YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

FEBS Letters

Volumn 588, Issue 16, 2014, Pages 2663-2670

  Low, Boon Chuan ^a,b   Pan, Catherine Qiurong ^a   Shivashankar, G V ^a   Bershadsky, Alexander ^a,c   Sudol, Marius ^a   Sheetz, Michael ^a,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Hippo tumor suppressor; Mechanosensor; Mechanotransducer; Organ size; YAP TAZ

Indexed keywords

ACTIN; ANGIOMOTIN; CELL PROTEIN; HIPPO PROTEIN; LATS PROTEIN; MST PROTEIN; MYOSIN ADENOSINE TRIPHOSPHATASE; PROTEIN KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SCAFFOLD PROTEIN; SCRIBBLE PROTEIN; UNCLASSIFIED DRUG; YAP PROTEIN; YAZ PROTEIN; ZONULA OCCLUDENS PROTEIN;

ACTIN FILAMENT; BINDING AFFINITY; CELL CONTACT; CELL PROLIFERATION; CELL STIMULATION; CELL STRUCTURE; CONTACT INHIBITION; EXTRACELLULAR MATRIX; INTRACELLULAR SIGNALING; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; MUSCLE CONTRACTILITY; ORGAN GROWTH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTO ONCOGENE; REVIEW; SIGNAL TRANSDUCTION; TENSILE STRENGTH;

HIPPO TUMOR SUPPRESSOR; MECHANOSENSOR; MECHANOTRANSDUCER; ORGAN SIZE; YAP/TAZ;

ANIMALS; CELL PROLIFERATION; HUMANS; MECHANOTRANSDUCTION, CELLULAR; NEOPLASMS; NUCLEAR PROTEINS; ORGAN SIZE; TRANSCRIPTION FACTORS;

EID: 84905101429     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.04.012     Document Type: Review

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