The Impact of Low-Dose Insulin on Peripheral Nerve Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Sugimoto, Kazuhiro ^a,b   Baba, Masayuki ^c   Suzuki, Susumu ^b   Yagihashi, Soroku ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b OHTA NISHINOUCHI HOSPITAL   (Japan)

^c AOMORI PREFECTURAL CENTRAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C; INSULIN; INSULIN RECEPTOR; LINPLANT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLACEBO; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFICACY; DRUG IMPLANT; DRUG RECEPTOR BINDING; EXPERIMENTAL RAT; HEMOGLOBIN BLOOD LEVEL; HYPERALGESIA; HYPOALGESIA; LOW DRUG DOSE; MALE; MOTOR NERVE CONDUCTION; NEUROPROTECTION; NONHUMAN; PERIPHERAL NERVE; PERIPHERAL NEUROPATHY; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; SCIATIC NERVE; SENSORY DYSFUNCTION; SENSORY NERVE CONDUCTION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; TEMPERATURE SENSITIVITY; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT ANTIBODY TECHNIQUE; GANGLIA, SPINAL; INSULIN; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYELIN SHEATH; NEURAL CONDUCTION; NOCICEPTION; PHOSPHORYLATION; RATS; RATS, WISTAR; RECEPTOR, INSULIN; SCIATIC NERVE; SIGNAL TRANSDUCTION;

EID: 84883345984     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074247     Document Type: Article

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