The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix

EMBO Reports

Volumn 12, Issue 5, 2011, Pages 451-457

  Tohmonda, Takahide ^a   Miyauchi, Yoshiteru ^a   Ghosh, Rajarshi ^b   Yoda, Masaki ^a   Uchikawa, Shinichi ^a   Takito, Jiro ^a   Morioka, Hideo ^a   Nakamura, Masaya ^a   Iwawaki, Takao ^c,d   Chiba, Kazuhiro ^a   Toyama, Yoshiaki ^a   Urano, Fumihiko ^b   Horiuchi, Keisuke ^a  

^a KEIO UNIVERSITY   (Japan)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c RIKEN   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

IRE1 ; osteoblast differentiation; Osterix; unfolded protein response; XBP1

Indexed keywords

BETA ACTIN; BINDING PROTEIN; BONE MORPHOGENETIC PROTEIN 2; PROTEIN IRE1ALPHA; SCLEROPROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ARTICLE; BINDING SITE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; OSTEOBLAST; OSTERIX GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; PROTEIN SECRETION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; GENE EXPRESSION REGULATION; HUMANS; LUCIFERASES; MICE; MICE, KNOCKOUT; OSTEOBLASTS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 79955536632     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2011.34     Document Type: Article

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