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Volumn 22, Issue 19, 2014, Pages 5234-5240
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Prodrug oncrasin-266 improves the stability, pharmacokinetics, and safety of NSC-743380
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Author keywords
Cancer; Drug development; Prodrug; Synthetic lethality
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Indexed keywords
ACETIC ACID DERIVATIVE;
ANTIMITOTIC AGENT;
ANTINEOPLASTIC AGENT;
CYCLOHEXYLACETIC ACID;
ONCRASIN 266;
ONCRASIN 72;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
CANCER CELL CULTURE;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DISTRIBUTION;
DRUG ELIMINATION;
DRUG FORMULATION;
DRUG HALF LIFE;
DRUG POTENTIATION;
DRUG SAFETY;
DRUG STABILITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TOLERABILITY;
HUMAN;
HUMAN CELL;
HYDROLYSIS;
IN VITRO STUDY;
IN VIVO STUDY;
MOUSE;
NONHUMAN;
ONCOGENE K RAS;
PHYSICAL CHEMISTRY;
PROCESS DEVELOPMENT;
TISSUE DISTRIBUTION;
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EID: 84907506533
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2014.08.006 Document Type: Article |
Times cited : (8)
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References (18)
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