IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis

Journal of Clinical Investigation

Volumn 125, Issue 8, 2015, Pages 3269-3279

  Tohmonda, Takahide ^a,b   Yoda, Masaki ^a   Iwawaki, Takao ^c   Matsumoto, Morio ^a   Nakamura, Masaya ^a   Mikoshiba, Katsuhiko ^b   Toyama, Yoshiaki ^a   Horiuchi, Keisuke ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL REQUIRING PROTEIN 1ALPHA; PROTEIN IRE1; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; ERN1 PROTEIN, MOUSE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; ITPR3 PROTEIN, MOUSE; NFATC1 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RIBONUCLEASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ARTICLE; BONE MASS; CONTROLLED STUDY; IN VITRO STUDY; MALE; MOUSE; MULTINUCLEAR CELL; NONHUMAN; OSTEOCLAST; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY MECHANISM; UNFOLDED PROTEIN RESPONSE; ANIMAL; BONE MARROW CELL; CALCIUM SIGNALING; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BONE MARROW CELLS; CALCIUM SIGNALING; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; ENDORIBONUCLEASES; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MICE; MICE, KNOCKOUT; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE;

EID: 84939250408     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI76765     Document Type: Article

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