FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling

PLoS Genetics

Volumn 11, Issue 6, 2015, Pages

  Zhou, Siru ^a   Xie, Yangli ^a   Tang, Junzhou ^a   Huang, Junlan ^a   Huang, Qizhao ^a   Xu, Wei ^a   Wang, Zuqiang ^a   Luo, Fengtao ^a   Wang, Quan ^a   Chen, Hangang ^a   Du, Xiaolan ^a   Shen, Yue ^a   Chen, Di ^b   Chen, Lin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; MITOGEN ACTIVATED PROTEIN KINASE; SONIC HEDGEHOG PROTEIN; FGFR3 PROTEIN, MOUSE; IHH PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CARTILAGE CELL; CHONDROMA; DISEASE SEVERITY; DOWN REGULATION; ENCHONDROMA; FEMUR; HISTOLOGY; MOUSE; NONHUMAN; OSTEOCHONDROMA; PERINATAL PERIOD; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TIBIA; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CHONDROCYTE; DEFICIENCY; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

ERINACEIDAE; MUS;

ANIMALS; CELL LINE; CELLS, CULTURED; CHONDROCYTES; CHONDROMA; HEDGEHOG PROTEINS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; UP-REGULATION;

EID: 84937788577     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005214     Document Type: Article

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