Predictive biomarkers in precision medicine and drug development against lung cancer

Chinese Journal of Cancer

Volumn 34, Issue 7, 2015, Pages

  Fang, Bingliang ^a   Mehran, Reza J ^a   Heymach, John V ^a   Swisher, Stephen G ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Anaplastic lymphoma kinase (ALK); Biomarkers; Drug development; Epidermal growth factor receptor (EGFR); Immunotherapy; Personalized therapy; Precision medicine

Indexed keywords

ALECTINIB; ANAPLASTIC LYMPHOMA KINASE; B RAF KINASE; BIOLOGICAL MARKER; BRCA1 PROTEIN; CERITINIB; CRIZOTINIB; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; E1A ASSOCIATED P300 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GEFITINIB; K RAS PROTEIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN; NOTCH2 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN KINASE LKB1; PROTEIN P53; PROTEIN TYROSINE KINASE; SULFOTRANSFERASE 1A1; TRANSCRIPTION FACTOR GATA 2; VEMURAFENIB; EGFR PROTEIN, HUMAN; ONCOPROTEIN; ROS1 PROTEIN, HUMAN; TUMOR MARKER;

ANTINEOPLASTIC ACTIVITY; CANCER IMMUNOTHERAPY; DRUG DESIGN; FLUORESCENCE IN SITU HYBRIDIZATION; FRAMESHIFT MUTATION; GENE EXPRESSION REGULATION; GENETIC HETEROGENEITY; HUMAN; LUNG ADENOCARCINOMA; LUNG CARCINOMA; MISSENSE MUTATION; MOLECULARLY TARGETED THERAPY; POLYMERASE CHAIN REACTION; PRECISION MEDICINE; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; SMALL CELL LUNG CANCER; SQUAMOUS CELL LUNG CARCINOMA; CELL TRANSFORMATION; DRUG RESISTANCE; LUNG TUMOR; PERSONALIZED MEDICINE; PHARMACOGENETICS; PROTO ONCOGENE;

BIOMARKERS, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DRUG RESISTANCE, NEOPLASM; GENES, ERBB-1; HUMANS; LUNG NEOPLASMS; PHARMACOGENETICS; PRECISION MEDICINE; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84938254587     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.1186/s40880-015-0028-4     Document Type: Review

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