메뉴 건너뛰기




Volumn 77, Issue 1, 2009, Pages 39-45

Regulation of vascular permeability by sphingosine 1-phosphate

Author keywords

Actin cytoskeleton; Adherens junction; Focal adhesion; G protein coupled receptor (GPCR); Rac GTPase; Sphingosine 1 phosphate (S1P); Sphingosine 1 phosphate receptor 1 (S1P1); Tight junction; Vascular permeability

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANOSINE TRIPHOSPHATASE; RHO KINASE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

EID: 59849085488     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2008.09.005     Document Type: Review
Times cited : (147)

References (71)
  • 1
    • 0032834765 scopus 로고    scopus 로고
    • Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions
    • Andriopoulou P., et al. Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 2286-2297
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 2286-2297
    • Andriopoulou, P.1
  • 2
    • 0030856846 scopus 로고    scopus 로고
    • Bradykinin- and thrombin-induced increases in endothelial permeability occur independently of phospholipase C but require protein kinase C activation
    • Aschner J.L., et al. Bradykinin- and thrombin-induced increases in endothelial permeability occur independently of phospholipase C but require protein kinase C activation. J. Cell Physiol. 173 (1997) 387-396
    • (1997) J. Cell Physiol. , vol.173 , pp. 387-396
    • Aschner, J.L.1
  • 3
    • 3042590902 scopus 로고    scopus 로고
    • Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis
    • Bazzoni G., and Dejana E. Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol. Rev. 84 (2004) 869-901
    • (2004) Physiol. Rev. , vol.84 , pp. 869-901
    • Bazzoni, G.1    Dejana, E.2
  • 4
    • 0030479470 scopus 로고    scopus 로고
    • Proteoglycan deposition in pulmonary fibrosis
    • Bensadoun E.S., et al. Proteoglycan deposition in pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 154 (1996) 1819-1828
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 1819-1828
    • Bensadoun, E.S.1
  • 5
    • 39149094614 scopus 로고    scopus 로고
    • Asymmetric focal adhesion disassembly in motile cells
    • Broussard J.A., et al. Asymmetric focal adhesion disassembly in motile cells. Curr. Opin. Cell Biol. 20 (2008) 85-90
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 85-90
    • Broussard, J.A.1
  • 6
    • 33750736991 scopus 로고    scopus 로고
    • FTY720 (fingolimod) in renal transplantation
    • Budde K., et al. FTY720 (fingolimod) in renal transplantation. Clin. Transplant. 17 20 Suppl (2006) 17-24
    • (2006) Clin. Transplant. , vol.17 , Issue.20 SUPPL , pp. 17-24
    • Budde, K.1
  • 7
    • 1642452871 scopus 로고    scopus 로고
    • Can exogenously administered hyaluronan improve respiratory function in patients with pulmonary emphysema?
    • Cantor J.O., and Turino G.M. Can exogenously administered hyaluronan improve respiratory function in patients with pulmonary emphysema?. Chest 125 (2004) 288-292
    • (2004) Chest , vol.125 , pp. 288-292
    • Cantor, J.O.1    Turino, G.M.2
  • 8
    • 0033597718 scopus 로고    scopus 로고
    • Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
    • Carmeliet P., et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 98 (1999) 147-157
    • (1999) Cell , vol.98 , pp. 147-157
    • Carmeliet, P.1
  • 9
    • 13044264471 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo
    • Corada M., et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 9815-9820
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 9815-9820
    • Corada, M.1
  • 10
    • 0034807581 scopus 로고    scopus 로고
    • Cytoskeletal regulation of pulmonary vascular permeability
    • Dudek S.M., and Garcia J.G. Cytoskeletal regulation of pulmonary vascular permeability. J. Appl. Physiol. 91 (2001) 1487-1500
    • (2001) J. Appl. Physiol. , vol.91 , pp. 1487-1500
    • Dudek, S.M.1    Garcia, J.G.2
  • 11
    • 2642580994 scopus 로고    scopus 로고
    • Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase
    • Dudek S.M., et al. Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. J. Biol. Chem. 279 (2004) 24692-24700
    • (2004) J. Biol. Chem. , vol.279 , pp. 24692-24700
    • Dudek, S.M.1
  • 12
    • 34250616679 scopus 로고    scopus 로고
    • Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P1 receptor
    • Dudek S.M., et al. Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P1 receptor. Cell Signal 19 (2007) 1754-1764
    • (2007) Cell Signal , vol.19 , pp. 1754-1764
    • Dudek, S.M.1
  • 13
    • 0034623082 scopus 로고    scopus 로고
    • Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1
    • Ebnet K., et al. Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. J. Biol. Chem. 275 (2000) 27979-27988
    • (2000) J. Biol. Chem. , vol.275 , pp. 27979-27988
    • Ebnet, K.1
  • 14
    • 20444443508 scopus 로고    scopus 로고
    • Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation
    • Finigan J.H., et al. Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation. J. Biol. Chem. 280 (2005) 17286-17293
    • (2005) J. Biol. Chem. , vol.280 , pp. 17286-17293
    • Finigan, J.H.1
  • 15
    • 0028110309 scopus 로고
    • Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
    • Furuse M., et al. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol. 127 (1994) 1617-1626
    • (1994) J. Cell Biol. , vol.127 , pp. 1617-1626
    • Furuse, M.1
  • 16
    • 0033571047 scopus 로고    scopus 로고
    • Manner of interaction of heterogeneous claudin species within and between tight junction strands
    • Furuse M., et al. Manner of interaction of heterogeneous claudin species within and between tight junction strands. J. Cell Biol. 147 (1999) 891-903
    • (1999) J. Cell Biol. , vol.147 , pp. 891-903
    • Furuse, M.1
  • 17
    • 0033060019 scopus 로고    scopus 로고
    • Regulation of endothelial cell myosin light chain kinase by Rho, cortactin, and p60(src)
    • Garcia J.G., et al. Regulation of endothelial cell myosin light chain kinase by Rho, cortactin, and p60(src). Am. J. Physiol. 276 (1999) L989-L998
    • (1999) Am. J. Physiol. , vol.276
    • Garcia, J.G.1
  • 18
    • 0034799675 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
    • Garcia J.G., et al. Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J. Clin. Invest. 108 (2001) 689-701
    • (2001) J. Clin. Invest. , vol.108 , pp. 689-701
    • Garcia, J.G.1
  • 19
    • 0014664384 scopus 로고
    • Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium
    • Gimbrone Jr. M.A., et al. Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium. Nature 222 (1969) 33-36
    • (1969) Nature , vol.222 , pp. 33-36
    • Gimbrone Jr., M.A.1
  • 20
    • 0346096592 scopus 로고    scopus 로고
    • Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype
    • Gosens R., et al. Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype. Eur. J. Pharmacol. 483 (2004) 71-78
    • (2004) Eur. J. Pharmacol. , vol.483 , pp. 71-78
    • Gosens, R.1
  • 21
    • 34247338134 scopus 로고    scopus 로고
    • Quantitative proteomics analysis of human endothelial cell membrane rafts: evidence of MARCKS and MRP regulation in the sphingosine 1-phosphate-induced barrier enhancement
    • Guo Y., et al. Quantitative proteomics analysis of human endothelial cell membrane rafts: evidence of MARCKS and MRP regulation in the sphingosine 1-phosphate-induced barrier enhancement. Mol. Cell Proteomics. 6 (2007) 689-696
    • (2007) Mol. Cell Proteomics. , vol.6 , pp. 689-696
    • Guo, Y.1
  • 22
    • 33845291120 scopus 로고    scopus 로고
    • Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases
    • Hait N.C. Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases. Biochim. Biophys. Acta. 1758 (2006) 2016-2026
    • (2006) Biochim. Biophys. Acta. , vol.1758 , pp. 2016-2026
    • Hait, N.C.1
  • 23
    • 0031836159 scopus 로고    scopus 로고
    • VEGF induces hyperpermeability by a direct action on endothelial cells
    • Hippenstiel S., et al. VEGF induces hyperpermeability by a direct action on endothelial cells. Am. J. Physiol. 274 (1998) L678-L684
    • (1998) Am. J. Physiol. , vol.274
    • Hippenstiel, S.1
  • 24
    • 0025311299 scopus 로고
    • An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors
    • Hla T., and Maciag T. An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. J. Biol. Chem. 265 (1990) 9308-9313
    • (1990) J. Biol. Chem. , vol.265 , pp. 9308-9313
    • Hla, T.1    Maciag, T.2
  • 25
    • 0035976579 scopus 로고    scopus 로고
    • Lysophospholipids-receptor revelations
    • Hla T., et al. Lysophospholipids-receptor revelations. Science 294 (2001) 1875-1878
    • (2001) Science , vol.294 , pp. 1875-1878
    • Hla, T.1
  • 26
    • 34247560661 scopus 로고    scopus 로고
    • Novel therapies for microvascular permeability in sepsis
    • Jacobson J.R., and Garcia J.G. Novel therapies for microvascular permeability in sepsis. Curr. Drug Targets 8 (2007) 509-514
    • (2007) Curr. Drug Targets , vol.8 , pp. 509-514
    • Jacobson, J.R.1    Garcia, J.G.2
  • 27
    • 77955799815 scopus 로고    scopus 로고
    • Oral fingolimod (FTY720) for relapsing multiple sclerosis
    • Kappos L., et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N. Engl. J. Med. 355 (2006) 1124-1140
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1124-1140
    • Kappos, L.1
  • 28
    • 0035913232 scopus 로고    scopus 로고
    • Recombinant human activated protein C for severe sepsis
    • (author reply 220-1)
    • Kapur S., et al. Recombinant human activated protein C for severe sepsis. N. Engl. J. Med. 345 (2001) 219-220 (author reply 220-1)
    • (2001) N. Engl. J. Med. , vol.345 , pp. 219-220
    • Kapur, S.1
  • 29
    • 38449083544 scopus 로고    scopus 로고
    • Dual regulation of endothelial junctional permeability
    • Komarova Y.A., et al. Dual regulation of endothelial junctional permeability. Sci. STKE 2007 (2007) re8
    • (2007) Sci. STKE , vol.2007
    • Komarova, Y.A.1
  • 30
    • 20044368257 scopus 로고    scopus 로고
    • Stable knock-down of the sphingosine 1-phosphate receptor S1P1 influences multiple functions of human endothelial cells
    • Krump-Konvalinkova V., et al. Stable knock-down of the sphingosine 1-phosphate receptor S1P1 influences multiple functions of human endothelial cells. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 546-552
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 546-552
    • Krump-Konvalinkova, V.1
  • 31
    • 33749350938 scopus 로고    scopus 로고
    • Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity
    • Lee J.F., et al. Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. J. Biol. Chem. 281 (2006) 29190-29200
    • (2006) J. Biol. Chem. , vol.281 , pp. 29190-29200
    • Lee, J.F.1
  • 32
    • 0029977136 scopus 로고    scopus 로고
    • The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway
    • Lee M.J., et al. The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway. J. Biol. Chem. 271 (1996) 11272-11279
    • (1996) J. Biol. Chem. , vol.271 , pp. 11272-11279
    • Lee, M.J.1
  • 33
    • 0032489574 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
    • Lee M.J., et al. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279 (1998) 1552-1555
    • (1998) Science , vol.279 , pp. 1552-1555
    • Lee, M.J.1
  • 34
    • 0033615537 scopus 로고    scopus 로고
    • Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
    • Lee M.J., et al. Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell 99 (1999) 301-312
    • (1999) Cell , vol.99 , pp. 301-312
    • Lee, M.J.1
  • 35
    • 16644394172 scopus 로고    scopus 로고
    • Endothelial cell barrier regulation by sphingosine 1-phosphate
    • McVerry B.J., and Garcia J.G. Endothelial cell barrier regulation by sphingosine 1-phosphate. J. Cell Biochem. 92 (2004) 1075-1085
    • (2004) J. Cell Biochem. , vol.92 , pp. 1075-1085
    • McVerry, B.J.1    Garcia, J.G.2
  • 36
    • 7044241285 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury
    • McVerry B.J., et al. Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am. J. Respir. Crit. Care Med. 170 (2004) 987-993
    • (2004) Am. J. Respir. Crit. Care Med. , vol.170 , pp. 987-993
    • McVerry, B.J.1
  • 37
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D., and Malik A.B. Signaling mechanisms regulating endothelial permeability. Physiol. Rev. 86 (2006) 279-367
    • (2006) Physiol. Rev. , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 38
    • 0037088851 scopus 로고    scopus 로고
    • Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function
    • Mehta D., et al. Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. J. Physiol. 539 (2002) 779-789
    • (2002) J. Physiol. , vol.539 , pp. 779-789
    • Mehta, D.1
  • 39
    • 20444431854 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells
    • Mehta D., et al. Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. J. Biol. Chem. 280 (2005) 17320-17328
    • (2005) J. Biol. Chem. , vol.280 , pp. 17320-17328
    • Mehta, D.1
  • 40
    • 0032772422 scopus 로고    scopus 로고
    • Microvascular permeability
    • Michel C.C., and Curry F.E. Microvascular permeability. Physiol. Rev. 79 (1999) 703-761
    • (1999) Physiol. Rev. , vol.79 , pp. 703-761
    • Michel, C.C.1    Curry, F.E.2
  • 41
    • 0023605609 scopus 로고
    • Transcytosis of albumin in capillary endothelium
    • Milici A.J., et al. Transcytosis of albumin in capillary endothelium. J. Cell Biol. 105 (1987) 2603-2612
    • (1987) J. Cell Biol. , vol.105 , pp. 2603-2612
    • Milici, A.J.1
  • 42
    • 0037648580 scopus 로고    scopus 로고
    • Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
    • Nitta T., et al. Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J. Cell Biol. 161 (2003) 653-660
    • (2003) J. Cell Biol. , vol.161 , pp. 653-660
    • Nitta, T.1
  • 43
    • 2542461296 scopus 로고    scopus 로고
    • Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury
    • Peng X., et al. Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. Am. J. Respir. Crit. Care Med. 169 (2004) 1245-1251
    • (2004) Am. J. Respir. Crit. Care Med. , vol.169 , pp. 1245-1251
    • Peng, X.1
  • 44
    • 33947147730 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate signaling in the cardiovascular system
    • Peters S.L., and Alewijnse A.E. Sphingosine-1-phosphate signaling in the cardiovascular system. Curr. Opin. Pharmacol. 7 (2007) 186-192
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 186-192
    • Peters, S.L.1    Alewijnse, A.E.2
  • 45
    • 35348872064 scopus 로고    scopus 로고
    • Molecular determinants of endothelial transcytosis and their role in endothelial permeability
    • Predescu S.A., et al. Molecular determinants of endothelial transcytosis and their role in endothelial permeability. Am. J. Physiol. Lung Cell Mol. Physiol. 293 (2007) L823-L842
    • (2007) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.293
    • Predescu, S.A.1
  • 46
    • 0031730518 scopus 로고    scopus 로고
    • A computed tomography scan assessment of regional lung volume in acute lung injury. The CT Scan ARDS Study Group
    • Puybasset L., et al. A computed tomography scan assessment of regional lung volume in acute lung injury. The CT Scan ARDS Study Group. Am. J. Respir. Crit. Care Med. 158 (1998) 1644-1655
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , pp. 1644-1655
    • Puybasset, L.1
  • 47
    • 0037968715 scopus 로고    scopus 로고
    • Endothelial barrier strengthening by activation of focal adhesion kinase
    • Quadri S.K., et al. Endothelial barrier strengthening by activation of focal adhesion kinase. J. Biol. Chem. 278 (2003) 13342-13349
    • (2003) J. Biol. Chem. , vol.278 , pp. 13342-13349
    • Quadri, S.K.1
  • 48
    • 21844457949 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network
    • Rosen H., and Goetzl E.J. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat. Rev. Immunol. 5 (2005) 560-570
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 560-570
    • Rosen, H.1    Goetzl, E.J.2
  • 49
    • 0036088112 scopus 로고    scopus 로고
    • TNF-alpha disruption of lung endothelial integrity: reduced integrin mediated adhesion to fibronectin
    • Rotundo R.F., et al. TNF-alpha disruption of lung endothelial integrity: reduced integrin mediated adhesion to fibronectin. Am. J. Physiol. Lung Cell Mol. Physiol. 282 (2002) L316-L329
    • (2002) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.282
    • Rotundo, R.F.1
  • 50
    • 0015259329 scopus 로고
    • Effects of platelet transfusions: plug formation and maintenance of vascular integrity
    • Roy A.J., and Djerassi I. Effects of platelet transfusions: plug formation and maintenance of vascular integrity. Proc. Soc. Exp. Biol. Med. 139 (1972) 137-142
    • (1972) Proc. Soc. Exp. Biol. Med. , vol.139 , pp. 137-142
    • Roy, A.J.1    Djerassi, I.2
  • 51
    • 0037636489 scopus 로고    scopus 로고
    • Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products
    • Schaphorst K.L., et al. Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. Am. J. Physiol. Lung Cell Mol. Physiol. 285 (2003) L258-L267
    • (2003) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.285
    • Schaphorst, K.L.1
  • 52
    • 0345529916 scopus 로고    scopus 로고
    • Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT
    • Shikata Y., et al. Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT. FASEB J. 17 (2003) 2240-2249
    • (2003) FASEB J. , vol.17 , pp. 2240-2249
    • Shikata, Y.1
  • 53
    • 0037370946 scopus 로고    scopus 로고
    • S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin
    • Shikata Y., et al. S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin. J. Appl. Physiol. 94 (2003) 1193-1203
    • (2003) J. Appl. Physiol. , vol.94 , pp. 1193-1203
    • Shikata, Y.1
  • 54
    • 26444551684 scopus 로고    scopus 로고
    • Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin
    • Singleton P.A., et al. Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin. FASEB J. 19 (2005) 1646-1656
    • (2005) FASEB J. , vol.19 , pp. 1646-1656
    • Singleton, P.A.1
  • 55
    • 33845949505 scopus 로고    scopus 로고
    • Transactivation of sphingosine 1-phosphate receptors is essential for vascular barrier regulation. Novel role for hyaluronan and CD44 receptor family
    • Singleton P.A., et al. Transactivation of sphingosine 1-phosphate receptors is essential for vascular barrier regulation. Novel role for hyaluronan and CD44 receptor family. J. Biol. Chem. 281 (2006) 34381-34393
    • (2006) J. Biol. Chem. , vol.281 , pp. 34381-34393
    • Singleton, P.A.1
  • 56
    • 34547915639 scopus 로고    scopus 로고
    • Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation
    • Singleton P.A., et al. Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation. Am. J. Respir. Cell Mol. Biol. 37 (2007) 222-231
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.37 , pp. 222-231
    • Singleton, P.A.1
  • 57
    • 33845708225 scopus 로고    scopus 로고
    • Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space
    • Tani M. Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space. Cell Signal 19 (2007) 229-237
    • (2007) Cell Signal , vol.19 , pp. 229-237
    • Tani, M.1
  • 58
    • 47749089703 scopus 로고    scopus 로고
    • Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin
    • Teran Arce F., et al. Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. Biophys. J. 95 2 (2008) 886-894
    • (2008) Biophys. J. , vol.95 , Issue.2 , pp. 886-894
    • Teran Arce, F.1
  • 59
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: from extracellular glue to pericellular cue
    • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer 4 (2004) 528-539
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 60
    • 33644866797 scopus 로고    scopus 로고
    • Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response
    • Tzima E. Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response. Circ. Res. 98 (2006) 176-185
    • (2006) Circ. Res. , vol.98 , pp. 176-185
    • Tzima, E.1
  • 61
    • 2342482455 scopus 로고    scopus 로고
    • GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions
    • van Nieuw Amerongen G.P., et al. GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions. Circ. Res. 94 (2004) 1041-1049
    • (2004) Circ. Res. , vol.94 , pp. 1041-1049
    • van Nieuw Amerongen, G.P.1
  • 62
    • 33746897677 scopus 로고    scopus 로고
    • Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient
    • Venkataraman K., et al. Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient. Biochem. J. 397 (2006) 461-471
    • (2006) Biochem. J. , vol.397 , pp. 461-471
    • Venkataraman, K.1
  • 63
    • 0036720803 scopus 로고    scopus 로고
    • Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and beta-catenin
    • Venkiteswaran K. Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and beta-catenin. Am. J. Physiol. Cell Physiol. 283 (2002) C811-C821
    • (2002) Am. J. Physiol. Cell Physiol. , vol.283
    • Venkiteswaran, K.1
  • 64
    • 38549128935 scopus 로고    scopus 로고
    • VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
    • Vestweber D. VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler. Thromb. Vasc. Biol. 28 (2008) 223-232
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 223-232
    • Vestweber, D.1
  • 65
    • 0037096160 scopus 로고    scopus 로고
    • Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells
    • Vouret-Craviari V., et al. Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells. J. Cell Sci. 115 (2002) 2475-2484
    • (2002) J. Cell Sci. , vol.115 , pp. 2475-2484
    • Vouret-Craviari, V.1
  • 66
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • Ware L.B., and Matthay M.A. The acute respiratory distress syndrome. N. Engl. J. Med. 342 (2000) 1334-1349
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 67
    • 33644863157 scopus 로고    scopus 로고
    • Activation of Rac-1 and Cdc42 stabilizes the microvascular endothelial barrier
    • Waschke J., et al. Activation of Rac-1 and Cdc42 stabilizes the microvascular endothelial barrier. Histochem. Cell Biol. 125 (2006) 397-406
    • (2006) Histochem. Cell Biol. , vol.125 , pp. 397-406
    • Waschke, J.1
  • 68
    • 33744783930 scopus 로고    scopus 로고
    • Rac1 and RhoA as regulators of endothelial phenotype and barrier function in hypoxia-induced neonatal pulmonary hypertension
    • Wojciak-Stothard B., et al. Rac1 and RhoA as regulators of endothelial phenotype and barrier function in hypoxia-induced neonatal pulmonary hypertension. Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2006) L1173-L1182
    • (2006) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.290
    • Wojciak-Stothard, B.1
  • 69
    • 35048835160 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase
    • Xu M., et al. Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. Am. J. Physiol. Cell Physiol. 293 (2007) C1309-C1318
    • (2007) Am. J. Physiol. Cell Physiol. , vol.293
    • Xu, M.1
  • 70
    • 0032734494 scopus 로고    scopus 로고
    • Metabolism and functional effects of sphingolipids in blood cells
    • Yang L., et al. Metabolism and functional effects of sphingolipids in blood cells. Br. J. Haematol. 107 (1999) 282-293
    • (1999) Br. J. Haematol. , vol.107 , pp. 282-293
    • Yang, L.1
  • 71
    • 0029052921 scopus 로고
    • Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets
    • Yatomi Y., et al. Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets. Blood 86 (1995) 193-202
    • (1995) Blood , vol.86 , pp. 193-202
    • Yatomi, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.