Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing

Biochemical Journal

Volumn 452, Issue 2, 2013, Pages 223-230

  Reeks, Judith ^a   Sokolowski, Richard D ^a   Graham, Shirley ^a   Liu, Huanting ^a   Naismith, James H ^a   White, Malcolm F ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Antiviral defence; Cas6; Clustered regularly interspaced short palindromic repeats (CRISPR); Ribonuclease; Sulfolobus

Indexed keywords

CAS6 ENZYME; DNA; ENZYME; HISTIDINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME STRUCTURE; IMMUNE SYSTEM; METHYLATION; MOLECULAR RECOGNITION; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RNA PROCESSING; STRUCTURE ANALYSIS; SULFOLOBUS SOLFATARICUS;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; BASE SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; INVERTED REPEAT SEQUENCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RIBONUCLEASES; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, ARCHAEAL; SEQUENCE HOMOLOGY, AMINO ACID; SULFOLOBUS SOLFATARICUS;

EID: 84877757610     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130269     Document Type: Article

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