Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones

Bone

Volumn 48, Issue 5, 2011, Pages 979-987

  Zak, Beverly M ^a   Schuksz, Manuela ^a   Koyama, Eiki ^b   Mundy, Christina ^b   Wells, Dan E ^c   Yamaguchi, Yu ^d   Pacifici, Maurizio ^b   Esko, Jeffrey D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c University of Houston   (United States)

^d BURNHAM INSTITUTE   (United States)

Author keywords

Chondrocytes; Exostosins; Heparan sulfate; Mouse mutants; Multiple hereditary exostoses

Indexed keywords

EXT1 PROTEIN; EXT2 PROTEIN; FIBROBLAST GROWTH FACTOR 18; HEPARAN SULFATE; N ACETYLGLUCOSAMINYLTRANSFERASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE TISSUE; CARTILAGE CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; EXOSTOSIS; FIBROBLAST; GROWTH PLATE; HEREDITARY MULTIPLE EXOSTOSIS; HETEROZYGOSITY LOSS; IN VITRO STUDY; LONG BONE; MOUSE; NONHUMAN; PATHOGENESIS; PERICHONDRIUM; PHENOTYPE; PROTEIN EXPRESSION; RIB;

ANIMALS; CELLS, CULTURED; EXOSTOSES; FIBROBLAST GROWTH FACTORS; GROWTH PLATE; HEPARITIN SULFATE; HETEROZYGOTE; MICE; MICE, MUTANT STRAINS; N-ACETYLGLUCOSAMINYLTRANSFERASES; RIBS;

EID: 79954574438     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.02.001     Document Type: Article

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