-
1
-
-
79960997489
-
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
-
B. Zhao, K. Tumaneng, and K.L. Guan The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal Nat Cell Biol 13 2011 877 883
-
(2011)
Nat Cell Biol
, vol.13
, pp. 877-883
-
-
Zhao, B.1
Tumaneng, K.2
Guan, K.L.3
-
2
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
R.W. Justice, O. Zilian, D.F. Woods, M. Noll, and P.J. Bryant The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation Genes Dev 9 1995 534 546
-
(1995)
Genes Dev
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
3
-
-
77951837150
-
The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
-
B. Zhao, L. Li, Q. Lei, and K.L. Guan The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version Genes Dev 24 2010 862 874
-
(2010)
Genes Dev
, vol.24
, pp. 862-874
-
-
Zhao, B.1
Li, L.2
Lei, Q.3
Guan, K.L.4
-
4
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
S. Dupont, L. Morsut, M. Aragona, E. Enzo, S. Giulitti, M. Cordenonsi, F. Zanconato, J. Le Digabel, M. Forcato, S. Bicciato, N. Elvassore, and S. Piccolo Role of YAP/TAZ in mechanotransduction Nature 474 2011 179 183
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
Zanconato, F.7
Le Digabel, J.8
Forcato, M.9
Bicciato, S.10
Elvassore, N.11
Piccolo, S.12
-
5
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
D. Pan The hippo signaling pathway in development and cancer Dev Cell 19 2010 491 505
-
(2010)
Dev Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
6
-
-
53849087493
-
Expression of Yes-associated protein in common solid tumors
-
A.A. Steinhardt, M.F. Gayyed, A.P. Klein, J. Dong, A. Maitra, D. Pan, E.A. Montgomery, and R.A. Anders Expression of Yes-associated protein in common solid tumors Hum Pathol 39 2008 1582 1589
-
(2008)
Hum Pathol
, vol.39
, pp. 1582-1589
-
-
Steinhardt, A.A.1
Gayyed, M.F.2
Klein, A.P.3
Dong, J.4
Maitra, A.5
Pan, D.6
Montgomery, E.A.7
Anders, R.A.8
-
7
-
-
82455210238
-
Connective tissue growth factor autocrine in human hepatocellular carcinoma: Oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation
-
R. Urtasun, M.U. Latasa, M.I. Demartis, S. Balzani, S. Goni, O. Garcia-Irigoyen, M. Elizalde, M. Azcona, R.M. Pascale, F. Feo, P. Bioulac-Sage, C. Balabaud, J. Muntane, J. Prieto, C. Berasain, and M.A. Avila Connective tissue growth factor autocrine in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation Hepatology 54 2011 2149 2158
-
(2011)
Hepatology
, vol.54
, pp. 2149-2158
-
-
Urtasun, R.1
Latasa, M.U.2
Demartis, M.I.3
Balzani, S.4
Goni, S.5
Garcia-Irigoyen, O.6
Elizalde, M.7
Azcona, M.8
Pascale, R.M.9
Feo, F.10
Bioulac-Sage, P.11
Balabaud, C.12
Muntane, J.13
Prieto, J.14
Berasain, C.15
Avila, M.A.16
-
8
-
-
79952297528
-
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
-
H. Zhang, H.A. Pasolli, and E. Fuchs Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin Proc Natl Acad Sci U S A 108 2011 2270 2275
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2270-2275
-
-
Zhang, H.1
Pasolli, H.A.2
Fuchs, E.3
-
9
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
-
D. Lai, K.C. Ho, Y. Hao, and X. Yang Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF Cancer Res 71 2011 2728 2738
-
(2011)
Cancer Res
, vol.71
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
10
-
-
0042855012
-
The CCN family: A new stimulus package
-
D.R. Brigstock The CCN family: a new stimulus package J Endocrinol 178 2003 169 175
-
(2003)
J Endocrinol
, vol.178
, pp. 169-175
-
-
Brigstock, D.R.1
-
11
-
-
0037395573
-
Report on the second international workshop on the CCN family of genes
-
B. Perbal, D.R. Brigstock, and L.F. Lau Report on the second international workshop on the CCN family of genes Mol Pathol 56 2003 80 85
-
(2003)
Mol Pathol
, vol.56
, pp. 80-85
-
-
Perbal, B.1
Brigstock, D.R.2
Lau, L.F.3
-
12
-
-
59649107705
-
Functions and mechanisms of action of CCN matricellular proteins
-
C.C. Chen, and L.F. Lau Functions and mechanisms of action of CCN matricellular proteins Int J Biochem Cell Biol 41 2009 771 783
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 771-783
-
-
Chen, C.C.1
Lau, L.F.2
-
13
-
-
82455198983
-
Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
-
J.I. Jun, and L.F. Lau Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets Nat Rev Drug Discov 10 2011 945 963
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 945-963
-
-
Jun, J.I.1
Lau, L.F.2
-
14
-
-
0347915577
-
CCN proteins: Multifunctional signalling regulators
-
B. Perbal CCN proteins: multifunctional signalling regulators Lancet 363 2004 62 64
-
(2004)
Lancet
, vol.363
, pp. 62-64
-
-
Perbal, B.1
-
15
-
-
79957462240
-
Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1
-
M.R. Silvis, B.T. Kreger, W.H. Lien, O. Klezovitch, G.M. Rudakova, F.D. Camargo, D.M. Lantz, J.T. Seykora, and V. Vasioukhin Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 Sci Signal 4 2011 ra33
-
(2011)
Sci Signal
, vol.4
, pp. 33
-
-
Silvis, M.R.1
Kreger, B.T.2
Lien, W.H.3
Klezovitch, O.4
Rudakova, G.M.5
Camargo, F.D.6
Lantz, D.M.7
Seykora, J.T.8
Vasioukhin, V.9
-
16
-
-
79952298459
-
Yap1 acts downstream of alpha-catenin to control epidermal proliferation
-
K. Schlegelmilch, M. Mohseni, O. Kirak, J. Pruszak, J.R. Rodriguez, D. Zhou, B.T. Kreger, V. Vasioukhin, J. Avruch, T.R. Brummelkamp, and F.D. Camargo Yap1 acts downstream of alpha-catenin to control epidermal proliferation Cell 144 2011 782 795
-
(2011)
Cell
, vol.144
, pp. 782-795
-
-
Schlegelmilch, K.1
Mohseni, M.2
Kirak, O.3
Pruszak, J.4
Rodriguez, J.R.5
Zhou, D.6
Kreger, B.T.7
Vasioukhin, V.8
Avruch, J.9
Brummelkamp, T.R.10
Camargo, F.D.11
-
17
-
-
0036121025
-
Connective tissue growth factor: Expression in human skin in vivo and inhibition by ultraviolet irradiation
-
T. Quan, T. He, S. Kang, J.J. Voorhees, and G.J. Fisher Connective tissue growth factor: expression in human skin in vivo and inhibition by ultraviolet irradiation J Invest Dermatol 118 2002 402 408
-
(2002)
J Invest Dermatol
, vol.118
, pp. 402-408
-
-
Quan, T.1
He, T.2
Kang, S.3
Voorhees, J.J.4
Fisher, G.J.5
-
18
-
-
0036038264
-
Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo
-
T. Quan, T. He, S. Kang, J.J. Voorhees, and G.J. Fisher Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo J Invest Dermatol 119 2002 499 506
-
(2002)
J Invest Dermatol
, vol.119
, pp. 499-506
-
-
Quan, T.1
He, T.2
Kang, S.3
Voorhees, J.J.4
Fisher, G.J.5
-
19
-
-
84876894055
-
CCN1 Domain-specific Stimulation of Matrix Metalloproteinase-1 Expression Through alphaVbeta3 Integrin in Human Skin Fibroblasts
-
Z. Qin, G.J. Fisher, and T. Quan CCN1 Domain-specific Stimulation of Matrix Metalloproteinase-1 Expression Through alphaVbeta3 Integrin in Human Skin Fibroblasts J Biol Chem 288 2013 12386 12394
-
(2013)
J Biol Chem
, vol.288
, pp. 12386-12394
-
-
Qin, Z.1
Fisher, G.J.2
Quan, T.3
-
20
-
-
0030695138
-
Pathophysiology of premature skin aging induced by ultraviolet light
-
G.J. Fisher, Z.Q. Wang, S.C. Datta, J. Varani, S. Kang, and J.J. Voorhees Pathophysiology of premature skin aging induced by ultraviolet light N Engl J Med 337 1997 1419 1428
-
(1997)
N Engl J Med
, vol.337
, pp. 1419-1428
-
-
Fisher, G.J.1
Wang, Z.Q.2
Datta, S.C.3
Varani, J.4
Kang, S.5
Voorhees, J.J.6
-
21
-
-
0025852002
-
Cellular, immunologic and biochemical characterization of topical retinoic acid-treated human skin
-
G.J. Fisher, J. Esmann, C.E. Griffiths, H.S. Talwar, E.A. Duell, C. Hammerberg, J.T. Elder, L.J. Finkel, G.D. Karabin, B.J. Nickoloff, K.D. Cooper, and J.J. Voorhees Cellular, immunologic and biochemical characterization of topical retinoic acid-treated human skin J Invest Dermatol 96 1991 699 707
-
(1991)
J Invest Dermatol
, vol.96
, pp. 699-707
-
-
Fisher, G.J.1
Esmann, J.2
Griffiths, C.E.3
Talwar, H.S.4
Duell, E.A.5
Hammerberg, C.6
Elder, J.T.7
Finkel, L.J.8
Karabin, G.D.9
Nickoloff, B.J.10
Cooper, K.D.11
Voorhees, J.J.12
-
22
-
-
33746607262
-
Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin
-
T. Quan, T. He, Y. Shao, L. Lin, S. Kang, J.J. Voorhees, and G.J. Fisher Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin Am J Pathol 169 2006 482 490
-
(2006)
Am J Pathol
, vol.169
, pp. 482-490
-
-
Quan, T.1
He, T.2
Shao, Y.3
Lin, L.4
Kang, S.5
Voorhees, J.J.6
Fisher, G.J.7
-
23
-
-
77952421301
-
Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts
-
T. Quan, Z. Qin, Y. Xu, T. He, S. Kang, J.J. Voorhees, and G.J. Fisher Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts J Invest Dermatol 130 2010 1697 1706
-
(2010)
J Invest Dermatol
, vol.130
, pp. 1697-1706
-
-
Quan, T.1
Qin, Z.2
Xu, Y.3
He, T.4
Kang, S.5
Voorhees, J.J.6
Fisher, G.J.7
-
24
-
-
84873727210
-
Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo
-
T. Quan, F. Wang, Y. Shao, L. Rittie, W. Xia, J.S. Orringer, J.J. Voorhees, and G.J. Fisher Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo J Invest Dermatol 133 2012 658 667
-
(2012)
J Invest Dermatol
, vol.133
, pp. 658-667
-
-
Quan, T.1
Wang, F.2
Shao, Y.3
Rittie, L.4
Xia, W.5
Orringer, J.S.6
Voorhees, J.J.7
Fisher, G.J.8
-
25
-
-
75549086340
-
Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin
-
T. Quan, Y. Shao, T. He, J.J. Voorhees, and G.J. Fisher Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin J Invest Dermatol 130 2010 415 424
-
(2010)
J Invest Dermatol
, vol.130
, pp. 415-424
-
-
Quan, T.1
Shao, Y.2
He, T.3
Voorhees, J.J.4
Fisher, G.J.5
-
26
-
-
48749112311
-
Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-beta-induced mouse fibrosis
-
Y. Ikawa, P.S. Ng, K. Endo, M. Kondo, S. Chujo, W. Ishida, F. Shirasaki, M. Fujimoto, and K. Takehara Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-beta-induced mouse fibrosis J Cell Physiol 216 2008 680 687
-
(2008)
J Cell Physiol
, vol.216
, pp. 680-687
-
-
Ikawa, Y.1
Ng, P.S.2
Endo, K.3
Kondo, M.4
Chujo, S.5
Ishida, W.6
Shirasaki, F.7
Fujimoto, M.8
Takehara, K.9
-
27
-
-
0031225015
-
Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
-
G.R. Grotendorst Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts Cytokine Growth Factor Rev 8 1997 171 179
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 171-179
-
-
Grotendorst, G.R.1
-
28
-
-
0036064618
-
Scleroderma and Smads: Dysfunctional Smad family dynamics culminating in fibrosis
-
J. Varga Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis Arthritis Rheum 46 2002 1703 1713
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1703-1713
-
-
Varga, J.1
-
29
-
-
0031713433
-
Extracellular matrix signaling: Integration of form and function in normal and malignant cells
-
N. Boudreau, and M.J. Bissell Extracellular matrix signaling: integration of form and function in normal and malignant cells Curr Opin Cell Biol 10 1998 640 646
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 640-646
-
-
Boudreau, N.1
Bissell, M.J.2
-
30
-
-
46049115251
-
Growth control by intracellular tension and extracellular stiffness
-
R.K. Assoian, and E.A. Klein Growth control by intracellular tension and extracellular stiffness Trends Cell Biol 18 2008 347 352
-
(2008)
Trends Cell Biol
, vol.18
, pp. 347-352
-
-
Assoian, R.K.1
Klein, E.A.2
-
31
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
M.J. Paszek, N. Zahir, K.R. Johnson, J.N. Lakins, G.I. Rozenberg, A. Gefen, C.A. Reinhart-King, S.S. Margulies, M. Dembo, D. Boettiger, D.A. Hammer, and V.M. Weaver Tensional homeostasis and the malignant phenotype Cancer Cell 8 2005 241 254
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
Zahir, N.2
Johnson, K.R.3
Lakins, J.N.4
Rozenberg, G.I.5
Gefen, A.6
Reinhart-King, C.A.7
Margulies, S.S.8
Dembo, M.9
Boettiger, D.10
Hammer, D.A.11
Weaver, V.M.12
-
32
-
-
84855326431
-
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
-
B. Zhao, L. Li, L. Wang, C.Y. Wang, J. Yu, and K.L. Guan Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis Genes Dev 26 2012 54 68
-
(2012)
Genes Dev
, vol.26
, pp. 54-68
-
-
Zhao, B.1
Li, L.2
Wang, L.3
Wang, C.Y.4
Yu, J.5
Guan, K.L.6
-
33
-
-
84878615570
-
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
-
F. Calvo, N. Ege, A. Grande-Garcia, S. Hooper, R.P. Jenkins, S.I. Chaudhry, K. Harrington, P. Williamson, E. Moeendarbary, G. Charras, and E. Sahai Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts Nat Cell Biol 15 2013 637 646
-
(2013)
Nat Cell Biol
, vol.15
, pp. 637-646
-
-
Calvo, F.1
Ege, N.2
Grande-Garcia, A.3
Hooper, S.4
Jenkins, R.P.5
Chaudhry, S.I.6
Harrington, K.7
Williamson, P.8
Moeendarbary, E.9
Charras, G.10
Sahai, E.11
|