Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia

Journal of Biological Chemistry

Volumn 273, Issue 21, 1998, Pages 13007-13014

  Legeai Mallet, Laurence ^a   Benoist Lasselin, Catherine ^a   Delezoide, Anne Lise ^a   Munnich, Arnold ^a   Bonaventure, Jacky ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX;

APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; FETUS; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THANATOPHORIC DWARFISM;

APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELLS, CULTURED; DNA-BINDING PROTEINS; ENZYME ACTIVATION; FETAL DISEASES; GENOTYPE; GROWTH PLATE; HUMANS; IMMUNOHISTOCHEMISTRY; MUTATION; PHENOTYPE; PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; RECEPTORS, FIBROBLAST GROWTH FACTOR; STAT1 TRANSCRIPTION FACTOR; THANATOPHORIC DYSPLASIA; TRANS-ACTIVATORS;

EID: 0032557555     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.21.13007     Document Type: Article

References (41)

1. Johnson, D. E., and Williams, L. T. (1993) Adv. Cancer Res. 60, 1-41
2. Spivak-Kroizman, T., Lemmon, M. A., Dikic, I., Ladbury, J. E., Pinchasi, D., Huang, J., Jaye, M., Crumley, G., Schlessinger, J., and Lax, I. (1994) Cell 79, 1015-1024
3. Huang, J., Mohammadi, M., Rodrigues, G. A., and Schlessinger J. (1995) J. Biol. Chem. 270, 5065-5072
4. Kanai, M., Göke, M., Tsunekawa, S., and Podolsky, D. K. (1997) J. Biol. Chem. 272, 6621-6628
5. Rousseau, F., Bonaventure, J., Legeai-Mallet, L., Pelet, A., Rozet, J-M., Maroteaux, P., Le Merrer, M., and Munnich, A. (1994) Nature 371, 252-254
6. Shiang, R., Thompson, L. M., Zhu, Y-Z, Church, D. M., Fielder, T. J., Bocian, M., Winokur, S. T., and Wasmuth, J. J. (1994) Cell 78, 336-342
7. Bellus, G. A., McIntosh, I., Smith, A. E., Aylsworth, A. S., Kaitila, I., Horton, W., Greenhaw, G. A., Hecht, J. T., and Francomano, C. (1995) Nat. Genet. 10, 357-359
8. Rousseau, F., Saugier, P., Le Merrer, M., Munnich, A., Delezoide, A-L., Maroteaux, P., and Bonaventure, J. (1995) Nat. Genet. 10, 11-12
9. Tavormina, P. L., Shiang, R., Thompson, L, Zhu, Y-Z., Wilkin, D. J., Lachman, R., Wilcox, W. R., Rimoin, D., Cohn, D., and Wasmuth, J. J. (1995) Nat. Genet. 9, 321-328
10. Deng, C., Wynshaw-Boris, A., Zhou, F., Kuo, A., and Leder, P, (1996) Cell 84, 911-921
11. Colvin, J. S., Bohne, B. A., Harding, G. W., McEwen, D. G., and Ornitz, D. M. (1996) Nat. Genet. 12, 390-397
12. Webster, M., and Donoghue, D. J. (1996) EMBO J. 15, 520-527
13. Naski, M. C., Wang, Q., Xu, J., and Ornitz, D. (1996) Nat. Genet. 13, 233-237
14. Webster, M. K., d'Avis, P. Y., Robertson, S. C., and Donoghue, D. J. (1996) Mol. Cell. Biol. 16, 4081-4087
15. Su, W-C. S., Kitagawa, M., Xue, N., Xie, B., Garofalo, S., Cho, J., Deng, C., Horton, W., and Fu, X-Y. (1997) Nature 386, 288-292
16. Rousseau, F., El Ghouzzi, V., Delezoide, A. L., Legeai-Mallet, L., Le Merrer, M., Munnich, A., and Bonaventure, J. (1996) Hum. Mol. Genet. 5, 509-512
17. Bonaventure, J., Kadhom, N., Cohen-Solal, L., Ng, K. H., Bourguignon, J., Lasselin, C., and Freisinger, P. (1994) Exp. Cell Res. 212, 97-104
18. Seger, R., Seger, D., Reszka, A. A., Munar, E. S., Eldar-Fmkelman H., Dobrowolska, G., Jensen, A. M., Campbell, J. S., Fischer, E. H., and Krebs, E. G. (1994) J. Biol. Chem. 269, 25699-25709
19. Posada, J., and Cooper, J. A. (1992) Science 255, 182-184
20. Chellaiah, A., McEwen, D. G., Werner, S., Xu, J., and Ornitz, D. (1994) J. Biol. Chem. 269, 11620-11627
21. Hecht, D., Zimmerman, R, Bedford, M., Avivi, A., and Yayon, A. (1995) Growth Factors 12, 223-233
22. Santos-Ocampo, S., Colvin, J. S., Chellaiah, A., and Ornitz, D. M. (1996) J. Biol. Chem. 271, 1726-1731
23. Delezoide, A. L., Lasselin-Benoist, C., Legeai-Mallet, L., Brice, P, Senée, V., Yayon, A., Munnich, A., Vekemans, M., and Bonaventure, J. (1997) Hum. Mol. Genet. 11, 1899-1906
24. Peters, K., Ornitz, D., Werner, S., and Williams, L. (1993) Dev. Biol. 156, 423-430
25. Peters, K. G., Werner, S., Chen, G., and Williams, L. T. (1992) Development 114, 233-243
26. Orr-Urtreger, A., Givol, D., Yayon, A., Yarden, Y., and Lonai, P. (1991) Development 113, 1419-1434
27. Marshall, C. J. (1995) Cell 80, 179-185
28. Thompson, L. M., Raffioni, S., Wasmuth, J. J., and Bradshaw, R. (1997) Mol. Cell. Biol. 17, 4169-4177
29. Chin, Y. E., Kitagawa, M., Kuida, K., Flavell, R. A., and Fu, X-Y. (1997) Mol. Cell. Biol. 17, 5328-5337
30. Johnston, C. L., Cox, H. C., Gomm, J. J., and Coombes, R. C. (1995) J. Biol. Chem. 270, 30643-30650
31. Kilkenny, D. M., and Hill, D. (1996) Endocrinology 137, 5078-5089
32. Prudovsky, I., Savion, N., Zhan, X., Friesel, R., Xu, J., Hou, J., McKeehan, W. L., and Maciag, T. (1994) J. Biol. Chem. 269, 31720-31724
33. Maher, P. A. (1996) J. Cell. Biol. 134, 529-536
34. Mason, I. J. (1994) Cell 78, 547-552
35. Roach, H. I., Erenpreisa, J., and Aigner, T. (1995) J. Cell Biol. 131, 483-494
36. Gibson, G., Lin, D-L., and Roque, M. (1997) Exp. Cell Res. 233, 372-382
37. Amling, M., Neff, L., Tanaka, S., Inoue, D., Kuida, K., Weir, E., Philbrick, W. M., Broadus, A. E., and Baron, R. (1997) J. Cell Biol. 136, 205-213
38. Zha, H., Fisk, H. A., Yaffe, M. P., Mahajan, N., Herman, B., and Reed, J. C. (1996) Mol. Cell. Biol. 16, 6494-6508
39. Salvesen, G. S., and Dixit, V. M. (1997) Cell 91, 443-446
40. Kumar, A., Commane, M., Flickinger, T. W., Horvath, C. M., and Stark, G. R. (1997) Science 278, 1630-1632
41. Chow, R. L., Roux, G. D., Roghani, M., Palmer M. A., Rifkin D. B., Moscatelli D. A., and Lang R. A. (1995) Development 121, 4383-4393