A trivalent virus-like particle vaccine elicits protective immune responses against seasonal influenza strains in mice and ferrets

PLoS ONE

Volumn 4, Issue 6, 2009, Pages

  Ross, Ted M ^a,b   Mahmood, Kutub ^c,d   Crevar, Corey J ^a   Schneider Ohrum, Kirsten ^a,b   Heaton, Penny M ^c   Bright, Rick A ^c,e  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c NOVAVAX INC   (United States)

^d Adamas Pharmaceuticals Inc   (United States)

^e PATH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INFLUENZA VACCINE; INFLUENZA VIRUS LIKE PARTICLE VACCINE; UNCLASSIFIED DRUG; INACTIVATED VACCINE; VIRUS LIKE PARTICLE VACCINE; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; CD8+ T LYMPHOCYTE; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS REACTION; DOSE RESPONSE; DRUG EFFICACY; FEMALE; FERRET; HEMAGGLUTINATION INHIBITION; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS B; MALE; MOUSE; NONHUMAN; VIRUS STRAIN; VIRUS TITRATION; ANIMAL; GENETIC ENGINEERING; GENETICS; HEMAGGLUTINATION TEST; HUMAN; IMMUNOLOGY; METHODOLOGY; ORTHOMYXOVIRUS; SEASON; SPECIES DIFFERENCE;

ANIMALIA; HEXAPODA; MUS; MUSTELA; ORTHOMYXOVIRIDAE; TRICHOMONAS VAGINALIS VIRUS;

ANIMALS; FEMALE; FERRETS; GENETIC ENGINEERING; HEMAGGLUTINATION TESTS; HUMANS; IMMUNITY, CELLULAR; IMMUNIZATION; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA B VIRUS; MALE; MICE; ORTHOMYXOVIRIDAE; SEASONS; SPECIES SPECIFICITY; VACCINES, INACTIVATED; VACCINES, VIRUS-LIKE PARTICLE; VIRAL PROTEINS;

EID: 67650330245     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006032     Document Type: Article

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