-
1
-
-
33847279025
-
Pathogenesis and therapy of psoriasis
-
M. A. Lowes, A. M. Bowcock, J. G. Krueger, Pathogenesis and therapy of psoriasis. Nature 445, 866-873 (2007).
-
(2007)
Nature
, vol.445
, pp. 866-873
-
-
Lowes, M.A.1
Bowcock, A.M.2
Krueger, J.G.3
-
2
-
-
77951094127
-
Molecular dissection of psoriasis: Integrating genetics and biology
-
J. T. Elder, A. T. Bruce, J. E. Gudjonsson, A. Johnston, P. E. Stuart, T. Tejasvi, J. J. Voorhees, G. R. Abecasis, R. P. Nair, Molecular dissection of psoriasis: Integrating genetics and biology. J. Invest. Dermatol. 130, 1213-1226 (2010).
-
(2010)
J. Invest. Dermatol.
, vol.130
, pp. 1213-1226
-
-
Elder, J.T.1
Bruce, A.T.2
Gudjonsson, J.E.3
Johnston, A.4
Stuart, P.E.5
Tejasvi, T.6
Voorhees, J.J.7
Abecasis, G.R.8
Nair, R.P.9
-
3
-
-
84866085028
-
Current and emerging systemic treatment strategies for psoriasis
-
P. M. Laws, H. S. Young, Current and emerging systemic treatment strategies for psoriasis. Drugs 72, 1867-1880 (2012).
-
(2012)
Drugs
, vol.72
, pp. 1867-1880
-
-
Laws, P.M.1
Young, H.S.2
-
5
-
-
78649857725
-
Psoriasis: What we have learned from mouse models
-
E. F. Wagner, H. B. Schonthaler, J. Guinea-Viniegra, E. Tschachler, Psoriasis: What we have learned from mouse models. Nat. Rev. Rheumatol. 6, 704-714 (2010).
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 704-714
-
-
Wagner, E.F.1
Schonthaler, H.B.2
Guinea-Viniegra, J.3
Tschachler, E.4
-
6
-
-
84875864504
-
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
-
M. A. Lowes, C. B. Russell, D. A. Martin, J. E. Towne, J. G. Krueger, The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses. Trends Immunol. 34, 174-181 (2013).
-
(2013)
Trends Immunol.
, vol.34
, pp. 174-181
-
-
Lowes, M.A.1
Russell, C.B.2
Martin, D.A.3
Towne, J.E.4
Krueger, J.G.5
-
7
-
-
72749114289
-
TNFα shedding and epidermal inflammation are controlled by Jun proteins
-
J. Guinea-Viniegra, R. Zenz, H. Scheuch, D. Hnisz, M. Holcmann, L. Bakiri, H. B. Schonthaler, M. Sibilia, E. F. Wagner, TNFα shedding and epidermal inflammation are controlled by Jun proteins. Genes Dev. 23, 2663-2674 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2663-2674
-
-
Guinea-Viniegra, J.1
Zenz, R.2
Scheuch, H.3
Hnisz, D.4
Holcmann, M.5
Bakiri, L.6
Schonthaler, H.B.7
Sibilia, M.8
Wagner, E.F.9
-
8
-
-
77953138958
-
MicroRNAs and potential target interactions in psoriasis
-
J. R. Zibert, M. B. Løvendorf, T. Litman, J. Olsen, B. Kaczkowski, L. Skov, MicroRNAs and potential target interactions in psoriasis. J. Dermatol. Sci. 58, 177-185 (2010).
-
(2010)
J. Dermatol. Sci.
, vol.58
, pp. 177-185
-
-
Zibert, J.R.1
Løvendorf, M.B.2
Litman, T.3
Olsen, J.4
Kaczkowski, B.5
Skov, L.6
-
9
-
-
84863788258
-
Safety of anti-TNFα agents in the treatment of psoriasis and psoriatic arthritis
-
G. Girolomoni, G. Altomare, F. Ayala, E. Berardesca, P. Calzavara-Pinton, S. Chimenti, A. Peserico, A. Puglisi Guerra, G. A. Vena, Safety of anti-TNFα agents in the treatment of psoriasis and psoriatic arthritis. Immunopharmacol. Immunotoxicol. 34, 548-560 (2012).
-
(2012)
Immunopharmacol. Immunotoxicol.
, vol.34
, pp. 548-560
-
-
Girolomoni, G.1
Altomare, G.2
Ayala, F.3
Berardesca, E.4
Calzavara-Pinton, P.5
Chimenti, S.6
Peserico, A.7
Puglisi Guerra, A.8
Vena, G.A.9
-
10
-
-
81355142141
-
Non-coding RNAs in human disease
-
M. Esteller, Non-coding RNAs in human disease. Nat. Rev. Genet. 12, 861-874 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 861-874
-
-
Esteller, M.1
-
11
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
H. L. Janssen, H. W. Reesink, E. J. Lawitz, S. Zeuzem,M. Rodriguez-Torres, K. Patel, A. J. van derMeer, A. K. Patick, A. Chen, Y. Zhou, R. Persson, B. D. King, S. Kauppinen, A. A. Levin, M. R. Hodges, Treatment of HCV infection by targeting microRNA. N. Engl. J. Med. 368, 1685-1694 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
Van DerMeer, A.J.7
Patick, A.K.8
Chen, A.9
Zhou, Y.10
Persson, R.11
King, B.D.12
Kauppinen, S.13
Levin, A.A.14
Hodges, M.R.15
-
12
-
-
84856401413
-
microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris
-
A. Ichihara, M. Jinnin, K. Yamane, A. Fujisawa, K. Sakai, S. Masuguchi, S. Fukushima, K. Maruo, H. Ihn, microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris. Br. J. Dermatol. 165, 1003-1010 (2011).
-
(2011)
Br. J. Dermatol.
, vol.165
, pp. 1003-1010
-
-
Ichihara, A.1
Jinnin, M.2
Yamane, K.3
Fujisawa, A.4
Sakai, K.5
Masuguchi, S.6
Fukushima, S.7
Maruo, K.8
Ihn, H.9
-
13
-
-
80053159711
-
Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome
-
C. E. Joyce, X. Zhou, J. Xia, C. Ryan, B. Thrash, A. Menter, W. Zhang, A. M. Bowcock, Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Hum. Mol. Genet. 20, 4025-4040 (2011).
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4025-4040
-
-
Joyce, C.E.1
Zhou, X.2
Xia, J.3
Ryan, C.4
Thrash, B.5
Menter, A.6
Zhang, W.7
Bowcock, A.M.8
-
14
-
-
77951233965
-
MicroRNAs: Novel regulators involved in the pathogenesis of psoriasis?
-
E. Sonkoly, T. Wei, P. C. Janson, A. Sääf, L. Lundeberg, M. Tengvall-Linder, G. Norstedt, H. Alenius, B. Homey, A. Scheynius, M. Ståhle, A. Pivarcsi, MicroRNAs: Novel regulators involved in the pathogenesis of psoriasis? PLOS One 2, e610 (2007).
-
(2007)
PLOS One
, vol.2
-
-
Sonkoly, E.1
Wei, T.2
Janson, P.C.3
Sääf, A.4
Lundeberg, L.5
Tengvall-Linder, M.6
Norstedt, G.7
Alenius, H.8
Homey, B.9
Scheynius, A.10
Ståhle, M.11
Pivarcsi, A.12
-
15
-
-
84858397752
-
MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis
-
F. Meisgen, N. Xu, T. Wei, P. C. Janson, S. Obad, O. Broom, N. Nagy, S. Kauppinen, L. Kemény, M. Ståhle, A. Pivarcsi, E. Sonkoly, MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. Exp. Dermatol. 21, 312-314 (2012).
-
(2012)
Exp. Dermatol.
, vol.21
, pp. 312-314
-
-
Meisgen, F.1
Xu, N.2
Wei, T.3
Janson, P.C.4
Obad, S.5
Broom, O.6
Nagy, N.7
Kauppinen, S.8
Kemény, L.9
Ståhle, M.10
Pivarcsi, A.11
Sonkoly, E.12
-
16
-
-
84655167961
-
MicroRNAs as novel players in skin development, homeostasis and disease
-
M. R. Schneider, MicroRNAs as novel players in skin development, homeostasis and disease. Br. J. Dermatol. 166, 22-28 (2012).
-
(2012)
Br. J. Dermatol.
, vol.166
, pp. 22-28
-
-
Schneider, M.R.1
-
17
-
-
66149110971
-
MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3
-
F. M. Selaru, A. V. Olaru, T. Kan, S. David, Y. Cheng, Y. Mori, J. Yang, B. Paun, Z. Jin, R. Agarwal, J. P. Hamilton, J. Abraham, C. Georgiades, H. Alvarez, P. Vivekanandan, W. Yu, A. Maitra, M. Torbenson, P. J. Thuluvath, G. J. Gores, N. F. LaRusso, R. Hruban, S. J. Meltzer, MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3. Hepatology 49, 1595-1601 (2009).
-
(2009)
Hepatology
, vol.49
, pp. 1595-1601
-
-
Selaru, F.M.1
Olaru, A.V.2
Kan, T.3
David, S.4
Cheng, Y.5
Mori, Y.6
Yang, J.7
Paun, B.8
Jin, Z.9
Agarwal, R.10
Hamilton, J.P.11
Abraham, J.12
Georgiades, C.13
Alvarez, H.14
Vivekanandan, P.15
Yu, W.16
Maitra, A.17
Torbenson, M.18
Thuluvath, P.J.19
Gores, G.J.20
LaRusso, N.F.21
Hruban, R.22
Meltzer, S.J.23
more..
-
18
-
-
77950095763
-
TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
-
B. Wang, S. H. Hsu, S. Majumder, H. Kutay, W. Huang, S. T. Jacob, K. Ghoshal, TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene 29, 1787-1797 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 1787-1797
-
-
Wang, B.1
Hsu, S.H.2
Majumder, S.3
Kutay, H.4
Huang, W.5
Jacob, S.T.6
Ghoshal, K.7
-
19
-
-
75849142549
-
Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis
-
H. B. Schonthaler, R. Huggenberger, S. K. Wculek, M. Detmar, E. F. Wagner, Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis. Proc. Natl. Acad. Sci. U.S.A. 106, 21264-21269 (2009).
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 21264-21269
-
-
Schonthaler, H.B.1
Huggenberger, R.2
Wculek, S.K.3
Detmar, M.4
Wagner, E.F.5
-
20
-
-
25144497098
-
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
-
R. Zenz, R. Eferl, L. Kenner, L. Florin, L. Hummerich, D. Mehic, H. Scheuch, P. Angel, E. Tschachler, E. F. Wagner, Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature 437, 369-375 (2005).
-
(2005)
Nature
, vol.437
, pp. 369-375
-
-
Zenz, R.1
Eferl, R.2
Kenner, L.3
Florin, L.4
Hummerich, L.5
Mehic, D.6
Scheuch, H.7
Angel, P.8
Tschachler, E.9
Wagner, E.F.10
-
21
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
D. Iliopoulos, S. A. Jaeger, H. A. Hirsch, M. L. Bulyk, K. Struhl, STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol. Cell 39, 493-506 (2010).
-
(2010)
Mol. Cell
, vol.39
, pp. 493-506
-
-
Iliopoulos, D.1
Jaeger, S.A.2
Hirsch, H.A.3
Bulyk, M.L.4
Struhl, K.5
-
22
-
-
33645019429
-
Increased JunB mRNA and protein expression in psoriasis vulgaris lesions
-
A. S. Haider, J. Duculan, J. A. Whynot, J. G. Krueger, Increased JunB mRNA and protein expression in psoriasis vulgaris lesions. J. Invest. Dermatol. 126, 912-914 (2006).
-
(2006)
J. Invest. Dermatol.
, vol.126
, pp. 912-914
-
-
Haider, A.S.1
Duculan, J.2
Whynot, J.A.3
Krueger, J.G.4
-
23
-
-
79953202455
-
Silencing of microRNA families by seed-targeting tiny LNAs
-
S. Obad, C. O. dos Santos, A. Petri, M. Heidenblad, O. Broom, C. Ruse, C. Fu, M. Lindow, J. Stenvang, E. M. Straarup, H. F. Hansen, T. Koch, D. Pappin, G. J. Hannon, S. Kauppinen, Silencing of microRNA families by seed-targeting tiny LNAs. Nat. Genet. 43, 371-378 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 371-378
-
-
Obad, S.1
Dos Santos, C.O.2
Petri, A.3
Heidenblad, M.4
Broom, O.5
Ruse, C.6
Fu, C.7
Lindow, M.8
Stenvang, J.9
Straarup, E.M.10
Hansen, H.F.11
Koch, T.12
Pappin, D.13
Hannon, G.J.14
Kauppinen, S.15
-
24
-
-
79959918202
-
Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis
-
X. Ma, M. Kumar, S. N. Choudhury, L. E. Becker Buscaglia, J. R. Barker, K. Kanakamedala, M. F. Liu, Y. Li, Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis. Proc. Natl. Acad. Sci. U.S.A. 108, 10144-10149 (2011).
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 10144-10149
-
-
Ma, X.1
Kumar, M.2
Choudhury, S.N.3
Becker Buscaglia, L.E.4
Barker, J.R.5
Kanakamedala, K.6
Liu, M.F.7
Li, Y.8
-
25
-
-
0028959397
-
Severe combined immunodeficiency mouse and human psoriatic skin chimeras. Validation of a new animal model
-
B. J. Nickoloff, S. L. Kunkel, M. Burdick, R. M. Strieter, Severe combined immunodeficiency mouse and human psoriatic skin chimeras. Validation of a new animal model. Am. J. Pathol. 146, 580-588 (1995).
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 580-588
-
-
Nickoloff, B.J.1
Kunkel, S.L.2
Burdick, M.3
Strieter, R.M.4
-
26
-
-
0344926414
-
Etanercept as monotherapy in patients with psoriasis
-
Etanercept Psoriasis Study Group
-
C. L. Leonardi, J. L. Powers, R. T. Matheson, B. S. Goffe, R. Zitnik, A. Wang, A. B. Gottlieb; Etanercept Psoriasis Study Group, Etanercept as monotherapy in patients with psoriasis. N. Engl. J. Med. 349, 2014-2022 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2014-2022
-
-
Leonardi, C.L.1
Powers, J.L.2
Matheson, R.T.3
Goffe, B.S.4
Zitnik, R.5
Wang, A.6
Gottlieb, A.B.7
-
27
-
-
77955842799
-
Psoriasis genetics: Breaking the barrier
-
E. D. Roberson, A. M. Bowcock, Psoriasis genetics: Breaking the barrier. Trends Genet. 26, 415-423 (2010).
-
(2010)
Trends Genet.
, vol.26
, pp. 415-423
-
-
Roberson, E.D.1
Bowcock, A.M.2
-
28
-
-
80054048979
-
Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis
-
X. Gu, E. Nylander, P. J. Coates, K. Nylander, Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis. Acta Derm. Venereol. 91, 392-397 (2011).
-
(2011)
Acta Derm. Venereol.
, vol.91
, pp. 392-397
-
-
Gu, X.1
Nylander, E.2
Coates, P.J.3
Nylander, K.4
-
29
-
-
84875198313
-
Options and opportunities for clinical management and treatment of psoriasis
-
U. Agrawal, M. Gupta, D. Dube, S. P. Vyas, Options and opportunities for clinical management and treatment of psoriasis. Crit. Rev. Ther. Drug Carrier Syst. 30, 51-90 (2013).
-
(2013)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.30
, pp. 51-90
-
-
Agrawal, U.1
Gupta, M.2
Dube, D.3
Vyas, S.P.4
-
30
-
-
77956501846
-
Modulation of K-Ras-dependent lung tumorigenesis by microRNA-21
-
M. E. Hatley, D. M. Patrick, M. R. Garcia, J. A. Richardson, R. Bassel-Duby, E. van Rooij, E. N. Olson, Modulation of K-Ras-dependent lung tumorigenesis by microRNA-21. Cancer Cell 18, 282-293 (2010).
-
(2010)
Cancer Cell
, vol.18
, pp. 282-293
-
-
Hatley, M.E.1
Patrick, D.M.2
Garcia, M.R.3
Richardson, J.A.4
Bassel-Duby, R.5
Van Rooij, E.6
Olson, E.N.7
-
31
-
-
77956339881
-
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
-
P. P. Medina, M. Nolde, F. J. Slack, OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 467, 86-90 (2010).
-
(2010)
Nature
, vol.467
, pp. 86-90
-
-
Medina, P.P.1
Nolde, M.2
Slack, F.J.3
-
32
-
-
84877809247
-
Immunogenicity and autoimmunity during anti-TNF therapy
-
F. Atzeni, R. Talotta, F. Salaffi, A. Cassinotti, V. Varisco, M. Battellino, S. Ardizzone, F. Pace, P. Sarzi-Puttini, Immunogenicity and autoimmunity during anti-TNF therapy. Autoimmun. Rev. 12, 703-708 (2013).
-
(2013)
Autoimmun. Rev.
, vol.12
, pp. 703-708
-
-
Atzeni, F.1
Talotta, R.2
Salaffi, F.3
Cassinotti, A.4
Varisco, V.5
Battellino, M.6
Ardizzone, S.7
Pace, F.8
Sarzi-Puttini, P.9
|