Ferret models of viral pathogenesis

Virology

Volumn 479-480, Issue , 2015, Pages 259-270

  Enkirch, T ^a   von Messling, V ^a  

^a PAUL EHRLICH INSTITUT   (Germany)

Author keywords

Animal model; Ferret; Immune response evaluation; Influenza viruses; Paramyxoviruses; Pathogenesis studies; Vaccine and drug safety and efficacy assessment

Indexed keywords

ANIMAL; DISEASE MODEL; DISEASE PREDISPOSITION; FERRET; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; INFECTION CONTROL; ORTHOMYXOVIRIDAE; PARAMYXOVIRINAE; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT INFECTIONS; VIRUS DISEASES;

ANIMALS; COMMUNICABLE DISEASE CONTROL; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; FERRETS; HOST-PATHOGEN INTERACTIONS; HUMANS; ORTHOMYXOVIRIDAE; PARAMYXOVIRINAE; RESPIRATORY TRACT INFECTIONS; VIRUS DISEASES;

EID: 84937511489     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.03.017     Document Type: Review

References (216)

1. Ann J., Samant M., Rheaume C., Dumas C., Beaulieu E., Morasse A., Mallett C., Hamelin M.E., Papadopoulou B., Boivin G. Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines. Vaccine 2014, 32(43):5730-5739.
2. Ball R.S. Husbandry and management of the domestic ferret. Lab Anim (NY) 2002, 31(5):37-42.
3. Belser J.A., Gustin K.M., Katz J.M., Maines T.R., Tumpey T.M. Influenza virus infectivity and virulence following ocular-only aerosol inoculation of ferrets. J. Virol. 2014, 88(17):9647-9654.
4. Belser J.A., Gustin K.M., Maines T.R., Blau D.M., Zaki S.R., Katz J.M., Tumpey T.M. Pathogenesis and transmission of triple-reassortant swine H1N1 influenza viruses isolated before the 2009 H1N1 pandemic. J. Virol. 2011, 85(4):1563-1572.
5. Belser J.A., Gustin K.M., Maines T.R., Pantin-Jackwood M.J., Katz J.M., Tumpey T.M. Influenza virus respiratory infection and transmission following ocular inoculation in ferrets. PLoS Pathog. 2012, 8(3):e1002569.
6. Belser J.A., Gustin K.M., Pearce M.B., Maines T.R., Zeng H., Pappas C., Sun X., Carney P.J., Villanueva J.M., Stevens J., Katz J.M., Tumpey T.M. Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice. Nature 2013, 501(7468):556-559.
7. Belser J.A., Szretter K.J., Katz J.M., Tumpey T.M. Use of animal models to understand the pandemic potential of highly pathogenic avian influenza viruses. Adv. Virus Res. 2009, 73:55-97.
8. Bertram S., Glowacka I., Steffen I., Kuhl A., Pohlmann S. Novel insights into proteolytic cleavage of influenza virus hemagglutinin. Rev. Med. Virol. 2010, 20(5):298-310.
9. Bixler H., Ellis C. Ferret care and husbandry. Veterinary clinics of North America. Exotic Anim. Pract. 2004, 7:227-255.
10. Bodewes R., de Mutsert G., van der Klis F.R., Ventresca M., Wilks S., Smith D.J., Koopmans M., Fouchier R.A., Osterhaus A.D., Rimmelzwaan G.F. Prevalence of antibodies against seasonal influenza A and B viruses in children in Netherlands. Clin. Vaccine Immunol. 2011, 18(3):469-476.
11. Bodewes R., Kreijtz J.H., van Amerongen G., Hillaire M.L., Vogelzang-van Trierum S.E., Nieuwkoop N.J., van Run P., Kuiken T., Fouchier R.A., Osterhaus A.D., Rimmelzwaan G.F. Infection of the upper respiratory tract with seasonal influenza A(H3N2) virus induces protective immunity in ferrets against infection with A(H1N1)pdm09 virus after intranasal, but not intratracheal, inoculation. J. Virol. 2013, 87(8):4293-4301.
12. Boltz D.A., Ilyushina N.A., Arnold C.S., Babu Y.S., Webster R.G., Govorkova E.A. Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice. Antiviral Res. 2008, 80(2):150-157.
13. Boltz D.A., Rehg J.E., McClaren J., Webster R.G., Govorkova E.A. Oseltamivir prophylactic regimens prevent H5N1 influenza morbidity and mortality in a ferret model. J. Infect. Dis. 2008, 197(9):1315-1323.
14. Bonami F., Rudd P.A., von Messling V. Disease duration determines canine distemper virus neurovirulence. J. Virol. 2007, 81(21):12066-12070.
15. Bonaparte M.I., Dimitrov A.S., Bossart K.N., Crameri G., Mungall B.A., Bishop K.A., Choudhry V., Dimitrov D.S., Wang L.F., Eaton B.T., Broder C.C. Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus. Proc. Natl. Acad. Sci. USA 2005, 102(30):10652-10657.
16. Bossart K.N., Crameri G., Dimitrov A.S., Mungall B.A., Feng Y.R., Patch J.R., Choudhary A., Wang L.F., Eaton B.T., Broder C.C. Receptor binding, fusion inhibition, and induction of cross-reactive neutralizing antibodies by a soluble G glycoprotein of Hendra virus. J. Virol. 2005, 79(11):6690-6702.
17. Bossart K.N., Zhu Z., Middleton D., Klippel J., Crameri G., Bingham J., McEachern J.A., Green D., Hancock T.J., Chan Y.P., Hickey A.C., Dimitrov D.S., Wang L.F., Broder C.C. A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection. PLoS Pathog. 2009, 5(10):e1000642.
18. Bouvier N.M., Lowen A.C. Animal models for influenza virus pathogenesis and transmission. Viruses 2010, 2(8):1530-1563.
19. Bragstad K., Martel C.J., Thomsen J.S., Jensen K.L., Nielsen L.P., Aasted B., Fomsgaard A. Pandemic influenza 1918 H1N1 and 1968 H3N2 DNA vaccines induce cross-reactive immunity in ferrets against infection with viruses drifted for decades. Influenza Other Respir. Viruses 2011, 5(1):13-23.
20. Brankston G., Gitterman L., Hirji Z., Lemieux C., Gardam M. Transmission of influenza A in human beings. Lancet Infect. Dis. 2007, 7(4):257-265.
21. Bresson J.L., Perronne C., Launay O., Gerdil C., Saville M., Wood J., Hoschler K., Zambon M.C. Safety and immunogenicity of an inactivated split-virion influenza A/Vietnam/1194/2004 (H5N1) vaccine: phase I randomised trial. Lancet 2006, 367(9523):1657-1664.
22. Bright R.A., Medina M.J., Xu X., Perez-Oronoz G., Wallis T.R., Davis X.M., Povinelli L., Cox N.J., Klimov A.I. Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 2005, 366(9492):1175-1181.
23. Bright R.A., Shay D.K., Shu B., Cox N.J., Klimov A.I. Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. JAMA 2006, 295(8):891-894.
24. Broder C.C., Xu K., Nikolov D.B., Zhu Z., Dimitrov D.S., Middleton D., Pallister J., Geisbert T.W., Bossart K.N., Wang L.F. A treatment for and vaccine against the deadly Hendra and Nipah viruses. Antiviral Res. 2013, 100(1):8-13.
25. Bruder C.E., Yao S., Larson F., Camp J.V., Tapp R., McBrayer A., Powers N., Granda W.V., Jonsson C.B. Transcriptome sequencing and development of an expression microarray platform for the domestic ferret. BMC Genomics 2010, 11:251.
26. Butler D. Clusters of coronavirus cases put scientists on alert. Nature 2012, 492(7428):166-167.
27. Cameron C.M., Cameron M.J., Bermejo-Martin J.F., Ran L., Xu L., Turner P.V., Ran R., Danesh A., Fang Y., Chan P.K., Mytle N., Sullivan T.J., Collins T.L., Johnson M.G., Medina J.C., Rowe T., Kelvin D.J. Gene expression analysis of host innate immune responses during Lethal H5N1 infection in ferrets. J. Virol. 2008, 82(22):11308-11317.
28. Capraro G.A., Johnson J.B., Kock N.D., Parks G.D. Virus growth and antibody responses following respiratory tract infection of ferrets and mice with WT and P/V mutants of the paramyxovirus Simian Virus 5. Virology 2008, 376(2):416-428.
29. Chen H., Bright R.A., Subbarao K., Smith C., Cox N.J., Katz J.M., Matsuoka Y. Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice. Virus Res. 2007, 128(1-2):159-163.
30. Chu Y.K., Ali G.D., Jia F., Li Q., Kelvin D., Couch R.C., Harrod K.S., Hutt J.A., Cameron C., Weiss S.R., Jonsson C.B. The SARS-CoV ferret model in an infection-challenge study. Virology 2008, 374(1):151-163.
31. Clayton B.A., Middleton D., Bergfeld J., Haining J., Arkinstall R., Wang L., Marsh G.A. Transmission routes for nipah virus from Malaysia and Bangladesh. Emerg. Infect. Dis. 2012, 18(12):1983-1993.
32. Clegg C.H., Roque R., Perrone L.A., Rininger J.A., Bowen R., Reed S.G. GLA-AF, an emulsion-free vaccine adjuvant for pandemic influenza. PLoS One 2014, 9(2):e88979.
33. Clingerman K.J., Fox J.G., Walke M., National Agricultural Library (U.S.), and Massachusetts Institute of Technology Ferrets as Laboratory Animals: a Bibliography 1991, Bibliographies and Literature of Agriculture U.S. Department of Agriculture Massachusetts Institute of Technology, Beltsville, MD, Cambridge, MA.
34. Coates H.V., Chanock R.M. Experimental infection with respiratory syncytial virus in several species of animals. Amin. J. Hyg. 1962, 76:302-312.
35. Colasurdo G.N., Hemming V.G., Prince G.A., Gelfand A.S., Loader J.E., Larsen G.L. Human respiratory syncytial virus produces prolonged alterations of neural control in airways of developing ferrets. Am. J. Respir. Crit. Care Med. 1998, 157(5, Part 1):1506-1511.
36. Collins P.L., Graham B.S. Viral and host factors in human respiratory syncytial virus pathogenesis. J. Virol. 2008, 82(5):2040-2055.
37. Dahlem P., van Aalderen W.M., Hamaker M.E., Dijkgraaf M.G., Bos A.P. Incidence and short-term outcome of acute lung injury in mechanically ventilated children. Eur. Respir. J. 2003, 22(6):980-985.
38. Darnell M.E., Plant E.P., Watanabe H., Byrum R., St.Claire M., Ward J.M., Taylor D.R. Severe acute respiratory syndrome coronavirus infection in vaccinated ferrets. J. Infect. Dis. 2007, 196(9):1329-1338.
39. De Groot A.S., Ardito M., Terry F., Levitz L., Ross T., Moise L., Martin W. Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design. Hum. Vaccin. Immunother. 2013, 9(5):950-956.
40. de Jong M.D., Simmons C.P., Thanh T.T., Hien V.M., Smith G.J., Chau T.N., Hoang D.M., Chau N.V., Khanh T.H., Dong V.C., Qui P.T., Cam B.V., Ha do Q., Guan Y., Peiris J.S., Chinh N.T., Hien T.T., Farrar J. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat. Med. 2006, 12(10):1203-1207.
41. Ding Y., He L., Zhang Q., Huang Z., Che X., Hou J., Wang H., Shen H., Qiu L., Li Z., Geng J., Cai J., Han H., Li X., Kang W., Weng D., Liang P., Jiang S. Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J. Pathol. 2004, 203(2):622-630.
42. Drosten C., Gunther S., Preiser W., van der Werf S., Brodt H.R., Becker S., Rabenau H., Panning M., Kolesnikova L., Fouchier R.A., Berger A., Burguiere A.M., Cinatl J., Eickmann M., Escriou N., Grywna K., Kramme S., Manuguerra J.C., Muller S., Rickerts V., Sturmer M., Vieth S., Klenk H.D., Osterhaus A.D., Schmitz H., Doerr H.W. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N. Engl. J. Med. 2003, 348(20):1967-1976.
43. Duan Y., Gu H., Chen R., Zhao Z., Zhang L., Xing L., Lai C., Zhang P., Li Z., Zhang K., Wang Z., Zhang S., Wang X., Yang P. Response of mice and ferrets to a monovalent influenza A (H7N9) split vaccine. PLoS One 2014, 9(6):e99322.
44. Durchfeld B., Baumgartner W., Krakowka S. Intranasal infection of ferrets (Mustela putorius furo) with canine parainfluenza virus. Zentralbl. Veterinarmed. B 1991, 38(7):505-512.
45. Elizan T.S., Fabiyi A., Sever J.L. Experimental teratogenesis in ferrets using Rubella virus. J. Mt. Sinai Hosp. N. Y. 1969, 36(2):103-107.
46. Fabiyi A., Gitnick G.L., Sever J.L. Chronic rubella virus infection in the ferret (Mustela putorius fero) puppy. Proc. Soc. Exp. Biol. Med. 1967, 125(3):766-771.
47. Falsey A.R., Erdman D., Anderson L.J., Walsh E.E. Human metapneumovirus infections in young and elderly adults. J. Infect. Dis. 2003, 187(5):785-790.
48. Falsey A.R., Hennessey P.A., Formica M.A., Cox C., Walsh E.E. Respiratory syncytial virus infection in elderly and high-risk adults. N. Engl. J. Med. 2005, 352(17):1749-1759.
49. Fan S., Zhou L., Wu D., Gao X., Pei E., Wang T., Gao Y., Xia X. A novel highly pathogenic H5N8 avian influenza virus isolated from a wild duck in China. Influenza Other Respir. Viruses 2014, 8(6):646-653.
50. Fang Y., Rowe T., Leon A.J., Banner D., Danesh A., Xu L., Ran L., Bosinger S.E., Guan Y., Chen H., Cameron C.C., Cameron M.J., Kelvin D.J. Molecular characterization of in vivo adjuvant activity in ferrets vaccinated against influenza virus. J. Virol. 2010, 84(17):8369-8388.
51. Fonville J.M., Wilks S.H., James S.L., Fox A., Ventresca M., Aban M., Xue L., Jones T.C., Le N.M., Pham Q.T., Tran N.D., Wong Y., Mosterin A., Katzelnick L.C., Labonte D., Le T.T., van der Net G., Skepner E., Russell C.A., Kaplan T.D., Rimmelzwaan G.F., Masurel N., de Jong J.C., Palache A., Beyer W.E., Le Q.M., Nguyen T.H., Wertheim H.F., Hurt A.C., Osterhaus A.D., Barr I.G., Fouchier R.A., Horby P.W., Smith D.J. Antibody landscapes after influenza virus infection or vaccination. Science 2014, 346(6212):996-1000.
52. Fox J.G. Biology and Diseases of the Ferret 1998, Williams & Wilkins, Baltimore. 2nd ed.
53. Frenzke M., Sawatsky B., Wong X.X., Delpeut S., Mateo M., Cattaneo R., von Messling V. Nectin-4-dependent measles virus spread to the cynomolgus monkey tracheal epithelium: role of infected immune cells infiltrating the lamina propria. J. Virol. 2013, 87(5):2526-2534.
54. Furuta Y., Gowen B.B., Takahashi K., Shiraki K., Smee D.F., Barnard D.L. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013, 100(2):446-454.
55. Gale N.W., Baluk P., Pan L., Kwan M., Holash J., DeChiara T.M., McDonald D.M., Yancopoulos G.D. Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev. Biol. 2001, 230(2):151-160.
56. Gambotto A., Barratt-Boyes S.M., de Jong M.D., Neumann G., Kawaoka Y. Human infection with highly pathogenic H5N1 influenza virus. Lancet 2008, 371(9622):1464-1475.
57. Gerhard W. The role of the antibody response in influenza virus infection. Curr. Top. Microbiol. Immunol. 2001, 260:171-190.
58. Govorkova E.A., Ilyushina N.A., Boltz D.A., Douglas A., Yilmaz N., Webster R.G. Efficacy of oseltamivir therapy in ferrets inoculated with different clades of H5N1 influenza virus. Antimicrob. Agents Chemother. 2007, 51(4):1414-1424.
59. Govorkova E.A., Webby R.J., Humberd J., Seiler J.P., Webster R.G. Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferrets against homologous and heterologous challenge. J. Infect. Dis. 2006, 194(2):159-167.
60. Gramberg T., Hofmann H., Moller P., Lalor P.F., Marzi A., Geier M., Krumbiegel M., Winkler T., Kirchhoff F., Adams D.H., Becker S., Munch J., Pohlmann S. LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus. Virology 2005, 340(2):224-236.
61. Gu J., Gong E., Zhang B., Zheng J., Gao Z., Zhong Y., Zou W., Zhan J., Wang S., Xie Z., Zhuang H., Wu B., Zhong H., Shao H., Fang W., Gao D., Pei F., Li X., He Z., Xu D., Shi X., Anderson V.M., Leong A.S. Multiple organ infection and the pathogenesis of SARS. J. Exp. Med. 2005, 202(3):415-424.
62. Gustin K.M., Katz J.M., Tumpey T.M., Maines T.R. Comparison of the levels of infectious virus in respirable aerosols exhaled by ferrets infected with influenza viruses exhibiting diverse transmissibility phenotypes. J. Virol. 2013, 87(14):7864-7873.
63. Hai T., Teng F., Guo R., Li W., Zhou Q. One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Res. 2014, 24(3):372-375.
64. Hall C.B., Douglas R.G., Schnabel K.C., Geiman J.M. Infectivity of respiratory syncytial virus by various routes of inoculation. Infect. Immun. 1981, 33(3):779-783.
65. Hamir A.N., Niezgoda M., Rupprecht C.E. Recovery from and clearance of rabies virus in a domestic ferret. J. Am. Assoc. Lab. Anim. Sci. 2011, 50(2):248-251.
66. Hamming I., Timens W., Bulthuis M.L., Lely A.T., Navis G., van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J. Pathol. 2004, 203(2):631-637.
67. Hanlon C.A., Kuzmin I.V., Blanton J.D., Weldon W.C., Manangan J.S., Rupprecht C.E. Efficacy of rabies biologics against new lyssaviruses from Eurasia. Virus Res. 2005, 111(1):44-54.
68. Hatta M., Gao P., Halfmann P., Kawaoka Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 2001, 293(5536):1840-1842.
69. Hayman D.T., Suu-Ire R., Breed A.C., McEachern J.A., Wang L., Wood J.L., Cunningham A.A. Evidence of henipavirus infection in West African fruit bats. PLoS One 2008, 3(7):e2739.
70. Herfst S., Schrauwen E.J., Linster M., Chutinimitkul S., de Wit E., Munster V.J., Sorrell E.M., Bestebroer T.M., Burke D.F., Smith D.J., Rimmelzwaan G.F., Osterhaus A.D., Fouchier R.A. Airborne transmission of influenza A/H5N1 virus between ferrets. Science 2012, 336(6088):1534-1541.
71. Herlocher M.L., Truscon R., Fenton R., Klimov A., Elias S., Ohmit S.E., Monto A.S. Assessment of development of resistance to antivirals in the ferret model of influenza virus infection. J. Infect. Dis. 2003, 188(9):1355-1361.
72. Hoschler K., Thompson C., Casas I., Ellis J., Galiano M., Andrews N., Zambon M. Population susceptibility to North American and Eurasian swine influenza viruses in England, at three time points between 2004 and 2011. Euro Surveill. 2013, 18(36):pii=20578.
73. Hossain M.J., Gurley E.S., Montgomery J.M., Bell M., Carroll D.S., Hsu V.P., Formenty P., Croisier A., Bertherat E., Faiz M.A., Azad A.K., Islam R., Molla M.A., Ksiazek T.G., Rota P.A., Comer J.A., Rollin P.E., Luby S.P., Breiman R.F. Clinical presentation of nipah virus infection in Bangladesh. Clin. Infect. Dis. 2008, 46(7):977-984.
74. Hsu K.H., Lubeck M.D., Bhat B.M., Bhat R.A., Kostek B., Selling B.H., Mizutani S., Davis A.R., Hung P.P. Efficacy of adenovirus-vectored respiratory syncytial virus vaccines in a new ferret model. Vaccine 1994, 12(7):607-612.
75. Huang S.S., Banner D., Fang Y., Ng D.C., Kanagasabai T., Kelvin D.J., Kelvin A.A. Comparative analyses of pandemic H1N1 and seasonal H1N1, H3N2, and influenza B infections depict distinct clinical pictures in ferrets. PLoS One 2011, 6(11):e27512.
76. Huber V.C., McCullers J.A. Live attenuated influenza vaccine is safe and immunogenic in immunocompromised ferrets. J. Infect. Dis. 2006, 193(5):677-684.
77. Hui D.S., Memish Z.A., Zumla A. Severe acute respiratory syndrome vs. the Middle East respiratory syndrome. Curr. Opin. Pulm. Med. 2014, 20(3):233-241.
78. Imai M., Watanabe T., Hatta M., Das S.C., Ozawa M., Shinya K., Zhong G., Hanson A., Katsura H., Watanabe S., Li C., Kawakami E., Yamada S., Kiso M., Suzuki Y., Maher E.A., Neumann G., Kawaoka Y. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 2012, 486(7403):420-428.
79. Ivics Z., Hiripi L., Hoffmann O.I., Mates L., Yau T.Y., Bashir S., Zidek V., Landa V., Geurts A., Pravenec M., Rulicke T., Bosze Z., Izsvak Z. Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons. Nat. Protoc. 2014, 9(4):794-809.
80. Johnson-Delaney C.A., Orosz S.E. Ferret respiratory system: clinical anatomy, physiology, and disease. Vet. Clin. N. Am. Exot. Anim. Pract. 2011, 14(2):357-367. vii.
81. Johnson N.P., Mueller J. Updating the accounts: global mortality of the 1918-1920 "Spanish" influenza pandemic. Bull. Hist. Med. 2002, 76(1):105-115.
82. Johnson S., Oliver C., Prince G.A., Hemming V.G., Pfarr D.S., Wang S.C., Dormitzer M., O[U+05F3]Grady J., Koenig S., Tamura J.K., Woods R., Bansal G., Couchenour D., Tsao E., Hall W.C., Young J.F. Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virus. J. Infect. Dis. 1997, 176(5):1215-1224.
83. Kang Y.M., Song B.M., Lee J.S., Kim H.S., Seo S.H. Pandemic H1N1 influenza virus causes a stronger inflammatory response than seasonal H1N1 influenza virus in ferrets. Arch. Virol. 2011, 156(5):759-767.
84. Karlsson E.A., Ip H.S., Hall J.S., Yoon S.W., Johnson J., Beck M.A., Webby R.J., Schultz-Cherry S. Respiratory transmission of an avian H3N8 influenza virus isolated from a harbour seal. Nat. Commun. 2014, 5:4791.
85. Kim Y.-I., Pascua P.N.Q., Kwon H.-I., Lim G.-J., Kim E.-H., Yoon S.-W., Park S.-J., Kim S.M., Choi E.-J., Si Y.-J., Lee O.-J., Shim W.-S., Kim S.-W., Mo I.-P., Bae Y., Lim Y.T., Sung M.H., Kim C.-J., Webby R.J., Webster R.G., Choi Y.K. Pathobiological features of a novel, highly pathogenic avian influenza A(H5N8) virus. Emerg. Microbes Infect. 2014, 3:e75.
86. Kimble J.B., Angel M., Wan H., Sutton T.C., Finch C., Perez D.R. Alternative reassortment events leading to transmissible H9N1 influenza viruses in the ferret model. J. Virol. 2014, 88(1):66-71.
87. Koster F., Gouveia K., Zhou Y., Lowery K., Russell R., MacInnes H., Pollock Z., Layton R.C., Cromwell J., Toleno D., Pyle J., Zubelewicz M., Harrod K., Sampath R., Hofstadler S., Gao P., Liu Y., Cheng Y.S. Exhaled aerosol transmission of pandemic and seasonal H1N1 influenza viruses in the ferret. PLoS One 2012, 7(4):e33118.
88. Kreijtz J.H., Goeijenbier M., Moesker F.M., van den Dries L., Goeijenbier S., De Gruyter H.L., Lehmann M.H., Mutsert G., van de Vijver D.A., Volz A., Fouchier R.A., van Gorp E.C., Rimmelzwaan G.F., Sutter G., Osterhaus A.D. Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influenza A H5N1 vaccine: a randomised, double-blind phase 1/2a clinical trial. Lancet Infect. Dis. 2014, 14(12):1196-1207.
89. Kreijtz J.H., Kroeze E.J., Stittelaar K.J., de Waal L., van Amerongen G., van Trierum S., van Run P., Bestebroer T., Kuiken T., Fouchier R.A., Rimmelzwaan G.F., Osterhaus A.D. Low pathogenic avian influenza A(H7N9) virus causes high mortality in ferrets upon intratracheal challenge: a model to study intervention strategies. Vaccine 2013, 31(43):4995-4999.
90. Kreijtz J.H., Suzer Y., Bodewes R., Schwantes A., van Amerongen G., Verburgh R.J., de Mutsert G., van den Brand J., van Trierum S.E., Kuiken T., Fouchier R.A., Osterhaus A.D., Sutter G., Rimmelzwaan G.F. Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model. J. Gen. Virol. 2010, 91(Part 11):2745-2752.
91. Krumm S.A., Yan D., Hovingh E.S., Evers T.J., Enkirch T., Reddy G.P., Sun A., Saindane M.T., Arrendale R.F., Painter G., Liotta D.C., Natchus M.G., von Messling V., Plemper R.K. An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model. Sci. Transl. Med. 2014, 6(232). 232ra52.
92. Ku K.B., Park E.H., Yum J., Kim J.A., Oh S.K., Seo S.H. Highly pathogenic avian influenza A(H5N8) virus from waterfowl, South Korea, 2014. Emerg. Infect. Dis. 2014, 20(9):1587-1588.
93. Kumlin U., Olofsson S., Dimock K., Arnberg N. Sialic acid tissue distribution and influenza virus tropism. Influenza Other Respir. Viruses 2008, 2(5):147-154.
94. Laddy D.J., Yan J., Kutzler M., Kobasa D., Kobinger G.P., Khan A.S., Greenhouse J., Sardesai N.Y., Draghia-Akli R., Weiner D.B. Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. PLoS One 2008, 3(6):e2517.
95. Lambert L.C., Fauci A.S. Influenza vaccines for the future. N. Engl. J. Med. 2010, 363(21):2036-2044.
96. Larsen G.L., Colasurdo G.N. Neural control mechanisms within airways: disruption by respiratory syncytial virus. J. Pediatr. 1999, 135(2, Part 2):21-27.
97. Leonard V.H., Hodge G., Reyes-Del Valle J., McChesney M.B., Cattaneo R. Measles virus selectively blind to signaling lymphocytic activation molecule (SLAM; CD150) is attenuated and induces strong adaptive immune responses in rhesus monkeys. J. Virol. 2010, 84(7):3413-3420.
98. Lewington J.H. Ferret Husbandry, Medicine and Surgery 2007, Elsevier Saunders, Edinburgh; New York. 2nd ed.
99. Li S., Liu C., Klimov A., Subbarao K., Perdue M.L., Mo D., Ji Y., Woods L., Hietala S., Bryant M. Recombinant influenza A virus vaccines for the pathogenic human A/Hong Kong/97 (H5N1) viruses. J. Infect. Dis. 1999, 179(5):1132-1138.
100. Li W., Moore M.J., Vasilieva N., Sui J., Wong S.K., Berne M.A., Somasundaran M., Sullivan J.L., Luzuriaga K., Greenough T.C., Choe H., Farzan M. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003, 426(6965):450-454.
101. Li Z., Sun X., Chen J., Liu X., Wisely S.M., Zhou Q., Renard J.P., Leno G.H., Engelhardt J.F. Cloned ferrets produced by somatic cell nuclear transfer. Dev. Biol. 2006, 293(2):439-448.
102. Lin J., Zhang J., Dong X., Fang H., Chen J., Su N., Gao Q., Zhang Z., Liu Y., Wang Z., Yang M., Sun R., Li C., Lin S., Ji M., Wang X., Wood J., Feng Z., Wang Y., Yin W. Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial. Lancet 2006, 368(9540):991-997.
103. Lin S.C., Lin Y.F., Chong P., Wu S.C. Broader neutralizing antibodies against H5N1 viruses using prime-boost immunization of hyperglycosylated hemagglutinin DNA and virus-like particles. PLoS One 2012, 7(6):e39075.
104. Linster M., van Boheemen S., de Graaf M., Schrauwen E.J., Lexmond P., Manz B., Bestebroer T.M., Baumann J., van Riel D., Rimmelzwaan G.F., Osterhaus A.D., Matrosovich M., Fouchier R.A., Herfst S. Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus. Cell 2014, 157(2):329-339.
105. Lipatov A.S., Kwon Y.K., Pantin-Jackwood M.J., Swayne D.E. Pathogenesis of H5N1 influenza virus infections in mice and ferret models differs according to respiratory tract or digestive system exposure. J. Infect. Dis. 2009, 199(5):717-725.
106. Lotz M.T., Peebles R.S. Mechanisms of respiratory syncytial virus modulation of airway immune responses. Curr. Allergy Asthma Rep. 2012, 12(5):380-387.
107. Luby S.P., Gurley E.S., Hossain M.J. Transmission of human infection with Nipah virus. Clin. Infect. Dis. 2009, 49(11):1743-1748.
108. Ludlow M., Rennick L.J., Nambulli S., de Swart R.L., Duprex W.P. Using the ferret model to study morbillivirus entry, spread, transmission and cross-species infection. Curr. Opin. Virol. 2014, 4:15-23.
109. MacPhail M., Schickli J.H., Tang R.S., Kaur J., Robinson C., Fouchier R.A., Osterhaus A.D., Spaete R.R., Haller A.A. Identification of small-animal and primate models for evaluation of vaccine candidates for human metapneumovirus (hMPV) and implications for hMPV vaccine design. J. Gen. Virol. 2004, 85(Part 6):1655-1663.
110. Mahmood K., Bright R.A., Mytle N., Carter D.M., Crevar C.J., Achenbach J.E., Heaton P.M., Tumpey T.M., Ross T.M. H5N1 VLP vaccine induced protection in ferrets against lethal challenge with highly pathogenic H5N1 influenza viruses. Vaccine 2008, 26(42):5393-5399.
111. Maines T.R., Belser J.A., Gustin K.M., van Hoeven N., Zeng H., Svitek N., von Messling V., Katz J.M., Tumpey T.M. Local innate immune responses and influenza virus transmission and virulence in ferrets. J. Infect. Dis. 2012, 205(3):474-485.
112. Maines T.R., Chen L.M., Belser J.A., Van Hoeven N., Smith E., Donis R.O., Tumpey T.M., Katz J.M. Multiple genes contribute to the virulent phenotype observed in ferrets of an H5N1 influenza virus isolated from Thailand in 2004. Virology 2011, 413(2):226-230.
113. Maines T.R., Chen L.M., Matsuoka Y., Chen H., Rowe T., Ortin J., Falcon A., Nguyen T.H., Mai le Q., Sedyaningsih E.R., Harun S., Tumpey T.M., Donis R.O., Cox N.J., Subbarao K., Katz J.M. Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model. Proc. Natl. Acad. Sci. USA 2006, 103(32):12121-12126.
114. Maines T.R., Jayaraman A., Belser J.A., Wadford D.A., Pappas C., Zeng H., Gustin K.M., Pearce M.B., Viswanathan K., Shriver Z.H., Raman R., Cox N.J., Sasisekharan R., Katz J.M., Tumpey T.M. Transmission and pathogenesis of swine-origin 2009A(H1N1) influenza viruses in ferrets and mice. Science 2009, 325(5939):484-487.
115. Marsh G.A., Virtue E.R., Smith I., Todd S., Arkinstall R., Frazer L., Monaghan P., Smith G.A., Broder C.C., Middleton D., Wang L.F. Recombinant Hendra viruses expressing a reporter gene retain pathogenicity in ferrets. Virol. J. 2013, 10:95.
116. Martina B.E., Haagmans B.L., Kuiken T., Fouchier R.A., Rimmelzwaan G.F., Van Amerongen G., Peiris J.S., Lim W., Osterhaus A.D. Virology: SARS virus infection of cats and ferrets. Nature 2003, 425(6961):915.
117. Mascoli C.C., Gower T.A., Capilupo F.A., Metzgar D.P. Further studies on the neonatal ferret model of infection and immunity to and attenuation of human parainfluenza viruses. Dev. Biol. Stand. 1976, 33:384-390.
118. Mascoli C.C., Metzgar D.P., Larson E.J., Fuscaldo A.A., Gower T.A. An animal model for studying infection and immunity to and attenuation of human parainfluenza viruses. Dev. Biol. Stand. 1975, 28:414-421.
119. Matrosovich M., Tuzikov A., Bovin N., Gambaryan A., Klimov A., Castrucci M.R., Donatelli I., Kawaoka Y. Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals. J. Virol. 2000, 74(18):8502-8512.
120. McCullers J.A., McAuley J.L., Browall S., Iverson A.R., Boyd K.L., Henriques Normark B. Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets. J. Infect. Dis. 2010, 202(8):1287-1295.
121. Meunier I., Embury-Hyatt C., Stebner S., Gray M., Bastien N., Li Y., Plummer F., Kobinger G.P., von Messling V. Virulence differences of closely related pandemic 2009 H1N1 isolates correlate with increased inflammatory responses in ferrets. Virology 2012, 422(1):125-131.
122. Middleton D., Pallister J., Klein R., Feng Y.R., Haining J., Arkinstall R., Frazer L., Huang J.A., Edwards N., Wareing M., Elhay M., Hashmi Z., Bingham J., Yamada M., Johnson D., White J., Foord A., Heine H.G., Marsh G.A., Broder C.C., Wang L.F. Hendra virus vaccine, a one health approach to protecting horse, human, and environmental health. Emerg. Infect. Dis. 2014, 20(3):372-379.
123. Mire C.E., Versteeg K.M., Cross R.W., Agans K.N., Fenton K.A., Whitt M.A., Geisbert T.W. Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease. Virol. J. 2013, 10:353.
124. Moore I.N., Lamirande E.W., Paskel M., Donahue D., Qin J., Subbarao K. Severity of clinical disease and pathology in ferrets experimentally infected with influenza viruses is influenced by inoculum volume. J. Virol. 2014, 88(23):13879-13891.
125. Muhlebach M.D., Mateo M., Sinn P.L., Prufer S., Uhlig K.M., Leonard V.H., Navaratnarajah C.K., Frenzke M., Wong X.X., Sawatsky B., Ramachandran S., McCray P.B., Cichutek K., von Messling V., Lopez M., Cattaneo R. Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Nature 2011, 480(7378):530-533.
126. Munster V.J., de Wit E., van den Brand J.M., Herfst S., Schrauwen E.J., Bestebroer T.M., van de Vijver D., Boucher C.A., Koopmans M., Rimmelzwaan G.F., Kuiken T., Osterhaus A.D., Fouchier R.A. Pathogenesis and transmission of swine-origin 2009A(H1N1) influenza virus in ferrets. Science 2009, 325(5939):481-483.
127. Nagata T., Lefor A.K., Hasegawa M., Ishii M. Favipiravir: a new medication for the ebola virus disease pandemic. Disaster Med. Public Health Prep. 2014, 1-3.
128. Nair H., Nokes D.J., Gessner B.D., Dherani M., Madhi S.A., Singleton R.J., O[U+05F3]Brien K.L., Roca A., Wright P.F., Bruce N., Chandran A., Theodoratou E., Sutanto A., Sedyaningsih E.R., Ngama M., Munywoki P.K., Kartasasmita C., Simoes E.A., Rudan I., Weber M.W., Campbell H. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 2010, 375(9725):1545-1555.
129. Nguyen H.T., Fry A.M., Gubareva L.V. Neuraminidase inhibitor resistance in influenza viruses and laboratory testing methods. Antivir. Ther. 2012, 17(1, Part B):159-173.
130. Nicholls J.M., Chan R.W., Russell R.J., Air G.M., Peiris J.S. Evolving complexities of influenza virus and its receptors. Trends Microbiol. 2008, 16(4):149-157.
131. Niezgoda M., Briggs D.J., Shaddock J., Dreesen D.W., Rupprecht C.E. Pathogenesis of experimentally induced rabies in domestic ferrets. Am. J. Vet. Res. 1997, 58(11):1327-1331.
132. Noyce R.S., Bondre D.G., Ha M.N., Lin L.T., Sisson G., Tsao M.S., Richardson C.D. Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus. PLoS Pathog. 2011, 7(8):e1002240.
133. O[U+05F3]Sullivan J.D., Allworth A.M., Paterson D.L., Snow T.M., Boots R., Gleeson L.J., Gould A.R., Hyatt A.D., Bradfield J. Fatal encephalitis due to novel paramyxovirus transmitted from horses. Lancet 1997, 349(9045):93-95.
134. Olson J.G., Rupprecht C., Rollin P.E., An U.S., Niezgoda M., Clemins T., Walston J., Ksiazek T.G. Antibodies to Nipah-like virus in bats (Pteropus lylei), Cambodia. Emerg. Infect. Dis. 2002, 8(9):987-988.
135. Onishi M., Kitano M., Taniguchi K., Homma T., Kobayashi M., Sato A., Coban C., Ishii K.J. Hemozoin is a potent adjuvant for hemagglutinin split vaccine without pyrogenicity in ferrets. Vaccine 2014, 32(25):3004-3009.
136. Palese P., Shaw ML. Orthomyxoviridae: the viruses and their replication. Knipe D.M., Howley P.M. (Eds.), Fields Virology 2007, Lippincott Williams, Philadelphia. 5th edition.
137. Pallister J., Middleton D., Crameri G., Yamada M., Klein R., Hancock T.J., Foord A., Shiell B., Michalski W., Broder C.C., Wang L.F. Chloroquine administration does not prevent Nipah virus infection and disease in ferrets. J. Virol. 2009, 83(22):11979-11982.
138. Pallister J., Middleton D., Wang L.F., Klein R., Haining J., Robinson R., Yamada M., White J., Payne J., Feng Y.R., Chan Y.P., Broder C.C. A recombinant Hendra virus G glycoprotein-based subunit vaccine protects ferrets from lethal Hendra virus challenge. Vaccine 2011, 29(34):5623-5630.
139. Pallister J.A., Klein R., Arkinstall R., Haining J., Long F., White J.R., Payne J., Feng Y.R., Wang L.F., Broder C.C., Middleton D. Vaccination of ferrets with a recombinant G glycoprotein subunit vaccine provides protection against Nipah virus disease for over 12 months. Virol. J. 2013, 10:237.
140. Parker L., Gilliland S.M., Minor P., Schepelmann S. Assessment of the ferret as an in vivo model for mumps virus infection. J. Gen. Virol. 2013, 94(Part 6):1200-1205.
141. Peiris J.S., Cheung C.Y., Leung C.Y., Nicholls J.M. Innate immune responses to influenza A H5N1: friend or foe?. Trends Immunol. 2009, 30(12):574-584.
142. Peiris J.S., Chu C.M., Cheng V.C., Chan K.S., Hung I.F., Poon L.L., Law K.I., Tang B.S., Hon T.Y., Chan C.S., Chan K.H., Ng J.S., Zheng B.J., Ng W.L., Lai R.W., Guan Y., Yuen K.Y. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 2003, 361(9371):1767-1772.
143. Peltola V.T., Boyd K.L., McAuley J.L., Rehg J.E., McCullers J.A. Bacterial sinusitis and otitis media following influenza virus infection in ferrets. Infect. Immun. 2006, 74(5):2562-2567.
144. Peng X., Alfoldi J., Gori K., Eisfeld A.J., Tyler S.R., Tisoncik-Go J., Brawand D., Law G.L., Skunca N., Hatta M., Gasper D.J., Kelly S.M., Chang J., Thomas M.J., Johnson J., Berlin A.M., Lara M., Russell P., Swofford R., Turner-Maier J., Young S., Hourlier T., Aken B., Searle S., Sun X., Yi Y., Suresh M., Tumpey T.M., Siepel A., Wisely S.M., Dessimoz C., Kawaoka Y., Birren B.W., Lindblad-Toh K., Di Palma F., Engelhardt J.F., Palermo R.E., Katze M.G. The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease. Nat. Biotechnol. 2014, 32(12):1250-1255.
145. Petsch B., Schnee M., Vogel A.B., Lange E., Hoffmann B., Voss D., Schlake T., Thess A., Kallen K.J., Stitz L., Kramps T. Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection. Nat. Biotechnol. 2012, 30(12):1210-1216.
146. Pillet S., Kobasa D., Meunier I., Gray M., Laddy D., Weiner D.B., von Messling V., Kobinger G.P. Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets. Vaccine 2011, 29(39):6793-6801.
147. Pillet S., von Messling V. Canine distemper virus selectively inhibits apoptosis progression in infected immune cells. J. Virol. 2009, 83(12):6279-6287.
148. Playford E.G., McCall B., Smith G., Slinko V., Allen G., Smith I., Moore F., Taylor C., Kung Y.H., Field H. Human Hendra virus encephalitis associated with equine outbreak, Australia, 2008. Emerg. Infect. Dis. 2010, 16(2):219-223.
149. Poland G.A., Sambhara S. Vaccines against influenza A (H5N1): evidence of progress. J. Infect. Dis. 2008, 198(5):629-631.
150. Prince G.A., Porter D.D. The pathogenesis of respiratory syncytial virus infection in infant ferrets. Am. J. Pathol. 1976, 82(2):339-352.
151. Pushko P., Pearce M.B., Ahmad A., Tretyakova I., Smith G., Belser J.A., Tumpey T.M. Influenza virus-like particle can accommodate multiple subtypes of hemagglutinin and protect from multiple influenza types and subtypes. Vaccine 2011, 29(35):5911-5918.
152. Raj V.S., Mou H., Smits S.L., Dekkers D.H., Muller M.A., Dijkman R., Muth D., Demmers J.A., Zaki A., Fouchier R.A., Thiel V., Drosten C., Rottier P.J., Osterhaus A.D., Bosch B.J., Haagmans B.L. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 2013, 495(7440):251-254.
153. Ramachandran A., Parisien J.P., Horvath C.M. STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition. J. Virol. 2008, 82(17):8330-8338.
154. Rao S.S., Kong W.P., Wei C.J., Van Hoeven N., Gorres J.P., Nason M., Andersen H., Tumpey T.M., Nabel G.J. Comparative efficacy of hemagglutinin, nucleoprotein, and matrix 2 protein gene-based vaccination against H5N1 influenza in mouse and ferret. PLoS One 2010, 5(3):e9812.
155. Richard M., Schrauwen E.J., de Graaf M., Bestebroer T.M., Spronken M.I., van Boheemen S., de Meulder D., Lexmond P., Linster M., Herfst S., Smith D.J., van den Brand J.M., Burke D.F., Kuiken T., Rimmelzwaan G.F., Osterhaus A.D., Fouchier R.A. Limited airborne transmission of H7N9 influenza A virus between ferrets. Nature 2013, 501(7468):560-563.
156. Rimmelzwaan G.F., Sutter G. Candidate influenza vaccines based on recombinant modified vaccinia virus Ankara. Expert Rev. Vaccines 2009, 8(4):447-454.
157. Robinson N.P., Venning L., Kyle H., Widdicombe J.G. Quantitation of the secretory cells of the ferret tracheobronchial tree. J. Anat. 1986, 145:173-188.
158. Rodgers L., Pabst L.J., Chaves S.S. Increasing uptake of live attenuated influenza vaccine among children in the United States, 2008-2014. Vaccine 2015, 33(1):22-24.
159. Rorke L.B., Fabiyi A., Elizan T.S., Sever J.L. Experimental cerebrovascular lesions in congenital and neonatal rubella-virus infections of ferrets. Lancet 1968, 2(7560):153-154.
160. Ross T.M., Mahmood K., Crevar C.J., Schneider-Ohrum K., Heaton P.M., Bright R.A. A trivalent virus-like particle vaccine elicits protective immune responses against seasonal influenza strains in mice and ferrets. PLoS One 2009, 4(6):e6032.
161. Rothlisberger A., Wiener D., Schweizer M., Peterhans E., Zurbriggen A., Plattet P. Two domains of the V protein of virulent canine distemper virus selectively inhibit STAT1 and STAT2 nuclear import. J. Virol. 2010, 84(13):6328-6343.
162. Rouxel R.N., Svitek N., von Messling V. A chimeric measles virus with canine distemper envelope protects ferrets from lethal distemper challenge. Vaccine 2009, 27(36):4961-4966.
163. Rowe T., Leon A.J., Crevar C.J., Carter D.M., Xu L., Ran L., Fang Y., Cameron C.M., Cameron M.J., Banner D., Ng D.C., Ran R., Weirback H.K., Wiley C.A., Kelvin D.J., Ross T.M. Modeling host responses in ferrets during A/California/07/2009 influenza infection. Virology 2010, 401(2):257-265.
164. Rudd P.A., Cattaneo R., von Messling V. Canine distemper virus uses both the anterograde and the hematogenous pathway for neuroinvasion. J. Virol. 2006, 80(19):9361-9370.
165. Rupprecht C.E., Gilbert J., Pitts R., Marshall K.R., Koprowski H. Evaluation of an inactivated rabies virus vaccine in domestic ferrets. J. Am. Vet. Med. Assoc. 1990, 196(10):1614-1616.
166. Rutigliano J.A., Doherty P.C., Franks J., Morris M.Y., Reynolds C., Thomas P.G. Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection. J. Immunol. Methods 2008, 336(1):71-77.
167. Sawatsky B., Wong X.X., Hinkelmann S., Cattaneo R., von Messling V. Canine distemper virus epithelial cell infection is required for clinical disease but not for immunosuppression. J. Virol. 2012, 86(7):3658-3666.
168. See R.H., Petric M., Lawrence D.J., Mok C.P., Rowe T., Zitzow L.A., Karunakaran K.P., Voss T.G., Brunham R.C., Gauldie J., Finlay B.B., Roper R.L. Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines. J. Gen. Virol. 2008, 89(Pt 9):2136-2146.
169. Sherrill A., Gorham J. Bone marrow hypoplasia associated with estrus in ferrets. Lab. Anim. Sci. 1985, 35(3):280-286.
170. Shinya K., Ebina M., Yamada S., Ono M., Kasai N., Kawaoka Y. Avian flu: influenza virus receptors in the human airway. Nature 2006, 440(7083):435-436.
171. Shinya K., Hamm S., Hatta M., Ito H., Ito T., Kawaoka Y. PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice. Virology 2004, 320(2):258-266.
172. Smith H., Sweet C. Lessons for human influenza from pathogenicity studies with ferrets. Rev. Infect. Dis. 1988, 10(1):56-75.
173. Smith W., Andrewes C.H., Laidlaw P.P. A virus obtained from influenza patients. Lancet 1933, 222:66.
174. Stevens J., Blixt O., Chen L.M., Donis R.O., Paulson J.C., Wilson I.A. Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity. J. Mol. Biol. 2008, 381(5):1382-1394.
175. Subbarao K., Luke C. H5N1 viruses and vaccines. PLoS Pathog. 2007, 3(3):e40.
176. Suguitan A.L., Cheng X., Wang W., Wang S., Jin H., Lu S. Influenza H5 hemagglutinin DNA primes the antibody response elicited by the live attenuated influenza A/Vietnam/1203/2004 vaccine in ferrets. PLoS One 2011, 6(7):e21942.
177. Suguitan A.L., McAuliffe J., Mills K.L., Jin H., Duke G., Lu B., Luke C.J., Murphy B., Swayne D.E., Kemble G., Subbarao K. Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets. PLoS Med. 2006, 3(9):e360.
178. Sun X., Sui H., Fisher J.T., Yan Z., Liu X., Cho H.J., Joo N.S., Zhang Y., Zhou W., Yi Y., Kinyon J.M., Lei-Butters D.C., Griffin M.A., Naumann P., Luo M., Ascher J., Wang K., Frana T., Wine J.J., Meyerholz D.K., Engelhardt J.F. Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis. J. Clin. Invest. 2010, 120(9):3149-3160.
179. Sutton T.C., Finch C., Shao H., Angel M., Chen H., Capua I., Cattoli G., Monne I., Perez D.R. Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets. J. Virol. 2014, 88(12):6623-6635.
180. Svitek N., Gerhauser I., Goncalves C., Grabski E., Doring M., Kalinke U., Anderson D.E., Cattaneo R., von Messling V. Morbillivirus control of the interferon response: relevance of STAT2 and mda5 but not STAT1 for canine distemper virus virulence in ferrets. J. Virol. 2014, 88(5):2941-2950.
181. Svitek N., Rudd P.A., Obojes K., Pillet S., von Messling V. Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction. Virology 2008, 376(1):53-59.
182. Svitek N., von Messling V. Early cytokine mRNA expression profiles predict Morbillivirus disease outcome in ferrets. Virology 2007, 362(2):404-410.
183. Sweet C., Hayden F.G., Jakeman K.J., Grambas S., Hay A.J. Virulence of rimantadine-resistant human influenza A (H3N2) viruses in ferrets. J. Infect. Dis. 1991, 164(5):969-972.
184. Tan C.T., Goh K.J., Wong K.T., Sarji S.A., Chua K.B., Chew N.K., Murugasu P., Loh Y.L., Chong H.T., Tan K.S., Thayaparan T., Kumar S., Jusoh M.R. Relapsed and late-onset Nipah encephalitis. Ann. Neurol. 2002, 51(6):703-708.
185. Tang L., González R., Dobrinski I. Germline modification of domestic animals. Anim. Reprod. 2015, 12(1):93-104.
186. Tatsuo H., Ono N., Tanaka K., Yanagi Y. SLAM (CDw150) is a cellular receptor for measles virus. Nature 2000, 406(6798):893-897.
187. Tatsuo H., Ono N., Yanagi Y. Morbilliviruses use signaling lymphocyte activation molecules (CD150) as cellular receptors. J. Virol. 2001, 75(13):5842-5850.
188. Taubenberger J.K., Reid A.H., Krafft A.E., Bijwaard K.E., Fanning T.G. Initial genetic characterization of the 1918 "Spanish" influenza virus. Science 1997, 275(5307):1793-1796.
189. ter Meulen J., Bakker A.B., van den Brink E.N., Weverling G.J., Martina B.E., Haagmans B.L., Kuiken T., de Kruif J., Preiser W., Spaan W., Gelderblom H.R., Goudsmit J., Osterhaus A.D. Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets. Lancet 2004, 363(9427):2139-2141.
190. To K.F., Chan P.K., Chan K.F., Lee W.K., Lam W.Y., Wong K.F., Tang N.L., Tsang D.N., Sung R.Y., Buckley T.A., Tam J.S., Cheng A.F. Pathology of fatal human infection associated with avian influenza A H5N1 virus. J. Med. Virol. 2001, 63(3):242-246.
191. Tong S., Li Y., Rivailler P., Conrardy C., Castillo D.A., Chen L.M., Recuenco S., Ellison J.A., Davis C.T., York I.A., Turmelle A.S., Moran D., Rogers S., Shi M., Tao Y., Weil M.R., Tang K., Rowe L.A., Sammons S., Xu X., Frace M., Lindblade K.A., Cox N.J., Anderson L.J., Rupprecht C.E., Donis R.O. A distinct lineage of influenza A virus from bats. Proc. Natl. Acad. Sci. USA 2012, 109(11):4269-4274.
192. Tong S., Zhu X., Li Y., Shi M., Zhang J., Bourgeois M., Yang H., Chen X., Recuenco S., Gomez J., Chen L.M., Johnson A., Tao Y., Dreyfus C., Yu W., McBride R., Carney P.J., Gilbert A.T., Chang J., Guo Z., Davis C.T., Paulson J.C., Stevens J., Rupprecht C.E., Holmes E.C., Wilson I.A., Donis R.O. New world bats harbor diverse influenza A viruses. PLoS Pathog. 2013, 9(10):e1003657.
193. Tretyakova I., Pearce M.B., Florese R., Tumpey T.M., Pushko P. Intranasal vaccination with H5, H7 and H9 hemagglutinins co-localized in a virus-like particle protects ferrets from multiple avian influenza viruses. Virology 2013, 442(1):67-73.
194. Tumpey T.M., Basler C.F., Aguilar P.V., Zeng H., Solorzano A., Swayne D.E., Cox N.J., Katz J.M., Taubenberger J.K., Palese P., Garcia-Sastre A. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 2005, 310(5745):77-80.
195. Tumpey T.M., Maines T.R., Van Hoeven N., Glaser L., Solorzano A., Pappas C., Cox N.J., Swayne D.E., Palese P., Katz J.M., Garcia-Sastre A. A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science 2007, 315(5812):655-659.
196. van den Brand J.M., Kreijtz J.H., Bodewes R., Stittelaar K.J., van Amerongen G., Kuiken T., Simon J., Fouchier R.A., Del Giudice G., Rappuoli R., Rimmelzwaan G.F., Osterhaus A.D. Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets. J. Virol. 2011, 85(6):2851-2858.
197. van den Brand J.M., Stittelaar K.J., van Amerongen G., Reperant L., de Waal L., Osterhaus A.D., Kuiken T. Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets. PLoS One 2012, 7(8):e42343.
198. van den Hoogen B.G., de Jong J.C., Groen J., Kuiken T., de Groot R., Fouchier R.A., Osterhaus A.D. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat. Med. 2001, 7(6):719-724.
199. van den Hoogen B.G., van Doornum G.J., Fockens J.C., Cornelissen J.J., Beyer W.E., de Groot R., Osterhaus A.D., Fouchier R.A. Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients. J. Infect. Dis. 2003, 188(10):1571-1577.
200. van Doremalen N., Miazgowicz K.L., Milne-Price S., Bushmaker T., Robertson S., Scott D., Kinne J., McLellan J.S., Zhu J., Munster V.J. Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4. J. Virol. 2014, 88(16):9220-9232.
201. van Riel D., Munster V.J., de Wit E., Rimmelzwaan G.F., Fouchier R.A., Osterhaus A.D., Kuiken T. Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals. Am. J. Pathol. 2007, 171(4):1215-1223.
202. von Messling V., Oezguen N., Zheng Q., Vongpunsawad S., Braun W., Cattaneo R. Nearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells. J. Virol. 2005, 79(9):5857-5862.
203. von Messling V., Springfeld C., Devaux P., Cattaneo R. A ferret model of canine distemper virus virulence and immunosuppression. J. Virol. 2003, 77(23):12579-12591.
204. Vos A., Muller T., Cox J., Neubert L., Fooks A.R. Susceptibility of ferrets (Mustela putorius furo) to experimentally induced rabies with European Bat Lyssaviruses (EBLV). J. Vet Med. B Infect. Dis. Vet Public Health 2004, 51(2):55-60.
205. Watanabe T., Kiso M., Fukuyama S., Nakajima N., Imai M., Yamada S., Murakami S., Yamayoshi S., Iwatsuki-Horimoto K., Sakoda Y., Takashita E., McBride R., Noda T., Hatta M., Imai H., Zhao D., Kishida N., Shirakura M., de Vries R.P., Shichinohe S., Okamatsu M., Tamura T., Tomita Y., Fujimoto N., Goto K., Katsura H., Kawakami E., Ishikawa I., Watanabe S., Ito M., Sakai-Tagawa Y., Sugita Y., Uraki R., Yamaji R., Eisfeld A.J., Zhong G., Fan S., Ping J., Maher E.A., Hanson A., Uchida Y., Saito T., Ozawa M., Neumann G., Kida H., Odagiri T., Paulson J.C., Hasegawa H., Tashiro M., Kawaoka Y. Characterization of H7N9 influenza A viruses isolated from humans. Nature 2013, 501(7468):551-555.
206. Weingartl H., Czub M., Czub S., Neufeld J., Marszal P., Gren J., Smith G., Jones S., Proulx R., Deschambault Y., Grudeski E., Andonov A., He R., Li Y., Copps J., Grolla A., Dick D., Berry J., Ganske S., Manning L., Cao J. Immunization with modified vaccinia virus Ankara-based recombinant vaccine against severe acute respiratory syndrome is associated with enhanced hepatitis in ferrets. J. Virol. 2004, 78(22):12672-12676.
207. Welter J., Taylor J., Tartaglia J., Paoletti E., Stephensen C.B. Vaccination against canine distemper virus infection in infant ferrets with and without maternal antibody protection, using recombinant attenuated poxvirus vaccines. J. Virol. 2000, 74(14):6358-6367.
208. Wong K.T., Robertson T., Ong B.B., Chong J.W., Yaiw K.C., Wang L.F., Ansford A.J., Tannenberg A. Human Hendra virus infection causes acute and relapsing encephalitis. Neuropathol. Appl. Neurobiol. 2009, 35(3):296-305.
209. Wu H., Peng X., Xu L., Jin C., Cheng L., Lu X., Xie T., Yao H., Wu N. Novel reassortant influenza A(H5N8) viruses in domestic ducks, eastern China. Emerg. Infect. Dis. 2014, 20(8):1315-1318.
210. Xu P., Huang Z., Gao X., Michel F.J., Hirsch G., Hogan R.J., Sakamoto K., Ho W., Wu J., He B. Infection of mice, ferrets, and rhesus macaques with a clinical mumps virus isolate. J. Virol. 2013, 87(14):8158-8168.
211. Xu Q., Chen Z., Cheng X., Xu L., Jin H. Evaluation of live attenuated H7N3 and H7N7 vaccine viruses for their receptor binding preferences, immunogenicity in ferrets and cross reactivity to the novel H7N9 virus. PLoS One 2013, 8(10):e76884.
212. Yager E.J., Stagnar C., Gopalakrishnan R., Fuller J.T., Fuller D.H. Optimizing particle-mediated epidermal delivery of an influenza DNA vaccine in ferrets. Methods Mol. Biol. 2013, 940:223-237.
213. Yen H.L., Lipatov A.S., Ilyushina N.A., Govorkova E.A., Franks J., Yilmaz N., Douglas A., Hay A., Krauss S., Rehg J.E., Hoffmann E., Webster R.G. Inefficient transmission of H5N1 influenza viruses in a ferret contact model. J. Virol. 2007, 81(13):6890-6898.
214. Young P.L., Halpin K., Selleck P.W., Field H., Gravel J.L., Kelly M.A., Mackenzie J.S. Serologic evidence for the presence in Pteropus bats of a paramyxovirus related to equine morbillivirus. Emerg. Infect. Dis. 1996, 2(3):239-240.
215. Zaki A.M., van Boheemen S., Bestebroer T.M., Osterhaus A.D., Fouchier R.A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 2012, 367(19):1814-1820.
216. Zamoto A., Taguchi F., Fukushi S., Morikawa S., Yamada Y.K. Identification of ferret ACE2 and its receptor function for SARS-coronavirus. Adv. Exp. Med. Biol. 2006, 581:519-522.