Age-related changes in mRNA levels of hepatic transporters, cytochrome P450 and UDP-glucuronosyltransferase in female rats

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 40, Issue 2, 2015, Pages 239-244

  Kawase, Atsushi ^a   Ito, Ayami ^a   Yamada, Ayano ^a   Iwaki, Masahiro ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

Aging; Cytochrome P450; Liver; Transporter

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CYTOCHROME P450; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1A1; ABC TRANSPORTER; ABCG2 PROTEIN, RAT; CARRIER PROTEIN; CYP3A1 PROTEIN, RAT; CYP3A2 PROTEIN, RAT; CYTOCHROME P450 3A; ORGANIC ANION TRANSPORTER; SLC21A1 PROTEIN, RAT; UGT1A1 PROTEIN, RAT;

AGE DISTRIBUTION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE; FEMALE; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RAT MODEL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SEX DIFFERENCE; ANIMAL; GENETICS; LIVER; METABOLISM; WISTAR RAT;

AGING; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CYTOCHROME P-450 CYP3A; FEMALE; GLUCURONOSYLTRANSFERASE; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 84938747867     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-014-0208-7     Document Type: Article

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