Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes

Journal of Pharmacology and Experimental Therapeutics

Volumn 309, Issue 2, 2004, Pages 758-768

  Forrest, M ^a   Sun, S Y ^a   Hajdu, R ^a   Bergstrom, J ^a   Card, D ^a   Doherty, G ^a,c   Hale, J ^a   Keohane, C ^a   Meyers, C ^a   Milligan, J ^a   Mills, S ^a   Nomura, N ^a   Rosen, H ^a,d   Rosenbach, M ^a   Shei, G J ^a   Singer, I I ^a   Tian, M ^a   West, S ^a   White, V ^a   Xie, J ^a   Proia, R L ^b   Mandala, S ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c ARRAY BIOPHARMA INC   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; FINGOLIMOD; G PROTEIN COUPLED RECEPTOR; LIPID; PHOSPHONIC ACID DERIVATIVE; RECEPTOR SUBTYPE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; SPHINGOSINE 1 PHOSPHATE RECEPTOR 4; SPHINGOSINE 1 PHOSPHATE RECEPTOR 5; SPHINGOSINE 1 PHOSPHATE RECEPTOR AGONIST; SPHINGOSINE DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRADYCARDIA; CARDIOVASCULAR EFFECT; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; GENE EXPRESSION; HYPERTENSION; IC 50; IMMUNOCOMPETENT CELL; IMMUNOLOCALIZATION; LIGAND BINDING; LYMPHOCYTE; LYMPHOCYTOPENIA; LYMPHOID ORGAN; MALE; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER; VASCULAR ENDOTHELIUM;

ANESTHESIA; ANIMALS; CHO CELLS; CRICETINAE; HUMANS; LYSOPHOSPHOLIPIDS; MALE; MICE; MYOCARDIUM; PROPYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; SPHINGOSINE;

EID: 11144355672     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.062828     Document Type: Article

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