SCOPUS 정보 검색 플랫폼

Volumn 23, Issue 13, 2015, Pages 2975-2981

New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: Biological evaluation and molecular modelling studies

(9) Carradori, Simone a Mollica, Adriano a Ceruso, Mariangela b D'Ascenzio, Melissa c De Monte, Celeste c Chimenti, Paola c Sabia, Rocchina c Akdemir, Atilla d Supuran, Claudiu T b

a UNIVERSITY OF CHIETI (Italy)

b UNIVERSITY OF FLORENCE (Italy)

c SAPIENZA UNIVERSITY OF ROME (Italy)

d BEZMIALEM VAKIF UNIVERSITY (Turkey)

Author keywords

Molecular modelling; Probenecid; Selective carbonic anhydrase IX inhibitors; Selective carbonic anhydrase XII inhibitors; Tertiary sulfonamides

Indexed keywords

4 (N,N DIPROPYLSULFAMOYL) N (2 METHYLBENZAMIDE); 4 (N,N DIPROPYLSULFAMOYL) N (3 METHYLCYCLOHEXYL)BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N (3 MORPHOLINOPROPYL)BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N (4 METHYLCYCLOHEXYL)BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N (4 NITROPHENYL)BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N (BENZYLBENZAMIDE); 4 (N,N DIPROPYLSULFAMOYL) N (PYRIDIN 3 YL)BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N (PYRIDIN 4 YL)BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N ETHYLBENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N [2 (1 PIPERIDINYL)ETHYL]BENZAMIDE; 4 (N,N DIPROPYLSULFAMOYL) N [[2 (N,N DIETHYL)AMINO]ETHYL]BENZAMIDE; ACETAZOLAMIDE; AMIDE; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; ENZYME INHIBITOR; N (2 CHLOROPHENYL) 4 (N,N DIPROPYLSULFAMOYL)BENZAMIDE; PROBENECID; UNCLASSIFIED DRUG; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; PROTEIN BINDING; TUMOR ANTIGEN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG RESPONSE; DRUG STRUCTURE; ENZYME INHIBITION; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR MODEL; PHYSICAL CHEMISTRY; ANALOGS AND DERIVATIVES; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME ASSAY; HUMAN; SENSITIVITY AND SPECIFICITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANTIGENS, NEOPLASM; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ASSAYS; HUMANS; MOLECULAR DOCKING SIMULATION; PROBENECID; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84937428512 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2015.05.013 Document Type: Article

Times cited : (35)

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