Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 2, 2007, Pages 491-494

  Hanessian, Stephen ^a   Charron, Guillaume ^a   Billich, Andreas ^b   Guerini, Danilo ^c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Novartis Institutes for Biomedical Research   (Austria)

Author keywords

Azacycle; Immunomodulation; Kinase; Sphingosine

Indexed keywords

FINGOLIMOD; IMMUNOMODULATING AGENT; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; FEMALE; MOLECULAR PROBE; NONHUMAN; RECEPTOR BINDING;

ANIMALS; AZA COMPOUNDS; CALCIUM; CELL LINE; CHO CELLS; CHROMATOGRAPHY, THIN LAYER; CRICETINAE; CRICETULUS; CYTOPLASM; DRUG DESIGN; HUMANS; IMMUNOLOGIC FACTORS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR PROBES; PHOSPHORYLATION; PROPYLENE GLYCOLS; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE;

EID: 33846215953     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.10.014     Document Type: Article

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