Expression of microRNAs in basal cell carcinoma

British Journal of Dermatology

Volumn 167, Issue 4, 2012, Pages 847-855

  Sand, M ^a   Skrygan, M ^a   Sand, D ^b   Georgas, D ^a   Hahn, S A ^a   Gambichler, T ^a   Altmeyer, P ^a   Bechara, F G ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b OLIVE VIEW UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 106B; MICRORNA 125A 5P; MICRORNA 130A; MICRORNA 139 5P; MICRORNA 140 3P; MICRORNA 145; MICRORNA 17; MICRORNA 181C; MICRORNA 181D; MICRORNA 182; MICRORNA 18A; MICRORNA 18B; MICRORNA 19B; MICRORNA 19B 1; MICRORNA 2861; MICRORNA 29C; MICRORNA 3196; MICRORNA 378; MICRORNA 455 3P; MICRORNA 455 5P; MICRORNA 542 5P; MICRORNA 572; MICRORNA 638; MICRORNA 93; MITOGEN ACTIVATED PROTEIN KINASE; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; MALE; MICROARRAY ANALYSIS; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCH BIOPSY; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; AGED, 80 AND OVER; CARCINOMA, BASAL CELL; CASE-CONTROL STUDIES; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICROARRAY ANALYSIS; MICRORNAS; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RNA, NEOPLASM; SKIN NEOPLASMS;

EID: 84867058340     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2012.11022.x     Document Type: Article

References (39)

1. Grimmer H,. Histological picture report no.20l. Basalioma of the vulva (basal cell carcinoma Krompecher 1900). Z Haut Geschlechtskr 1967; 43: 25-40.
2. Goppner D, Leverkus M,. Basal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease. J Skin Cancer 2011; 2011: 650258.
3. Sand M, Gambichler T, Sand D, et al. MicroRNAs and the skin: tiny players in the body's largest organ. J Dermatol Sci 2009; 53: 169-75.
4. Sand M, Gambichler T, Skrygan M, et al. Expression levels of the microRNA processing enzymes Drosha and Dicer in epithelial skin cancer. Cancer Invest 2010; 28: 649-53.
5. Sand M, Skrygan M, Georgas D, et al. Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components Argonaute-1, Argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer. Mol Carcinog 2011; Oct 24, doi:10.1002/mc.20861. [Epub ahead of print] in press.
6. Zhang JD, Biczok R, Ruschhaupt M,. The ddCt Algorithm for the Analysis of Quantitative Real-Time PCR (qRT-PCR). Bioconductor 2.10 software. Available at: http://www.bioconductor.org/packages/release/bioc/html/ddCt.html (last accessed 6 June 2012).
7. Edgar R, Domrachev M, Lash AE,. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002; 30: 207-10.
8. Sokal R, Michener C,. A statistical method for evaluating systematic relationships. Univ Kans Sci Bull 1958; 38: 1409-38.
9. Quackenbush J,. Computational analysis of microarray data. Nat Rev Genet 2001; 2: 418-27.
10. Benjamini Y, Drai D, Elmer G, et al. Controlling the false discovery rate in behavior genetics research. Behav Brain Res 2001; 125: 279-84.
11. Jiang Q, Wang Y, Hao Y, et al. miR2Disease: a manually curated database for microRNA deregulation in human disease. Nucleic Acids Res 2009; 37: D98-104.
12. Epstein EH,. Basal cell carcinomas: attack of the hedgehog. Nat Rev Cancer 2008; 8: 743-54.
13. Johnson GL, Lapadat R,. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002; 298: 1911-12.
14. Paroo Z, Ye X, Chen S, et al. Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell 2009; 139: 112-22.
15. Hutchin ME, Kariapper MS, Grachtchouk M, et al. Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev 2005; 19: 214-23.
16. Katoh Y, Katoh M,. Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review). Int J Mol Med 2008; 22: 271-5.
17. Reifenberger J, Wolter M, Knobbe CB, et al. Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas. Br J Dermatol 2005; 152: 43-51.
18. Raffel C, Jenkins RB, Frederick L, et al. Sporadic medulloblastomas contain PTCH mutations. Cancer Res 1997; 57: 842-5.
19. Zurawel RH, Allen C, Chiappa S, et al. Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma. Genes Chromosom Cancer 2000; 27: 44-51.
20. He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005; 435: 828-33.
21. Al-Nakhle H, Burns PA, Cummings M, et al. Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer. Cancer Res 2010; 70: 4778-84.
22. Uziel T, Karginov FV, Xie S, et al. The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma. Proc Natl Acad Sci U S A 2009; 106: 2812-17.
23. Hashimoto Y, Akiyama Y, Otsubo T, et al. Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. Carcinogenesis 2010; 31: 777-84.
24. Proweller A, Tu L, Lepore JJ, et al. Impaired notch signaling promotes de novo squamous cell carcinoma formation. Cancer Res 2006; 66: 7438-44.
25. van der Schroeff JG, Evers LM, Boot AJ, et al. Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin. J Invest Dermatol 1990; 94: 423-5.
26. Guttilla IK, White BA,. Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells. J Biol Chem 2009; 284: 23204-16.
27. Katoh M,. Human FOX gene family (review). Int J Oncol 2004; 25: 1495-500.
28. Teh MT, Wong ST, Neill GW, et al. FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res 2002; 62: 4773-80.
29. Regl G, Kasper M, Schnidar H, et al. Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2. Cancer Res 2004; 64: 7724-31.
30. Li Y, Tan W, Neo TW, et al. Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma. Cancer Sci 2009; 100: 1234-42.
31. Regl G, Kasper M, Schnidar H, et al. The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells. Oncogene 2004; 23: 1263-74.
32. Pierce AM, Gimenez-Conti IB, Schneider-Broussard R, et al. Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53. Proc Natl Acad Sci U S A 1998; 95: 8858-63.
33. Berton TR, Mitchell DL, Guo R, et al. Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation. Oncogene 2005; 24: 2449-60.
34. Nandakumar V, Vaid M, Tollefsbol TO, et al. Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice. Carcinogenesis 2011; 32: 597-604.
35. Nguyen T, Kuo C, Nicholl MB, et al. Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Epigenetics 2011; 6: 388-94.
36. DiGiovanni J, Bol DK, Wilker E, et al. Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion. Cancer Res 2000; 60: 1561-70.
37. Fernandez C, Tatard VM, Bertrand N, et al. Differential modulation of sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network. Dev Neurosci 2010; 32: 59-70.
38. Parathath SR, Mainwaring LA, Fernandez LA, et al. Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors. Development 2008; 135: 3291-300.
39. Shi B, Sepp-Lorenzino L, Prisco M, et al. Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem 2007; 282: 32582-90.