Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 20, 2005, Pages 4470-4474

  Foss Jr , Frank W ^a   Clemens, Jeremy J ^a   Davis, Michael D ^a   Snyder, Ashley H ^b   Zigler, Molly A ^a   Lynch, Kevin R ^a,b   Macdonald, Timothy L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Lymphopenia; Phosphothioate; Sphingosine 1 phosphate

Indexed keywords

ALCOHOL DERIVATIVE; FINGOLIMOD; G PROTEIN COUPLED RECEPTOR; IMMUNOMODULATING AGENT; LIGAND; PHOSPHATE; PHOSPHOROTHIOIC ACID DERIVATIVE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

ALCOHOL BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; IN VIVO STUDY; LYMPHOCYTOPENIA; METABOLIC REGULATION; MOUSE; NONHUMAN; PHOSPHATE BLOOD LEVEL; PRECURSOR;

MAGNETIC RESONANCE SPECTROSCOPY; RECEPTORS, LYSOSPHINGOLIPID; THIONUCLEOTIDES;

EID: 24344465322     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.057     Document Type: Article

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