Detrimental effect of genetic inhibition of B-site app-cleaving enzyme 1 on functional outcome after controlled cortical impact in young adult mice

Journal of Neurotrauma

Volumn 28, Issue 9, 2011, Pages 1855-1861

  Mannix, Rebekah C ^a,b   Zhang, Jimmy ^b   Park, Juyeon ^b   Lee, Christopher ^b   Whalen, Michael J ^b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

amyloid; traumatic brain injury

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN PROTECTION; BRAIN SIZE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME ACTIVE SITE; EXPERIMENTAL MODEL; GENE DELETION; GENETIC ANALYSIS; HIPPOCAMPUS; HISTOPATHOLOGY; INJURY SEVERITY; MALE; MAZE TEST; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; SCORING SYSTEM; TRAUMATIC BRAIN INJURY; WILD TYPE;

AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN INJURIES; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE; MICE, KNOCKOUT; RECOVERY OF FUNCTION;

EID: 80054809609     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.1759     Document Type: Article

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