A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute Nipah virus infection

PLoS Pathogens

Volumn 5, Issue 10, 2009, Pages

  Bossart, Katharine N ^a,e   Zhu, Zhongyu ^b,c   Middleton, Deborah ^a   Klippel, Jessica ^a   Crameri, Gary ^a   Bingham, John ^a   McEachern, Jennifer A ^a   Green, Diane ^a   Hancock, Timothy J ^a   Chan, Yee Peng ^d   Hickey, Andrew C ^d   Dimitrov, Dimiter S ^b   Wang, Lin Fa ^a   Broder, Christopher C ^d  

^a CSIRO   (Australia)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSS REACTING ANTIBODY; G GLYCOPROTEIN; HUMAN MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY M102.4; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS PROTEIN; GLYCOPROTEIN; MONOCLONAL ANTIBODY; VIRUS ENVELOPE PROTEIN; VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG TARGETING; EXPOSURE; FERRET; HENIPAVIRUS; IN VIVO STUDY; LETHALITY; LUNG; NEUROLOGIC DISEASE; NIPAH VIRUS; NONHUMAN; PASSIVE IMMUNIZATION; PATHOGENESIS; PATHOLOGY; RESPIRATORY TRACT DISEASE; RNA VIRUS INFECTION; SPLEEN; SYSTEMIC VASCULITIS; VASCULAR TISSUE; VIRUS REPLICATION; ACUTE DISEASE; ANIMAL; DISEASE MODEL; HENIPAVIRUS INFECTION; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PATHOGENICITY; TISSUE DISTRIBUTION; VIRUS LOAD;

ANIMALIA; HENIPAVIRUS; MUSTELA; NIPAH VIRUS; PARAMYXOVIRIDAE; PTEROPUS;

ACUTE DISEASE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; DISEASE MODELS, ANIMAL; FERRETS; GLYCOPROTEINS; HENIPAVIRUS INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; NIPAH VIRUS; RNA, VIRAL; TISSUE DISTRIBUTION; VIRAL ENVELOPE PROTEINS; VIRAL LOAD;

EID: 73849092511     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000642     Document Type: Article

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