메뉴 건너뛰기




Volumn 72, Issue 11, 2015, Pages 2091-2106

An updated review of mechanotransduction in skin disorders: Transcriptional regulators, ion channels, and microRNAs

Author keywords

Fibrosis; Hypertrophic scar; Piezo; Scleroderma; TRP; Wound healing

Indexed keywords

BETA CATENIN; HIPPO PROTEIN, HUMAN; ION CHANNEL; MICRORNA; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAZ PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

EID: 84938059373     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-1853-y     Document Type: Review
Times cited : (56)

References (183)
  • 1
    • 79955441991 scopus 로고    scopus 로고
    • Balancing forces: Architectural control of mechanotransduction
    • 3564968 1:CAS:528:DC%2BC3MXltVOisrY%3D 21508987
    • DuFort CC, Paszek MJ, Weaver VM (2011) Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol 12:308-319
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 308-319
    • Dufort, C.C.1    Paszek, M.J.2    Weaver, V.M.3
  • 2
    • 84890546299 scopus 로고    scopus 로고
    • Mechanical stretch upregulates SDF-1alpha in skin tissue and induces migration of circulating bone marrow-derived stem cells into the expanded skin
    • 1:CAS:528:DC%2BC2cXjtVCmsbs%3D 23836581
    • Zhou SB, Wang J, Chiang CA, Sheng LL, Li QF (2013) Mechanical stretch upregulates SDF-1alpha in skin tissue and induces migration of circulating bone marrow-derived stem cells into the expanded skin. Stem Cells 31:2703-2713
    • (2013) Stem Cells , vol.31 , pp. 2703-2713
    • Zhou, S.B.1    Wang, J.2    Chiang, C.A.3    Sheng, L.L.4    Li, Q.F.5
  • 4
    • 84855555498 scopus 로고    scopus 로고
    • Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling
    • 1:CAS:528:DC%2BC3MXhs1Sitr3E
    • Wong VW, Rustad KC, Akaishi S, Sorkin M, Glotzbach JP, Januszyk M et al (2012) Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling. Nat Med 18:148-152
    • (2012) Nat Med , vol.18 , pp. 148-152
    • Wong, V.W.1    Rustad, K.C.2    Akaishi, S.3    Sorkin, M.4    Glotzbach, J.P.5    Januszyk, M.6
  • 5
    • 80054753943 scopus 로고    scopus 로고
    • Pushing back: Wound mechanotransduction in repair and regeneration
    • 1:CAS:528:DC%2BC3MXhtlWltbjJ 21776006
    • Wong VW, Akaishi S, Longaker MT, Gurtner GC (2011) Pushing back: wound mechanotransduction in repair and regeneration. J Invest Dermatol 131:2186-2196
    • (2011) J Invest Dermatol , vol.131 , pp. 2186-2196
    • Wong, V.W.1    Akaishi, S.2    Longaker, M.T.3    Gurtner, G.C.4
  • 7
    • 68549127162 scopus 로고    scopus 로고
    • Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer
    • 1:CAS:528:DC%2BD1MXos1eru74%3D 19022747
    • Watt FM, Collins CA (2008) Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer. Cold Spring Harb Symp Quant Biol 73:503-512
    • (2008) Cold Spring Harb Symp Quant Biol , vol.73 , pp. 503-512
    • Watt, F.M.1    Collins, C.A.2
  • 8
    • 84862171364 scopus 로고    scopus 로고
    • The many faces and functions of beta-catenin
    • 3380220 1:CAS:528:DC%2BC38XntlSktbY%3D 22617422
    • Valenta T, Hausmann G, Basler K (2012) The many faces and functions of beta-catenin. EMBO J 31:2714-2736
    • (2012) EMBO J , vol.31 , pp. 2714-2736
    • Valenta, T.1    Hausmann, G.2    Basler, K.3
  • 9
    • 84889242647 scopus 로고    scopus 로고
    • Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling
    • 4081860 1:CAS:528:DC%2BC3sXhvVKhtLvF 24311688
    • Lim X, Tan SH, Koh WL, Chau RM, Yan KS, Kuo CJ et al (2013) Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. Science 342:1226-1230
    • (2013) Science , vol.342 , pp. 1226-1230
    • Lim, X.1    Tan, S.H.2    Koh, W.L.3    Chau, R.M.4    Yan, K.S.5    Kuo, C.J.6
  • 10
    • 80052830219 scopus 로고    scopus 로고
    • A mechanism of mechanotransduction at the cell-cell interface: Emergence of alpha-catenin as the center of a force-balancing mechanism for morphogenesis in multicellular organisms
    • 1:CAS:528:DC%2BC3MXhtFGqu7bO
    • Yonemura S (2011) A mechanism of mechanotransduction at the cell-cell interface: emergence of alpha-catenin as the center of a force-balancing mechanism for morphogenesis in multicellular organisms. Bioessays News Rev Mol Cell Dev Biol 33:732-736
    • (2011) Bioessays News Rev Mol Cell Dev Biol , vol.33 , pp. 732-736
    • Yonemura, S.1
  • 11
    • 57649237947 scopus 로고    scopus 로고
    • Beta-catenin levels influence rapid mechanical responses in osteoblasts
    • 2570859 1:CAS:528:DC%2BD1cXht1Glsb3O 18723514
    • Case N, Ma M, Sen B, Xie Z, Gross TS, Rubin J (2008) Beta-catenin levels influence rapid mechanical responses in osteoblasts. J Biol Chem 283:29196-29205
    • (2008) J Biol Chem , vol.283 , pp. 29196-29205
    • Case, N.1    Ma, M.2    Sen, B.3    Xie, Z.4    Gross, T.S.5    Rubin, J.6
  • 12
    • 71749108831 scopus 로고    scopus 로고
    • Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node
    • 2787323 1:CAS:528:DC%2BD1MXhsFWitLbN 19840939
    • Sen B, Styner M, Xie Z, Case N, Rubin CT, Rubin J (2009) Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node. J Biol Chem 284:34607-34617
    • (2009) J Biol Chem , vol.284 , pp. 34607-34617
    • Sen, B.1    Styner, M.2    Xie, Z.3    Case, N.4    Rubin, C.T.5    Rubin, J.6
  • 13
    • 84867631207 scopus 로고    scopus 로고
    • Mechanical properties of beta-catenin revealed by single-molecule experiments
    • 3475332 1:CAS:528:DC%2BC38XhsFCks7vN 23083718
    • Valbuena A, Vera AM, Oroz J, Menendez M, Carrion-Vazquez M (2012) Mechanical properties of beta-catenin revealed by single-molecule experiments. Biophys J 103:1744-1752
    • (2012) Biophys J , vol.103 , pp. 1744-1752
    • Valbuena, A.1    Vera, A.M.2    Oroz, J.3    Menendez, M.4    Carrion-Vazquez, M.5
  • 14
    • 84880633970 scopus 로고    scopus 로고
    • Beta-Catenin protects the epidermis from mechanical stresses
    • 3704987 1:CAS:528:DC%2BC3sXhtFalur7M 23816618
    • Ray S, Foote HP, Lechler T (2013) beta-Catenin protects the epidermis from mechanical stresses. J Cell Biol 202:45-52
    • (2013) J Cell Biol , vol.202 , pp. 45-52
    • Ray, S.1    Foote, H.P.2    Lechler, T.3
  • 15
    • 79958735965 scopus 로고    scopus 로고
    • Actomyosin-mediated cellular tension drives increased tissue stiffness and beta-catenin activation to induce epidermal hyperplasia and tumor growth
    • 3115541 1:CAS:528:DC%2BC3MXnsVClu7Y%3D 21665151
    • Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P et al (2011) Actomyosin-mediated cellular tension drives increased tissue stiffness and beta-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell 19:776-791
    • (2011) Cancer Cell , vol.19 , pp. 776-791
    • Samuel, M.S.1    Lopez, J.I.2    McGhee, E.J.3    Croft, D.R.4    Strachan, D.5    Timpson, P.6
  • 16
    • 36549074631 scopus 로고    scopus 로고
    • YAP1 increases organ size and expands undifferentiated progenitor cells
    • 1:CAS:528:DC%2BD2sXhtlyrurzK 17980593
    • Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R et al (2007) YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 17:2054-2060
    • (2007) Curr Biol , vol.17 , pp. 2054-2060
    • Camargo, F.D.1    Gokhale, S.2    Johnnidis, J.B.3    Fu, D.4    Bell, G.W.5    Jaenisch, R.6
  • 17
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
    • 1:CAS:528:DC%2BD2MXovV2qs78%3D 16096061
    • Huang J, Wu S, Barrera J, Matthews K, Pan D (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122:421-434
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 18
    • 79960997489 scopus 로고    scopus 로고
    • The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
    • 3987945 1:CAS:528:DC%2BC3MXpsFKnsLc%3D 21808241
    • Zhao B, Tumaneng K, Guan KL (2011) The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat Cell Biol 13:877-883
    • (2011) Nat Cell Biol , vol.13 , pp. 877-883
    • Zhao, B.1    Tumaneng, K.2    Guan, K.L.3
  • 19
    • 78650895035 scopus 로고    scopus 로고
    • Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
    • 3012936 21205866
    • Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei QY et al (2011) Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Gene Dev 25:51-63
    • (2011) Gene Dev , vol.25 , pp. 51-63
    • Zhao, B.1    Li, L.2    Lu, Q.3    Wang, L.H.4    Liu, C.Y.5    Lei, Q.Y.6
  • 20
    • 79952298459 scopus 로고    scopus 로고
    • Yap1 acts downstream of alpha-catenin to control epidermal proliferation
    • 3237196 1:CAS:528:DC%2BC3MXjsFeqt7g%3D 21376238
    • Schlegelmilch K, Mohseni M, Kirak O, Pruszak J, Rodriguez JR, Zhou D et al (2011) Yap1 acts downstream of alpha-catenin to control epidermal proliferation. Cell 144:782-795
    • (2011) Cell , vol.144 , pp. 782-795
    • Schlegelmilch, K.1    Mohseni, M.2    Kirak, O.3    Pruszak, J.4    Rodriguez, J.R.5    Zhou, D.6
  • 21
    • 84865455267 scopus 로고    scopus 로고
    • Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP
    • 1:CAS:528:DC%2BC38XhtF2gurrO 22884261
    • Miller E, Yang J, DeRan M, Wu C, Su AI, Bonamy GM et al (2012) Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol 19:955-962
    • (2012) Chem Biol , vol.19 , pp. 955-962
    • Miller, E.1    Yang, J.2    Deran, M.3    Wu, C.4    Su, A.I.5    Bonamy, G.M.6
  • 22
    • 84865260845 scopus 로고    scopus 로고
    • Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
    • 3433174 1:CAS:528:DC%2BC38XhtFGku7rP 22863277
    • Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH et al (2012) Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 150:780-791
    • (2012) Cell , vol.150 , pp. 780-791
    • Yu, F.X.1    Zhao, B.2    Panupinthu, N.3    Jewell, J.L.4    Lian, I.5    Wang, L.H.6
  • 24
    • 84883466306 scopus 로고    scopus 로고
    • A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors
    • 1:CAS:528:DC%2BC3sXht1yhsrzI 23954413
    • Aragona M, Panciera T, Manfrin A, Giulitti S, Michielin F, Elvassore N et al (2013) A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell 154:1047-1059
    • (2013) Cell , vol.154 , pp. 1047-1059
    • Aragona, M.1    Panciera, T.2    Manfrin, A.3    Giulitti, S.4    Michielin, F.5    Elvassore, N.6
  • 25
    • 84901232687 scopus 로고    scopus 로고
    • Mechanical memory and dosing influence stem cell fate
    • 4031270 1:CAS:528:DC%2BC2cXktlGntbs%3D 24633344
    • Yang C, Tibbitt MW, Basta L, Anseth KS (2014) Mechanical memory and dosing influence stem cell fate. Nat Mater 13:645-652
    • (2014) Nat Mater , vol.13 , pp. 645-652
    • Yang, C.1    Tibbitt, M.W.2    Basta, L.3    Anseth, K.S.4
  • 26
    • 84878615570 scopus 로고    scopus 로고
    • Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
    • 1:CAS:528:DC%2BC3sXot1Cgsr0%3D 23708000
    • Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI et al (2013) Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol 15:637-646
    • (2013) Nat Cell Biol , vol.15 , pp. 637-646
    • Calvo, F.1    Ege, N.2    Grande-Garcia, A.3    Hooper, S.4    Jenkins, R.P.5    Chaudhry, S.I.6
  • 27
    • 84905101429 scopus 로고    scopus 로고
    • YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
    • 1:CAS:528:DC%2BC2cXntFCqurw%3D 24747426
    • Low BC, Pan CQ, Shivashankar GV, Bershadsky A, Sudol M, Sheetz M (2014) YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth. FEBS Lett 588:2663-2670
    • (2014) FEBS Lett , vol.588 , pp. 2663-2670
    • Low, B.C.1    Pan, C.Q.2    Shivashankar, G.V.3    Bershadsky, A.4    Sudol, M.5    Sheetz, M.6
  • 28
    • 84892818938 scopus 로고    scopus 로고
    • Ran Byun M, Furutani-Seiki M, Hong JH, Jung HS. YAP and TAZ regulate skin wound healing
    • 1:CAS:528:DC%2BC3sXhsFymsrvM 24108406
    • Lee MJ (2014) Ran Byun M, Furutani-Seiki M, Hong JH, Jung HS. YAP and TAZ regulate skin wound healing. J Invest Dermatol 134:518-525
    • (2014) J Invest Dermatol , vol.134 , pp. 518-525
    • Lee, M.J.1
  • 29
    • 84878600591 scopus 로고    scopus 로고
    • Yap Controls Stem/Progenitor Cell Proliferation in the Mouse Postnatal Epidermis
    • 23190885
    • Beverdam A, Claxton C, Zhang X, James G, Harvey KF, Key B (2012) Yap Controls Stem/Progenitor Cell Proliferation in the Mouse Postnatal Epidermis. J Invest Dermatol 133:1497-1505
    • (2012) J Invest Dermatol , vol.133 , pp. 1497-1505
    • Beverdam, A.1    Claxton, C.2    Zhang, X.3    James, G.4    Harvey, K.F.5    Key, B.6
  • 30
    • 79952297528 scopus 로고    scopus 로고
    • Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
    • 3038759 1:CAS:528:DC%2BC3MXitFKqtLY%3D 21262812
    • Zhang H, Pasolli HA, Fuchs E (2011) Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci USA 108:2270-2275
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 2270-2275
    • Zhang, H.1    Pasolli, H.A.2    Fuchs, E.3
  • 31
    • 84897896235 scopus 로고    scopus 로고
    • Elevated YAP and its downstream targets CCN1 and CCN2 in basal cell carcinoma: Impact on keratinocyte proliferation and stromal cell activation
    • 3969992 1:CAS:528:DC%2BC2cXkslWnt7c%3D 24485923
    • Quan T, Xu Y, Qin Z, Robichaud P, Betcher S, Calderone K et al (2014) Elevated YAP and its downstream targets CCN1 and CCN2 in basal cell carcinoma: impact on keratinocyte proliferation and stromal cell activation. Am J Pathol 184:937-943
    • (2014) Am J Pathol , vol.184 , pp. 937-943
    • Quan, T.1    Xu, Y.2    Qin, Z.3    Robichaud, P.4    Betcher, S.5    Calderone, K.6
  • 32
    • 84890996895 scopus 로고    scopus 로고
    • Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma
    • 3938155 1:CAS:528:DC%2BC3sXhtlCnt7vK 23897276
    • Nallet-Staub F, Marsaud V, Li L, Gilbert C, Dodier S, Bataille V et al (2014) Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma. J Invest Dermatol 134:123-132
    • (2014) J Invest Dermatol , vol.134 , pp. 123-132
    • Nallet-Staub, F.1    Marsaud, V.2    Li, L.3    Gilbert, C.4    Dodier, S.5    Bataille, V.6
  • 34
    • 0035971572 scopus 로고    scopus 로고
    • Function and regulation of AP-1 subunits in skin physiology and pathology
    • 1:CAS:528:DC%2BD3MXjslyrsrg%3D 11402337
    • Angel P, Szabowski A, Schorpp-Kistner M (2001) Function and regulation of AP-1 subunits in skin physiology and pathology. Oncogene 20:2413-2423
    • (2001) Oncogene , vol.20 , pp. 2413-2423
    • Angel, P.1    Szabowski, A.2    Schorpp-Kistner, M.3
  • 35
    • 0030475369 scopus 로고    scopus 로고
    • Transcription factor regulation of epidermal keratinocyte gene expression
    • 1:CAS:528:DyaK2sXjtFWm 8983019
    • Eckert RL, Welter JF (1996) Transcription factor regulation of epidermal keratinocyte gene expression. Mol Biol Rep 23:59-70
    • (1996) Mol Biol Rep , vol.23 , pp. 59-70
    • Eckert, R.L.1    Welter, J.F.2
  • 36
    • 0034660640 scopus 로고    scopus 로고
    • JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression
    • 203376 1:CAS:528:DC%2BD3cXmtFCqs7w%3D 10856241
    • Passegue E, Wagner EF (2000) JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression. EMBO J 19:2969-2979
    • (2000) EMBO J , vol.19 , pp. 2969-2979
    • Passegue, E.1    Wagner, E.F.2
  • 37
  • 38
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • 1:CAS:528:DC%2BD3MXjslyrsro%3D 11402335
    • Shaulian E, Karin M (2001) AP-1 in cell proliferation and survival. Oncogene 20:2390-2400
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 39
    • 79952009551 scopus 로고    scopus 로고
    • A preliminary study of differentially expressed genes in expanded skin and normal skin: Implications for adult skin regeneration
    • 21286735
    • Yang M, Liang Y, Sheng L, Shen G, Liu K, Gu B et al (2011) A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration. Arch Dermatol Res 303:125-133
    • (2011) Arch Dermatol Res , vol.303 , pp. 125-133
    • Yang, M.1    Liang, Y.2    Sheng, L.3    Shen, G.4    Liu, K.5    Gu, B.6
  • 40
    • 0029616040 scopus 로고
    • Cyclic strain causes heterogeneous induction of transcription factors, AP-1, CRE binding protein and NF-kB, in endothelial cells: Species and vascular bed diversity
    • 1:STN:280:DyaK283jsFOnsg%3D%3D 8666588
    • Du W, Mills I, Sumpio BE (1995) Cyclic strain causes heterogeneous induction of transcription factors, AP-1, CRE binding protein and NF-kB, in endothelial cells: species and vascular bed diversity. J Biomech 28:1485-1491
    • (1995) J Biomech , vol.28 , pp. 1485-1491
    • Du, W.1    Mills, I.2    Sumpio, B.E.3
  • 41
    • 0031601849 scopus 로고    scopus 로고
    • Effects of mechanical forces on signal transduction and gene expression in endothelial cells
    • 1:CAS:528:DyaK1cXptF2itw%3D%3D 9453297
    • Chien S, Li S, Shyy YJ (1998) Effects of mechanical forces on signal transduction and gene expression in endothelial cells. Hypertension 31:162-169
    • (1998) Hypertension , vol.31 , pp. 162-169
    • Chien, S.1    Li, S.2    Shyy, Y.J.3
  • 42
    • 0032829051 scopus 로고    scopus 로고
    • AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells
    • 1:CAS:528:DyaK1MXls1ajsLc%3D 10444406
    • Park JM, Adam RM, Peters CA, Guthrie PD, Sun Z, Klagsbrun M et al (1999) AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells. Am J Physiol 277:C294-C301
    • (1999) Am J Physiol , vol.277 , pp. 294-C301
    • Park, J.M.1    Adam, R.M.2    Peters, C.A.3    Guthrie, P.D.4    Sun, Z.5    Klagsbrun, M.6
  • 43
    • 0035223876 scopus 로고    scopus 로고
    • Stretch-mediated activation of selective MAPK subtypes and potentiation of AP-1 binding in human osteoblastic cells
    • 1949988 1:CAS:528:DC%2BD3MXhtlKms74%3D 11474129
    • Peverali FA, Basdra EK, Papavassiliou AG (2001) Stretch-mediated activation of selective MAPK subtypes and potentiation of AP-1 binding in human osteoblastic cells. Mol Med 7:68-78
    • (2001) Mol Med , vol.7 , pp. 68-78
    • Peverali, F.A.1    Basdra, E.K.2    Papavassiliou, A.G.3
  • 44
    • 0141445981 scopus 로고    scopus 로고
    • Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: Implications in asthma
    • 1:CAS:528:DC%2BD3sXot1Kmsr4%3D
    • Kumar A, Lnu S, Malya R, Barron D, Moore J, Corry DB et al (2003) Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma. FASEB J Off Publ Fed Am Soc Exp Biol 17:1800-1811
    • (2003) FASEB J off Publ Fed Am Soc Exp Biol , vol.17 , pp. 1800-1811
    • Kumar, A.1    Lnu, S.2    Malya, R.3    Barron, D.4    Moore, J.5    Corry, D.B.6
  • 45
    • 33947428785 scopus 로고    scopus 로고
    • The effect of mechanical stretch on cyclooxygenase type 2 expression and activator protein-1 and nuclear factor-kappaB activity in human amnion cells
    • 1:CAS:528:DC%2BD2sXjvVOhtb4%3D 17218407
    • Mohan AR, Sooranna SR, Lindstrom TM, Johnson MR, Bennett PR (2007) The effect of mechanical stretch on cyclooxygenase type 2 expression and activator protein-1 and nuclear factor-kappaB activity in human amnion cells. Endocrinology 148:1850-1857
    • (2007) Endocrinology , vol.148 , pp. 1850-1857
    • Mohan, A.R.1    Sooranna, S.R.2    Lindstrom, T.M.3    Johnson, M.R.4    Bennett, P.R.5
  • 46
    • 54049106210 scopus 로고    scopus 로고
    • Stretch-induced activation of the transcription factor activator protein-1 controls monocyte chemoattractant protein-1 expression during arteriogenesis
    • 1:CAS:528:DC%2BD1cXhtVeisL%2FE 18669921
    • Demicheva E, Hecker M, Korff T (2008) Stretch-induced activation of the transcription factor activator protein-1 controls monocyte chemoattractant protein-1 expression during arteriogenesis. Circ Res 103:477-484
    • (2008) Circ Res , vol.103 , pp. 477-484
    • Demicheva, E.1    Hecker, M.2    Korff, T.3
  • 47
    • 33645773666 scopus 로고    scopus 로고
    • Local force and geometry sensing regulate cell functions
    • 1:CAS:528:DC%2BD28Xjt12qsLs%3D 16607289
    • Vogel V, Sheetz M (2006) Local force and geometry sensing regulate cell functions. Nat Rev Mol Cell Biol 7:265-275
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 265-275
    • Vogel, V.1    Sheetz, M.2
  • 48
    • 76349102806 scopus 로고    scopus 로고
    • Stretch-activated ion channels: What are they?
    • 2924431 1:CAS:528:DC%2BC3cXjs1Gis7g%3D 20134028
    • Sachs F (2010) Stretch-activated ion channels: what are they? Physiology 25:50-56
    • (2010) Physiology , vol.25 , pp. 50-56
    • Sachs, F.1
  • 49
    • 34249865351 scopus 로고    scopus 로고
    • Universal physical responses to stretch in the living cell
    • 2440511 1:CAS:528:DC%2BD2sXlvVyktLk%3D 17538621
    • Trepat X, Deng L, An SS, Navajas D, Tschumperlin DJ, Gerthoffer WT et al (2007) Universal physical responses to stretch in the living cell. Nature 447:592-595
    • (2007) Nature , vol.447 , pp. 592-595
    • Trepat, X.1    Deng, L.2    An, S.S.3    Navajas, D.4    Tschumperlin, D.J.5    Gerthoffer, W.T.6
  • 50
    • 0030064019 scopus 로고    scopus 로고
    • Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor
    • 507156 1:CAS:528:DyaK28XhvVais7k%3D 8613532
    • Bikle DD, Ratnam A, Mauro T, Harris J, Pillai S (1996) Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor. J Clin Investig 97:1085-1093
    • (1996) J Clin Investig , vol.97 , pp. 1085-1093
    • Bikle, D.D.1    Ratnam, A.2    Mauro, T.3    Harris, J.4    Pillai, S.5
  • 51
    • 84864838468 scopus 로고    scopus 로고
    • Calcium signaling is gated by a mechanical threshold in three-dimensional environments
    • 3412325 22870383
    • Ruder WC, Pratt ED, Brandy NZ, LaVan DA, LeDuc PR, Antaki JF (2012) Calcium signaling is gated by a mechanical threshold in three-dimensional environments. Sci Rep 2:554
    • (2012) Sci Rep , vol.2 , pp. 554
    • Ruder, W.C.1    Pratt, E.D.2    Brandy, N.Z.3    Lavan, D.A.4    Leduc, P.R.5    Antaki, J.F.6
  • 52
    • 84877788231 scopus 로고    scopus 로고
    • The mechanical environment modulates intracellular calcium oscillation activities of myofibroblasts
    • 3653915 1:CAS:528:DC%2BC3sXot1ygt7Y%3D 23691248
    • Godbout C, Follonier Castella L, Smith EA, Talele N, Chow ML, Garonna A et al (2013) The mechanical environment modulates intracellular calcium oscillation activities of myofibroblasts. PLoS One 8:e64560
    • (2013) PLoS One , vol.8 , pp. 64560
    • Godbout, C.1    Follonier Castella, L.2    Smith, E.A.3    Talele, N.4    Chow, M.L.5    Garonna, A.6
  • 53
    • 84861353004 scopus 로고    scopus 로고
    • Forcing stem cells to behave: A biophysical perspective of the cellular microenvironment
    • Sun Y, Chen CS, Fu J (2012) Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment. Annual Rev Biophys 41:519-542
    • (2012) Annual Rev Biophys , vol.41 , pp. 519-542
    • Sun, Y.1    Chen, C.S.2    Fu, J.3
  • 54
    • 0036840333 scopus 로고    scopus 로고
    • Mechanosensitivity of N-type calcium channel currents
    • 1302342 1:CAS:528:DC%2BD38Xos1Crsb8%3D 12414690
    • Calabrese B, Tabarean IV, Juranka P, Morris CE (2002) Mechanosensitivity of N-type calcium channel currents. Biophys J 83:2560-2574
    • (2002) Biophys J , vol.83 , pp. 2560-2574
    • Calabrese, B.1    Tabarean, I.V.2    Juranka, P.3    Morris, C.E.4
  • 57
    • 0033966937 scopus 로고    scopus 로고
    • The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation
    • 1:CAS:528:DC%2BD3cXntlegug%3D%3D 10625662
    • Oda Y, Tu CL, Chang W, Crumrine D, Komuves L, Mauro T et al (2000) The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation. J Biol Chem 275:1183-1190
    • (2000) J Biol Chem , vol.275 , pp. 1183-1190
    • Oda, Y.1    Tu, C.L.2    Chang, W.3    Crumrine, D.4    Komuves, L.5    Mauro, T.6
  • 58
    • 0035798614 scopus 로고    scopus 로고
    • The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes
    • 1:CAS:528:DC%2BD3MXosVKgsLs%3D 11500521
    • Tu CL, Chang W, Bikle DD (2001) The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes. J Biol Chem 276:41079-41085
    • (2001) J Biol Chem , vol.276 , pp. 41079-41085
    • Tu, C.L.1    Chang, W.2    Bikle, D.D.3
  • 59
    • 2942751868 scopus 로고    scopus 로고
    • Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
    • 1:CAS:528:DC%2BD2cXksVaisbw%3D 15146194
    • Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T et al (2004) Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 6:499-506
    • (2004) Nat Cell Biol , vol.6 , pp. 499-506
    • Zou, Y.1    Akazawa, H.2    Qin, Y.3    Sano, M.4    Takano, H.5    Minamino, T.6
  • 60
    • 33750366860 scopus 로고    scopus 로고
    • G protein-coupled receptors sense fluid shear stress in endothelial cells
    • 1622845 17030791
    • Chachisvilis M, Zhang YL, Frangos JA (2006) G protein-coupled receptors sense fluid shear stress in endothelial cells. Proc Natl Acad Sci USA 103:15463-15468
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15463-15468
    • Chachisvilis, M.1    Zhang, Y.L.2    Frangos, J.A.3
  • 61
    • 77951520888 scopus 로고    scopus 로고
    • G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: The role of protein kinase C
    • 2859538 1:CAS:528:DC%2BC3cXltFOgtrs%3D 20194499
    • Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA (2010) G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C. J Biol Chem 285:13748-13760
    • (2010) J Biol Chem , vol.285 , pp. 13748-13760
    • Malhotra, R.1    D'Souza, K.M.2    Staron, M.L.3    Birukov, K.G.4    Bodi, I.5    Akhter, S.A.6
  • 62
    • 57149121154 scopus 로고    scopus 로고
    • Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction
    • 1:CAS:528:DC%2BD1cXhtl2gsb7P 18987636
    • Mederos y Schnitzler M, Storch U, Meibers S, Nurwakagari P, Breit A, Essin K et al (2008) Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction. EMBO J 27:3092-3103
    • (2008) EMBO J , vol.27 , pp. 3092-3103
    • Mederos Schnitzler Y, M.1    Storch, U.2    Meibers, S.3    Nurwakagari, P.4    Breit, A.5    Essin, K.6
  • 64
    • 79955385581 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts
    • 3083230 21357420
    • D'Souza KM, Malhotra R, Philip JL, Staron ML, Theccanat T, Jeevanandam V et al (2011) G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts. J Biol Chem 286:15507-15516
    • (2011) J Biol Chem , vol.286 , pp. 15507-15516
    • D'Souza, K.M.1    Malhotra, R.2    Philip, J.L.3    Staron, M.L.4    Theccanat, T.5    Jeevanandam, V.6
  • 65
    • 79954902401 scopus 로고    scopus 로고
    • The calcium-sensing receptor-dependent regulation of cell-cell adhesion and keratinocyte differentiation requires Rho and filamin A
    • 3078217 1:CAS:528:DC%2BC3MXks12itbc%3D 21209619
    • Tu CL, Chang W, Bikle DD (2011) The calcium-sensing receptor-dependent regulation of cell-cell adhesion and keratinocyte differentiation requires Rho and filamin A. J Invest Dermatol 131:1119-1128
    • (2011) J Invest Dermatol , vol.131 , pp. 1119-1128
    • Tu, C.L.1    Chang, W.2    Bikle, D.D.3
  • 66
    • 41249083701 scopus 로고    scopus 로고
    • Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes
    • 1:CAS:528:DC%2BD1cXhtlyisbY%3D 18065418
    • Tu CL, Chang W, Xie Z, Bikle DD (2008) Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes. J Biol Chem 283:3519-3528
    • (2008) J Biol Chem , vol.283 , pp. 3519-3528
    • Tu, C.L.1    Chang, W.2    Xie, Z.3    Bikle, D.D.4
  • 67
    • 84866372350 scopus 로고    scopus 로고
    • Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function
    • 3434298 1:CAS:528:DC%2BC38Xntlyqsbk%3D 22622426
    • Tu CL, Crumrine DA, Man MQ, Chang W, Elalieh H, You M et al (2012) Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function. J Invest Dermatol 132:2350-2359
    • (2012) J Invest Dermatol , vol.132 , pp. 2350-2359
    • Tu, C.L.1    Crumrine, D.A.2    Man, M.Q.3    Chang, W.4    Elalieh, H.5    You, M.6
  • 68
    • 77953622288 scopus 로고    scopus 로고
    • Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes
    • 1:CAS:528:DC%2BC3cXnsVyisLk%3D 20182444
    • Tsutsumi M, Denda S, Ikeyama K, Goto M, Denda M (2010) Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes. J Invest Dermatol 130:1945-1948
    • (2010) J Invest Dermatol , vol.130 , pp. 1945-1948
    • Tsutsumi, M.1    Denda, S.2    Ikeyama, K.3    Goto, M.4    Denda, M.5
  • 69
    • 84900789513 scopus 로고    scopus 로고
    • TRP channels in the skin
    • 4009000 1:CAS:528:DC%2BC2cXmvV2isb0%3D 24372189
    • Toth BI, Olah A, Szollosi AG, Biro T (2014) TRP channels in the skin. Br J Pharmacol 171:2568-2581
    • (2014) Br J Pharmacol , vol.171 , pp. 2568-2581
    • Toth, B.I.1    Olah, A.2    Szollosi, A.G.3    Biro, T.4
  • 70
    • 77953613538 scopus 로고    scopus 로고
    • Topical application of TRPA1 agonists and brief cold exposure accelerate skin permeability barrier recovery
    • 1:CAS:528:DC%2BC3cXnsVyisb0%3D 20182443
    • Denda M, Tsutsumi M, Goto M, Ikeyama K, Denda S (2010) Topical application of TRPA1 agonists and brief cold exposure accelerate skin permeability barrier recovery. J Invest Dermatol 130:1942-1945
    • (2010) J Invest Dermatol , vol.130 , pp. 1942-1945
    • Denda, M.1    Tsutsumi, M.2    Goto, M.3    Ikeyama, K.4    Denda, S.5
  • 72
    • 79954952532 scopus 로고    scopus 로고
    • Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1
    • 1:CAS:528:DC%2BC3MXks12itbk%3D 21248768
    • Toth BI, Dobrosi N, Dajnoki A, Czifra G, Olah A, Szollosi AG et al (2011) Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1. J Invest Dermatol 131:1095-1104
    • (2011) J Invest Dermatol , vol.131 , pp. 1095-1104
    • Toth, B.I.1    Dobrosi, N.2    Dajnoki, A.3    Czifra, G.4    Olah, A.5    Szollosi, A.G.6
  • 73
    • 20244381982 scopus 로고    scopus 로고
    • A hot new twist to hair biology: Involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control
    • 1602392 1:CAS:528:DC%2BD2MXjsFaks70%3D 15793280
    • Bodo E, Biro T, Telek A, Czifra G, Griger Z, Toth BI et al (2005) A hot new twist to hair biology: involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control. Am J Pathol 166:985-998
    • (2005) Am J Pathol , vol.166 , pp. 985-998
    • Bodo, E.1    Biro, T.2    Telek, A.3    Czifra, G.4    Griger, Z.5    Toth, B.I.6
  • 74
    • 0037216692 scopus 로고    scopus 로고
    • Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes
    • 1:CAS:528:DC%2BD3sXht1ShsQ%3D%3D 12490594
    • Southall MD, Li T, Gharibova LS, Pei Y, Nicol GD, Travers JB (2003) Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes. J Pharmacol Exp Ther 304:217-222
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 217-222
    • Southall, M.D.1    Li, T.2    Gharibova, L.S.3    Pei, Y.4    Nicol, G.D.5    Travers, J.B.6
  • 75
    • 84893402011 scopus 로고    scopus 로고
    • TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading
    • 3910592 24474754
    • O'Conor CJ, Leddy HA, Benefield HC, Liedtke WB, Guilak F (2014) TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. Proc Natl Acad Sci USA 111:1316-1321
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 1316-1321
    • O'Conor, C.J.1    Leddy, H.A.2    Benefield, H.C.3    Liedtke, W.B.4    Guilak, F.5
  • 76
    • 84867897084 scopus 로고    scopus 로고
    • Activation of TRPV4 strengthens the tight-junction barrier in human epidermal keratinocytes
    • 1:CAS:528:DC%2BC38XhvV2gsb7E 23108102
    • Akazawa Y, Yuki T, Yoshida H, Sugiyama Y, Inoue S (2013) Activation of TRPV4 strengthens the tight-junction barrier in human epidermal keratinocytes. Skin Pharmacol Physiol 26:15-21
    • (2013) Skin Pharmacol Physiol , vol.26 , pp. 15-21
    • Akazawa, Y.1    Yuki, T.2    Yoshida, H.3    Sugiyama, Y.4    Inoue, S.5
  • 77
    • 77953316839 scopus 로고    scopus 로고
    • The TRPV4 channel contributes to intercellular junction formation in keratinocytes
    • 2881798 1:CAS:528:DC%2BC3cXmvFaqsbc%3D 20413591
    • Sokabe T, Fukumi-Tominaga T, Yonemura S, Mizuno A, Tominaga M (2010) The TRPV4 channel contributes to intercellular junction formation in keratinocytes. J Biol Chem 285:18749-18758
    • (2010) J Biol Chem , vol.285 , pp. 18749-18758
    • Sokabe, T.1    Fukumi-Tominaga, T.2    Yonemura, S.3    Mizuno, A.4    Tominaga, M.5
  • 78
    • 84906315513 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer
    • 1:CAS:528:DC%2BC2cXmtlaisb4%3D 24643128
    • Fusi C, Materazzi S, Minocci D, Maio V, Oranges T, Massi D et al (2014) Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer. J Invest Dermatol 134:2408-2417
    • (2014) J Invest Dermatol , vol.134 , pp. 2408-2417
    • Fusi, C.1    Materazzi, S.2    Minocci, D.3    Maio, V.4    Oranges, T.5    Massi, D.6
  • 79
    • 0034068362 scopus 로고    scopus 로고
    • Connexins: A connection with the skin
    • 1:CAS:528:DC%2BD3cXivVeiurc%3D 10772382
    • Richard G (2000) Connexins: a connection with the skin. Exp Dermatol 9:77-96
    • (2000) Exp Dermatol , vol.9 , pp. 77-96
    • Richard, G.1
  • 80
    • 84867625991 scopus 로고    scopus 로고
    • Beyond gap junctions: Connexin43 and bone cell signaling
    • 3513515 1:CAS:528:DC%2BC38XhvVSlsLbJ 23041511
    • Plotkin LI, Bellido T (2013) Beyond gap junctions: Connexin43 and bone cell signaling. Bone 52:157-166
    • (2013) Bone , vol.52 , pp. 157-166
    • Plotkin, L.I.1    Bellido, T.2
  • 81
  • 82
    • 84857738933 scopus 로고    scopus 로고
    • Mechanical stress-activated integrin alpha5beta1 induces opening of connexin 43 hemichannels
    • 3295295 1:CAS:528:DC%2BC38XksVyht7w%3D 22331870
    • Batra N, Burra S, Siller-Jackson AJ, Gu S, Xia X, Weber GF et al (2012) Mechanical stress-activated integrin alpha5beta1 induces opening of connexin 43 hemichannels. Proc Natl Acad Sci USA 109:3359-3364
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3359-3364
    • Batra, N.1    Burra, S.2    Siller-Jackson, A.J.3    Gu, S.4    Xia, X.5    Weber, G.F.6
  • 83
    • 55549123031 scopus 로고    scopus 로고
    • Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading
    • 2546557 1:CAS:528:DC%2BD1cXhtFejsbnK 18676366
    • Siller-Jackson AJ, Burra S, Gu S, Xia X, Bonewald LF, Sprague E et al (2008) Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading. J Biol Chem 283:26374-26382
    • (2008) J Biol Chem , vol.283 , pp. 26374-26382
    • Siller-Jackson, A.J.1    Burra, S.2    Gu, S.3    Xia, X.4    Bonewald, L.F.5    Sprague, E.6
  • 85
    • 84898904766 scopus 로고    scopus 로고
    • Connexins: Sensors of epidermal integrity that are therapeutic targets
    • 1:CAS:528:DC%2BC2cXksVWku78%3D 24607543
    • Martin PE, Easton JA, Hodgins MB, Wright CS (2014) Connexins: sensors of epidermal integrity that are therapeutic targets. FEBS Lett 588:1304-1314
    • (2014) FEBS Lett , vol.588 , pp. 1304-1314
    • Martin, P.E.1    Easton, J.A.2    Hodgins, M.B.3    Wright, C.S.4
  • 86
    • 35649025431 scopus 로고    scopus 로고
    • Connexin levels regulate keratinocyte differentiation in the epidermis
    • 1:CAS:528:DC%2BD2sXhtFagtbfM 17693411
    • Langlois S, Maher AC, Manias JL, Shao Q, Kidder GM, Laird DW (2007) Connexin levels regulate keratinocyte differentiation in the epidermis. J Biol Chem 282:30171-30180
    • (2007) J Biol Chem , vol.282 , pp. 30171-30180
    • Langlois, S.1    Maher, A.C.2    Manias, J.L.3    Shao, Q.4    Kidder, G.M.5    Laird, D.W.6
  • 87
    • 2442417362 scopus 로고    scopus 로고
    • Connexins 26, 30, and 43: Differences among spontaneous, chronic, and accelerated human wound healing
    • 1:CAS:528:DC%2BD2cXkvVOru7k%3D 15140236
    • Brandner JM, Houdek P, Husing B, Kaiser C, Moll I (2004) Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing. J Invest Dermatol 122:1310-1320
    • (2004) J Invest Dermatol , vol.122 , pp. 1310-1320
    • Brandner, J.M.1    Houdek, P.2    Husing, B.3    Kaiser, C.4    Moll, I.5
  • 88
    • 79951580586 scopus 로고    scopus 로고
    • Cell adhesion and communication proteins are differentially expressed in melanoma progression model
    • 1:CAS:528:DC%2BC3MXhvFWgtbw%3D 21193224
    • Rezze GG, Fregnani JH, Duprat J, Landman G (2011) Cell adhesion and communication proteins are differentially expressed in melanoma progression model. Hum Pathol 42:409-418
    • (2011) Hum Pathol , vol.42 , pp. 409-418
    • Rezze, G.G.1    Fregnani, J.H.2    Duprat, J.3    Landman, G.4
  • 89
    • 5644249331 scopus 로고    scopus 로고
    • The gap junction protein connexin32 is a mouse lung tumor suppressor
    • 1:CAS:528:DC%2BD2cXosFyntrw%3D 15492231
    • King TJ, Lampe PD (2004) The gap junction protein connexin32 is a mouse lung tumor suppressor. Cancer Res 64:7191-7196
    • (2004) Cancer Res , vol.64 , pp. 7191-7196
    • King, T.J.1    Lampe, P.D.2
  • 90
    • 84892665526 scopus 로고    scopus 로고
    • Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo
    • 3894339 1:CAS:528:DC%2BC2cXptFOltQ%3D%3D 24297173
    • Ableser MJ, Penuela S, Lee J, Shao Q, Laird DW (2014) Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo. J Biol Chem 289:1592-1603
    • (2014) J Biol Chem , vol.289 , pp. 1592-1603
    • Ableser, M.J.1    Penuela, S.2    Lee, J.3    Shao, Q.4    Laird, D.W.5
  • 91
    • 77957332682 scopus 로고    scopus 로고
    • Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels
    • 3062430 1:CAS:528:DC%2BC3cXht1WmtbbP 20813920
    • Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ et al (2010) Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science 330:55-60
    • (2010) Science , vol.330 , pp. 55-60
    • Coste, B.1    Mathur, J.2    Schmidt, M.3    Earley, T.J.4    Ranade, S.5    Petrus, M.J.6
  • 92
    • 84865295955 scopus 로고    scopus 로고
    • Piezo1: Properties of a cation selective mechanical channel
    • 3508900 1:CAS:528:DC%2BC3sXhvFCrtr0%3D 22790400
    • Gottlieb PA, Sachs F (2012) Piezo1: properties of a cation selective mechanical channel. Channels 6:214-219
    • (2012) Channels , vol.6 , pp. 214-219
    • Gottlieb, P.A.1    Sachs, F.2
  • 93
    • 84862777142 scopus 로고    scopus 로고
    • Piezo proteins are pore-forming subunits of mechanically activated channels
    • 3297710 1:CAS:528:DC%2BC38XisVKrurg%3D 22343900
    • Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS et al (2012) Piezo proteins are pore-forming subunits of mechanically activated channels. Nature 483:176-181
    • (2012) Nature , vol.483 , pp. 176-181
    • Coste, B.1    Xiao, B.2    Santos, J.S.3    Syeda, R.4    Grandl, J.5    Spencer, K.S.6
  • 95
    • 84909619334 scopus 로고    scopus 로고
    • Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells
    • 1:CAS:528:DC%2BC2cXhvVWmsLzN 25349416
    • Pathak MM, Nourse JL, Tran T, Hwe J, Arulmoli J, Le DT et al (2014) Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells. Proc Natl Acad Sci USA 111:16148-16153
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 16148-16153
    • Pathak, M.M.1    Nourse, J.L.2    Tran, T.3    Hwe, J.4    Arulmoli, J.5    Le, D.T.6
  • 96
    • 84901680112 scopus 로고    scopus 로고
    • Piezo2 is required for Merkel-cell mechanotransduction
    • 4039622 1:CAS:528:DC%2BC2cXoslCrt7o%3D 24717433
    • Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z et al (2014) Piezo2 is required for Merkel-cell mechanotransduction. Nature 509:622-626
    • (2014) Nature , vol.509 , pp. 622-626
    • Woo, S.H.1    Ranade, S.2    Weyer, A.D.3    Dubin, A.E.4    Baba, Y.5    Qiu, Z.6
  • 97
    • 10644290199 scopus 로고    scopus 로고
    • TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
    • 1:CAS:528:DC%2BD2cXhtVGmtLnJ 15483558
    • Corey DP, Garcia-Anoveros J, Holt JR, Kwan KY, Lin SY, Vollrath MA et al (2004) TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 432:723-730
    • (2004) Nature , vol.432 , pp. 723-730
    • Corey, D.P.1    Garcia-Anoveros, J.2    Holt, J.R.3    Kwan, K.Y.4    Lin, S.Y.5    Vollrath, M.A.6
  • 98
    • 78049440285 scopus 로고    scopus 로고
    • Rami Reddy V, Semeriva M, Perrin L, Lalevee N. Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart
    • 2932686 20824071
    • Senatore S (2010) Rami Reddy V, Semeriva M, Perrin L, Lalevee N. Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart. PLoS Genet 6:e1001088
    • (2010) PLoS Genet , vol.6 , pp. 1001088
    • Senatore, S.1
  • 99
    • 38849207782 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid type 1 channels act as mechanoreceptors and cause substance P release and sensory activation in rat kidneys
    • 1:CAS:528:DC%2BD1cXit1yks74%3D 18032552
    • Feng NH, Lee HH, Shiang JC, Ma MC (2008) Transient receptor potential vanilloid type 1 channels act as mechanoreceptors and cause substance P release and sensory activation in rat kidneys. Am J Physiol Renal Physiol 294:F316-F325
    • (2008) Am J Physiol Renal Physiol , vol.294 , pp. 316-F325
    • Feng, N.H.1    Lee, H.H.2    Shiang, J.C.3    Ma, M.C.4
  • 100
    • 0038604287 scopus 로고    scopus 로고
    • Impaired pressure sensation in mice lacking TRPV4
    • 1:CAS:528:DC%2BD3sXksF2it7s%3D 12692122
    • Suzuki M, Mizuno A, Kodaira K, Imai M (2003) Impaired pressure sensation in mice lacking TRPV4. J Biol Chem 278:22664-22668
    • (2003) J Biol Chem , vol.278 , pp. 22664-22668
    • Suzuki, M.1    Mizuno, A.2    Kodaira, K.3    Imai, M.4
  • 101
    • 23944499058 scopus 로고    scopus 로고
    • Mechanical stimulation prevents osteocyte apoptosis: Requirement of integrins, Src kinases, and ERKs
    • 1:CAS:528:DC%2BD2MXhtVWksb%2FI 15872009
    • Plotkin LI, Mathov I, Aguirre JI, Parfitt AM, Manolagas SC, Bellido T (2005) Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs. Am J Physiol Cell Physiol 289:C633-C643
    • (2005) Am J Physiol Cell Physiol , vol.289 , pp. 633-C643
    • Plotkin, L.I.1    Mathov, I.2    Aguirre, J.I.3    Parfitt, A.M.4    Manolagas, S.C.5    Bellido, T.6
  • 102
    • 33846026749 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone
    • 1:CAS:528:DC%2BD28XhtVOrtr3F 16908522
    • Robinson JA, Chatterjee-Kishore M, Yaworsky PJ, Cullen DM, Zhao W, Li C et al (2006) Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone. J Biol Chem 281:31720-31728
    • (2006) J Biol Chem , vol.281 , pp. 31720-31728
    • Robinson, J.A.1    Chatterjee-Kishore, M.2    Yaworsky, P.J.3    Cullen, D.M.4    Zhao, W.5    Li, C.6
  • 103
    • 84892502745 scopus 로고    scopus 로고
    • Injury-triggered Akt phosphorylation of Cx43: A ZO-1-driven molecular switch that regulates gap junction size
    • 3889401 1:CAS:528:DC%2BC2cXivFSgtL0%3D 24213533
    • Dunn CA, Lampe PD (2014) Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size. J Cell Sci 127:455-464
    • (2014) J Cell Sci , vol.127 , pp. 455-464
    • Dunn, C.A.1    Lampe, P.D.2
  • 104
    • 35748935253 scopus 로고    scopus 로고
    • Abnormal connexin expression underlies delayed wound healing in diabetic skin
    • 1:CAS:528:DC%2BD2sXhtlWitLzF 17717278
    • Wang CM, Lincoln J, Cook JE, Becker DL (2007) Abnormal connexin expression underlies delayed wound healing in diabetic skin. Diabetes 56:2809-2817
    • (2007) Diabetes , vol.56 , pp. 2809-2817
    • Wang, C.M.1    Lincoln, J.2    Cook, J.E.3    Becker, D.L.4
  • 105
    • 69249096952 scopus 로고    scopus 로고
    • Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43
    • 2727665 1:CAS:528:DC%2BD1MXpvFeju7s%3D 19679555
    • Villares GJ, Dobroff AS, Wang H, Zigler M, Melnikova VO, Huang L et al (2009) Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43. Cancer Res 69:6730-6737
    • (2009) Cancer Res , vol.69 , pp. 6730-6737
    • Villares, G.J.1    Dobroff, A.S.2    Wang, H.3    Zigler, M.4    Melnikova, V.O.5    Huang, L.6
  • 106
    • 84886771443 scopus 로고    scopus 로고
    • The protein phosphatase 2A regulatory subunit Ppp2r2a is required for Connexin-43 dephosphorylation during epidermal barrier acquisition
    • 1:CAS:528:DC%2BC3sXhslWntrnL 24433183
    • Gerner L, Youssef G, O'Shaughnessy RF (2013) The protein phosphatase 2A regulatory subunit Ppp2r2a is required for Connexin-43 dephosphorylation during epidermal barrier acquisition. Exp Dermatol 22:754-756
    • (2013) Exp Dermatol , vol.22 , pp. 754-756
    • Gerner, L.1    Youssef, G.2    O'Shaughnessy, R.F.3
  • 108
    • 84867864442 scopus 로고    scopus 로고
    • PDZK1 upregulation in estrogen-related hyperpigmentation in melasma
    • 1:CAS:528:DC%2BC38Xos1emtLs%3D 22696060
    • Kim NH, Cheong KA, Lee TR, Lee AY (2012) PDZK1 upregulation in estrogen-related hyperpigmentation in melasma. J Invest Dermatol 132:2622-2631
    • (2012) J Invest Dermatol , vol.132 , pp. 2622-2631
    • Kim, N.H.1    Cheong, K.A.2    Lee, T.R.3    Lee, A.Y.4
  • 109
    • 84885176963 scopus 로고    scopus 로고
    • Mechanosensitive microRNAs-role in endothelial responses to shear stress and redox state
    • 3762952 1:CAS:528:DC%2BC3sXhtVWmurfF 23727269
    • Marin T, Gongol B, Chen Z, Woo B, Subramaniam S, Chien S et al (2013) Mechanosensitive microRNAs-role in endothelial responses to shear stress and redox state. Free Radic Biol Med 64:61-68
    • (2013) Free Radic Biol Med , vol.64 , pp. 61-68
    • Marin, T.1    Gongol, B.2    Chen, Z.3    Woo, B.4    Subramaniam, S.5    Chien, S.6
  • 110
    • 84862165682 scopus 로고    scopus 로고
    • MicroRNA modulate alveolar epithelial response to cyclic stretch
    • 1:CAS:528:DC%2BC38XhslGqu7jL
    • Yehya N, Yerrapureddy A, Tobias J, Margulies SS (2012) MicroRNA modulate alveolar epithelial response to cyclic stretch. BMC Genom 13:154
    • (2012) BMC Genom , vol.13 , pp. 154
    • Yehya, N.1    Yerrapureddy, A.2    Tobias, J.3    Margulies, S.S.4
  • 111
    • 79957644371 scopus 로고    scopus 로고
    • MicroRNAs in skin and wound healing
    • 3110888 1:CAS:528:DC%2BC3MXot1Oitrg%3D 20959495
    • Banerjee J, Chan YC, Sen CK (2011) MicroRNAs in skin and wound healing. Physiol Genomics 43:543-556
    • (2011) Physiol Genomics , vol.43 , pp. 543-556
    • Banerjee, J.1    Chan, Y.C.2    Sen, C.K.3
  • 112
    • 84655167961 scopus 로고    scopus 로고
    • MicroRNAs as novel players in skin development, homeostasis and disease
    • 1:CAS:528:DC%2BC38XivFOqsbY%3D 21824129
    • Schneider MR (2012) MicroRNAs as novel players in skin development, homeostasis and disease. Br J Dermatol 166:22-28
    • (2012) Br J Dermatol , vol.166 , pp. 22-28
    • Schneider, M.R.1
  • 114
    • 84870551751 scopus 로고    scopus 로고
    • Soft tissue mechanotransduction in wound healing and fibrosis
    • 1:CAS:528:DC%2BC38XhvVSlsrrM 23036529
    • Wong VW, Longaker MT, Gurtner GC (2012) Soft tissue mechanotransduction in wound healing and fibrosis. Semin Cell Dev Biol 23:981-986
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 981-986
    • Wong, V.W.1    Longaker, M.T.2    Gurtner, G.C.3
  • 115
    • 77955424982 scopus 로고    scopus 로고
    • Mechanical receptor-related mechanisms in scar management: A review and hypothesis
    • 1:CAS:528:DC%2BC3cXpsF2ks78%3D 20375759
    • Yagmur C, Akaishi S, Ogawa R, Guneren E (2010) Mechanical receptor-related mechanisms in scar management: a review and hypothesis. Plast Reconstr Surg 126:426-434
    • (2010) Plast Reconstr Surg , vol.126 , pp. 426-434
    • Yagmur, C.1    Akaishi, S.2    Ogawa, R.3    Guneren, E.4
  • 116
    • 77949488939 scopus 로고    scopus 로고
    • MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity
    • 3717387 1:CAS:528:DC%2BC3cXjs1Ontrg%3D 20153722
    • Weber M, Baker MB, Moore JP, Searles CD (2010) MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity. Biochem Biophys Res Commun 393:643-648
    • (2010) Biochem Biophys Res Commun , vol.393 , pp. 643-648
    • Weber, M.1    Baker, M.B.2    Moore, J.P.3    Searles, C.D.4
  • 117
    • 84900817879 scopus 로고    scopus 로고
    • MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells
    • 3989748 1:CAS:528:DC%2BC2cXns1Grsb4%3D 24486510
    • Weber M, Kim S, Patterson N, Rooney K, Searles CD (2014) MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells. Am J Physiol Heart Circ Physiol 306:H1192-H1203
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , pp. 1192-H1203
    • Weber, M.1    Kim, S.2    Patterson, N.3    Rooney, K.4    Searles, C.D.5
  • 118
    • 84867630159 scopus 로고    scopus 로고
    • Mechanical stretch modulates microRNA 21 expression, participating in proliferation and apoptosis in cultured human aortic smooth muscle cells
    • 3474731 1:CAS:528:DC%2BC38Xhs1WrsrjO 23082189
    • Song J, Hu B, Qu H, Bi C, Huang X, Zhang M (2012) Mechanical stretch modulates microRNA 21 expression, participating in proliferation and apoptosis in cultured human aortic smooth muscle cells. PLoS One 7:e47657
    • (2012) PLoS One , vol.7 , pp. 47657
    • Song, J.1    Hu, B.2    Qu, H.3    Bi, C.4    Huang, X.5    Zhang, M.6
  • 119
    • 84869177920 scopus 로고    scopus 로고
    • MiR-21 regulates skin wound healing by targeting multiple aspects of the healing process
    • 23159215
    • Wang T, Feng Y, Sun H, Zhang L, Hao L, Shi C et al (2012) miR-21 regulates skin wound healing by targeting multiple aspects of the healing process. Am J Pathol 181:1911-1920
    • (2012) Am J Pathol , vol.181 , pp. 1911-1920
    • Wang, T.1    Feng, Y.2    Sun, H.3    Zhang, L.4    Hao, L.5    Shi, C.6
  • 120
    • 84865516535 scopus 로고    scopus 로고
    • Induction of specific microRNAs inhibits cutaneous wound healing
    • 3436197 1:CAS:528:DC%2BC38Xht1Cgtr7J 22773832
    • Pastar I, Khan AA, Stojadinovic O, Lebrun EA, Medina MC, Brem H et al (2012) Induction of specific microRNAs inhibits cutaneous wound healing. J Biol Chem 287:29324-29335
    • (2012) J Biol Chem , vol.287 , pp. 29324-29335
    • Pastar, I.1    Khan, A.A.2    Stojadinovic, O.3    Lebrun, E.A.4    Medina, M.C.5    Brem, H.6
  • 121
    • 84874786767 scopus 로고    scopus 로고
    • Extracellular matrix remodeling: The common denominator in connective tissue diseases. Possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure
    • 3593693 1:CAS:528:DC%2BC3sXjslWjsbY%3D 23046407
    • Karsdal MA, Nielsen MJ, Sand JM, Henriksen K, Genovese F, Bay-Jensen AC et al (2013) Extracellular matrix remodeling: the common denominator in connective tissue diseases. Possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure. Assay Drug Dev Technol 11:70-92
    • (2013) Assay Drug Dev Technol , vol.11 , pp. 70-92
    • Karsdal, M.A.1    Nielsen, M.J.2    Sand, J.M.3    Henriksen, K.4    Genovese, F.5    Bay-Jensen, A.C.6
  • 122
    • 72949104604 scopus 로고    scopus 로고
    • Surface morphology and mechanical properties of fibroblasts from scleroderma patients
    • 18624756
    • Reich A, Meurer M, Eckes B, Friedrichs J, Muller DJ (2009) Surface morphology and mechanical properties of fibroblasts from scleroderma patients. J Cell Mol Med 13:1644-1652
    • (2009) J Cell Mol Med , vol.13 , pp. 1644-1652
    • Reich, A.1    Meurer, M.2    Eckes, B.3    Friedrichs, J.4    Muller, D.J.5
  • 123
    • 84880841994 scopus 로고    scopus 로고
    • Mechanobiological dysregulation of the epidermis and dermis in skin disorders and in degeneration
    • 3822886 23672502
    • Ogawa R, Hsu CK (2013) Mechanobiological dysregulation of the epidermis and dermis in skin disorders and in degeneration. J Cell Mol Med 17:817-822
    • (2013) J Cell Mol Med , vol.17 , pp. 817-822
    • Ogawa, R.1    Hsu, C.K.2
  • 124
    • 84880316996 scopus 로고    scopus 로고
    • MicroRNA-21 in scleroderma fibrosis and its function in TGF-beta-regulated fibrosis-related genes expression
    • 1:CAS:528:DC%2BC3sXhtV2rsr3P 23657402
    • Zhu H, Luo H, Li Y, Zhou Y, Jiang Y, Chai J et al (2013) MicroRNA-21 in scleroderma fibrosis and its function in TGF-beta-regulated fibrosis-related genes expression. J Clin Immunol 33:1100-1109
    • (2013) J Clin Immunol , vol.33 , pp. 1100-1109
    • Zhu, H.1    Luo, H.2    Li, Y.3    Zhou, Y.4    Jiang, Y.5    Chai, J.6
  • 125
    • 77649243539 scopus 로고    scopus 로고
    • MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells
    • 2840357 1:CAS:528:DC%2BC3cXis1CgtbY%3D 20133739
    • Qin X, Wang X, Wang Y, Tang Z, Cui Q, Xi J et al (2010) MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells. Proc Natl Acad Sci USA 107:3240-3244
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3240-3244
    • Qin, X.1    Wang, X.2    Wang, Y.3    Tang, Z.4    Cui, Q.5    Xi, J.6
  • 126
    • 84865322922 scopus 로고    scopus 로고
    • MicroRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma
    • 1:CAS:528:DC%2BC38Xht1Gjt7vM 22661558
    • Sing T, Jinnin M, Yamane K, Honda N, Makino K, Kajihara I et al (2012) microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma. Rheumatology 51:1550-1556
    • (2012) Rheumatology , vol.51 , pp. 1550-1556
    • Sing, T.1    Jinnin, M.2    Yamane, K.3    Honda, N.4    Makino, K.5    Kajihara, I.6
  • 128
    • 84868014002 scopus 로고    scopus 로고
    • The role of microRNA-146a in the pathogenesis of the diabetic wound-healing impairment: Correction with mesenchymal stem cell treatment
    • 3478555 1:CAS:528:DC%2BC38Xhsl2it7vK 22851573
    • Xu J, Wu W, Zhang L, Dorset-Martin W, Morris MW, Mitchell ME et al (2012) The role of microRNA-146a in the pathogenesis of the diabetic wound-healing impairment: correction with mesenchymal stem cell treatment. Diabetes 61:2906-2912
    • (2012) Diabetes , vol.61 , pp. 2906-2912
    • Xu, J.1    Wu, W.2    Zhang, L.3    Dorset-Martin, W.4    Morris, M.W.5    Mitchell, M.E.6
  • 129
    • 72049114407 scopus 로고    scopus 로고
    • Understanding melanoma signaling networks as the basis for molecular targeted therapy
    • 1:CAS:528:DC%2BD1MXhsFGmsLvL 19571822
    • Smalley KS (2010) Understanding melanoma signaling networks as the basis for molecular targeted therapy. J Invest Dermatol 130:28-37
    • (2010) J Invest Dermatol , vol.130 , pp. 28-37
    • Smalley, K.S.1
  • 130
    • 0037364096 scopus 로고    scopus 로고
    • Pathophysiological implications of stroma pattern formation in uveal melanoma
    • 1:CAS:528:DC%2BD3sXhtFKiurk%3D 12548547
    • Clarijs R, Ruiter DJ, De Waal RM (2003) Pathophysiological implications of stroma pattern formation in uveal melanoma. J Cell Physiol 194:267-271
    • (2003) J Cell Physiol , vol.194 , pp. 267-271
    • Clarijs, R.1    Ruiter, D.J.2    De Waal, R.M.3
  • 132
    • 0036163492 scopus 로고    scopus 로고
    • Melanoma-stroma interactions: Structural and functional aspects
    • 1:CAS:528:DC%2BD38Xhtleitb8%3D 11905603
    • Ruiter D, Bogenrieder T, Elder D, Herlyn M (2002) Melanoma-stroma interactions: structural and functional aspects. Lancet Oncol 3:35-43
    • (2002) Lancet Oncol , vol.3 , pp. 35-43
    • Ruiter, D.1    Bogenrieder, T.2    Elder, D.3    Herlyn, M.4
  • 133
    • 84863108845 scopus 로고    scopus 로고
    • MicroRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells
    • 1:CAS:528:DC%2BC38XhtlantL3I 22716245
    • Satzger I, Mattern A, Kuettler U, Weinspach D, Niebuhr M, Kapp A et al (2012) microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells. Exp Dermatol 21:509-514
    • (2012) Exp Dermatol , vol.21 , pp. 509-514
    • Satzger, I.1    Mattern, A.2    Kuettler, U.3    Weinspach, D.4    Niebuhr, M.5    Kapp, A.6
  • 134
    • 84876684076 scopus 로고    scopus 로고
    • Plasma microRNA-21 is associated with tumor burden in cutaneous melanoma
    • 1:CAS:528:DC%2BC3sXltVaiug%3D%3D 23303460
    • Saldanha G, Potter L, Shendge P, Osborne J, Nicholson S, Yii N et al (2013) Plasma microRNA-21 is associated with tumor burden in cutaneous melanoma. J Invest Dermatol 133:1381-1384
    • (2013) J Invest Dermatol , vol.133 , pp. 1381-1384
    • Saldanha, G.1    Potter, L.2    Shendge, P.3    Osborne, J.4    Nicholson, S.5    Yii, N.6
  • 135
    • 77952838399 scopus 로고    scopus 로고
    • Signatures of microRNAs and selected microRNA target genes in human melanoma
    • 1:CAS:528:DC%2BC3cXlvFyqsLc%3D 20442294
    • Philippidou D, Schmitt M, Moser D, Margue C, Nazarov PV, Muller A et al (2010) Signatures of microRNAs and selected microRNA target genes in human melanoma. Cancer Res 70:4163-4173
    • (2010) Cancer Res , vol.70 , pp. 4163-4173
    • Philippidou, D.1    Schmitt, M.2    Moser, D.3    Margue, C.4    Nazarov, P.V.5    Muller, A.6
  • 136
    • 84883420810 scopus 로고    scopus 로고
    • In-depth characterization of microRNA transcriptome in melanoma
    • 3762816 1:CAS:528:DC%2BC3sXhsVGisLbM 24023765
    • Kozubek J, Ma Z, Fleming E, Duggan T, Wu R, Shin DG et al (2013) In-depth characterization of microRNA transcriptome in melanoma. PLoS One 8:e72699
    • (2013) PLoS One , vol.8 , pp. 72699
    • Kozubek, J.1    Ma, Z.2    Fleming, E.3    Duggan, T.4    Wu, R.5    Shin, D.G.6
  • 137
    • 77956539987 scopus 로고    scopus 로고
    • Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3beta
    • 2937966 1:CAS:528:DC%2BC3cXhtFCns7nK 20525681
    • Mohamed JS, Lopez MA, Boriek AM (2010) Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3beta. J Biol Chem 285:29336-29347
    • (2010) J Biol Chem , vol.285 , pp. 29336-29347
    • Mohamed, J.S.1    Lopez, M.A.2    Boriek, A.M.3
  • 138
    • 84876530141 scopus 로고    scopus 로고
    • MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD)
    • 3898712 1:CAS:528:DC%2BC38Xhslekt7rJ 23190898
    • Reuland SN, Smith SM, Bemis LT, Goldstein NB, Almeida AR, Partyka KA et al (2013) MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD). J Invest Dermatol 133:1286-1293
    • (2013) J Invest Dermatol , vol.133 , pp. 1286-1293
    • Reuland, S.N.1    Smith, S.M.2    Bemis, L.T.3    Goldstein, N.B.4    Almeida, A.R.5    Partyka, K.A.6
  • 139
    • 84855906694 scopus 로고    scopus 로고
    • Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D
    • 1:CAS:528:DC%2BC38Xos1Kksw%3D%3D 22102694
    • Heinemann A, Zhao F, Pechlivanis S, Eberle J, Steinle A, Diederichs S et al (2012) Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D. Cancer Res 72:460-471
    • (2012) Cancer Res , vol.72 , pp. 460-471
    • Heinemann, A.1    Zhao, F.2    Pechlivanis, S.3    Eberle, J.4    Steinle, A.5    Diederichs, S.6
  • 140
    • 84901236372 scopus 로고    scopus 로고
    • MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar Fibroblasts
    • 4016251 24817011
    • Zhu HY, Li C, Bai WD, Su LL, Liu JQ, Li Y et al (2014) MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar Fibroblasts. PLoS One 9:e97114
    • (2014) PLoS One , vol.9 , pp. 97114
    • Zhu, H.Y.1    Li, C.2    Bai, W.D.3    Su, L.L.4    Liu, J.Q.5    Li, Y.6
  • 142
    • 84858397752 scopus 로고    scopus 로고
    • MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis
    • 1:CAS:528:DC%2BC38XntFOhu7g%3D 22417311
    • Meisgen F, Xu N, Wei T, Janson PC, Obad S, Broom O et al (2012) MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. Exp Dermatol 21:312-314
    • (2012) Exp Dermatol , vol.21 , pp. 312-314
    • Meisgen, F.1    Xu, N.2    Wei, T.3    Janson, P.C.4    Obad, S.5    Broom, O.6
  • 143
    • 80053159711 scopus 로고    scopus 로고
    • Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome
    • 3177648 1:CAS:528:DC%2BC3MXht1ajtbjI 21807764
    • Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A et al (2011) Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Hum Mol Genet 20:4025-4040
    • (2011) Hum Mol Genet , vol.20 , pp. 4025-4040
    • Joyce, C.E.1    Zhou, X.2    Xia, J.3    Ryan, C.4    Thrash, B.5    Menter, A.6
  • 144
    • 81255205360 scopus 로고    scopus 로고
    • Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis
    • 1:CAS:528:DC%2BC3MXhsFSktLnF 22094257
    • Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q et al (2011) Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell 20:635-648
    • (2011) Cancer Cell , vol.20 , pp. 635-648
    • Darido, C.1    Georgy, S.R.2    Wilanowski, T.3    Dworkin, S.4    Auden, A.5    Zhao, Q.6
  • 145
    • 84884211489 scopus 로고    scopus 로고
    • The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: Modulation of the miR-21 target MSH2 by RNA-binding protein DND1
    • 4026359 1:CAS:528:DC%2BC38Xnt1CltrY%3D 22614019
    • Bhandari A, Gordon W, Dizon D, Hopkin AS, Gordon E, Yu Z et al (2013) The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1. Oncogene 32:1497-1507
    • (2013) Oncogene , vol.32 , pp. 1497-1507
    • Bhandari, A.1    Gordon, W.2    Dizon, D.3    Hopkin, A.S.4    Gordon, E.5    Yu, Z.6
  • 146
    • 77649240980 scopus 로고    scopus 로고
    • Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth
    • 2840325 1:CAS:528:DC%2BC3cXis1Cgtbk%3D 20133741
    • Wang KC, Garmire LX, Young A, Nguyen P, Trinh A, Subramaniam S et al (2010) Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth. Proc Natl Acad Sci USA 107:3234-3239
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3234-3239
    • Wang, K.C.1    Garmire, L.X.2    Young, A.3    Nguyen, P.4    Trinh, A.5    Subramaniam, S.6
  • 147
    • 84896736329 scopus 로고    scopus 로고
    • UVA and UVB irradiation differentially regulate microRNA expression in human primary keratinocytes
    • 3877020 24391759
    • Kraemer A, Chen IP, Henning S, Faust A, Volkmer B, Atkinson MJ et al (2013) UVA and UVB irradiation differentially regulate microRNA expression in human primary keratinocytes. PLoS One 8:e83392
    • (2013) PLoS One , vol.8 , pp. 83392
    • Kraemer, A.1    Chen, I.P.2    Henning, S.3    Faust, A.4    Volkmer, B.5    Atkinson, M.J.6
  • 148
    • 78650276433 scopus 로고    scopus 로고
    • A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo
    • 1:CAS:528:DC%2BC3cXhsFGrsbzK 20827281
    • Hildebrand J, Rutze M, Walz N, Gallinat S, Wenck H, Deppert W et al (2011) A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo. J Invest Dermatol 131:20-29
    • (2011) J Invest Dermatol , vol.131 , pp. 20-29
    • Hildebrand, J.1    Rutze, M.2    Walz, N.3    Gallinat, S.4    Wenck, H.5    Deppert, W.6
  • 149
    • 79951782373 scopus 로고    scopus 로고
    • MicroRNA-24 regulates the processing of latent TGFbeta1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN
    • 3152464 1:CAS:528:DC%2BC3MXit1eht7g%3D 20945401
    • Luna C, Li G, Qiu J, Epstein DL, Gonzalez P (2011) MicroRNA-24 regulates the processing of latent TGFbeta1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN. J Cell Physiol 226:1407-1414
    • (2011) J Cell Physiol , vol.226 , pp. 1407-1414
    • Luna, C.1    Li, G.2    Qiu, J.3    Epstein, D.L.4    Gonzalez, P.5
  • 150
    • 84869112150 scopus 로고    scopus 로고
    • MiR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration
    • 3471232 1:CAS:528:DC%2BC38XhsFKmtrjI 23071155
    • Amelio I, Lena AM, Viticchie G, Shalom-Feuerstein R, Terrinoni A, Dinsdale D et al (2012) miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. J Cell Biol 199:347-363
    • (2012) J Cell Biol , vol.199 , pp. 347-363
    • Amelio, I.1    Lena, A.M.2    Viticchie, G.3    Shalom-Feuerstein, R.4    Terrinoni, A.5    Dinsdale, D.6
  • 151
    • 84893768139 scopus 로고    scopus 로고
    • Protein and miRNA profiling of radiation-induced skin injury in rats: The protective role of peroxiredoxin-6 against ionizing radiation
    • 1:CAS:528:DC%2BC2cXksVWrtbk%3D 24447893
    • Zhang S, Wang W, Gu Q, Xue J, Cao H, Tang Y et al (2014) Protein and miRNA profiling of radiation-induced skin injury in rats: the protective role of peroxiredoxin-6 against ionizing radiation. Free Radic Biol Med 69:96-107
    • (2014) Free Radic Biol Med , vol.69 , pp. 96-107
    • Zhang, S.1    Wang, W.2    Gu, Q.3    Xue, J.4    Cao, H.5    Tang, Y.6
  • 152
    • 84899524419 scopus 로고    scopus 로고
    • Altered miRNA expression profiles are involved in the protective effects of troxerutin against ultraviolet B radiation in normal human dermal fibroblasts
    • 1:CAS:528:DC%2BC2cXptFynsL0%3D 24504083
    • Cha HJ, Lee KS, Lee GT, Lee KK, Hong JT, Lee SN et al (2014) Altered miRNA expression profiles are involved in the protective effects of troxerutin against ultraviolet B radiation in normal human dermal fibroblasts. Int J Mol Med 33:957-963
    • (2014) Int J Mol Med , vol.33 , pp. 957-963
    • Cha, H.J.1    Lee, K.S.2    Lee, G.T.3    Lee, K.K.4    Hong, J.T.5    Lee, S.N.6
  • 153
    • 84872353504 scopus 로고    scopus 로고
    • Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases, and benign melanocytic nevi
    • 1:CAS:528:DC%2BC3sXlt1Cmtg%3D%3D 23111773
    • Sand M, Skrygan M, Sand D, Georgas D, Gambichler T, Hahn SA et al (2013) Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases, and benign melanocytic nevi. Cell Tissue Res 351:85-98
    • (2013) Cell Tissue Res , vol.351 , pp. 85-98
    • Sand, M.1    Skrygan, M.2    Sand, D.3    Georgas, D.4    Gambichler, T.5    Hahn, S.A.6
  • 154
    • 84876557026 scopus 로고    scopus 로고
    • MicroRNAs as an emerging target for melanoma therapy
    • 1:CAS:528:DC%2BC3sXlvF2jt70%3D 23594536
    • Ryu B, Hwang S, Alani RM (2013) MicroRNAs as an emerging target for melanoma therapy. J Invest Dermatol 133:1137-1139
    • (2013) J Invest Dermatol , vol.133 , pp. 1137-1139
    • Ryu, B.1    Hwang, S.2    Alani, R.M.3
  • 155
    • 84868592288 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma
    • 1:CAS:528:DC%2BC38XhsVemt7bI 23026055
    • Sand M, Skrygan M, Georgas D, Sand D, Hahn SA, Gambichler T et al (2012) Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma. J Dermatol Sci 68:119-126
    • (2012) J Dermatol Sci , vol.68 , pp. 119-126
    • Sand, M.1    Skrygan, M.2    Georgas, D.3    Sand, D.4    Hahn, S.A.5    Gambichler, T.6
  • 156
    • 84904758082 scopus 로고    scopus 로고
    • MicroRNA-34a targets Forkhead box j2 to modulate differentiation of endothelial progenitor cells in response to shear stress
    • Cheng BB, Qu MJ, Wu LL, Shen Y, Yan ZQ, Zhang P et al (2014) MicroRNA-34a targets Forkhead box j2 to modulate differentiation of endothelial progenitor cells in response to shear stress. J Mol Cell Cardiol 74C:4-12
    • (2014) J Mol Cell Cardiol , vol.74 , pp. 4-12
    • Cheng, B.B.1    Qu, M.J.2    Wu, L.L.3    Shen, Y.4    Yan, Z.Q.5    Zhang, P.6
  • 157
    • 84899943311 scopus 로고    scopus 로고
    • SIRT1 inhibition restores apoptotic sensitivity in p53-mutated human keratinocytes
    • 1:CAS:528:DC%2BC2cXmvVWrtrk%3D 24726431
    • Herbert KJ, Cook AL, Snow ET (2014) SIRT1 inhibition restores apoptotic sensitivity in p53-mutated human keratinocytes. Toxicol Appl Pharmacol 277:288-297
    • (2014) Toxicol Appl Pharmacol , vol.277 , pp. 288-297
    • Herbert, K.J.1    Cook, A.L.2    Snow, E.T.3
  • 158
    • 84882451168 scopus 로고    scopus 로고
    • A miR-34a-SIRT6 axis in the squamous cell differentiation network
    • 3746195 1:CAS:528:DC%2BC3sXhtFSqt7nL 23860128
    • Lefort K, Brooks Y, Ostano P, Cario-Andre M, Calpini V, Guinea-Viniegra J et al (2013) A miR-34a-SIRT6 axis in the squamous cell differentiation network. EMBO J 32:2248-2263
    • (2013) EMBO J , vol.32 , pp. 2248-2263
    • Lefort, K.1    Brooks, Y.2    Ostano, P.3    Cario-Andre, M.4    Calpini, V.5    Guinea-Viniegra, J.6
  • 159
    • 84892788295 scopus 로고    scopus 로고
    • MicroRNA expression patterns related to merkel cell polyomavirus infection in human merkel cell carcinoma
    • 3898110 1:CAS:528:DC%2BC3sXhsVOnt7vO 23962809
    • Xie H, Lee L, Caramuta S, Hoog A, Browaldh N, Bjornhagen V et al (2014) MicroRNA expression patterns related to merkel cell polyomavirus infection in human merkel cell carcinoma. J Invest Dermatol 134:507-517
    • (2014) J Invest Dermatol , vol.134 , pp. 507-517
    • Xie, H.1    Lee, L.2    Caramuta, S.3    Hoog, A.4    Browaldh, N.5    Bjornhagen, V.6
  • 160
    • 84864652312 scopus 로고    scopus 로고
    • Analysis of the miR-34a locus in 62 patients with familial cutaneous melanoma negative for CDKN2A/CDK4 screening
    • 1:CAS:528:DC%2BC38XotVKqt7o%3D 22198089
    • Cozzolino AM, Pedace L, Castori M, De Simone P, Preziosi N, Sperduti I et al (2012) Analysis of the miR-34a locus in 62 patients with familial cutaneous melanoma negative for CDKN2A/CDK4 screening. Fam Cancer 11:201-208
    • (2012) Fam Cancer , vol.11 , pp. 201-208
    • Cozzolino, A.M.1    Pedace, L.2    Castori, M.3    De Simone, P.4    Preziosi, N.5    Sperduti, I.6
  • 161
    • 77951093434 scopus 로고    scopus 로고
    • Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells
    • 1:CAS:528:DC%2BC3cXkvVSrtLk%3D 20090763
    • Antonini D, Russo MT, De Rosa L, Gorrese M, Del Vecchio L, Missero C (2010) Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells. J Invest Dermatol 130:1249-1257
    • (2010) J Invest Dermatol , vol.130 , pp. 1249-1257
    • Antonini, D.1    Russo, M.T.2    De Rosa, L.3    Gorrese, M.4    Del Vecchio, L.5    Missero, C.6
  • 162
    • 84895869508 scopus 로고    scopus 로고
    • MicroRNA miR-17-92 cluster is highly expressed in epidermal Langerhans cells but not required for its development
    • 1:CAS:528:DC%2BC3sXhvVKgsb7M 24285176
    • Zhou L, Qi RQ, Liu M, Xu YP, Li G, Weiland M et al (2014) microRNA miR-17-92 cluster is highly expressed in epidermal Langerhans cells but not required for its development. Genes Immun 15:57-61
    • (2014) Genes Immun , vol.15 , pp. 57-61
    • Zhou, L.1    Qi, R.Q.2    Liu, M.3    Xu, Y.P.4    Li, G.5    Weiland, M.6
  • 165
    • 84877966077 scopus 로고    scopus 로고
    • Stretch-sensitive down-regulation of the miR-144/451 cluster in vascular smooth muscle and its role in AMP-activated protein kinase signaling
    • 3660603 23705032
    • Turczynska KM, Bhattachariya A, Sall J, Goransson O, Sward K, Hellstrand P et al (2013) Stretch-sensitive down-regulation of the miR-144/451 cluster in vascular smooth muscle and its role in AMP-activated protein kinase signaling. PLoS One 8:e65135
    • (2013) PLoS One , vol.8 , pp. 65135
    • Turczynska, K.M.1    Bhattachariya, A.2    Sall, J.3    Goransson, O.4    Sward, K.5    Hellstrand, P.6
  • 166
    • 84901374345 scopus 로고    scopus 로고
    • Mechanical stretch suppresses microRNA-145 expression by activating extracellular signal-regulated kinase 1/2 and upregulating angiotensin-converting enzyme to alter vascular smooth muscle cell phenotype
    • 4029552 24848371
    • Hu B, Song JT, Qu HY, Bi CL, Huang XZ, Liu XX et al (2014) Mechanical stretch suppresses microRNA-145 expression by activating extracellular signal-regulated kinase 1/2 and upregulating angiotensin-converting enzyme to alter vascular smooth muscle cell phenotype. PLoS One 9:e96338
    • (2014) PLoS One , vol.9 , pp. 96338
    • Hu, B.1    Song, J.T.2    Qu, H.Y.3    Bi, C.L.4    Huang, X.Z.5    Liu, X.X.6
  • 167
    • 84876351263 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates endothelial cell angiotensin-converting enzyme expression via p53 and the post-transcriptional regulation of microRNA-143/145
    • 1:CAS:528:DC%2BC3sXlslans7g%3D 23476055
    • Kohlstedt K, Trouvain C, Boettger T, Shi L, Fisslthaler B, Fleming I (2013) AMP-activated protein kinase regulates endothelial cell angiotensin-converting enzyme expression via p53 and the post-transcriptional regulation of microRNA-143/145. Circ Res 112:1150-1158
    • (2013) Circ Res , vol.112 , pp. 1150-1158
    • Kohlstedt, K.1    Trouvain, C.2    Boettger, T.3    Shi, L.4    Fisslthaler, B.5    Fleming, I.6
  • 168
    • 84857708170 scopus 로고    scopus 로고
    • Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
    • 1:CAS:528:DC%2BC38XitFalu7c%3D 22327366
    • Hergenreider E, Heydt S, Treguer K, Boettger T, Horrevoets AJ, Zeiher AM et al (2012) Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol 14:249-256
    • (2012) Nat Cell Biol , vol.14 , pp. 249-256
    • Hergenreider, E.1    Heydt, S.2    Treguer, K.3    Boettger, T.4    Horrevoets, A.J.5    Zeiher, A.M.6
  • 169
    • 84874639663 scopus 로고    scopus 로고
    • MiR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells
    • 1:CAS:528:DC%2BC3sXmt1emur0%3D 23404256
    • Dynoodt P, Speeckaert R, De Wever O, Chevolet I, Brochez L, Lambert J et al (2013) miR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells. Int J Oncol 42:1443-1451
    • (2013) Int J Oncol , vol.42 , pp. 1443-1451
    • Dynoodt, P.1    Speeckaert, R.2    De Wever, O.3    Chevolet, I.4    Brochez, L.5    Lambert, J.6
  • 170
    • 84872094747 scopus 로고    scopus 로고
    • The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma
    • 1:CAS:528:DC%2BC38XhvFSns7rF 23222547
    • Yamashita J, Iwakiri T, Fukushima S, Jinnin M, Miyashita A, Hamasaki T et al (2013) The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma. Melanoma Res 23:13-20
    • (2013) Melanoma Res , vol.23 , pp. 13-20
    • Yamashita, J.1    Iwakiri, T.2    Fukushima, S.3    Jinnin, M.4    Miyashita, A.5    Hamasaki, T.6
  • 171
    • 84869841704 scopus 로고    scopus 로고
    • Dysregulation of miRNA146a versus IRAK1 induces IL-17 persistence in the psoriatic skin lesions
    • 1:CAS:528:DC%2BC3sXkt1ajtQ%3D%3D 23018031
    • Xia P, Fang X, Zhang ZH, Huang Q, Yan KX, Kang KF et al (2012) Dysregulation of miRNA146a versus IRAK1 induces IL-17 persistence in the psoriatic skin lesions. Immunol Lett 148:151-162
    • (2012) Immunol Lett , vol.148 , pp. 151-162
    • Xia, P.1    Fang, X.2    Zhang, Z.H.3    Huang, Q.4    Yan, K.X.5    Kang, K.F.6
  • 172
    • 84899436770 scopus 로고    scopus 로고
    • RNASEL and MIR146A SNP-SNP interaction as a susceptibility factor for non-melanoma skin cancer
    • 3974770 24699816
    • Farzan SF, Karagas MR, Christensen BC, Li Z, Kuriger JK, Nelson HH et al (2014) RNASEL and MIR146A SNP-SNP interaction as a susceptibility factor for non-melanoma skin cancer. PLoS One 9:e93602
    • (2014) PLoS One , vol.9 , pp. 93602
    • Farzan, S.F.1    Karagas, M.R.2    Christensen, B.C.3    Li, Z.4    Kuriger, J.K.5    Nelson, H.H.6
  • 175
    • 84879398642 scopus 로고    scopus 로고
    • STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma
    • 3735708 1:CAS:528:DC%2BC2cXjsVGi 23676217
    • Kopp KL, Ralfkiaer U, Gjerdrum LM, Helvad R, Pedersen IH, Litman T et al (2013) STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma. Cell Cycle 12:1939-1947
    • (2013) Cell Cycle , vol.12 , pp. 1939-1947
    • Kopp, K.L.1    Ralfkiaer, U.2    Gjerdrum, L.M.3    Helvad, R.4    Pedersen, I.H.5    Litman, T.6
  • 178
    • 84863733598 scopus 로고    scopus 로고
    • Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides
    • 1:CAS:528:DC%2BC38XhtlKqtbfF 22776000
    • Benner MF, Ballabio E, van Kester MS, Saunders NJ, Vermeer MH, Willemze R et al (2012) Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides. Exp Dermatol 21:632-634
    • (2012) Exp Dermatol , vol.21 , pp. 632-634
    • Benner, M.F.1    Ballabio, E.2    Van Kester, M.S.3    Saunders, N.J.4    Vermeer, M.H.5    Willemze, R.6
  • 179
    • 80155124637 scopus 로고    scopus 로고
    • Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)
    • 3342856 1:CAS:528:DC%2BC3MXhs1ShtrbI 21865341
    • Ralfkiaer U, Hagedorn PH, Bangsgaard N, Lovendorf MB, Ahler CB, Svensson L et al (2011) Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL). Blood 118:5891-5900
    • (2011) Blood , vol.118 , pp. 5891-5900
    • Ralfkiaer, U.1    Hagedorn, P.H.2    Bangsgaard, N.3    Lovendorf, M.B.4    Ahler, C.B.5    Svensson, L.6
  • 180
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • 1:CAS:528:DC%2BD1cXltl2is7c%3D 18376396
    • Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G et al (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10:593-601
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3    Barry, S.C.4    Tsykin, A.5    Farshid, G.6
  • 181
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • 2279201 1:CAS:528:DC%2BD1cXksVGktL4%3D 18381893
    • Park SM, Gaur AB, Lengyel E, Peter ME (2008) The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22:894-907
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 182
    • 78650305974 scopus 로고    scopus 로고
    • MiR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness
    • 1:STN:280:DC%2BC3M%2FivFGmtg%3D%3D 20818426
    • Gotte M, Mohr C, Koo CY, Stock C, Vaske AK, Viola M et al (2010) miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness. Oncogene 29:6569-6580
    • (2010) Oncogene , vol.29 , pp. 6569-6580
    • Gotte, M.1    Mohr, C.2    Koo, C.Y.3    Stock, C.4    Vaske, A.K.5    Viola, M.6
  • 183
    • 62549148270 scopus 로고    scopus 로고
    • P53 represses c-Myc through induction of the tumor suppressor miR-145
    • 2651330 1:CAS:528:DC%2BD1MXivF2jsrg%3D 19202062
    • Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S et al (2009) p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 106:3207-3212
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3    Wu, H.4    Walia, V.5    Kumar, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.