Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 11, 2015, Pages 2261-2268

  Richardson, B G ^a   Jain, A D ^a   Speltz, T E ^a   Moore, T W ^a,b  

^a Chicago College of Pharmacy   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Adaptive stress response; Cul3; Keap1; Nrf2; Nrf2 activator; Nrf2 repressor; Nrf2 Keap1 interaction; Protein protein interaction

Indexed keywords

KEAP1 PROTEIN, HUMAN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PROTEIN BINDING; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NRF2;

AGONISTS; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; MODELS, MOLECULAR; NF-E2-RELATED FACTOR 2; PROTEIN BINDING; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

EID: 84937762296     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.04.019     Document Type: Review

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