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Volumn 44, Issue , 2015, Pages 229-255

Structure Principles of CRISPR-Cas Surveillance and Effector Complexes

Author keywords

DNA interference; Prokaryote immunity; Ribonucleoprotein particles; RNA silencing

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; DNA; NUCLEIC ACID; PHOSPHATE; RNA; RIBONUCLEOPROTEIN;

EID: 84937431545     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-060414-033939     Document Type: Article
Times cited : (19)

References (96)
  • 1
    • 84908508061 scopus 로고    scopus 로고
    • Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
    • Anders C, Niewoehner O, Duerst A, Jinek M. 2014. Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease. Nature 513: 569-73
    • (2014) Nature , vol.513 , pp. 569-573
    • Anders, C.1    Niewoehner, O.2    Duerst, A.3    Jinek, M.4
  • 2
    • 84887864796 scopus 로고    scopus 로고
    • The Cmr complex: An RNA-guided endoribonuclease
    • Bailey S. 2013. The Cmr complex: An RNA-guided endoribonuclease. Biochem. Soc. Trans. 41: 1464-67
    • (2013) Biochem. Soc. Trans. , vol.41 , pp. 1464-1467
    • Bailey, S.1
  • 3
    • 34047118522 scopus 로고    scopus 로고
    • CRISPR provides acquired resistance against viruses in prokaryotes
    • Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, et al. 2007. CRISPR provides acquired resistance against viruses in prokaryotes. Science 315: 1709-12
    • (2007) Science , vol.315 , pp. 1709-1712
    • Barrangou, R.1    Fremaux, C.2    Deveau, H.3    Richards, M.4    Boyaval, P.5
  • 4
    • 84862657238 scopus 로고    scopus 로고
    • CRISPR: New horizons in phage resistance and strain identification
    • Barrangou R, Horvath P. 2012. CRISPR: new horizons in phage resistance and strain identification. Annu. Rev. Food Sci. Technol. 3: 143-62
    • (2012) Annu. Rev. Food Sci. Technol. , vol.3 , pp. 143-162
    • Barrangou, R.1    Horvath, P.2
  • 5
    • 84899134190 scopus 로고    scopus 로고
    • CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity
    • Barrangou R, Marraffini LA. 2014. CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity. Mol. Cell 54: 234-44
    • (2014) Mol. Cell , vol.54 , pp. 234-244
    • Barrangou, R.1    Marraffini, L.A.2
  • 6
    • 84915828062 scopus 로고    scopus 로고
    • Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4
    • Benda C, Ebert J, Scheltema RA, SchillerHB, Baumgärtner M, et al. 2014. Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4. Mol. Cell 56: 43-54
    • (2014) Mol. Cell , vol.56 , pp. 43-54
    • Benda, C.1    Ebert, J.2    Scheltema, R.A.3    Schiller, H.B.4    Baumgärtner, M.5
  • 7
    • 23844505202 scopus 로고    scopus 로고
    • Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
    • Bolotin A, Quinquis B, Sorokin A, Ehrlich SD. 2005. Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin. Microbiology 151: 2551-61
    • (2005) Microbiology , vol.151 , pp. 2551-2561
    • Bolotin, A.1    Quinquis, B.2    Sorokin, A.3    Ehrlich, S.D.4
  • 9
    • 84903465255 scopus 로고    scopus 로고
    • The three major types of CRISPRCas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus
    • Carte J, Christopher RT, Smith JT, Olson S, Barrangou R, et al. 2014. The three major types of CRISPRCas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus. Mol. Microbiol. 93: 98-112
    • (2014) Mol. Microbiol. , vol.93 , pp. 98-112
    • Carte, J.1    Christopher, R.T.2    Smith, J.T.3    Olson, S.4    Barrangou, R.5
  • 10
    • 58049191229 scopus 로고    scopus 로고
    • Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes
    • Carte J, Wang R, Li H, Terns RM, Terns MP. 2008. Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes. Genes Dev. 22: 3489-96
    • (2008) Genes Dev. , vol.22 , pp. 3489-3496
    • Carte, J.1    Wang, R.2    Li, H.3    Terns, R.M.4    Terns, M.P.5
  • 12
    • 79953250082 scopus 로고    scopus 로고
    • CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
    • Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, et al. 2011. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471: 602-7
    • (2011) Nature , vol.471 , pp. 602-607
    • Deltcheva, E.1    Chylinski, K.2    Sharma, C.M.3    Gonzales, K.4    Chao, Y.5
  • 13
    • 38949123143 scopus 로고    scopus 로고
    • Phage response to CRISPRencoded resistance in Streptococcus thermophilus
    • Deveau H, Barrangou R, Garneau JE, Labonte J, Fremaux C, et al. 2008. Phage response to CRISPRencoded resistance in Streptococcus thermophilus. J. Bacteriol. 190: 1390-400
    • (2008) J. Bacteriol. , vol.190 , pp. 1390-1400
    • Deveau, H.1    Barrangou, R.2    Garneau, J.E.3    Labonte, J.4    Fremaux, C.5
  • 14
    • 84921540377 scopus 로고    scopus 로고
    • Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation
    • Doench JG, Hartenian E, Graham DB, Tothova Z, Hegde M, et al. 2014. Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation. Nat. Biotechnol. 32: 1262-67
    • (2014) Nat. Biotechnol. , vol.32 , pp. 1262-1267
    • Doench, J.G.1    Hartenian, E.2    Graham, D.B.3    Tothova, Z.4    Hegde, M.5
  • 16
    • 84895832944 scopus 로고    scopus 로고
    • Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
    • Fonfara I, LeRhun A, ChylinskiK, MakarovaKS, Lecrivain AL, et al. 2014. Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems. Nucleic Acids Res. 42: 2577-90
    • (2014) Nucleic Acids Res. , vol.42 , pp. 2577-2590
    • Fonfara, I.1    Lerhun, A.2    Chylinski, K.3    Makarova, K.S.4    Lecrivain, A.L.5
  • 17
    • 84880570576 scopus 로고    scopus 로고
    • High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
    • Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, et al. 2013. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 31: 822-26
    • (2013) Nat. Biotechnol. , vol.31 , pp. 822-826
    • Fu, Y.1    Foden, J.A.2    Khayter, C.3    Maeder, M.L.4    Reyon, D.5
  • 18
    • 78149261827 scopus 로고    scopus 로고
    • The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
    • Garneau JE, Dupuis ME, Villion M, Romero DA, Barrangou R, et al. 2011. The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature 468: 67-71
    • (2011) Nature , vol.468 , pp. 67-71
    • Garneau, J.E.1    Dupuis, M.E.2    Villion, M.3    Romero, D.A.4    Barrangou, R.5
  • 19
    • 84866859751 scopus 로고    scopus 로고
    • Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
    • Gasiunas G, Barrangou R, Horvath P, Siksnys V. 2012. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. PNAS 109: E2579-86
    • (2012) PNAS , vol.109 , pp. E2579-E2586
    • Gasiunas, G.1    Barrangou, R.2    Horvath, P.3    Siksnys, V.4
  • 20
    • 84887018028 scopus 로고    scopus 로고
    • RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing
    • Gasiunas G, Siksnys V. 2013. RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing? Trends Microbiol. 21: 562-67
    • (2013) Trends Microbiol , vol.21 , pp. 562-567
    • Gasiunas, G.1    Siksnys, V.2
  • 21
    • 84892804564 scopus 로고    scopus 로고
    • Molecular mechanisms of CRISPR-mediated microbial immunity
    • Gasiunas G, Sinkunas T, Siksnys V. 2014. Molecular mechanisms of CRISPR-mediated microbial immunity. Cell. Molec. Life Sci. 71: 449-65
    • (2014) Cell. Molec. Life Sci. , vol.71 , pp. 449-465
    • Gasiunas, G.1    Sinkunas, T.2    Siksnys, V.3
  • 23
    • 84908456823 scopus 로고    scopus 로고
    • Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting
    • Goldberg GW, Jiang W, Bikard D, Marraffini LA. 2014. Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting. Nature 514: 633-37
    • (2014) Nature , vol.514 , pp. 633-637
    • Goldberg, G.W.1    Jiang, W.2    Bikard, D.3    Marraffini, L.A.4
  • 24
    • 79953244160 scopus 로고    scopus 로고
    • Microbiology: Dicing defence in bacteria
    • Gottesman S. 2011. Microbiology: dicing defence in bacteria. Nature 471: 588-89
    • (2011) Nature , vol.471 , pp. 588-589
    • Gottesman, S.1
  • 25
    • 34248400310 scopus 로고    scopus 로고
    • A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes
    • Haft DH, Selengut J, Mongodin EF, Nelson KE. 2005. A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. PLOS Comput. Biol. 1: e60
    • (2005) PLOS Comput. Biol. , vol.1 , pp. e60
    • Haft, D.H.1    Selengut, J.2    Mongodin, E.F.3    Nelson, K.E.4
  • 26
    • 84908431900 scopus 로고    scopus 로고
    • Target RNA capture and cleavage by the Cmr type III-B CRISPR-Cas effector complex
    • Hale CR, Cocozaki A, Li H, Terns RM, Terns MP. 2014. Target RNA capture and cleavage by the Cmr type III-B CRISPR-Cas effector complex. Genes Dev. 28: 2432-43
    • (2014) Genes Dev. , vol.28 , pp. 2432-2443
    • Hale, C.R.1    Cocozaki, A.2    Li, H.3    Terns, R.M.4    Terns, M.P.5
  • 27
    • 70449753811 scopus 로고    scopus 로고
    • RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex
    • Hale CR, Zhao P, Olson S, Duff MO, Graveley BR, et al. 2009. RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Cell 139: 945-56
    • (2009) Cell , vol.139 , pp. 945-956
    • Hale, C.R.1    Zhao, P.2    Olson, S.3    Duff, M.O.4    Graveley, B.R.5
  • 28
    • 84855475577 scopus 로고    scopus 로고
    • Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site
    • Hatoum-Aslan A, Maniv I, Marraffini LA. 2011. Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site. PNAS 108: 21218-22
    • (2011) PNAS , vol.108 , pp. 21218-21222
    • Hatoum-Aslan, A.1    Maniv, I.2    Marraffini, L.A.3
  • 29
    • 84884765703 scopus 로고    scopus 로고
    • A ruler protein in a complex for antiviral defense determines the length of small interfering CRISPR RNAs
    • Hatoum-Aslan A, Samai P, Maniv I, Jiang W, Marraffini LA. 2013. A ruler protein in a complex for antiviral defense determines the length of small interfering CRISPR RNAs. J. Biol. Chem. 288: 27888-97
    • (2013) J. Biol. Chem. , vol.288 , pp. 27888-27897
    • Hatoum-Aslan, A.1    Samai, P.2    Maniv, I.3    Jiang, W.4    Marraffini, L.A.5
  • 30
    • 77956498326 scopus 로고    scopus 로고
    • Sequence-and structure-specific RNA processing by a CRISPR endonuclease
    • Haurwitz RE, Jinek M, Wiedenheft B, Zhou K, Doudna JA. 2010. Sequence-and structure-specific RNA processing by a CRISPR endonuclease. Science 329: 1355-58
    • (2010) Science , vol.329 , pp. 1355-1358
    • Haurwitz, R.E.1    Jinek, M.2    Wiedenheft, B.3    Zhou, K.4    Doudna, J.A.5
  • 31
    • 84885344825 scopus 로고    scopus 로고
    • Same same but different: New structural insight into CRISPR-Cas complexes
    • Heidrich N, Vogel J. 2013. Same same but different: new structural insight into CRISPR-Cas complexes. Mol. Cell 52: 4-7
    • (2013) Mol. Cell , vol.52 , pp. 4-7
    • Heidrich, N.1    Vogel, J.2
  • 32
    • 84924740446 scopus 로고    scopus 로고
    • Cutting it close: CRISPR-associated endoribonuclease structure and function
    • HochstrasserML, Doudna JA. 2015. Cutting it close: CRISPR-associated endoribonuclease structure and function. Trends Biochem. Sci. 40: 58-66
    • (2015) Trends Biochem. Sci. , vol.40 , pp. 58-66
    • Hochstrasser, M.L.1    Doudna, J.A.2
  • 33
    • 84899794031 scopus 로고    scopus 로고
    • CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
    • Hochstrasser ML, Taylor DW, Bhat P, Guegler CK, Sternberg SH, et al. 2014. CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference. PNAS 111: 6618-23
    • (2014) PNAS , vol.111 , pp. 6618-6623
    • Hochstrasser, M.L.1    Taylor, D.W.2    Bhat, P.3    Guegler, C.K.4    Sternberg, S.H.5
  • 34
    • 23944441091 scopus 로고    scopus 로고
    • New insights in the molecular biology and physiology of Streptococcus thermophilus revealed by comparative genomics
    • Hols P, Hancy F, Fontaine L, Grossiord B, Prozzi D, et al. 2005. New insights in the molecular biology and physiology of Streptococcus thermophilus revealed by comparative genomics. FEMS Microbiol. Rev. 29: 435-63
    • (2005) FEMS Microbiol. Rev. , vol.29 , pp. 435-463
    • Hols, P.1    Hancy, F.2    Fontaine, L.3    Grossiord, B.4    Prozzi, D.5
  • 35
    • 74249095519 scopus 로고    scopus 로고
    • CRISPR/Cas, the immune system of bacteria and archaea
    • Horvath P, Barrangou R. 2010. CRISPR/Cas, the immune system of bacteria and archaea. Science 327: 167-70
    • (2010) Science , vol.327 , pp. 167-170
    • Horvath, P.1    Barrangou, R.2
  • 36
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR-Cas9 for genome engineering
    • Hsu PD, Lander ES, Zhang F. 2014. Development and applications of CRISPR-Cas9 for genome engineering. Cell 157: 1262-78
    • (2014) Cell , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 37
    • 84921996108 scopus 로고    scopus 로고
    • Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation
    • Huo Y, Nam KH, Ding F, Lee H, Wu L, et al. 2014. Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nature Struct. Mol. Biol. 21: 771-77
    • (2014) Nature Struct. Mol. Biol. , vol.21 , pp. 771-777
    • Huo, Y.1    Nam, K.H.2    Ding, F.3    Lee, H.4    Wu, L.5
  • 38
    • 84907208955 scopus 로고    scopus 로고
    • Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli
    • Jackson RN, Golden SM, van Erp PB, Carter J, Westra ER, et al. 2014. Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli. Science 345: 1473-79
    • (2014) Science , vol.345 , pp. 1473-1479
    • Jackson, R.N.1    Golden, S.M.2    Van Erp, P.B.3    Carter, J.4    Westra, E.R.5
  • 40
  • 41
    • 84893157352 scopus 로고    scopus 로고
    • Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
    • JinekM, Jiang F, Taylor DW, Sternberg SH, Kaya E, et al. 2014. Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science 343: 1247997
    • (2014) Science , vol.343 , pp. 1247997
    • Jinek, M.1    Jiang, F.2    Taylor, D.W.3    Sternberg, S.H.4    Kaya, E.5
  • 42
    • 84866340552 scopus 로고    scopus 로고
    • Repression of bacterial lipoprotein production by Francisella novicida facilitates evasion of innate immune recognition
    • Jones CL, Sampson TR, Nakaya HI, Pulendran B, Weiss DS. 2012. Repression of bacterial lipoprotein production by Francisella novicida facilitates evasion of innate immune recognition. Cell. Microbiol. 14: 1531-43
    • (2012) Cell. Microbiol. , vol.14 , pp. 1531-1543
    • Jones, C.L.1    Sampson, T.R.2    Nakaya, H.I.3    Pulendran, B.4    Weiss, D.S.5
  • 44
    • 35748974534 scopus 로고    scopus 로고
    • Evolutionary conservation of sequence and secondary structures in CRISPR repeats
    • Kunin V, Sorek R, Hugenholtz P. 2007. Evolutionary conservation of sequence and secondary structures in CRISPR repeats. Genome Biol. 8: R61
    • (2007) Genome Biol. , vol.8 , pp. R61
    • Kunin, V.1    Sorek, R.2    Hugenholtz, P.3
  • 45
    • 84920939515 scopus 로고    scopus 로고
    • Structural principles of CRISPR RNA processing
    • Li H. 2015. Structural principles of CRISPR RNA processing. Structure 23: 13-20
    • (2015) Structure , vol.23 , pp. 13-20
    • Li, H.1
  • 46
    • 79958754524 scopus 로고    scopus 로고
    • Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE)
    • Lintner NG, Kerou M, Brumfield SK, Graham S, Liu H, et al. 2011. Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE). J. Biol. Chem. 286: 21643-56
    • (2011) J. Biol. Chem. , vol.286 , pp. 21643-21656
    • Lintner, N.G.1    Kerou, M.2    Brumfield, S.K.3    Graham, S.4    Liu, H.5
  • 47
    • 79960554003 scopus 로고    scopus 로고
    • Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems
    • Makarova KS, Aravind L, Wolf YI, Koonin EV. 2011. Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems. Biol. Direct 6: 38
    • (2011) Biol. Direct , vol.6 , pp. 38
    • Makarova, K.S.1    Aravind, L.2    Wolf, Y.I.3    Koonin, E.V.4
  • 48
    • 34248374277 scopus 로고    scopus 로고
    • Aputative RNA-interference-based immune system in prokaryotes: Computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action
    • Makarova KS, GrishinNV, Shabalina SA, Wolf YI, Koonin EV. 2006. Aputative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action. Biol. Direct 1: 7
    • (2006) Biol. Direct , vol.1 , pp. 7
    • Makarova, K.S.1    Grishin, N.V.2    Shabalina, S.A.3    Wolf, Y.I.4    Koonin, E.V.5
  • 50
    • 84887971081 scopus 로고    scopus 로고
    • The basic building blocks and evolution of CRISPR-Cas systems
    • Makarova KS, Wolf YI, Koonin EV. 2013. The basic building blocks and evolution of CRISPR-Cas systems. Biochem. Soc. Trans. 41: 1392-400
    • (2013) Biochem. Soc. Trans. , vol.41 , pp. 1392-1400
    • Makarova, K.S.1    Wolf, Y.I.2    Koonin, E.V.3
  • 51
    • 84888781186 scopus 로고    scopus 로고
    • RepurposingCRISPR/Cas9 for in situ functional assays
    • Malina A, Mills JR, Cencic R, Yan Y, Fraser J, et al. 2013. RepurposingCRISPR/Cas9 for in situ functional assays. Genes Dev. 27: 2602-14
    • (2013) Genes Dev. , vol.27 , pp. 2602-2614
    • Malina, A.1    Mills, J.R.2    Cencic, R.3    Yan, Y.4    Fraser, J.5
  • 52
    • 57849137502 scopus 로고    scopus 로고
    • CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA
    • Marraffini LA, Sontheimer EJ. 2008. CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science 322: 1843-45
    • (2008) Science , vol.322 , pp. 1843-1845
    • Marraffini, L.A.1    Sontheimer, E.J.2
  • 53
    • 77249170201 scopus 로고    scopus 로고
    • CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea
    • Marraffini LA, Sontheimer EJ. 2010. CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea. Nat. Rev. Genet. 11: 181-90
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 181-190
    • Marraffini, L.A.1    Sontheimer, E.J.2
  • 54
  • 55
    • 16444385662 scopus 로고    scopus 로고
    • Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
    • Mojica FJM, Déz-Villaseñor C, Garcá-Martnez J, Soria E. 2005. Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements. J. Mol. Evol. 60: 174-82
    • (2005) J. Mol. Evol. , vol.60 , pp. 174-182
    • Mojica, F.J.M.1    Déz-Villaseñor, C.2    Garcá-Martnez, J.3    Soria, E.4
  • 56
    • 80052400382 scopus 로고    scopus 로고
    • Structural and biochemical analysis of nuclease domain of clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 3 (Cas3)
    • Mulepati S, Bailey S. 2011. Structural and biochemical analysis of nuclease domain of clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 3 (Cas3). J. Biol. Chem. 286: 31896-903
    • (2011) J. Biol. Chem. , vol.286 , pp. 31896-31903
    • Mulepati, S.1    Bailey, S.2
  • 57
    • 84907204893 scopus 로고    scopus 로고
    • Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target
    • Mulepati S, Héroux A, Bailey S. 2014. Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target. Science 345: 1479-84
    • (2014) Science , vol.345 , pp. 1479-1484
    • Mulepati, S.1    Héroux, A.2    Bailey, S.3
  • 58
    • 84865704094 scopus 로고    scopus 로고
    • Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system
    • Nam KH, Haitjema C, Liu X, Ding F, Wang H, et al. 2012. Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system. Structure 20: 1574-84
    • (2012) Structure , vol.20 , pp. 1574-1584
    • Nam, K.H.1    Haitjema, C.2    Liu, X.3    Ding, F.4    Wang, H.5
  • 59
    • 84896733529 scopus 로고    scopus 로고
    • Crystal structure of Cas9 in complex with guide RNA and target DNA
    • Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, et al. 2014. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell 156: 935-49
    • (2014) Cell , vol.156 , pp. 935-949
    • Nishimasu, H.1    Ran, F.A.2    Hsu, P.D.3    Konermann, S.4    Shehata, S.I.5
  • 61
    • 84861357119 scopus 로고    scopus 로고
    • Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax
    • Plagens A, Tjaden B, Hagemann A, Randau L, Hensel R. 2012. Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax. J. Bacteriol. 194: 2491-500
    • (2012) J. Bacteriol. , vol.194 , pp. 2491-2500
    • Plagens, A.1    Tjaden, B.2    Hagemann, A.3    Randau, L.4    Hensel, R.5
  • 62
    • 15844390228 scopus 로고    scopus 로고
    • CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies
    • Pourcel C, Salvignol G, Vergnaud G. 2005. CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. Microbiology 151: 653-63
    • (2005) Microbiology , vol.151 , pp. 653-663
    • Pourcel, C.1    Salvignol, G.2    Vergnaud, G.3
  • 63
    • 77949398275 scopus 로고    scopus 로고
    • Identification and characterization of E. Coli CRISPR-cas promoters and their silencing by H-NS
    • Pul U, Wurm R, Arslan Z, Geissen R, Hofmann N, Wagner R. 2010. Identification and characterization of E. Coli CRISPR-cas promoters and their silencing by H-NS. Molec. Microbiol. 75: 1495-512
    • (2010) Molec. Microbiol. , vol.75 , pp. 1495-1512
    • Pul, U.1    Wurm, R.2    Arslan, Z.3    Geissen, R.4    Hofmann, N.5    Wagner, R.6
  • 64
    • 84915825854 scopus 로고    scopus 로고
    • Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex
    • Ramia NF, Spilman M, Tang L, Shao Y, Elmore J, et al. 2014. Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex. Cell Rep. 9: 1610-17
    • (2014) Cell Rep. , vol.9 , pp. 1610-1617
    • Ramia, N.F.1    Spilman, M.2    Tang, L.3    Shao, Y.4    Elmore, J.5
  • 65
  • 66
    • 84879584456 scopus 로고    scopus 로고
    • CRISPR interference: A structural perspective
    • Reeks J, Naismith JH, White MF. 2013. CRISPR interference: A structural perspective. Biochem. J. 453: 155-66
    • (2013) Biochem. J. , vol.453 , pp. 155-166
    • Reeks, J.1    Naismith, J.H.2    White, M.F.3
  • 67
    • 84877757610 scopus 로고    scopus 로고
    • Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing
    • Reeks J, Sokolowski RD, Graham S, Liu H, Naismith JH, White MF. 2013. Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing. Biochem. J. 452: 223-30
    • (2013) Biochem. J. , vol.452 , pp. 223-230
    • Reeks, J.1    Sokolowski, R.D.2    Graham, S.3    Liu, H.4    Naismith, J.H.5    White, M.F.6
  • 68
    • 84868111481 scopus 로고    scopus 로고
    • Characterization ofCRISPR RNA processing in Clostridium thermocellum and Methanococcus maripaludis
    • RichterH, Zoephel J, Schermuly J, MaticzkaD, Backofen R, Randau L. 2012. Characterization ofCRISPR RNA processing in Clostridium thermocellum and Methanococcus maripaludis. Nucleic Acids Res. 40: 9887-96
    • (2012) Nucleic Acids Res. , vol.40 , pp. 9887-9896
    • Richter, H.1    Zoephel, J.2    Schermuly, J.3    Maticzka, D.4    Backofen, R.5    Randau, L.6
  • 69
    • 84885336337 scopus 로고    scopus 로고
    • Structure of the CRISPR interference complex CSM reveals key similarities with Cascade
    • Rouillon C, Zhou M, Zhang J, Politis A, Beilsten-Edmands V, et al. 2013. Structure of the CRISPR interference complex CSM reveals key similarities with Cascade. Mol. Cell 52: 124-34
    • (2013) Mol. Cell , vol.52 , pp. 124-134
    • Rouillon, C.1    Zhou, M.2    Zhang, J.3    Politis, A.4    Beilsten-Edmands, V.5
  • 70
    • 84877782955 scopus 로고    scopus 로고
    • A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
    • Sampson TR, Saroj SD, Llewellyn AC, Tzeng Y-L, Weiss DS. 2013. A CRISPR/Cas system mediates bacterial innate immune evasion and virulence. Nature 497: 254-57
    • (2013) Nature , vol.497 , pp. 254-257
    • Sampson, T.R.1    Saroj, S.D.2    Llewellyn, A.C.3    Tzeng, Y.-L.4    Weiss, D.S.5
  • 71
    • 84900314611 scopus 로고    scopus 로고
    • CRISPR-Cas systems for editing, regulating and targeting genomes
    • Sander JD, Joung JK. 2014. CRISPR-Cas systems for editing, regulating and targeting genomes. Nat. Biotechnol. 32: 347-55
    • (2014) Nat. Biotechnol. , vol.32 , pp. 347-355
    • Sander, J.D.1    Joung, J.K.2
  • 72
    • 79958825675 scopus 로고    scopus 로고
    • An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3
    • Sashital DG, JinekM, Doudna JA. 2011. An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3. Nat. Struct. Molec. Biol. 18: 680-87
    • (2011) Nat. Struct. Molec. Biol. , vol.18 , pp. 680-687
    • Sashital, D.G.1    Jinek, M.2    Doudna, J.A.3
  • 73
    • 79959963663 scopus 로고    scopus 로고
    • Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
    • Semenova E, Jore MM, Datsenko KA, Semenova A, Westra ER, et al. 2011. Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence. PNAS 108: 10098-103
    • (2011) PNAS , vol.108 , pp. 10098-10103
    • Semenova, E.1    Jore, M.M.2    Datsenko, K.A.3    Semenova, A.4    Westra, E.R.5
  • 74
    • 84874930818 scopus 로고    scopus 로고
    • Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6
    • Shao Y, Li H. 2013. Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6. Structure 21: 385-93
    • (2013) Structure , vol.21 , pp. 385-393
    • Shao, Y.1    Li, H.2
  • 75
    • 84873571066 scopus 로고    scopus 로고
    • In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus
    • Sinkunas T, Gasiunas G, Waghmare SP, Dickman MJ, Barrangou R, et al. 2013. In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus. EMBO J. 32: 385-94
    • (2013) EMBO J. , vol.32 , pp. 385-394
    • Sinkunas, T.1    Gasiunas, G.2    Waghmare, S.P.3    Dickman, M.J.4    Barrangou, R.5
  • 76
    • 84903202938 scopus 로고    scopus 로고
    • Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system
    • Sokolowski RD, Graham S, White MF. 2014. Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system. Nucleic Acids Res. 42: 6532-41
    • (2014) Nucleic Acids Res. , vol.42 , pp. 6532-6541
    • Sokolowski, R.D.1    Graham, S.2    White, M.F.3
  • 77
    • 84878936806 scopus 로고    scopus 로고
    • CRISPR-mediated adaptive immune systems in bacteria and archaea
    • Sorek R, Lawrence CM, Wiedenheft B. 2013. CRISPR-mediated adaptive immune systems in bacteria and archaea. Annu. Rev. Biochem. 82: 237-66
    • (2013) Annu. Rev. Biochem. , vol.82 , pp. 237-266
    • Sorek, R.1    Lawrence, C.M.2    Wiedenheft, B.3
  • 78
    • 84885355637 scopus 로고    scopus 로고
    • Structure of an RNA silencing complex of the CRISPR-Cas immune system
    • Spilman M, Cocozaki A, Hale C, Shao Y, Ramia N, et al. 2013. Structure of an RNA silencing complex of the CRISPR-Cas immune system. Mol. Cell 52: 146-52
    • (2013) Mol. Cell , vol.52 , pp. 146-152
    • Spilman, M.1    Cocozaki, A.2    Hale, C.3    Shao, Y.4    Ramia, N.5
  • 79
    • 84885334898 scopus 로고    scopus 로고
    • Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus
    • Staals RHJ, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, et al. 2013. Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus. Mol. Cell 52: 135-45
    • (2013) Mol. Cell , vol.52 , pp. 135-145
    • Staals, R.H.J.1    Agari, Y.2    Maki-Yonekura, S.3    Zhu, Y.4    Taylor, D.W.5
  • 80
    • 84912066885 scopus 로고    scopus 로고
    • RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus
    • Staals RHJ, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, et al. 2014. RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus. Mol. Cell 56: 518-30
    • (2014) Mol. Cell , vol.56 , pp. 518-530
    • Staals, R.H.J.1    Zhu, Y.2    Taylor, D.W.3    Kornfeld, J.E.4    Sharma, K.5
  • 81
    • 84858659496 scopus 로고    scopus 로고
    • Mechanism of substrate selection by a highly specific CRISPR endoribonuclease
    • Sternberg SH, Haurwitz RE, Doudna JA. 2012. Mechanism of substrate selection by a highly specific CRISPR endoribonuclease. RNA 18: 661-72
    • (2012) RNA , vol.18 , pp. 661-672
    • Sternberg, S.H.1    Haurwitz, R.E.2    Doudna, J.A.3
  • 83
    • 33644756595 scopus 로고    scopus 로고
    • Homing endonuclease structure and function
    • Stoddard BL. 2005. Homing endonuclease structure and function. Q. Rev. Biophys. 38: 49-95
    • (2005) Q. Rev. Biophys. , vol.38 , pp. 49-95
    • Stoddard, B.L.1
  • 84
  • 85
    • 84896731736 scopus 로고    scopus 로고
    • CRISPR-based technologies: Prokaryotic defense weapons repurposed
    • Terns RM, Terns MP. 2014. CRISPR-based technologies: Prokaryotic defense weapons repurposed. Trends Genet. 30: 111-18
    • (2014) Trends Genet. , vol.30 , pp. 111-118
    • Terns, R.M.1    Terns, M.P.2
  • 87
    • 79551694059 scopus 로고    scopus 로고
    • Interaction of the Cas6 riboendonuclease with CRISPR RNAs: Recognition and cleavage
    • Wang R, Preamplume G, Terns MP, Terns RM, Li H. 2011. Interaction of the Cas6 riboendonuclease with CRISPR RNAs: recognition and cleavage. Structure 19: 257-64
    • (2011) Structure , vol.19 , pp. 257-264
    • Wang, R.1    Preamplume, G.2    Terns, M.P.3    Terns, R.M.4    Li, H.5
  • 89
    • 84861996069 scopus 로고    scopus 로고
    • CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3
    • Westra ER, van Erp PBG, Künne T, Wong SP, Staals RHJ, et al. 2012. CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3. Mol. Cell 46: 595-605
    • (2012) Mol. Cell , vol.46 , pp. 595-605
    • Westra, E.R.1    Van Erp, P.B.G.2    Künne, T.3    Wong, S.P.4    Staals, R.H.J.5
  • 90
    • 80053169737 scopus 로고    scopus 로고
    • Structures of the RNA-guided surveillance complex from a bacterial immune system
    • Wiedenheft B, Lander GC, Zhou K, Jore MM, Brouns SJJ, et al. 2011. Structures of the RNA-guided surveillance complex from a bacterial immune system. Nature 477: 486-89
    • (2011) Nature , vol.477 , pp. 486-489
    • Wiedenheft, B.1    Lander, G.C.2    Zhou, K.3    Jore, M.M.4    Brouns, S.J.J.5
  • 91
    • 84857097177 scopus 로고    scopus 로고
    • RNA-guided genetic silencing systems in bacteria and archaea
    • Wiedenheft B, Sternberg SH, Doudna JA. 2012. RNA-guided genetic silencing systems in bacteria and archaea. Nature 482: 331-38
    • (2012) Nature , vol.482 , pp. 331-338
    • Wiedenheft, B.1    Sternberg, S.H.2    Doudna, J.A.3
  • 92
    • 79960029056 scopus 로고    scopus 로고
    • RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions
    • Wiedenheft B, van Duijn E, Bultema JB, Waghmare SP, Zhou K, et al. 2011. RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions. PNAS 108: 10092-97
    • (2011) PNAS , vol.108 , pp. 10092-10097
    • Wiedenheft, B.1    Van Duijn, E.2    Bultema, J.B.3    Waghmare, S.P.4    Zhou, K.5
  • 93
    • 79951678159 scopus 로고    scopus 로고
    • Nucleases: Diversity of structure, function and mechanism
    • Yang W. 2011. Nucleases: diversity of structure, function and mechanism. Q. Rev. Biophys. 44: 1-93
    • (2011) Q. Rev. Biophys. , vol.44 , pp. 1-93
    • Yang, W.1
  • 94
    • 84861639567 scopus 로고    scopus 로고
    • Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli
    • Yosef I, Goren MG, Qimron U. 2012. Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli. Nucleic Acids Res. 40: 5569-76
    • (2012) Nucleic Acids Res. , vol.40 , pp. 5569-5576
    • Yosef, I.1    Goren, M.G.2    Qimron, U.3
  • 95
    • 84856778250 scopus 로고    scopus 로고
    • Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity
    • Zhang J, Rouillon C, Kerou M, Reeks J, Brugger K, et al. 2012. Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity. Mol. Cell 45: 303-13
    • (2012) Mol. Cell , vol.45 , pp. 303-313
    • Zhang, J.1    Rouillon, C.2    Kerou, M.3    Reeks, J.4    Brugger, K.5
  • 96
    • 84908445494 scopus 로고    scopus 로고
    • Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
    • Zhao H, Sheng G, Wang J, Wang M, Bunkoczi G, et al. 2014. Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli. Nature 515: 147-50
    • (2014) Nature , vol.515 , pp. 147-150
    • Zhao, H.1    Sheng, G.2    Wang, J.3    Wang, M.4    Bunkoczi, G.5


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