MicroRNAs as novel players in skin development, homeostasis and disease

British Journal of Dermatology

Volumn 166, Issue 1, 2012, Pages 22-28

  Schneider, M R ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA4 INTEGRIN; DICER; MESSENGER RNA; MICRORNA; MICRORNA 125B; MICRORNA 203; MICRORNA 31; MICRORNA 34A; MICRORNA 34C; PROTEIN; PROTEIN DGCR8; UNCLASSIFIED DRUG;

ATOPIC DERMATITIS; BIOGENESIS; CELL DIFFERENTIATION; GENE DELIVERY SYSTEM; GENE EXPRESSION; HOMEOSTASIS; HUMAN; IN SITU HYBRIDIZATION; KERATINOCYTE; MELANOMA; MICROARRAY ANALYSIS; MOLECULAR CLONING; MORPHOGENESIS; NONHUMAN; NORTHERN BLOTTING; ORGANOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; REVIEW; SEZARY SYNDROME; SKIN; SKIN CARCINOGENESIS; SKIN DEVELOPMENT; SKIN DISEASE; SQUAMOUS CELL CARCINOMA; STEM CELL; TRANSCRIPTION REGULATION;

ANIMALS; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; MICE; MICRORNAS; SKIN; SKIN DISEASES;

EID: 84655167961     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2011.10568.x     Document Type: Review

References (68)

1. Ambros V,. The functions of animal microRNAs. Nature 2004; 431: 350-5. (Pubitemid 39265675)
2. Bartel DP,. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
3. Kim VN,. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 2005; 6: 376-85. (Pubitemid 40637855)
4. Lynam-Lennon N, Maher SG, Reynolds JV,. The roles of microRNA in cancer and apoptosis. Biol Rev Camb Philos Soc 2009; 84: 55-71.
5. Lewis BP, Burge CB, Bartel DP,. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20. (Pubitemid 40094598)
6. Friedman RC, Farh KK, Burge CB, et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009; 19: 92-105.
7. Selbach M, Schwanhausser B, Thierfelder N, et al. Widespread changes in protein synthesis induced by microRNAs. Nature 2008; 455: 58-63.
8. Baek D, Villen J, Shin C, et al. The impact of microRNAs on protein output. Nature 2008; 455: 64-71.
9. Kloosterman WP, Plasterk RH,. The diverse functions of microRNAs in animal development and disease. Dev Cell 2006; 11: 441-50. (Pubitemid 44430905)
10. Poy MN, Eliasson L, Krutzfeldt J, et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 2004; 432: 226-30. (Pubitemid 39545853)
11. Esau C, Kang X, Peralta E, et al. MicroRNA-143 regulates adipocyte differentiation. J Biol Chem 2004; 279: 52361-5. (Pubitemid 39656612)
12. Bernstein E, Kim SY, Carmell MA, et al. Dicer is essential for mouse development. Nat Genet 2003; 35: 215-17. (Pubitemid 37363172)
13. Wang Y, Medvid R, Melton C, et al. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 2007; 39: 380-5. (Pubitemid 46328490)
14. Yi R, Fuchs E,. MicroRNA-mediated control in the skin. Cell Death Differ 2010; 17: 229-35.
15. Schmidt-Ullrich R, Paus R,. Molecular principles of hair follicle induction and morphogenesis. Bioessays 2005; 27: 247-61. (Pubitemid 40476488)
16. Yi R, O'Carroll D, Pasolli HA, et al. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet 2006; 38: 356-62.
17. Andl T, Murchison EP, Liu F, et al. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol 2006; 16: 1041-9. (Pubitemid 43744365)
18. Yi R, Pasolli HA, Landthaler M, et al. DGCR8-dependent microRNA biogenesis is essential for skin development. Proc Natl Acad Sci USA 2009; 106: 498-502.
19. Aberdam D, Candi E, Knight RA, et al. miRNAs, 'stemness' and skin. Trends Biochem Sci 2008; 33: 583-91.
20. Yi R, Poy MN, Stoffel M, et al. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 2008; 452: 225-9. (Pubitemid 351380241)
21. Wienholds E, Kloosterman WP, Miska E, et al. MicroRNA expression in zebrafish embryonic development. Science 2005; 309: 310-11. (Pubitemid 40967869)
22. Wei T, Orfanidis K, Xu N, et al. The expression of microRNA-203 during human skin morphogenesis. Exp Dermatol 2010; 19: 854-6.
23. Lena AM, Shalom-Feuerstein R, Rivetti Di Val Cervo P, et al. miR-203 represses 'stemness' by repressing DeltaNp63. Cell Death Differ 2008; 15: 1187-95. (Pubitemid 351850972)
24. Sonkoly E, Wei T, Pavez Loriè E, et al. Protein kinase C-dependent upregulation of miR-203 induces the differentiation of human keratinocytes. J Invest Dermatol 2010; 130: 124-34.
25. Senoo M, Pinto F, Crum CP, et al. p63 is essential for the proliferative potential of stem cells in stratified epithelia. Cell 2007; 129: 523-36. (Pubitemid 46660965)
26. Antonini D, Russo MT, De Rosa L, et al. Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells. J Invest Dermatol 2010; 130: 1249-57.
27. Su X, Chakravarti D, Cho MS, et al. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature 2010; 467: 986-90.
28. Schneider MR, Schmidt-Ullrich R, Paus R,. The hair follicle as a dynamic miniorgan. Curr Biol 2009; 19: R132-42.
29. Mardaryev AN, Ahmed MI, Vlahov NV, et al. Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle. FASEB J 2010; 24: 3869-81.
30. Zhang L, Stokes N, Polak L, et al. Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell 2011; 8: 294-308.
31. Garbe C, Leiter U,. Melanoma epidemiology and trends. Clin Dermatol 2009; 27: 3-9.
32. Schultz J, Lorenz P, Gross G, et al. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res 2008; 18: 549-57. (Pubitemid 351630945)
33. Mueller DW, Rehli M, Bosserhoff AK, miRNA expression profiling in melanocytes and melanoma cell lines reveals miRNAs associated with formation and progression of malignant melanoma. J Invest Dermatol 2009; 129: 1740-51.
34. Segura MF, Hanniford D, Menendez S, et al. Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. Proc Natl Acad Sci USA 2009; 106: 1814-19.
35. Caramuta S, Egyhazi S, Rodolfo M, et al. MicroRNA expression profiles associated with mutational status and survival in malignant melanoma. J Invest Dermatol 2010; 130: 2062-70.
36. Chen J, Feilotter HE, Pare GC, et al. MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma. Am J Pathol 2010; 176: 2520-9.
37. Mueller DW, Bosserhoff AK,. Role of miRNAs in the progression of malignant melanoma. Br J Cancer 2009; 101: 551-6.
38. Mueller DW, Bosserhoff AK,. The evolving concept of 'melano-miRs'- microRNAs in melanomagenesis. Pigment Cell Melanoma Res 2010; 23: 620-6.
39. Philippidou D, Schmitt M, Moser D, et al. Signatures of microRNAs and selected microRNA target genes in human melanoma. Cancer Res 2010; 70: 4163-73.
40. Stark MS, Tyagi S, Nancarrow DJ, et al. Characterization of the melanoma miRNAome by deep sequencing. PLoS ONE 2010; 5: e9685.
41. Segura MF, Belitskaya-Levy I, Rose AE, et al. Melanoma microRNA signature predicts post-recurrence survival. Clin Cancer Res 2010; 16: 1577-86.
42. Leidinger P, Keller A, Borries A, et al. High-throughput miRNA profiling of human melanoma blood samples. BMC Cancer 2010; 10: 262.
43. Dziunycz P, Iotzova-Weiss G, Eloranta JJ, et al. Squamous cell carcinoma of the skin shows a distinct microRNA profile modulated by UV radiation. J Invest Dermatol 2010; 130: 2686-9.
44. van der Fits L, van Kester MS, Qin Y, et al. MicroRNA-21 expression in CD4+ T cells is regulated by STAT3 and is pathologically involved in Sézary syndrome. J Invest Dermatol 2011; 131: 762-8.
45. Lowes MA, Bowcock AM, Krueger JG,. Pathogenesis and therapy of psoriasis. Nature 2007; 445: 866-73.
46. Sonkoly E, Wei T, Janson PC, et al. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS ONE 2007; 2: e610.
47. Zibert JR, Lovendorf MB, Litman T, et al. MicroRNAs and potential target interactions in psoriasis. J Dermatol Sci 2010; 58: 177-85.
48. Xu N, Brodin P, Wei T, et al. MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. J Invest Dermatol 2011; 131: 1521-9.
49. Sonkoly E, Janson P, Majuri ML, et al. MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4. J Allergy Clin Immunol 2010; 126: 581-9.
50. Sonkoly E, Stahle M, Pivarcsi A,. MicroRNAs: novel regulators in skin inflammation. Clin Exp Dermatol 2008; 33: 312-15. (Pubitemid 351550660)
51. Banerjee J, Chan YC, Sen CK,. MicroRNAs in skin and wound healing. Physiol Genomics 2011; 43: 543-56.
52. Biswas S, Roy S, Banerjee J, et al. Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. Proc Natl Acad Sci USA 2010; 107: 6976-81.
53. Krutzfeldt J, Rajewsky N, Braich R, et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005; 438: 685-9.
54. Obad S, dos Santos CO, Petri A, et al. Silencing of microRNA families by seed-targeting tiny LNAs. Nat Genet 2011; 43: 371-8.
55. Pedersen IM, Cheng G, Wieland S, et al. Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 2007; 449: 919-22. (Pubitemid 47598616)
56. Whitehead KA, Langer R, Anderson DG,. Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov 2009; 8: 129-38.
57. Gondi CS, Rao JS,. Concepts in in vivo siRNA delivery for cancer therapy. J Cell Physiol 2009; 220: 285-91.
58. Inoue T, Sugimoto M, Sakurai T, et al. Modulation of scratching behavior by silencing an endogenous cyclooxygenase-1 gene in the skin through the administration of siRNA. J Gene Med 2007; 9: 994-1001. (Pubitemid 350104414)
59. Palliser D, Chowdhury D, Wang QY, et al. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature 2006; 439: 89-94. (Pubitemid 43053634)
60. Schneider MR, Paus R,. Sebocytes, multifaceted epithelial cells: lipid production and holocrine secretion. Int J Biochem Cell Biol 2010; 42: 181-5.
61. Candi E, Schmidt R, Melino G,. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 2005; 6: 328-40. (Pubitemid 40516899)
62. Braig S, Mueller DW, Rothhammer T, et al. MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma. Cell Mol Life Sci 2010; 67: 3535-48.
63. Mueller DW, Bosserhoff AK,. MicroRNA miR-196a controls melanoma-associated genes by regulating HOX-C8 expression. Int J Cancer 2011; 129: 1064-74.
64. Bemis LT, Chen R, Amato CM, et al. MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines. Cancer Res 2008; 68: 1362-8. (Pubitemid 351346843)
65. Satzger I, Mattern A, Kuettler U, et al. MicroRNA-15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanoma. Int J Cancer 2010; 126: 2553-62.
66. Muller DW, Bosserhoff AK,. Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma. Oncogene 2008; 27: 6698-706.
67. Felicetti F, Errico MC, Bottero L, et al. The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms. Cancer Res 2008; 68: 2745-54. (Pubitemid 351556272)
68. Glud M, Rossing M, Hother C, et al. Downregulation of miR-125b in metastatic cutaneous malignant melanoma. Melanoma Res 2010; 20: 479-84.