Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction

Free Radical Biology and Medicine

Volumn 52, Issue 2, 2012, Pages 444-451

  Hancock, Rowena ^a   Bertrand, Hélène C ^a   Tsujita, Tadayuki ^b   Naz, Shama ^a   El Bakry, Ayman ^a   Laoruchupong, Jitnueng ^a   Hayes, John D ^b   Wells, Geoff ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cancer chemoprevention; Compound screening; Fluorescence polarization; Free radicals; Keap1; Nrf2

Indexed keywords

HYBRID PROTEIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PROTEIN INHIBITOR; PROTEIN P62; PROTHYMOSIN ALPHA; SYNTHETIC PEPTIDE; TRANSCRIPTION FACTOR NRF2;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FLUORESCENCE POLARIZATION; HIGH THROUGHPUT SCREENING; HUMAN; METHODOLOGY; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; DRUG SCREENING ASSAYS, ANTITUMOR; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NF-E2-RELATED FACTOR 2; OLIGOPEPTIDES; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; THYMOSIN;

EID: 84855443480     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.10.486     Document Type: Article

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