Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2

Science Signaling

Volumn 8, Issue 386, 2015, Pages

  Vila Bedmar, Rocio ^a,b   Cruces Sande, Marta ^a,b   Lucas, Elisa ^a,b   Willemen, Hanneke L D M ^c   Heijnen, Cobi J ^c,d   Kavelaars, Annemieke ^c,d   Mayor, Federico ^a,b   Murga, Cristina ^a,b  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^b Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas   (Spain)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CARNITINE PALMITOYLTRANSFERASE I; G PROTEIN COUPLED RECEPTOR KINASE 2; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INSULIN; PROTEIN KINASE B; TAMOXIFEN; UNCOUPLING PROTEIN 1; ADRBK1 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DIET INDUCED OBESITY; ENZYME PHOSPHORYLATION; EPIDIDYMIS FAT; FAT MASS; FATTY ACID OXIDATION; FATTY LIVER; GENE DELETION; GENETIC PROCEDURES; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; METABOLIC REGULATION; METABOLIC SYNDROME X; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; OBESITY; PATHOLOGY;

ANIMALIA; MURINAE;

ADIPOSITY; ANIMALS; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GLUCOSE; HUMANS; INSULIN RESISTANCE; MICE; MICE, KNOCKOUT; OBESITY;

EID: 84937704367     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaa4374     Document Type: Article

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