
-
Malmberg AB, Mizisin AP, Calcutt NA, von Stein T, Robbins WR, Bley KR. Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch. Pain 2004; 111: 360-367.
-
(2004)
Pain
, vol.111
, pp. 360-367
-
-
Malmberg, A.B.1
Mizisin, A.P.2
Calcutt, N.A.3
von Stein, T.4
Robbins, W.R.5
Bley, K.R.6
-
45
-
-
78651101592
-
Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments.
-
Tesfaye S, Boulton AJ, Dyck PJ et al. Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care 33: 2285-2293.
-
Diabetes Care
, vol.33
, pp. 2285-2293
-
-
Tesfaye, S.1
Boulton, A.J.2
Dyck, P.J.3
-
47
-
-
73649091056
-
ERK and cell death: ERK1/2 in neuronal death.
-
Subramaniam S, Unsicker K. ERK and cell death: ERK1/2 in neuronal death. FEBS J 2010; 277: 22-29.
-
(2010)
FEBS J
, vol.277
, pp. 22-29
-
-
Subramaniam, S.1
Unsicker, K.2
|