Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction

Virology

Volumn 376, Issue 1, 2008, Pages 53-59

  Svitek, Nicholas ^a   Rudd, Penny A ^a   Obojes, Karola ^a   Pillet, Stéphane ^a   von Messling, Veronika ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

Cytokine response; Ferret model; Human seasonal influenza strains; Influenza A; Innate immune response inhibition; Pathogenesis; Virus host interactions

Indexed keywords

INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FERRET; HISTOPATHOLOGY; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS A; INNATE IMMUNITY; INTERSTITIAL PNEUMONIA; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; VIRULENCE;

ANIMALS; BODY TEMPERATURE; BODY WEIGHT; FERRETS; GENE EXPRESSION PROFILING; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INTERFERONS; INTERLEUKIN-6; INTERLEUKIN-8; LUNG; MALE; MOLECULAR SEQUENCE DATA; ORTHOMYXOVIRIDAE INFECTIONS; SEASONS; SEVERITY OF ILLNESS INDEX;

ANIMALIA; MUSTELA;

EID: 43749104421     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.02.035     Document Type: Article

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