메뉴 건너뛰기




Volumn 62, Issue 5, 2013, Pages 1697-1708

Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; EXENDIN 4; GLUCOSE; GLYCOPROTEIN GP 91; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHO FACTOR; VILDAGLIPTIN;

EID: 84874931230     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1025     Document Type: Article
Times cited : (164)

References (50)
  • 1
    • 78650141628 scopus 로고    scopus 로고
    • Intensive glucose lowering and cardiovascular disease prevention in diabetes: Reconciling the recent clinical trial data
    • Mazzone T. Intensive glucose lowering and cardiovascular disease prevention in diabetes: reconciling the recent clinical trial data. Circulation 2010;122:2201-2211
    • (2010) Circulation , vol.122 , pp. 2201-2211
    • Mazzone, T.1
  • 3
    • 79952066868 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: From the pathophysiology of the cardiac myocytes to current diagnosis and management strategies
    • Voulgari C, Papadogiannis D, Tentolouris N. Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies. Vasc Health Risk Manag 2010;6:883-903
    • (2010) Vasc Health Risk Manag , vol.6 , pp. 883-903
    • Voulgari, C.1    Papadogiannis, D.2    Tentolouris, N.3
  • 4
    • 77955585592 scopus 로고    scopus 로고
    • Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: An analysis of the ACCORD randomised trial
    • ACCORD trial group
    • Ismail-Beigi F, Craven T, Banerji MA, et al.; ACCORD trial group. Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet 2010;376:419-430
    • (2010) Lancet , vol.376 , pp. 419-430
    • Ismail-Beigi, F.1    Craven, T.2    Banerji, M.A.3
  • 5
    • 79951670729 scopus 로고    scopus 로고
    • Amelioration effects of berberine on diabetic microendothelial injury model by the combination of high glucose and advanced glycation end products in vitro
    • Hao M, Li SY, Sun CK, et al. Amelioration effects of berberine on diabetic microendothelial injury model by the combination of high glucose and advanced glycation end products in vitro. Eur J Pharmacol 2011;654:320-325
    • (2011) Eur J Pharmacol , vol.654 , pp. 320-325
    • Hao, M.1    Li, S.Y.2    Sun, C.K.3
  • 6
    • 34248223285 scopus 로고    scopus 로고
    • Biology of Incretins: GLP-1 and GIP
    • DOI 10.1053/j.gastro.2007.03.054, PII S001650850700580X
    • Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007;132:2131-2157 (Pubitemid 46711096)
    • (2007) Gastroenterology , vol.132 , Issue.6 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 7
    • 79955608846 scopus 로고    scopus 로고
    • Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia
    • Lee CH, Yan B, Yoo KY, et al. Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia. J Neurosci Res 2011;89:1103-1113
    • (2011) J Neurosci Res , vol.89 , pp. 1103-1113
    • Lee, C.H.1    Yan, B.2    Yoo, K.Y.3
  • 8
    • 84863560602 scopus 로고    scopus 로고
    • Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction
    • Lønborg J, Vejlstrup N, Kelbæk H, et al. Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction. Eur Heart J 2012;33:1491-1499
    • (2012) Eur Heart J , vol.33 , pp. 1491-1499
    • Lønborg, J.1    Vejlstrup, N.2    Kelbæk, H.3
  • 10
    • 84859704429 scopus 로고    scopus 로고
    • The synergistic effect of valsartan and LAF237 [(S)-1-[(3-hydroxy-1- adamantyl)ammo]acetyl-2-cyanopyrrolidine] on vascular oxidative stress and inflammation in type 2 diabetic mice
    • Shen M, Sun D, Li W, et al. The synergistic effect of valsartan and LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] on vascular oxidative stress and inflammation in type 2 diabetic mice. Exp Diabetes Res 2012;2012:146194
    • (2012) Exp Diabetes Res , vol.2012 , pp. 146194
    • Shen, M.1    Sun, D.2    Li, W.3
  • 11
    • 84863392812 scopus 로고    scopus 로고
    • Stability and bioactivity studies on dipeptidyl peptidase IV resistant glucogan-like peptide-1 analogues
    • Chen W, Zhou Y, Zhang H, et al. Stability and bioactivity studies on dipeptidyl peptidase IV resistant glucogan-like peptide-1 analogues. Protein Pept Lett 2012;19:203-211
    • (2012) Protein Pept Lett , vol.19 , pp. 203-211
    • Chen, W.1    Zhou, Y.2    Zhang, H.3
  • 12
    • 80053515769 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: Avenues for a mechanistic-based therapeutic approach
    • Folli F, Corradi D, Fanti P, et al. The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach. Curr Diabetes Rev 2011;7:313-324
    • (2011) Curr Diabetes Rev , vol.7 , pp. 313-324
    • Folli, F.1    Corradi, D.2    Fanti, P.3
  • 13
    • 84856373232 scopus 로고    scopus 로고
    • Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress
    • Naudi A, Jove M, Ayala V, et al. Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress. Exp Diabetes Res 2012;2012:696215
    • (2012) Exp Diabetes Res , vol.2012 , pp. 696215
    • Naudi, A.1    Jove, M.2    Ayala, V.3
  • 14
    • 84863282319 scopus 로고    scopus 로고
    • C-reactive protein promotes adhesion of monocytes to endothelial cells via NADPH oxidase-mediated oxidative stress
    • Huang X, Zhang J, Liu J, et al. C-reactive protein promotes adhesion of monocytes to endothelial cells via NADPH oxidase-mediated oxidative stress. J Cell Biochem 2012;113:857-867
    • (2012) J Cell Biochem , vol.113 , pp. 857-867
    • Huang, X.1    Zhang, J.2    Liu, J.3
  • 15
    • 80053168230 scopus 로고    scopus 로고
    • Rho kinase inhibition by fasudil exerts antioxidant effects in hypercholesterolemic rats
    • Ma Z, Zhang J, Ji E, Cao G, Li G, Chu L. Rho kinase inhibition by fasudil exerts antioxidant effects in hypercholesterolemic rats. Clin Exp Pharmacol Physiol 2011;38:688-694
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 688-694
    • Ma, Z.1    Zhang, J.2    Ji, E.3    Cao, G.4    Li, G.5    Chu, L.6
  • 17
    • 84860332947 scopus 로고    scopus 로고
    • Cardioprotective effect of a combination of Rho-kinase inhibitor and p38 MAPK inhibitor on cardiovascular remodeling and oxidative stress in Dahl rats
    • Takeshima H, Kobayashi N, Koguchi W, Ishikawa M, Sugiyama F, Ishimitsu T. Cardioprotective effect of a combination of Rho-kinase inhibitor and p38 MAPK inhibitor on cardiovascular remodeling and oxidative stress in Dahl rats. J Atheroscler Thromb 2012;19:326-336
    • (2012) J Atheroscler Thromb , vol.19 , pp. 326-336
    • Takeshima, H.1    Kobayashi, N.2    Koguchi, W.3    Ishikawa, M.4    Sugiyama, F.5    Ishimitsu, T.6
  • 18
    • 77953536928 scopus 로고    scopus 로고
    • A PKC-beta inhibitor treatment reverses cardiac microvascular barrier dysfunction in diabetic rats
    • Wei L, Yin Z, Yuan Y, et al. A PKC-beta inhibitor treatment reverses cardiac microvascular barrier dysfunction in diabetic rats. Microvasc Res 2010;80:158-165
    • (2010) Microvasc Res , vol.80 , pp. 158-165
    • Wei, L.1    Yin, Z.2    Yuan, Y.3
  • 19
    • 84866113571 scopus 로고    scopus 로고
    • Short-term effects of sleeve gastrectomy and caloric restriction on blood pressure in diet-induced obese rats
    • Rodríguez A, Becerril S, Valentí V, et al. Short-term effects of sleeve gastrectomy and caloric restriction on blood pressure in diet-induced obese rats. Obes Surg 2012;22:1481-1490
    • (2012) Obes Surg , vol.22 , pp. 1481-1490
    • Rodríguez, A.1    Becerril, S.2    Valentí, V.3
  • 21
    • 84863044821 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice
    • Eguchi M, Kim YH, Kang KW, et al. Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice. PLoS ONE 2012;7:e30450
    • (2012) PLoS ONE , vol.7
    • Eguchi, M.1    Kim, Y.H.2    Kang, K.W.3
  • 22
    • 79955103642 scopus 로고    scopus 로고
    • Body distribution of C-methionine and FDG in rat measured by microPET
    • Stolc S, Jakubíková L, Kukurová I. Body distribution of C-methionine and FDG in rat measured by microPET. Interdiscip Toxicol 2011;4:52-55
    • (2011) Interdiscip Toxicol , vol.4 , pp. 52-55
    • Stolc, S.1    Jakubíková, L.2    Kukurová, I.3
  • 23
    • 77951665702 scopus 로고    scopus 로고
    • A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats
    • Wei L, Sun D, Yin Z, et al. A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats. Apoptosis 2010;15:488-498
    • (2010) Apoptosis , vol.15 , pp. 488-498
    • Wei, L.1    Sun, D.2    Yin, Z.3
  • 24
    • 84862489081 scopus 로고    scopus 로고
    • Effects of ghrelin on homocysteine-induced dysfunction and inflammatory response in rat cardiac microvascular endothelial cells
    • Wang D, Wang H, Luo P, et al. Effects of ghrelin on homocysteine-induced dysfunction and inflammatory response in rat cardiac microvascular endothelial cells. Cell Biol Int 2012;36:511-517
    • (2012) Cell Biol Int , vol.36 , pp. 511-517
    • Wang, D.1    Wang, H.2    Luo, P.3
  • 25
    • 77950508168 scopus 로고    scopus 로고
    • Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1
    • Schuhmacher S, Wenzel P, Schulz E, et al. Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1. Hypertension 2010;55:897-904
    • (2010) Hypertension , vol.55 , pp. 897-904
    • Schuhmacher, S.1    Wenzel, P.2    Schulz, E.3
  • 26
    • 79961137726 scopus 로고    scopus 로고
    • Particulate matter exposure exacerbates high glucose-induced cardiomyocyte dysfunction through ROS generation
    • Zuo L, Youtz DJ, Wold LE. Particulate matter exposure exacerbates high glucose-induced cardiomyocyte dysfunction through ROS generation. PLoS ONE 2011;6:e23116
    • (2011) PLoS ONE , vol.6
    • Zuo, L.1    Youtz, D.J.2    Wold, L.E.3
  • 27
    • 27144506185 scopus 로고    scopus 로고
    • The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
    • Koo SH, Flechner L, Qi L, et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 2005;437:1109-1111
    • (2005) Nature , vol.437 , pp. 1109-1111
    • Koo, S.H.1    Flechner, L.2    Qi, L.3
  • 29
    • 34247543921 scopus 로고    scopus 로고
    • Acute blood-brain barrier permeabilization in rats after systemic Phoneutria nigriventer venom
    • DOI 10.1016/j.brainres.2007.02.086, PII S0006899307004386
    • Rapôso C, Zago GM, da Silva GH, da Cruz Höfling MA. Acute blood-brain barrier permeabilization in rats after systemic Phoneutria nigriventer venom. Brain Res 2007;1149:18-29 (Pubitemid 46659894)
    • (2007) Brain Research , vol.1149 , Issue.1 , pp. 18-29
    • Raposo, C.1    Zago, G.M.2    Da, S.G.H.3    Da, M.A.4
  • 31
    • 84860390325 scopus 로고    scopus 로고
    • Incretin effect: GLP-1, GIP, DPP4
    • Kazafeos K. Incretin effect: GLP-1, GIP, DPP4. Diabetes Res Clin Pract 2011;93(Suppl 1):S32 -S36
    • (2011) Diabetes Res Clin Pract , vol.93 , Issue.SUPPL. 1
    • Kazafeos, K.1
  • 32
    • 84860158306 scopus 로고    scopus 로고
    • Current treatments and strategies for type 2 diabetes: Can we do better with GLP-1 receptor agonists?
    • Peterson G. Current treatments and strategies for type 2 diabetes: can we do better with GLP-1 receptor agonists? Ann Med 2012;44:338-349
    • (2012) Ann Med , vol.44 , pp. 338-349
    • Peterson, G.1
  • 33
    • 84861765116 scopus 로고    scopus 로고
    • Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: A randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono)
    • EFC6018 GetGoal-Mono Study Investigators
    • Fonseca VA, Alvarado-Ruiz R, Raccah D, Boka G, Miossec P, Gerich JE; EFC6018 GetGoal-Mono Study Investigators. Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono). Diabetes Care 2012;35:1225-1231
    • (2012) Diabetes Care , vol.35 , pp. 1225-1231
    • Fonseca, V.A.1    Alvarado-Ruiz, R.2    Raccah, D.3    Boka, G.4    Miossec, P.5    Gerich, J.E.6
  • 34
  • 35
    • 79959773411 scopus 로고    scopus 로고
    • DPP-4 inhibitors: Impact on glycemic control and cardiovascular risk factors
    • Dicker D. DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors. Diabetes Care 2011;34(Suppl. 2):S276-S278
    • (2011) Diabetes Care , vol.34 , Issue.SUPPL. 2
    • Dicker, D.1
  • 36
    • 0035340019 scopus 로고    scopus 로고
    • Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro
    • DOI 10.1053/meta.2001.22519
    • Parkes DG, Pittner R, Jodka C, Smith P, Young A. Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro. Metabolism 2001;50:583-589 (Pubitemid 32433049)
    • (2001) Metabolism: Clinical and Experimental , vol.50 , Issue.5 , pp. 583-589
    • Parkes, D.G.1    Pittner, R.2    Jodka, C.3    Smith, P.4    Young, A.5
  • 37
    • 83255176860 scopus 로고    scopus 로고
    • Beyond glucose lowering: Glucagon-like peptide-1 receptor agonists, body weight and the cardiovascular system
    • Vergès B, Bonnard C, Renard E. Beyond glucose lowering: glucagon-like peptide-1 receptor agonists, body weight and the cardiovascular system. Diabetes Metab 2011;37:477-488
    • (2011) Diabetes Metab , vol.37 , pp. 477-488
    • Vergès, B.1    Bonnard, C.2    Renard, E.3
  • 38
    • 12144260853 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury
    • DOI 10.2337/diabetes.54.1.146
    • Bose AK, Mocanu MM, Carr RD, Brand CL, Yellon DM. Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury. Diabetes 2005;54:146-151 (Pubitemid 40105106)
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 146-151
    • Bose, A.K.1    Mocanu, M.M.2    Carr, R.D.3    Brand, C.L.4    Yellon, D.M.5
  • 39
    • 77951151612 scopus 로고    scopus 로고
    • Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    • Arakawa M, Mita T, Azuma K, et al. Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4. Diabetes 2010;59:1030-1037
    • (2010) Diabetes , vol.59 , pp. 1030-1037
    • Arakawa, M.1    Mita, T.2    Azuma, K.3
  • 40
    • 70350520817 scopus 로고    scopus 로고
    • A simulation of the comparative long-term effectiveness of liraglutide and glimepiride monotherapies in patients with type 2 diabetes mellitus
    • Sullivan SD, Alfonso-Cristancho R, Conner C, Hammer M, Blonde L. A simulation of the comparative long-term effectiveness of liraglutide and glimepiride monotherapies in patients with type 2 diabetes mellitus. Pharmacotherapy 2009;29:1280-1288
    • (2009) Pharmacotherapy , vol.29 , pp. 1280-1288
    • Sullivan, S.D.1    Alfonso-Cristancho, R.2    Conner, C.3    Hammer, M.4    Blonde, L.5
  • 43
    • 80052269271 scopus 로고    scopus 로고
    • Does microvascular disease predict macrovascular events in type 2 diabetes?
    • Rosenson RS, Fioretto P, Dodson PM. Does microvascular disease predict macrovascular events in type 2 diabetes? Atherosclerosis 2011;218:13-18
    • (2011) Atherosclerosis , vol.218 , pp. 13-18
    • Rosenson, R.S.1    Fioretto, P.2    Dodson, P.M.3
  • 45
    • 33847231568 scopus 로고    scopus 로고
    • Coronary microvascular dysfunction
    • Camici PG, Crea F. Coronary microvascular dysfunction. N Engl J Med 2007;356:830-840
    • (2007) N Engl J Med , vol.356 , pp. 830-840
    • Camici, P.G.1    Crea, F.2
  • 46
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010;107:1058-1070
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 47
    • 80051545455 scopus 로고    scopus 로고
    • Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts
    • Burger D, Montezano AC, Nishigaki N, He Y, Carter A, Touyz RM. Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts. Arterioscler Thromb Vasc Biol 2011;31:1898-1907
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1898-1907
    • Burger, D.1    Montezano, A.C.2    Nishigaki, N.3    He, Y.4    Carter, A.5    Touyz, R.M.6
  • 48
    • 78651589386 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway
    • Xiao YF, Nikolskaya A, Jaye DA, Sigg DC. Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway. Cardiovasc Diabetol 2011;10:6
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 6
    • Xiao, Y.F.1    Nikolskaya, A.2    Jaye, D.A.3    Sigg, D.C.4
  • 49
    • 77953959949 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A
    • Oeseburg H, de Boer RA, Buikema H, van der Harst P, van Gilst WH, Silljé HH. Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. Arterioscler Thromb Vasc Biol 2010;30:1407-1414
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1407-1414
    • Oeseburg, H.1    De Boer, R.A.2    Buikema, H.3    Van Der Harst, P.4    Van Gilst, W.H.5    Silljé, H.H.6
  • 50
    • 84155163268 scopus 로고    scopus 로고
    • Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ ROCK-dependent manner
    • Brown JA, Diggs-Andrews KA, Gianino SM, Gutmann DH. Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ ROCK-dependent manner. Mol Cell Neurosci 2012;49:13-22
    • (2012) Mol Cell Neurosci , vol.49 , pp. 13-22
    • Brown, J.A.1    Diggs-Andrews, K.A.2    Gianino, S.M.3    Gutmann, D.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.