Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

Archives of Toxicology

Volumn 84, Issue 12, 2010, Pages 939-946

  Yun, Kang UK ^a   Oh, Soo Jin ^a,b   Oh, Jung Min ^a   Kang, Keon Wook ^c   Myung, Chang Seon ^a   Song, Gyu Yong ^a   Kim, Bong Hee ^a   Kim, Sang Kyum ^a  

^a Chungnam National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Cytochrome P450; Development and aging; Drug metabolizing enzyme; Expression and activity; Liver

Indexed keywords

4 NITROPHENOL HYDROXYLASE; CYTOCHROME B5; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2C11; CYTOCHROME P450 2E1; CYTOCHROME P450 3A2; ETHOXYRESORUFIN DEETHYLASE; METHOXYRESORUFIN O DEMETHYLASE; MIDAZOLAM; O DEMETHYLASE; OXYGENASE; PENTOXYRESORUFIN DEALKYLASE; UNCLASSIFIED DRUG; CYP2C11 PROTEIN, RAT; CYP3A2 PROTEIN, RAT; ISOENZYME; MEMBRANE PROTEIN; STEROID 16ALPHA MONOOXYGENASE; UNSPECIFIC MONOOXYGENASE;

AGE DISTRIBUTION; AGING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; LIVER; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBERTY; RAT; WEANING; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

AGING; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; ISOENZYMES; LIVER; MALE; MEMBRANE PROTEINS; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; STEROID 16-ALPHA-HYDROXYLASE;

EID: 79952806715     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-010-0520-1     Document Type: Article

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