SAβPPα is a Potent Endogenous Inhibitor of BACE1

Journal of Alzheimer's Disease

Volumn 47, Issue 3, 2015, Pages 545-555

  Peters Libeu, Clare ^a   Campagna, Jesus ^b   Mitsumori, Michael ^a   Poksay, Karen S ^a   Spilman, Patricia ^b   Sabogal, Alex ^a   Bredesen, Dale E ^a,b,c   John, Varghese ^a,b,c  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN ALPHA; AMYLOID PRECURSOR PROTEIN BETA; BETA SECRETASE 1; UNCLASSIFIED DRUG; ALPHA-SAPP PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN; SECRETASE;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; NERVE CELL PLASTICITY; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; IMMUNOPRECIPITATION; METABOLISM; PROTEIN CONFORMATION; SMALL ANGLE SCATTERING; SPECTROFLUOROMETRY; X RAY DIFFRACTION;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; HUMANS; IMMUNOPRECIPITATION; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SCATTERING, SMALL ANGLE; SPECTROMETRY, FLUORESCENCE; X-RAY DIFFRACTION;

EID: 84938691417     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150282     Document Type: Article

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