The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress

Journal of Alzheimer's Disease

Volumn 28, Issue 3, 2012, Pages 515-530

  Moussavi Nik, Seyyed Hani ^a   Wilson, Lachlan ^a   Newman, Morgan ^a   Croft, Kevin ^b   Mori, Trevor A ^b   Musgrave, Ian ^a   Lardelli, Michael ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Alzheimer's disease; amyloid protein precursor; BACE1; hypoxia; oxidative stress; presenilins; zebrafish; secretase

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ARACHIDONIC ACID; BETA SECRETASE 1; GAMMA SECRETASE; MESSENGER RNA; PROTEIN; PSEN PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; EMBRYO; ENZYME ACTIVITY; GENE ACTIVITY; GENE EXPRESSION; HYPOXIA; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UPREGULATION; ZEBRA FISH;

EID: 84858010178     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-110533     Document Type: Article

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